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"title": "A Phase II Open-label, Randomized, Three-arm, Multicenter Study of LAG525 Given in Combination With Spartalizumab (PDR001), or With Spartalizumab and Carboplatin, or With Carboplatin, as First or Second Line Therapy in Patients With Advanced Triple-negative Breast Cancer",
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"title": "A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of MT10109L (NivobotulinumtoxinA) for the Treatment of Lateral Canthal Lines",
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"title": "A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of LY3375880 in Adult Subjects With Moderate-to-Severe Atopic Dermatitis: The ADmIRe Study",
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"title": "A Phase II Randomized, Double-blind Placebo-controlled Trial to Determine if Fecal Microbiota Transplantation is Efficacious for Hospitalized Patients With C. Difficile Infection History During Antibiotic Treatment",
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"title": "Potential Benefit for Non Invasive Vagus Nerve Stimulation (nVNS) Using GammaCore in the Treatment of Raynaud's Phenomena.",
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"title": "Adipose Derived Stromal Cell Transplantation as an Adjunct to Arthroscopy in Treatment of Effusion Synovitis of the Early Degenerative Knee",
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"title": "Multicenter, Randomised Study of the Impact of Advanced, Non-invasive Diagnostic Instrumentation for Early Cutaneous Tumor Diagnosis, Clinical-therapeutic Pathways and an Economic-management Perspective",
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"title": "A Phase 3, Prospective, Randomized, Double-blind, Multi-center Study of the Efficacy and Safety of Lanreotide Autogel®/Depot 120 mg Plus BSC vs. Placebo Plus BSC for Tumour Control in Subjects With Well Differentiated, Metastatic and/or Unresectable, Typical or Atypical, Lung Neuroendocrine Tumours",
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"title": "A Multicenter, Double-Blind, Parallel-Arm, Placebo-Controlled, Phase 2 Study of the Efficacy, Safety, and Tolerability of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Recurrence of Clostridium Difficile Infection",
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"title": "An Open-label Phase 2a Study to Evaluate the Safety and Tolerability of Perampanel (E2007) in Subjects With Cervical Dystonia (SAFE-Per CD)",
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"title": "Early Life Interventions for Childhood Growth and Development In Tanzania",
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"title": "Treatment With Lorcaserin for Cocaine Use: The TLC Study",
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"title": "A Clinical Study of the Biofinity Energys Soft Contact Lens in Users of Digital Devices",
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"title": "Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair: a Prospective Randomized Trial",
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"title": "International CoolSculpting: Prospective, Multi-Country, Study to Evaluate Patient Satisfaction for Non-Invasive Fat Reduction in Abdomen and/or Flanks (iCOOL)",
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"title": "Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Pharmacokinetic Profile of CPL-01 in the Management of Acute Postoperative Pain After Mini-abdominoplasty Surgery",
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"title": "Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes",
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"title": "Lipiodol as an Imaging Biomarker of Tumor Necrosis After Transcatheter Chemoembolization Therapy in Patients With Primary and Metastatic Liver Cancer",
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"title": "Efficacy of Bone Marrow Aspirate Concentrate Compared With Platelet Rich Plasma for the Treatment of Symptomatic Knee Osteoarthritis: A Randomized, Controlled Clinical Trial",
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"title": "A Randomized Phase II Study of Co-Expression Extrapolation (COXEN) With Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer",
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"title": "An Extension Study of Intrathecal Enzyme Replacement for Cognitive Decline in Mucopolysaccharidosis I",
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"title": "Denosumab and Teriparatide Study (DATA-HD and DATA-EX)",
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"title": "A Phase I/II Study of the Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors",
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"title": "A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers",
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"sponsor_name": "University of Pennsylvania",
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"title": "Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults",
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"start_date": "2014-12-31",
"completion_date": "2020-02-29",
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"sponsor_name": "University of Oregon",
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"title": "Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling",
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"start_date": "2015-05-31",
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"sponsor_name": "Stanford University",
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"title": "A Prospective, Single Blinded, Multi-center, Randomized, Controlled, Pivotal Study to Assess the Safety and Effectiveness of the InSpace™ Device for Treatment of Full Thickness Massive Rotator Cuff Tears",
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"title": "A Phase 1/2 Study to Assess the Safety and Efficacy of Intratumoral IMO-2125 in Combination With Ipilimumab or Pembrolizumab in Patients With Metastatic Melanoma (ILLUMINATE-204)",
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"title": "rTMS: A Treatment to Restore Function After Severe TBI",
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"title": "Initiation of Continuous Glucose Monitoring at Diagnosis of Type 1 Diabetes",
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"title": "Enhancing Fear Extinction Via Angiotensin Type 1 Receptor Inhibition: A Randomized Controlled Trial in Posttraumatic Stress Disorder",
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"title": "RAPID EC - Randomized Controlled Trial Assessing Pregnancy With Intrauterine Devices for Emergency Contraception",
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"title": "A Phase II Study of Pembrolizumab for Patients With Head and Neck Squamous Cell Carcinoma With Residual Disease Following Definitive Chemoradiation",
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"title": "A Phase 3 Study to Evaluate the Safety and Efficacy of OMS721 for the Treatment of Atypical Hemolytic Uremic Syndrome (aHUS) in Adults and Adolescents",
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"title": "Open-label, Single-center, Prospective Study on the Efficacy and Safety of Repository Corticotropin Injection (H.P. ACTHAR GEL) in the Treatment of Adults With Non-infectious Retinal Vasculitis",
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"sponsor_name": "Ocular Immunology and Uveitis Foundation",
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{
"registry_id": "NCT03653663",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03653663",
"title": "Near Infrared Spectroscopy to Diagnose Statin-Associated Muscle Symptoms",
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"start_date": "2018-01-01",
"completion_date": "2020-02-29",
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"sponsor_name": "Hartford Hospital",
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{
"registry_id": "NCT03416621",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03416621",
"title": "Project Q Pilot: Examining Different Treatment Modalities to Maximize Cessation Efforts for Light Smokers",
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"start_date": "2018-05-17",
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"has_results": true,
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"sponsor_name": "Duke University",
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"days_late": null
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"registry_id": "NCT03586882",
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"title": "Effect of Spinal Cord Stimulation on Gait and Balance in Chronic Low Back Pain Patients With or Without Leg Pain",
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"start_date": "2018-06-15",
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"sponsor_name": "Texas Back Institute",
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"registry_id": "NCT04720547",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04720547",
"title": "Sleep and Breathing in Health and Disease (Part 2A - Chemical Stimuli, Sleep and Breathing in the General Population)",
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"start_date": "2018-07-03",
"completion_date": "2020-02-29",
"has_results": true,
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"sponsor_name": "Wayne State University",
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"days_late": 373
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{
"registry_id": "NCT03572478",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03572478",
"title": "A Phase Ib/IIa Study of Rucaparib (PARP Inhibitor) Combined With Nivolumab in Metastatic Castrate - Resistant Prostate Cancer and Advanced/Recurrent Endometrial Cancer",
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"start_date": "2018-08-14",
"completion_date": "2020-02-29",
"has_results": true,
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"sponsor_name": "University of Chicago",
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"status": "reported",
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"title": "An Open-label Extension Study of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF) - A Long-term Follow-up to Study TDE-HF-301",
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"title": "A Two-Part (Double-Blind Placebo Controlled/Open-Label) Multicenter Study to Evaluate Safety, Tolerability, and Efficacy of Inclisiran in Subjects With Homozygous Familial Hypercholesterolemia (Hofh) (ORION-5)",
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"title": "Investigation of Safety and Efficacy of NNC0174-0833 for Weight Management - a Dose Finding Trial.",
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"title": "Multi-center, Prospective, Randomized, Placebo-Controlled, Delayed Treatment, Double-Blind Study to Evaluate the Effectiveness and Safety of a Single Oral Dose of Solosec® for the Treatment of Trichomoniasis",
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"title": "Compression Wraps as Adjuvant Therapy in the Management of Acute Systolic Heart Failure (CATAS-HF)",
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"title": "A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Trial to Determine the Dose of Caffeine in a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain",
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"title": "The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism With and Without Estrogen and Progesterone Replacement",
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"title": "A Phase 2/3 Multi-center Study to Evaluate the Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory Aggressive B-Cell Non Hodgkin Lymphoma",
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"title": "A Multi-center, Prospective Clinical Trial to Evaluate the Safety and Effectiveness of a Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal",
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"title": "A Phase I/II Study of Palbociclib, Letrozole and T-DM1 in Trastuzumab Refractory Estrogen Receptor Positive (ER+) and HER2 Positive Metastatic Breast Cancer",
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"title": "Bedside Resources to Gauge Intravascular Volume Status in Hypovolemic Infants in the Operating Room",
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"title": "Impact of Preoperative Quadratus Lumborum Block on Recovery Profile After Laparoscopic Ventral Hernia Repair",
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"title": "A Prospective, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation",
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"title": "Effects of Metformin on Mood and Cognition During Nicotine Withdrawal",
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"completion_date": "2020-03-13",
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"sponsor_name": "University of Pennsylvania",
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"title": "The Role of Orexin in Human Panic Disorder",
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"completion_date": "2020-03-13",
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"sponsor_name": "University of California, San Francisco",
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"title": "Randomized Controlled Trial Targeting Noradrenergic Stress Mechanisms in Alcoholism With Doxazosin",
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"title": "A Phase II Clinical Trial Assessing the Safety of an Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast Cancer",
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"sponsor_name": "Washington University School of Medicine",
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"title": "A Phase 2, Multicenter, Randomized, Proof-of-Concept, Double-Blind, Placebo-Controlled, Parallel-Group Study, Including an Open-Label Period, Evaluating the Efficacy and Safety of 1 Subcutaneous Dose Regimen of Fremanezumab for the Treatment of Posttraumatic Headache (PTH)",
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"title": "Effect of GET73 on Magnetic Resonance Spectroscopy Measures of Central Glutamate and GABA and Alcohol Cue-elicited Brain Activation in Recently Abstinent Non-treatment Seeking Individuals With Alcohol Use Disorder.",
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"title": "Biological Effects of Ultrasound Insonification of the Spleen",
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"title": "A Phase IV, Multicenter, Single-Arm, Open-Label Study of Emicizumab Prophylaxis in Patients With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures",
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"start_date": "2018-06-28",
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"title": "Liposomal Bupivacaine Versus Standard Bupivacaine Hydrochloride In Colorectal Surgery",
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"sponsor_name": "Indiana University",
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"title": "Comparison of Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles in the Management of Myofascial Pain Disorder: A Randomized Clinical Trial",
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"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Assess the Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis",
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"title": "A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study Investigating the Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to- Severe Atopic Dermatitis",
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"registry_id": "NCT03602339",
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"title": "LowEr Administered Dose With highEr Relaxivity: Gadovist vs Dotarem (LEADER 75)",
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"title": "A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of MT10109L (NivobotulinumtoxinA) for the Treatment of Glabellar Lines",
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"registry_id": "NCT03832738",
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"title": "A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of JTE-451 Administered for 16 Weeks in Subjects With Moderate to Severe Plaque Psoriasis (IMPACT-PS)",
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"title": "Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation",
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"start_date": "2019-03-25",
"completion_date": "2020-03-13",
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"sponsor_name": "University of Illinois at Chicago",
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{
"registry_id": "NCT02664441",
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"title": "Glucagon-Like Peptide-1 Agonist Effects on Energy Balance in Hypothalamic Obesity",
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"sponsor_name": "Seattle Children's Hospital",
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}