HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 48602,
"recordsTotal": 48602,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=-completion_date&start=44100",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=-completion_date&start=43500",
"results": [
{
"registry_id": "NCT04940299",
"publication_url": "https://clinicaltrials.gov/study/NCT04940299",
"title": "A Phase II Study to Assess the Safety and Efficacy of Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2021-09-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04883463",
"publication_url": "https://clinicaltrials.gov/study/NCT04883463",
"title": "Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury",
"has_exemption": false,
"start_date": "2021-09-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05061238",
"publication_url": "https://clinicaltrials.gov/study/NCT05061238",
"title": "Impact Of Muscle Vibration On Gait Control",
"has_exemption": false,
"start_date": "2021-10-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05009992",
"publication_url": "https://clinicaltrials.gov/study/NCT05009992",
"title": "A Combination Therapy Trial Using an Adaptive Platform Design for Children and Young Adults With Diffuse Midline Gliomas (DMGs) Including Diffuse Intrinsic Pontine Gliomas (DIPGs) at Initial Diagnosis, Post-Radiation Therapy and at Time of Progression",
"has_exemption": false,
"start_date": "2021-10-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04708054",
"publication_url": "https://clinicaltrials.gov/study/NCT04708054",
"title": "Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS",
"has_exemption": false,
"start_date": "2021-10-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04523857",
"publication_url": "https://clinicaltrials.gov/study/NCT04523857",
"title": "A Phase II Pilot Trial of ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer Patients (\"ABBY\")",
"has_exemption": false,
"start_date": "2021-11-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04889716",
"publication_url": "https://clinicaltrials.gov/study/NCT04889716",
"title": "Phase II Study of Dual Targeting of CD19 and CD20 Antigens Using Sequential CD19-directed CAR-T Cells Followed by Mosunetuzumab or Glofitamab in Relapsed or Refractory Diffuse Large B-cell or Transformed Follicular Lymphomas",
"has_exemption": false,
"start_date": "2021-11-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05112861",
"publication_url": "https://clinicaltrials.gov/study/NCT05112861",
"title": "A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus PFS in Subjects With Visual Impairment Due to Retinal Disorders, NORSE SEVEN",
"has_exemption": false,
"start_date": "2021-11-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Outlook Therapeutics, Inc.",
"sponsor_slug": "outlook-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05116930",
"publication_url": "https://clinicaltrials.gov/study/NCT05116930",
"title": "Neostigmine and Glycopyrrolate for the Treatment of Post Dural Puncture Headache After Known Dural Puncture With a Tuohy Needle: A Pilot Study",
"has_exemption": false,
"start_date": "2021-11-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04735627",
"publication_url": "https://clinicaltrials.gov/study/NCT04735627",
"title": "Real-Time Levodopa Monitoring for Improved Management of Parkinson Disease",
"has_exemption": false,
"start_date": "2021-12-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04784052",
"publication_url": "https://clinicaltrials.gov/study/NCT04784052",
"title": "TCRαβ+ T-cell/CD19+ B-cell Depleted Hematopoietic Grafts and a Reduced Intensity Preparative Conditioning Regimen Containing JSP191 (Briquilimab) to Achieve Engraftment and Blood Reconstitution in Patients With Fanconi Anemia",
"has_exemption": false,
"start_date": "2021-12-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Porteus, Matthew, MD",
"sponsor_slug": "porteus-matthew-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05139602",
"publication_url": "https://clinicaltrials.gov/study/NCT05139602",
"title": "A Phase 2 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of Lutikizumab (ABT-981) in Adult Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy: Amended Protocol to Include a Lutikizumab Open-Label Sub-study in Subjects Naïve to Biologic Therapy",
"has_exemption": false,
"start_date": "2021-12-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05118789",
"publication_url": "https://clinicaltrials.gov/study/NCT05118789",
"title": "A Phase 1/2 Study of the Highly Selective ROS1 Inhibitor Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors (ARROS-1)",
"has_exemption": false,
"start_date": "2022-01-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvalent Inc.",
"sponsor_slug": "nuvalent-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04861064",
"publication_url": "https://clinicaltrials.gov/study/NCT04861064",
"title": "Weekly Sirolimus Therapy for the Treatment of Venous and Lymphatic Malformations",
"has_exemption": false,
"start_date": "2022-01-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05253495",
"publication_url": "https://clinicaltrials.gov/study/NCT05253495",
"title": "Reducing the Burden of Oncologic Chemoradiotherapy And Radiation Exposure From Diagnostic Imaging by Utilizing Targeted Immunotherapy in Children, Adolescents and Young Adults With Lymphoma",
"has_exemption": false,
"start_date": "2022-02-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "New York Medical College",
"sponsor_slug": "new-york-medical-college",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05140148",
"publication_url": "https://clinicaltrials.gov/study/NCT05140148",
"title": "Promoting Recovery After STroke With Amantadine",
"has_exemption": false,
"start_date": "2022-02-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04797767",
"publication_url": "https://clinicaltrials.gov/study/NCT04797767",
"title": "A Phase 1/2 Single-Center Trial Combining Venetoclax With G-CSF, Cladribine, Cytarabine, and Mitoxantrone (CLAG-M) for Patients With AML and High-Grade Myeloid Neoplasms",
"has_exemption": false,
"start_date": "2022-02-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05013892",
"publication_url": "https://clinicaltrials.gov/study/NCT05013892",
"title": "Phase II Trial of Normal Tissue Sparing Whole Brain Radiation Therapy (NTS-WBRT) in Patients With Brain Metastases",
"has_exemption": false,
"start_date": "2022-02-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04775706",
"publication_url": "https://clinicaltrials.gov/study/NCT04775706",
"title": "A Multicenter, Proof-of-concept, Phase 2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HM15912 (Sonefpeglutide) in Adult Subjects With Short Bowel Syndrome-associated Intestinal Failure (SBS-IF)",
"has_exemption": false,
"start_date": "2022-03-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hanmi Pharmaceutical Company Limited",
"sponsor_slug": "hanmi-pharmaceutical-company-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04864054",
"publication_url": "https://clinicaltrials.gov/study/NCT04864054",
"title": "An Open-Label, Dose Escalation, Multi-Center Phase I/II Clinical Trial of ECT204 T-Cell Therapy in Adults With Advanced Hepatocellular Carcinoma (HCC) (ARYA-3)",
"has_exemption": false,
"start_date": "2022-03-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eureka Therapeutics Inc.",
"sponsor_slug": "eureka-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04965454",
"publication_url": "https://clinicaltrials.gov/study/NCT04965454",
"title": "Clinical Trial of Biomarkers for Predicting Immunotherapy Response in Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2022-03-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Queen's Medical Center",
"sponsor_slug": "queens-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05303636",
"publication_url": "https://clinicaltrials.gov/study/NCT05303636",
"title": "A Multicenter, Open-label, Controlled Study to Investigate the Effect of Either LF111 or Drospirenone Chewable Tablets on Bone Mineral Density (BMD) in Adolescent and Adult Women in Comparison With Non-users of Hormonal Contraceptive Methods",
"has_exemption": false,
"start_date": "2022-03-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Insud Pharma",
"sponsor_slug": "insud-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04502758",
"publication_url": "https://clinicaltrials.gov/study/NCT04502758",
"title": "A Randomized Controlled Trial of Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation Associated With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2022-04-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05104736",
"publication_url": "https://clinicaltrials.gov/study/NCT05104736",
"title": "A Phase II, Open-Label Trial of PT-112 in Subjects With Thymoma and Thymic Carcinoma",
"has_exemption": false,
"start_date": "2022-04-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05289557",
"publication_url": "https://clinicaltrials.gov/study/NCT05289557",
"title": "A Multicenter Trial of the Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents",
"has_exemption": false,
"start_date": "2022-05-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duchesnay Inc.",
"sponsor_slug": "duchesnay-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05269004",
"publication_url": "https://clinicaltrials.gov/study/NCT05269004",
"title": "A Multicenter, Single-Arm, Open-Label, Extension, Rollover Study To Evaluate The Long-Term Safety And Efficacy Of Ocrelizumab In Patients With Multiple Sclerosis",
"has_exemption": false,
"start_date": "2022-05-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05018585",
"publication_url": "https://clinicaltrials.gov/study/NCT05018585",
"title": "A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Trial to Evaluate the Efficacy and Safety of Diamyd® to Preserve Endogenous Beta Cell Function in Adolescents and Adults With Recently Diagnosed Type 1 Diabetes, Carrying the Genetic HLA DR3-DQ2 Haplotype",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Diamyd Medical AB",
"sponsor_slug": "diamyd-medical-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05384626",
"publication_url": "https://clinicaltrials.gov/study/NCT05384626",
"title": "A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors (ALKOVE-1)",
"has_exemption": false,
"start_date": "2022-06-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvalent Inc.",
"sponsor_slug": "nuvalent-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04981509",
"publication_url": "https://clinicaltrials.gov/study/NCT04981509",
"title": "A Phase 2 Study of Bevacizumab, Erlotinib and Atezolizumab in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Associated or Sporadic Papillary Renal Cell Cancer",
"has_exemption": false,
"start_date": "2022-06-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04789070",
"publication_url": "https://clinicaltrials.gov/study/NCT04789070",
"title": "A Double-Blind Randomised Controlled Trial (dbRCT) Phase III Trial Investigating the Effect of Sirolimus on Disease Progression in Patients With Inclusion Body Myositis (IBM) as Measured by the IBM Functional Rating Scale (IBM-FRS)",
"has_exemption": false,
"start_date": "2022-07-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Kansas Medical Center",
"sponsor_slug": "university-of-kansas-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05371613",
"publication_url": "https://clinicaltrials.gov/study/NCT05371613",
"title": "A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II",
"has_exemption": false,
"start_date": "2022-07-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05512754",
"publication_url": "https://clinicaltrials.gov/study/NCT05512754",
"title": "Randomized Controlled Trial of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen",
"has_exemption": false,
"start_date": "2022-08-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05431270",
"publication_url": "https://clinicaltrials.gov/study/NCT05431270",
"title": "A Phase 1, Open-Label, Dose Escalation and Expansion Study of Mavrostobart (PT199) Administered Alone in Adult Patients with Advanced Solid TuMORs, in CombiNation with a Checkpoint INhibitor TreatinG Wild-type Non-Small Cell Lung Cancer, or in Combination with ChemoTherapy for Metastatic or Advanced PAncreatic Ductal AdenocaRcinoma (MORNINGSTAR)",
"has_exemption": false,
"start_date": "2022-08-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05168566",
"publication_url": "https://clinicaltrials.gov/study/NCT05168566",
"title": "A Multicenter, Open-label, Phase IIb Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC (Non-resistant Uncommon EGFR Mutations Only, Including L861Q, G719X, and/or S768I)",
"has_exemption": false,
"start_date": "2022-09-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Teligene US",
"sponsor_slug": "teligene-us",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05048212",
"publication_url": "https://clinicaltrials.gov/study/NCT05048212",
"title": "A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases",
"has_exemption": false,
"start_date": "2022-09-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05039281",
"publication_url": "https://clinicaltrials.gov/study/NCT05039281",
"title": "Phase I/II Study to Evaluate the Safety and Clinical Efficacy of Atezolizumab (Anti-PD-L1) in Combination With Cabozantinib in Patients With Recurrent Glioblastoma (rGBM)",
"has_exemption": false,
"start_date": "2022-09-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05365035",
"publication_url": "https://clinicaltrials.gov/study/NCT05365035",
"title": "A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts",
"has_exemption": false,
"start_date": "2022-09-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06166836",
"publication_url": "https://clinicaltrials.gov/study/NCT06166836",
"title": "A Phase 1b/II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of D-1553 Combined With IN10018 in Subjects With Locally Advanced or Metastatic Solid Tumors With KRAS G12C Mutation",
"has_exemption": false,
"start_date": "2022-10-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "InxMed (Shanghai) Co., Ltd.",
"sponsor_slug": "inxmed-shanghai-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05286814",
"publication_url": "https://clinicaltrials.gov/study/NCT05286814",
"title": "Phase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma",
"has_exemption": false,
"start_date": "2022-10-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05672849",
"publication_url": "https://clinicaltrials.gov/study/NCT05672849",
"title": "Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases",
"has_exemption": false,
"start_date": "2022-11-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael A Belfort",
"sponsor_slug": "michael-a-belfort",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05534971",
"publication_url": "https://clinicaltrials.gov/study/NCT05534971",
"title": "A Randomized Study Comparing Two Techniques for Central Venous Catheter Insertion",
"has_exemption": false,
"start_date": "2022-11-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05091372",
"publication_url": "https://clinicaltrials.gov/study/NCT05091372",
"title": "Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma",
"has_exemption": false,
"start_date": "2022-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06007872",
"publication_url": "https://clinicaltrials.gov/study/NCT06007872",
"title": "Feasibility: Intracardiac Echocardiography Guided Watchman Device Implant",
"has_exemption": false,
"start_date": "2022-12-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05515536",
"publication_url": "https://clinicaltrials.gov/study/NCT05515536",
"title": "Long-Term Open-Label Study to Assess the Safety and Efficacy of Vatiquinone in Patients With Friedreich Ataxia",
"has_exemption": false,
"start_date": "2022-12-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PTC Therapeutics",
"sponsor_slug": "ptc-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05233397",
"publication_url": "https://clinicaltrials.gov/study/NCT05233397",
"title": "Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA® (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma",
"has_exemption": false,
"start_date": "2022-12-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05632809",
"publication_url": "https://clinicaltrials.gov/study/NCT05632809",
"title": "REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)",
"has_exemption": false,
"start_date": "2023-01-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05512208",
"publication_url": "https://clinicaltrials.gov/study/NCT05512208",
"title": "A Phase 2 Study of VS-6766 (Dual RAF/MEK Inhibitor) Plus Defactinib (FAK Inhibitor) in Recurrent Gynecological Cancers (DURAFAK)",
"has_exemption": false,
"start_date": "2023-02-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05447559",
"publication_url": "https://clinicaltrials.gov/study/NCT05447559",
"title": "Multicentre, Adaptive, Double-blind, Three-arm, Placebo-controlled, Noninferiority Trial Examining Antimicrobial Prophylaxis Duration in Cardiac Surgery",
"has_exemption": false,
"start_date": "2023-02-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Monash University",
"sponsor_slug": "monash-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05518578",
"publication_url": "https://clinicaltrials.gov/study/NCT05518578",
"title": "RENAISSANCE Study: A Phase 2, Multicenter, Open Label Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy",
"has_exemption": false,
"start_date": "2023-02-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Supernus Pharmaceuticals, Inc.",
"sponsor_slug": "supernus-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05676931",
"publication_url": "https://clinicaltrials.gov/study/NCT05676931",
"title": "A Phase II, Open-label, Platform Study, to Evaluate Immunotherapy-based Combinations in Participants With Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2023-02-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05608252",
"publication_url": "https://clinicaltrials.gov/study/NCT05608252",
"title": "A Single Arm Phase 1/2 Trial of Abemaciclib + VS-6766 + Fulvestrant in Metastatic HR+/HER2- Breast Cancer",
"has_exemption": false,
"start_date": "2023-02-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Adrienne G. Waks",
"sponsor_slug": "adrienne-g-waks",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05735483",
"publication_url": "https://clinicaltrials.gov/study/NCT05735483",
"title": "A Phase 3, Multicenter, Long-Term Extension Study to Assess the Safety and Efficacy of Lebrikizumab in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05594563",
"publication_url": "https://clinicaltrials.gov/study/NCT05594563",
"title": "TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes",
"has_exemption": false,
"start_date": "2023-03-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emily K. Sims",
"sponsor_slug": "emily-k-sims",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05482893",
"publication_url": "https://clinicaltrials.gov/study/NCT05482893",
"title": "A Phase 1/2, Open-Label, Dose Escalation and Expansion Study With PT886 (Spevatamig) Followed by a Multi-cohorT Study in Patients With Advanced GastrIc, Gastroesophageal JuNction, Pancreatic Ductal or Biliary Tract AdEnocarcinomas of PT886, in Combination With ChemotherApy, and/or an Immune ChecKpoint Inhibitor. The TWINPEAK Study",
"has_exemption": false,
"start_date": "2023-03-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06010342",
"publication_url": "https://clinicaltrials.gov/study/NCT06010342",
"title": "A Phase 2 Study of TL118 for the Treatment of Patients With Solid Tumors Harboring NTRK Gene Fusions",
"has_exemption": false,
"start_date": "2023-03-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Teligene US",
"sponsor_slug": "teligene-us",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05325242",
"publication_url": "https://clinicaltrials.gov/study/NCT05325242",
"title": "Safety and Efficacy of Elbow Artery Embolization (EAE) for the Treatment of Lateral Epicondylitis",
"has_exemption": false,
"start_date": "2023-03-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Siddharth Padia, MD",
"sponsor_slug": "siddharth-padia-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05786040",
"publication_url": "https://clinicaltrials.gov/study/NCT05786040",
"title": "Phase II Study to Assess the Efficacy of Combined Tafasitamab and Rituximab in Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder",
"has_exemption": false,
"start_date": "2023-03-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Timothy Voorhees",
"sponsor_slug": "timothy-voorhees",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05734313",
"publication_url": "https://clinicaltrials.gov/study/NCT05734313",
"title": "Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes",
"has_exemption": false,
"start_date": "2023-03-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Albert Einstein College of Medicine",
"sponsor_slug": "albert-einstein-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05103345",
"publication_url": "https://clinicaltrials.gov/study/NCT05103345",
"title": "A Phase I/IIa, Open-label, Dose Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Modified Salmonella Typhimurium SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-04-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Guangzhou Sinogen Pharmaceutical Co., Ltd",
"sponsor_slug": "guangzhou-sinogen-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05019703",
"publication_url": "https://clinicaltrials.gov/study/NCT05019703",
"title": "A Phase 2 Trial of Atezolizumab and Cabozantinib in Adolescents and Young Adults With Recurrent/Metastatic Osteosarcoma (TACOS)",
"has_exemption": false,
"start_date": "2023-04-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05551104",
"publication_url": "https://clinicaltrials.gov/study/NCT05551104",
"title": "Safest Choice of Antihypertensive Regimen for Postpartum Hypertension: A Randomized Control Trial (SCARPH)",
"has_exemption": false,
"start_date": "2023-05-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Loma Linda University",
"sponsor_slug": "loma-linda-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05563038",
"publication_url": "https://clinicaltrials.gov/study/NCT05563038",
"title": "Scrambler Therapy for Post-Stroke Pain",
"has_exemption": false,
"start_date": "2023-05-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05586581",
"publication_url": "https://clinicaltrials.gov/study/NCT05586581",
"title": "PET Imaging of Synaptic Density Combined With Neuroimmunologic Measures to Reveal Mechanisms of HIV Neuropathogenesis During ART",
"has_exemption": false,
"start_date": "2023-05-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05726370",
"publication_url": "https://clinicaltrials.gov/study/NCT05726370",
"title": "A Phase 2 Study of Preoperative Pembrolizumab and Chemotherapy Followed by Adjuvant Pembrolizumab in Resectable Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2023-05-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05816603",
"publication_url": "https://clinicaltrials.gov/study/NCT05816603",
"title": "Home-based Post-stroke Fatigue Treatment Using Transcranial Direct Current Stimulation (tDCS)",
"has_exemption": false,
"start_date": "2023-05-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05827523",
"publication_url": "https://clinicaltrials.gov/study/NCT05827523",
"title": "Phase III Randomized Trial of HIPEC in Primary Stage Three & Four Primary Ovarian Cancer After Interval Cytoreductive Surgery (FOCUS, KOV-04)",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Center, Korea",
"sponsor_slug": "national-cancer-center-korea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05885022",
"publication_url": "https://clinicaltrials.gov/study/NCT05885022",
"title": "Feasibility Clinical Evaluation of the Calibreye System",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Myra Vision Inc.",
"sponsor_slug": "myra-vision-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05655312",
"publication_url": "https://clinicaltrials.gov/study/NCT05655312",
"title": "A Phase I/IIa, First-In-Human, Multi-Center, Monotherapy and Combination-Therapy With Nivolumab, Dose-Finding and Dose-Expansion Study of [212Pb]VMT01 Melanocortin-1 Receptor-Targeted, Image-Guided Alpha-Particle Therapy in Subjects With Previously Treated Unresectable or Metastatic Melanoma",
"has_exemption": false,
"start_date": "2023-06-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Perspective Therapeutics",
"sponsor_slug": "perspective-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05964387",
"publication_url": "https://clinicaltrials.gov/study/NCT05964387",
"title": "Effect of Silver Diamine Fluoride on Local Anesthesia Efficacy in Molar Incisor Hypomineralization-affected Molars in Children: A Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2023-06-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06097845",
"publication_url": "https://clinicaltrials.gov/study/NCT06097845",
"title": "Transcranial Ultrasound Via Sonolucent Cranioplasty",
"has_exemption": false,
"start_date": "2023-06-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05893069",
"publication_url": "https://clinicaltrials.gov/study/NCT05893069",
"title": "Ability of Oral Oxandrolone to Aid in Rehabilitation and Outcomes of Multiligament Knee Reconstructions: A Double-Blind, Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2023-07-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "George F. Hatch",
"sponsor_slug": "george-f-hatch",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05645718",
"publication_url": "https://clinicaltrials.gov/study/NCT05645718",
"title": "Phase II Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2023-07-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05501678",
"publication_url": "https://clinicaltrials.gov/study/NCT05501678",
"title": "Randomized Placebo-controlled Crossover Trial of Diphenhydramine for Sleep in Children With Autism",
"has_exemption": false,
"start_date": "2023-08-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05776979",
"publication_url": "https://clinicaltrials.gov/study/NCT05776979",
"title": "Post-Transplant Maintenance Therapy With Isatuximab Plus Lenalidomide for High-Risk Multiple Myeloma Patients",
"has_exemption": false,
"start_date": "2023-08-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05914116",
"publication_url": "https://clinicaltrials.gov/study/NCT05914116",
"title": "A Phase 1/2a, Multicenter, Open-Label, First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1311 in Subjects With Advanced/Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2023-08-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DualityBio Inc.",
"sponsor_slug": "dualitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05939076",
"publication_url": "https://clinicaltrials.gov/study/NCT05939076",
"title": "First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Region Örebro County",
"sponsor_slug": "region-orebro-county",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05999630",
"publication_url": "https://clinicaltrials.gov/study/NCT05999630",
"title": "The Use of Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Who Are Treated With Radioactive Iodine for Thyroid Cancer",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05864118",
"publication_url": "https://clinicaltrials.gov/study/NCT05864118",
"title": "A Comparative Evaluation of Specimen Adequacy of a Traditional Nasopharyngeal Swab as Compared to Nasopharyngeal Saline Wash, Saliva, and Serum to Test for Respiratory Viruses and Antibody Response",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05652686",
"publication_url": "https://clinicaltrials.gov/study/NCT05652686",
"title": "An Open-label, Multicenter, Dose Escalation, and Dose Expansion Phase 1/2 Study With Peluntamig (PT217) Followed by a Key ChemotherapY and/or Checkpoint Inhibitor ComBination in Patients With NeuRoendocrIne Carcinomas That Are Known to be DLL3 expressinG CancErs (SKYBRIDGE)",
"has_exemption": false,
"start_date": "2023-09-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05759728",
"publication_url": "https://clinicaltrials.gov/study/NCT05759728",
"title": "A Phase 1/2a, Multicenter, Open-Label, Dose Escalation and Expansion Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Adult Subjects With Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2023-10-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Carina Biotech Limited",
"sponsor_slug": "carina-biotech-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06725758",
"publication_url": "https://clinicaltrials.gov/study/NCT06725758",
"title": "A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours",
"has_exemption": false,
"start_date": "2023-10-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Orion Corporation, Orion Pharma",
"sponsor_slug": "orion-corporation-orion-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05905224",
"publication_url": "https://clinicaltrials.gov/study/NCT05905224",
"title": "A Randomized Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol on the Predictability of Orthodontic Tooth Movement",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072703",
"publication_url": "https://clinicaltrials.gov/study/NCT06072703",
"title": "A Randomized, Sham-Controlled Clinical Trial Evaluating Individualized Neuromodulation of Cortical Regions Involved in Neurogenic Overactive Bladder in Multiple Sclerosis",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07265596",
"publication_url": "https://clinicaltrials.gov/study/NCT07265596",
"title": "Early Longitudinal Imaging in the Parkinson's Progression Markers Initiative Using [18F] AV-133 (PPMI AV-133 Prodromal Imaging)",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael J. Fox Foundation for Parkinson's Research",
"sponsor_slug": "michael-j-fox-foundation-for-parkinsons-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06004115",
"publication_url": "https://clinicaltrials.gov/study/NCT06004115",
"title": "Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression",
"has_exemption": false,
"start_date": "2023-11-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Laureate Institute for Brain Research, Inc.",
"sponsor_slug": "laureate-institute-for-brain-research-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072612",
"publication_url": "https://clinicaltrials.gov/study/NCT06072612",
"title": "Randomized, Open-Label Study of the Bria-IMT Regimen and Check Point Inhibitor vs Physicians' Choice in Advanced Metastatic Breast Cancer.",
"has_exemption": false,
"start_date": "2023-12-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BriaCell Therapeutics Corporation",
"sponsor_slug": "briacell-therapeutics-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05988411",
"publication_url": "https://clinicaltrials.gov/study/NCT05988411",
"title": "Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation - Redo Ablation Procedures: A Pilot Study",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vivek Reddy",
"sponsor_slug": "vivek-reddy",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05734105",
"publication_url": "https://clinicaltrials.gov/study/NCT05734105",
"title": "An International, Phase 3, Randomized, Multicenter, Open-label Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With KIT Exon 11 and Co-occurring KIT Exons 17 and/or 18 Mutations Who Were Previously Treated With Imatinib",
"has_exemption": false,
"start_date": "2023-12-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Deciphera Pharmaceuticals LLC",
"sponsor_slug": "deciphera-pharmaceuticals-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06128629",
"publication_url": "https://clinicaltrials.gov/study/NCT06128629",
"title": "MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2023-12-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intellia Therapeutics",
"sponsor_slug": "intellia-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06100705",
"publication_url": "https://clinicaltrials.gov/study/NCT06100705",
"title": "A Single Arm Open-label, Phase II Study of Sipuleucel-T With Bipolar Androgen Therapy in Men With Metastatic Castration-resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2023-12-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06010329",
"publication_url": "https://clinicaltrials.gov/study/NCT06010329",
"title": "A Multicenter, Open-label, Phase 2 Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC (Uncommon EGFR Mutations Only)",
"has_exemption": false,
"start_date": "2023-12-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Teligene US",
"sponsor_slug": "teligene-us",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072807",
"publication_url": "https://clinicaltrials.gov/study/NCT06072807",
"title": "Brain [18F]-FES PET/CT in the Diagnosis, Treatment Planning and Response Assessment of Brain Metastases in Patients With Estrogen-Receptor Positive Breast Cancer",
"has_exemption": false,
"start_date": "2023-12-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05761171",
"publication_url": "https://clinicaltrials.gov/study/NCT05761171",
"title": "A Phase 2 Study of SNDX-5613 in Combination With Chemotherapy for Patients With Relapsed or Refractory KMT2A-Rearranged Infant Leukemia",
"has_exemption": false,
"start_date": "2024-01-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05641844",
"publication_url": "https://clinicaltrials.gov/study/NCT05641844",
"title": "A Prospective, Multi-Center, Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02, For the Management of Anal Fistulas",
"has_exemption": false,
"start_date": "2024-01-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "RedDress Ltd.",
"sponsor_slug": "reddress-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06311513",
"publication_url": "https://clinicaltrials.gov/study/NCT06311513",
"title": "Multi-Center Pilot Study to Evaluate Concentrated Bone Marrow Aspirate (cBMA) as a Treatment to Modify Post-Traumatic Osteoarthritis (PTOA) Following Revision Anterior Cruciate Ligament Reconstruction (ACLR)",
"has_exemption": false,
"start_date": "2024-01-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital for Special Surgery, New York",
"sponsor_slug": "hospital-for-special-surgery-new-york",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06079398",
"publication_url": "https://clinicaltrials.gov/study/NCT06079398",
"title": "A Phase 2, Multicenter, Double-Blind, Randomized, Placebo-controlled Trial, Evaluating Safety, Tolerability, and Efficacy of Subcutaneous Doses of TransCon CNP Administered Once Weekly for 52 Weeks in Infants (0 to <2 Years of Age) With Achondroplasia Followed by an Open Label Extension (OLE) Period",
"has_exemption": false,
"start_date": "2024-01-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ascendis Pharma A/S",
"sponsor_slug": "ascendis-pharma-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06229210",
"publication_url": "https://clinicaltrials.gov/study/NCT06229210",
"title": "An Open-label, Multicenter Trial to Assess the Safety and Tolerability of Lumateperone in the Treatment of Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder",
"has_exemption": false,
"start_date": "2024-01-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06474637",
"publication_url": "https://clinicaltrials.gov/study/NCT06474637",
"title": "Prospective Clinical Evaluation of the AEON Endoscopic Stapler Powered Handle and Reload in Primary Sleeve Gastrectomy",
"has_exemption": false,
"start_date": "2024-01-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lexington Medical Inc.",
"sponsor_slug": "lexington-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05669170",
"publication_url": "https://clinicaltrials.gov/study/NCT05669170",
"title": "Evaluating Safety and Potential Benefit of Methylphenidate as a Symptomatic Treatment for Apathy in Veterans With Parkinson's Disease.",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ralph H. Johnson VA Medical Center",
"sponsor_slug": "ralph-h-johnson-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05421676",
"publication_url": "https://clinicaltrials.gov/study/NCT05421676",
"title": "Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia",
"has_exemption": false,
"start_date": "2024-02-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06394284",
"publication_url": "https://clinicaltrials.gov/study/NCT06394284",
"title": "IISPT2: Examining 3,4-methylenedioxymethamphetamine (MDMA) Effects on Psychological, Relational and Hyperarousal-Related Neural Reactivity Mechanisms in Veterans With PTSD and MI",
"has_exemption": false,
"start_date": "2024-02-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Herzog Hospital",
"sponsor_slug": "herzog-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06176989",
"publication_url": "https://clinicaltrials.gov/study/NCT06176989",
"title": "Phase II Study of Enasidenib in IDH2-mutated Malignant Sinonasal and Skull Base Tumors",
"has_exemption": false,
"start_date": "2024-03-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05523817",
"publication_url": "https://clinicaltrials.gov/study/NCT05523817",
"title": "Probing the Functional and Behavioral Impact of Precision Circuit Modulation in Neuropsychiatric Diseases",
"has_exemption": false,
"start_date": "2024-03-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05509777",
"publication_url": "https://clinicaltrials.gov/study/NCT05509777",
"title": "A Phase 3, Multicenter, Randomized Clinical Study to Evaluate Mirikizumab in Pediatric Crohn's Disease",
"has_exemption": false,
"start_date": "2024-03-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06108232",
"publication_url": "https://clinicaltrials.gov/study/NCT06108232",
"title": "Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma",
"has_exemption": false,
"start_date": "2024-03-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05493215",
"publication_url": "https://clinicaltrials.gov/study/NCT05493215",
"title": "A Phase 2 Study of Imatinib Therapeutic Drug Monitoring in Gastrointestinal Stromal Tumor",
"has_exemption": false,
"start_date": "2024-03-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Reema A. Patel",
"sponsor_slug": "reema-a-patel",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06425471",
"publication_url": "https://clinicaltrials.gov/study/NCT06425471",
"title": "A Prospective Study on the Efficacy of the Karl Storz Curved Fetoscope (11508aak) and Its Straight Version (11506akk) for In-utero Surgery",
"has_exemption": false,
"start_date": "2024-04-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06368700",
"publication_url": "https://clinicaltrials.gov/study/NCT06368700",
"title": "The HYALEX Freestyle™ Resurfacing System Pivotal Study: A Multicenter, Single-Arm, Pivotal Study of the HYALEX Freestyle Resurfacing Implant",
"has_exemption": false,
"start_date": "2024-04-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hyalex Orthopaedics, Inc.",
"sponsor_slug": "hyalex-orthopaedics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06255782",
"publication_url": "https://clinicaltrials.gov/study/NCT06255782",
"title": "A Phase 1/2/3 First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Efficacy of a Single Intravenous (IV) Administration of ECUR-506 in Males Less Than 9 Months of Age With Genetically Confirmed Neonatal Onset Ornithine Transcarbamylase (OTC) Deficiency",
"has_exemption": false,
"start_date": "2024-04-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "iECURE, Inc.",
"sponsor_slug": "iecure-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06365788",
"publication_url": "https://clinicaltrials.gov/study/NCT06365788",
"title": "A Multicenter Single Arm Phase II Study With Bicalutamide in Combination With Abemaciclib in 4 Cohorts of Locoregionally Advanced Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer",
"has_exemption": false,
"start_date": "2024-04-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Universitaire Ziekenhuizen KU Leuven",
"sponsor_slug": "universitaire-ziekenhuizen-ku-leuven",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05576974",
"publication_url": "https://clinicaltrials.gov/study/NCT05576974",
"title": "A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)",
"has_exemption": false,
"start_date": "2024-04-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06250985",
"publication_url": "https://clinicaltrials.gov/study/NCT06250985",
"title": "New Treatment of Cardiovascular Implantable Electronic Device (CIED) Infections; Immediate Reimplantation After Removal of Infected System",
"has_exemption": false,
"start_date": "2024-04-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rigshospitalet, Denmark",
"sponsor_slug": "rigshospitalet-denmark",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06383013",
"publication_url": "https://clinicaltrials.gov/study/NCT06383013",
"title": "Phase II Study to Evaluate the Efficacy and Safety of Topical BB-101 for the Treatment of Diabetic Lower Leg and Foot Ulcers",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Blue Blood Biotech Corp.",
"sponsor_slug": "blue-blood-biotech-corp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06712849",
"publication_url": "https://clinicaltrials.gov/study/NCT06712849",
"title": "Multi-day Effect of Noninvasive Brain Stimulation in Adults With Amblyopia",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Midwestern University",
"sponsor_slug": "midwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06418282",
"publication_url": "https://clinicaltrials.gov/study/NCT06418282",
"title": "An Open-label, Multi-center, Prospective VA Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/Phlebolymphedema",
"has_exemption": false,
"start_date": "2024-05-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Koya Medical, Inc.",
"sponsor_slug": "koya-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06158841",
"publication_url": "https://clinicaltrials.gov/study/NCT06158841",
"title": "A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapies in Subjects With Relapsed or Refractory Multiple Myeloma (3L+ RRMM Monotherapy Study)",
"has_exemption": false,
"start_date": "2024-05-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06303505",
"publication_url": "https://clinicaltrials.gov/study/NCT06303505",
"title": "A First-in-human Dose Escalation and Optimization Phase I/IIa Study to Investigate Safety, Tolerability, PK, and Efficacy of the NaPi2b ADC TUB-040 in Patients With Platinum-resistant High-grade Ovarian Cancer (PROC) or r/r Adenocarcinoma Non-small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2024-06-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tubulis GmbH",
"sponsor_slug": "tubulis-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06083857",
"publication_url": "https://clinicaltrials.gov/study/NCT06083857",
"title": "An Open-Label Phase I/II Study to Evaluate the Safety and prelimiBasnary Efficacy of Amivantamab and Tepotinib Combination in MET-altered Non-small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2024-06-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06500273",
"publication_url": "https://clinicaltrials.gov/study/NCT06500273",
"title": "A Randomized, Open-label Study Evaluating the Efficacy and Safety of Cemacabtagene Ansegedleucel in Participants With Minimal Residual Disease After Response to First Line Therapy for Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2024-06-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Allogene Therapeutics",
"sponsor_slug": "allogene-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06388733",
"publication_url": "https://clinicaltrials.gov/study/NCT06388733",
"title": "A Phase 3, Open-label, Randomized 2-arm Study Comparing the Clinical Efficacy and Safety of Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma",
"has_exemption": false,
"start_date": "2024-06-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ivy Brain Tumor Center",
"sponsor_slug": "ivy-brain-tumor-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06263231",
"publication_url": "https://clinicaltrials.gov/study/NCT06263231",
"title": "A Multicenter, Randomized, Phase 3 Study to Assess the Efficacy and Safety of INtratumorally Administered INT230-6 (SHAO, VINblastine, CIsplatin) Compared With US Standard of Care in Adults With Locally Recurrent, InoperaBLE, or Metastatic Soft Tissue Sarcomas (INVINCIBLE-3)",
"has_exemption": false,
"start_date": "2024-06-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intensity Therapeutics, Inc.",
"sponsor_slug": "intensity-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05782244",
"publication_url": "https://clinicaltrials.gov/study/NCT05782244",
"title": "Phase 2 Randomized Controlled Trial of Sildenafil Citrate for Treatment of Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2024-07-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06520345",
"publication_url": "https://clinicaltrials.gov/study/NCT06520345",
"title": "A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lutetium (177Lu) Rosopatamab Tetraxetan in Combination With Standard of Care Versus Standard of Care Alone in Patients With PSMA Positive Metastatic Castration-Resistant Prostate Cancer Previously After Androgen Receptor Pathway Inhibitor Treatment",
"has_exemption": false,
"start_date": "2024-07-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Telix Pharmaceuticals (Innovations) Pty Limited",
"sponsor_slug": "telix-pharmaceuticals-innovations-pty-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06211504",
"publication_url": "https://clinicaltrials.gov/study/NCT06211504",
"title": "Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity: a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-07-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Region Skane",
"sponsor_slug": "region-skane",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06174038",
"publication_url": "https://clinicaltrials.gov/study/NCT06174038",
"title": "Early Age-Related Hearing Loss Investigation (EARHLI): A Randomized Controlled Trial to Assess the Mechanisms Linking Early Age-Related Hearing Loss and Alzheimer's Disease and Related Dementias",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06216249",
"publication_url": "https://clinicaltrials.gov/study/NCT06216249",
"title": "A Phase 2 Randomized Trial in Patients With Metastatic Castration Resistant Prostate Cancer to Determine the Efficacy of a Flexible Dosing Schedule of Lu-PSMA Treatment up to 12 Cycles Including Potential Treatment Holiday Periods in Comparison to the Standard Fixed Dosing Schedule of Six Cycles Every Six Weeks (FLEX-MRT)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06027996",
"publication_url": "https://clinicaltrials.gov/study/NCT06027996",
"title": "Absorbable Antibacterial Soft Tissue Support in Breast Reconstruction With Infection Outcomes Assessment (ARIA)",
"has_exemption": false,
"start_date": "2024-08-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Melodi Health, Inc.",
"sponsor_slug": "melodi-health-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06330805",
"publication_url": "https://clinicaltrials.gov/study/NCT06330805",
"title": "A Comparison of Orgovyx (Relugolix) vs Eligard (Leuprolide) on Cardiovascular Function and Biomarkers During Standard of Care Combined ADT (Androgen Deprivation Therapy)-Radiation for Prostate Cancer",
"has_exemption": false,
"start_date": "2024-08-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University Comprehensive Cancer Center",
"sponsor_slug": "ohio-state-university-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06362369",
"publication_url": "https://clinicaltrials.gov/study/NCT06362369",
"title": "A Phase 1b/2a Multi-Center, Dose Escalation and Reference Regimen-Controlled, Multi-Cohort Study to Determine the Safety and Efficacy of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy in Patients With Locally Advanced or Metastatic Cancers Following One or More Prior Therapies",
"has_exemption": false,
"start_date": "2024-08-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "7 Hills Pharma, LLC",
"sponsor_slug": "7-hills-pharma-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06548542",
"publication_url": "https://clinicaltrials.gov/study/NCT06548542",
"title": "A Phase 2a Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects With Moderate to Severe Crohn's Disease",
"has_exemption": false,
"start_date": "2024-09-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05554393",
"publication_url": "https://clinicaltrials.gov/study/NCT05554393",
"title": "A Measurable Residual Disease (MRD) Focused, Phase II Study of Venetoclax Plus Chemotherapy for Newly Diagnosed Younger Patients With Intermediate Risk Acute Myeloid Leukemia: A Tier 1 MYELOMATCH SubStudy",
"has_exemption": false,
"start_date": "2024-09-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06515184",
"publication_url": "https://clinicaltrials.gov/study/NCT06515184",
"title": "Coenzyme Q10 for Gulf War Illness: A Replication Study",
"has_exemption": false,
"start_date": "2024-09-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06630702",
"publication_url": "https://clinicaltrials.gov/study/NCT06630702",
"title": "Application of Thoracic Epidural Spinal Cord Stimulation (SCS) for Managing Freezing of Gait (FOG) in Patients With Advanced Parkinson's Disease",
"has_exemption": false,
"start_date": "2024-09-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Taiwan University Hospital",
"sponsor_slug": "national-taiwan-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06160791",
"publication_url": "https://clinicaltrials.gov/study/NCT06160791",
"title": "Frontline Ruxolitinib With De-Intensified HLH-94 for Adult Hemophagocytic Lymphohistiocytosis (HLH): A Multicenter, Single-Arm Phase 2 Study",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jerry Lee, MD, MSc, MPhil",
"sponsor_slug": "jerry-lee-md-msc-mphil",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06598943",
"publication_url": "https://clinicaltrials.gov/study/NCT06598943",
"title": "An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination With Mirikizumab for the Treatment of Adult Patients With Moderately to Severely Active Ulcerative Colitis",
"has_exemption": false,
"start_date": "2024-10-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06581432",
"publication_url": "https://clinicaltrials.gov/study/NCT06581432",
"title": "Beamion PANTUMOR-1: A Phase II, Multicentre, Multicohort, Open-label Trial to Evaluate the Efficacy and Safety of Oral Zongertinib (BI 1810631) for the Treatment of Selected HER2-mutated or Overexpressed/Amplified Solid Tumours",
"has_exemption": false,
"start_date": "2024-10-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06329570",
"publication_url": "https://clinicaltrials.gov/study/NCT06329570",
"title": "A Prospective, Open-Label, Single-Arm Pilot Study to Evaluate the Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NaviFUS Corporation",
"sponsor_slug": "navifus-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06511141",
"publication_url": "https://clinicaltrials.gov/study/NCT06511141",
"title": "Sacral Neuromodulation for Male Overactive Bladder",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Axonics, Inc.",
"sponsor_slug": "axonics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06561321",
"publication_url": "https://clinicaltrials.gov/study/NCT06561321",
"title": "An Open-label, Phase II Study to Evaluate the Clinical Efficacy and Safety of Tapinarof for Adult Patients With Palmoplantar Keratoderma",
"has_exemption": false,
"start_date": "2024-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06457503",
"publication_url": "https://clinicaltrials.gov/study/NCT06457503",
"title": "Single-Arm Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Recurrent Metastatic Nasopharyngeal Carcinoma Systemic Treatment Naïve Participants",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Coherus Oncology, Inc.",
"sponsor_slug": "coherus-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06479239",
"publication_url": "https://clinicaltrials.gov/study/NCT06479239",
"title": "Phase I/II Study of Anti-CD3 x Anti-EGFR Bispecific Antibody (EGFRBi) Armed Fresh Peripheral Blood Mononuclear Cells (EGFR FPBMC) in Metastatic or Unresectable Pancreatic Cancer",
"has_exemption": false,
"start_date": "2024-11-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06639074",
"publication_url": "https://clinicaltrials.gov/study/NCT06639074",
"title": "MC1963 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for Patients With Advanced Stage Ovarian Cancer: A Phase II Double-Blind Randomized Clinical Trial (FAROUT)",
"has_exemption": false,
"start_date": "2024-11-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06648174",
"publication_url": "https://clinicaltrials.gov/study/NCT06648174",
"title": "The Project for Managing Cardiometabolic Risk in Women Diagnosed With Gestational Diabetes Mellitus: The Development and Application of \"a Lifestyle Intervention Based on Health Belief Model Supported by Mobile Health\"",
"has_exemption": false,
"start_date": "2024-11-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Taiwan University Hospital",
"sponsor_slug": "national-taiwan-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06462729",
"publication_url": "https://clinicaltrials.gov/study/NCT06462729",
"title": "A Randomized Study of LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)",
"has_exemption": false,
"start_date": "2024-11-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Locate Bio Pty Ltd",
"sponsor_slug": "locate-bio-pty-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06484920",
"publication_url": "https://clinicaltrials.gov/study/NCT06484920",
"title": "A Phase II Study of the Combination of Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Relapsed Hodgkin Lymphoma (HL) and B-Non-Hodgkin- Lymphoma (B-NHL)",
"has_exemption": false,
"start_date": "2024-11-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rita Assi",
"sponsor_slug": "rita-assi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06720038",
"publication_url": "https://clinicaltrials.gov/study/NCT06720038",
"title": "A Phase 2, Randomized, Double-Blind, Active-Controlled, Dose-Finding Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 in Healthy Infants Given 4 Doses at 2, 4, 6, and 12-15 Months of Age Concomitantly With Routine Pediatric Vaccines",
"has_exemption": false,
"start_date": "2024-11-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vaxcyte, Inc.",
"sponsor_slug": "vaxcyte-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06748001",
"publication_url": "https://clinicaltrials.gov/study/NCT06748001",
"title": "An Open-label, Multicenter, Rollover Study in Patients Who Participated in an Avapritinib Clinical Study",
"has_exemption": false,
"start_date": "2024-11-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Blueprint Medicines Corporation",
"sponsor_slug": "blueprint-medicines-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682351",
"publication_url": "https://clinicaltrials.gov/study/NCT06682351",
"title": "Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention",
"has_exemption": false,
"start_date": "2024-11-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06721520",
"publication_url": "https://clinicaltrials.gov/study/NCT06721520",
"title": "Comparative Effectiveness of Intrapyloric Botulinum Toxin Injection Versus Pyloromyotomy for Pyloric Drainage During Esophagectomy: A Registry-Based, Pragmatic Randomized Noninferiority Trial",
"has_exemption": false,
"start_date": "2024-12-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06693323",
"publication_url": "https://clinicaltrials.gov/study/NCT06693323",
"title": "Single-Center Evaluation of the Clinical and Radiological Benefit of AHCC® in Combination with Standard of Care Treatment for HPV-Positive Patients with Head and Neck Squamous Cell Carcinoma (HNSCC)",
"has_exemption": false,
"start_date": "2024-12-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06542757",
"publication_url": "https://clinicaltrials.gov/study/NCT06542757",
"title": "Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy (TUMORNATOR I)",
"has_exemption": false,
"start_date": "2024-12-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06636734",
"publication_url": "https://clinicaltrials.gov/study/NCT06636734",
"title": "A Phase II Trial Of Lovastatin And Pembrolizumab In Patients With RM HNSCC (LAPP)",
"has_exemption": false,
"start_date": "2024-12-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06731764",
"publication_url": "https://clinicaltrials.gov/study/NCT06731764",
"title": "Novel Approaches to the Treatment of Hypothyroidism",
"has_exemption": false,
"start_date": "2024-12-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "UConn Health",
"sponsor_slug": "uconn-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06627179",
"publication_url": "https://clinicaltrials.gov/study/NCT06627179",
"title": "A Two-Year Double-masked, Randomized, Sham-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene",
"has_exemption": false,
"start_date": "2024-12-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Laboratoires Thea",
"sponsor_slug": "laboratoires-thea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06578156",
"publication_url": "https://clinicaltrials.gov/study/NCT06578156",
"title": "Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)",
"has_exemption": false,
"start_date": "2024-12-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06741085",
"publication_url": "https://clinicaltrials.gov/study/NCT06741085",
"title": "ICON-RT: Intracranial Consolidation and Deferral of Radiation Therapy in Patients Receiving Approved CNS-Active Systemic Therapeutics",
"has_exemption": false,
"start_date": "2024-12-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325435",
"publication_url": "https://clinicaltrials.gov/study/NCT07325435",
"title": "Beta Cell Function in Type 2 Diabetes in Black Patients: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists",
"has_exemption": false,
"start_date": "2024-12-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "MaryAnn Banerji",
"sponsor_slug": "maryann-banerji",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06771544",
"publication_url": "https://clinicaltrials.gov/study/NCT06771544",
"title": "Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma",
"has_exemption": false,
"start_date": "2024-12-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06756308",
"publication_url": "https://clinicaltrials.gov/study/NCT06756308",
"title": "A Phase 2 Study of Enasidenib in IDH2-Mutant Angioimmunoblastic T-Cell Lymphoma",
"has_exemption": false,
"start_date": "2024-12-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06390319",
"publication_url": "https://clinicaltrials.gov/study/NCT06390319",
"title": "SJALL23T: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)",
"has_exemption": false,
"start_date": "2024-12-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Jude Children's Research Hospital",
"sponsor_slug": "st-jude-childrens-research-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06752616",
"publication_url": "https://clinicaltrials.gov/study/NCT06752616",
"title": "Advancing the Quality of Treatment and Care for Acute Agitation in Emergency Psychiatry",
"has_exemption": false,
"start_date": "2024-12-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lone Baandrup",
"sponsor_slug": "lone-baandrup",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06694350",
"publication_url": "https://clinicaltrials.gov/study/NCT06694350",
"title": "Safety and Efficacy of Pembrolizumab in Combination with Flutamide Treatment for Advanced/Recurrence / Metastasis Head and Neck Squamous Cell Carcinoma: a Single-arm Clinical Study Trial",
"has_exemption": false,
"start_date": "2024-12-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zhejiang Provincial People's Hospital",
"sponsor_slug": "zhejiang-provincial-peoples-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06668584",
"publication_url": "https://clinicaltrials.gov/study/NCT06668584",
"title": "A Phase II Open-label Study of Olutasidenib Post-transplant Maintenance Therapy for Patients With IDH1-mutated Myeloid Malignancies",
"has_exemption": false,
"start_date": "2024-12-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06680869",
"publication_url": "https://clinicaltrials.gov/study/NCT06680869",
"title": "Early Amiodarone in Shockable Cardiac Arrest (Early-Amio) Study",
"has_exemption": false,
"start_date": "2025-01-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oregon Health and Science University",
"sponsor_slug": "oregon-health-and-science-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281742",
"publication_url": "https://clinicaltrials.gov/study/NCT07281742",
"title": "Amblyopia Treatment for Children Aged 8 to 12 Years",
"has_exemption": false,
"start_date": "2025-01-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Retina Foundation of the Southwest",
"sponsor_slug": "retina-foundation-of-the-southwest",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06739122",
"publication_url": "https://clinicaltrials.gov/study/NCT06739122",
"title": "A Phase 3, Open-Label, Multicenter, Single-Arm Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Dulaglutide 3.0 mg and 4.5 mg in Pediatric Participants 10 to Less Than 18 Years of Age With Type 2 Diabetes Mellitus",
"has_exemption": false,
"start_date": "2025-01-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06824064",
"publication_url": "https://clinicaltrials.gov/study/NCT06824064",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study of RBS2418 Plus Best Supportive Care (BSC) in Subjects With Advanced, Metastatic, and Progressive Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-01-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Riboscience, LLC.",
"sponsor_slug": "riboscience-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06707090",
"publication_url": "https://clinicaltrials.gov/study/NCT06707090",
"title": "A Phase 3 Randomized, Parallel Group, Double-Blind Study to Evaluate the Efficacy, Tolerability, and Safety of TR987® 0.1% Gel Versus Standard of Care in the Treatment of Chronic Venous Insufficiency Leg Ulcers (VLU)",
"has_exemption": false,
"start_date": "2025-01-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "TR Therapeutics",
"sponsor_slug": "tr-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06803875",
"publication_url": "https://clinicaltrials.gov/study/NCT06803875",
"title": "A Phase 1/2 Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma",
"has_exemption": false,
"start_date": "2025-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Roberto Chiarle",
"sponsor_slug": "roberto-chiarle",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06748404",
"publication_url": "https://clinicaltrials.gov/study/NCT06748404",
"title": "A Phase 2 Randomized Study of TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus",
"has_exemption": false,
"start_date": "2025-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06709014",
"publication_url": "https://clinicaltrials.gov/study/NCT06709014",
"title": "A 6-month & 18-month Prospective, Randomized, Placebo-controlled, Double-blind Dual Clinical Trial Investigating Efficacy and Safety of Buntanetap in Treating Participants of Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2025-02-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Annovis Bio Inc.",
"sponsor_slug": "annovis-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06668571",
"publication_url": "https://clinicaltrials.gov/study/NCT06668571",
"title": "Central and Peripheral GABA and Glutamate Modulation With Intravenous Ketamine for Treatment-Resistant Depression (G2K): A Randomized, Double-Blind, Placebo-Controlled Study",
"has_exemption": false,
"start_date": "2025-02-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06630728",
"publication_url": "https://clinicaltrials.gov/study/NCT06630728",
"title": "Addiction Potential of Very Low Nicotine Filtered Little Cigars",
"has_exemption": false,
"start_date": "2025-02-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University Comprehensive Cancer Center",
"sponsor_slug": "ohio-state-university-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06814938",
"publication_url": "https://clinicaltrials.gov/study/NCT06814938",
"title": "A Novel Precision Medicine Approach For Obesity: A Randomized, Multi-Center Trial",
"has_exemption": false,
"start_date": "2025-02-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06849986",
"publication_url": "https://clinicaltrials.gov/study/NCT06849986",
"title": "Tislelizumab Combined With Liposomal Doxorubicin and Ifosfamide as First-line Treatment for Patients With Specified Subtypes of Unresectable or Metastatic Soft Tissue Sarcoma: a Multi-center, Single-arm, Prospective Phase II Clinical Trial",
"has_exemption": false,
"start_date": "2025-02-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fudan University",
"sponsor_slug": "fudan-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843811",
"publication_url": "https://clinicaltrials.gov/study/NCT06843811",
"title": "A Pilot Phase 2 Study With Long-Term Extension to Assess the Safety and Efficacy of Sirolimus in Patients With Leigh Syndrome Caused by Genetically-Confirmed Mitochondrial Respiratory Chain Deficiency",
"has_exemption": false,
"start_date": "2025-02-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Matthew Demczko",
"sponsor_slug": "matthew-demczko",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07197502",
"publication_url": "https://clinicaltrials.gov/study/NCT07197502",
"title": "CLINICAL TRIAL: Treatment of Borderline Personality Disorder by Targeting Ventrolateral Prefrontal-amygdala Circuit With Network-based Neuronavigated Transcranial Magnetic Stimulation",
"has_exemption": false,
"start_date": "2025-03-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06673056",
"publication_url": "https://clinicaltrials.gov/study/NCT06673056",
"title": "Effects of N-Acetyl-L-Leucine on Ataxia-Telangiectasia (A-T: A Phase III, Randomized, Placebo-controlled, Double-blind, Crossover Study",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IntraBio Inc",
"sponsor_slug": "intrabio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06942520",
"publication_url": "https://clinicaltrials.gov/study/NCT06942520",
"title": "A Randomized, Open Label, Controlled, Phase 2 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 AAV Gene Therapy Administered Via Subretinal Delivery in Participants With Center Involved Diabetic Macular Edema",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sierra Eye Associates",
"sponsor_slug": "sierra-eye-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06529835",
"publication_url": "https://clinicaltrials.gov/study/NCT06529835",
"title": "A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair (NeuroSpan-1)",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Auxilium Biotechnologies",
"sponsor_slug": "auxilium-biotechnologies",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06598189",
"publication_url": "https://clinicaltrials.gov/study/NCT06598189",
"title": "Real-time Seizure Detection, Classification, and Prediction Using a Low-Cost Low-Burden Ear-worn System",
"has_exemption": false,
"start_date": "2025-04-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Felicia Chu",
"sponsor_slug": "felicia-chu",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06746623",
"publication_url": "https://clinicaltrials.gov/study/NCT06746623",
"title": "Nonendoscopic Screening for Barrett's Esophagus and Esophageal Cancer in At-Risk Veterans Without History of Chronic Gastroesophageal Reflux",
"has_exemption": false,
"start_date": "2025-04-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Louis Stokes VA Medical Center",
"sponsor_slug": "louis-stokes-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06865105",
"publication_url": "https://clinicaltrials.gov/study/NCT06865105",
"title": "A Phase 2 Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects With Active Psoriatic Arthritis",
"has_exemption": false,
"start_date": "2025-04-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06364774",
"publication_url": "https://clinicaltrials.gov/study/NCT06364774",
"title": "Phase 1/2 Study Evaluating the Safety and Efficacy of Gene Therapy Employing Lentiviral Vector ALS20-transduced Hematopoietic Progenitor Cells in Subjects With Transfusion-dependent-thalassemia",
"has_exemption": false,
"start_date": "2025-04-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06499857",
"publication_url": "https://clinicaltrials.gov/study/NCT06499857",
"title": "Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation",
"has_exemption": false,
"start_date": "2025-04-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06761404",
"publication_url": "https://clinicaltrials.gov/study/NCT06761404",
"title": "Non-invasive VNS in Stroke Recovery",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06003166",
"publication_url": "https://clinicaltrials.gov/study/NCT06003166",
"title": "Pharmaco-Diagnostic Crossover Trial for Peripheral Nerve Continuity After Trauma",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arizona",
"sponsor_slug": "university-of-arizona",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05844501",
"publication_url": "https://clinicaltrials.gov/study/NCT05844501",
"title": "Inhibition of Small Conductance Calcium-Activated Potassium Current: A New Therapeutic Approach for Atrial Fibrillation",
"has_exemption": false,
"start_date": "2025-04-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06526299",
"publication_url": "https://clinicaltrials.gov/study/NCT06526299",
"title": "A Phase 2 Study of Biomarker-Modulated PSMA Theranostics",
"has_exemption": false,
"start_date": "2025-04-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06955728",
"publication_url": "https://clinicaltrials.gov/study/NCT06955728",
"title": "A Phase-IV Individually Randomized, Placebo-controlled Trial on Safety of RSVA/B-preF Vaccine in Pregnant Women and Efficacy Against Severe RSV-associated Lower Respiratory Tract Infection in Infants",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Witwatersrand, South Africa",
"sponsor_slug": "university-of-witwatersrand-south-africa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06325696",
"publication_url": "https://clinicaltrials.gov/study/NCT06325696",
"title": "Phase IIa Investigation of H01 in Adults With Interstitial Lung Disease (The SOLIS Study)",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Environmental Health Sciences (NIEHS)",
"sponsor_slug": "national-institute-of-environmental-health-sciences-niehs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06616584",
"publication_url": "https://clinicaltrials.gov/study/NCT06616584",
"title": "A Randomized Phase II/III Study of Docetaxel and Ramucirumab With or Without Cemiplimab for Participants Previously Treated With Platinum-Based Chemotherapy and Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Non-Matched Sub-Study)",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07039916",
"publication_url": "https://clinicaltrials.gov/study/NCT07039916",
"title": "A Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Assess the Efficacy and Safety of IMVT-1402 in Patients With Mild to Severe Generalized Myasthenia Gravis",
"has_exemption": false,
"start_date": "2025-05-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunovant Sciences GmbH",
"sponsor_slug": "immunovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07087106",
"publication_url": "https://clinicaltrials.gov/study/NCT07087106",
"title": "Novel Assessment of Glucose Consumption in Multiple Sclerosis Utilizing [F-18]FDG-PET",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06968689",
"publication_url": "https://clinicaltrials.gov/study/NCT06968689",
"title": "Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain - Phase II",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07004192",
"publication_url": "https://clinicaltrials.gov/study/NCT07004192",
"title": "The Role of hCG in Thawed Embryo Transfer",
"has_exemption": false,
"start_date": "2025-06-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fertility Center of Las Vegas",
"sponsor_slug": "fertility-center-of-las-vegas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06552169",
"publication_url": "https://clinicaltrials.gov/study/NCT06552169",
"title": "The RETIRE Trial: A Randomized Phase 2 Trial of Adoptive Therapy With Treg Adoptive Cell Transfer (TRACT) To Prevent Rejection in Living Donor Kidney Transplant Recipients",
"has_exemption": false,
"start_date": "2025-06-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Singulera Therapeutics Inc.",
"sponsor_slug": "singulera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06995898",
"publication_url": "https://clinicaltrials.gov/study/NCT06995898",
"title": "The Vanguard Study: Testing a New Way to Screen for Cancer",
"has_exemption": false,
"start_date": "2025-06-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06710119",
"publication_url": "https://clinicaltrials.gov/study/NCT06710119",
"title": "Effect of Custom Dynamic Orthoses on Forefoot Loading",
"has_exemption": false,
"start_date": "2025-06-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Iowa",
"sponsor_slug": "university-of-iowa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06138821",
"publication_url": "https://clinicaltrials.gov/study/NCT06138821",
"title": "Effect of Endoscopic Sleeve Gastroplasty on Patients With Obesity and Concomitant Metabolic Dysfunction-Associated Steatohepatitis (MASH): A Multicenter, Open-label, Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-06-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pichamol Jirapinyo, MD, MPH",
"sponsor_slug": "pichamol-jirapinyo-md-mph",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07009548",
"publication_url": "https://clinicaltrials.gov/study/NCT07009548",
"title": "CytoGam® as Adjuvant Therapy to Prevent or Attenuate Human Cytomegalovirus (CMV) Infection and Disease in Solid Organ Transplant Recipients",
"has_exemption": false,
"start_date": "2025-06-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fernanda P Silveira, MD, MS",
"sponsor_slug": "fernanda-p-silveira-md-ms",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06643260",
"publication_url": "https://clinicaltrials.gov/study/NCT06643260",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Daily Piclidenoson (CF101) Administered Orally in Subjects With Moderate-to-Severe Plaque Psoriasis",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Can-Fite BioPharma",
"sponsor_slug": "can-fite-biopharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06647524",
"publication_url": "https://clinicaltrials.gov/study/NCT06647524",
"title": "Pilot fMRI Studies of Aging-Related Effects of THC",
"has_exemption": false,
"start_date": "2025-07-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06999330",
"publication_url": "https://clinicaltrials.gov/study/NCT06999330",
"title": "Parcel-guided Transcranial Magnetic Stimulation for Anxiety in Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-07-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "HealthPartners Institute",
"sponsor_slug": "healthpartners-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298499",
"publication_url": "https://clinicaltrials.gov/study/NCT07298499",
"title": "Post-Market Clinical Follow-Up of Hearing Aids and Tinnitus Masker Technology",
"has_exemption": false,
"start_date": "2025-07-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Starkey Laboratories, Inc",
"sponsor_slug": "starkey-laboratories-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06757634",
"publication_url": "https://clinicaltrials.gov/study/NCT06757634",
"title": "VIKTORIA-2: A Randomized, Open-Label, Phase 3 Study of Fulvestrant and CDK4/6 Inhibitors With or Without Gedatolisib as First-Line Treatment in Patients With HR-Positive and HER2-Negative Advanced Breast Cancer",
"has_exemption": false,
"start_date": "2025-07-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Celcuity, Inc.",
"sponsor_slug": "celcuity-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07010159",
"publication_url": "https://clinicaltrials.gov/study/NCT07010159",
"title": "A Phase 2/3 Efficacy and Safety Study of KPL-387 Treatment in Participants With Recurrent Pericarditis",
"has_exemption": false,
"start_date": "2025-07-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kiniksa Pharmaceuticals International, plc",
"sponsor_slug": "kiniksa-pharmaceuticals-international-plc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07017673",
"publication_url": "https://clinicaltrials.gov/study/NCT07017673",
"title": "Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early Stage Triple Negative Breast Cancer",
"has_exemption": false,
"start_date": "2025-07-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07141329",
"publication_url": "https://clinicaltrials.gov/study/NCT07141329",
"title": "An Open-Label Extension, One-Year, Safety, and Efficacy Study of SPN-817 in Adults With Focal Onset Seizures",
"has_exemption": false,
"start_date": "2025-07-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Supernus Pharmaceuticals, Inc.",
"sponsor_slug": "supernus-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06047015",
"publication_url": "https://clinicaltrials.gov/study/NCT06047015",
"title": "Immune Response to Irreversible Electroporation (NanoKnife ®) and a Checkpoint Inhibitor With or Without CpG Oligodeoxynucleotides for the Treatment of Stage IV Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Saskatchewan",
"sponsor_slug": "university-of-saskatchewan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06557460",
"publication_url": "https://clinicaltrials.gov/study/NCT06557460",
"title": "A Phase IIb, Randomized, Assessor-Masked, Multicenter Clinical Trial to Assess the Safety and Efficacy of Subretinal Implantation of the CPCB-RPE1 Implant in Subjects With Advanced, Dry Age-Related Macular Degeneration (Geographic Atrophy) - PATCH AMD",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Regenerative Patch Technologies, LLC",
"sponsor_slug": "regenerative-patch-technologies-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06559995",
"publication_url": "https://clinicaltrials.gov/study/NCT06559995",
"title": "Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07089888",
"publication_url": "https://clinicaltrials.gov/study/NCT07089888",
"title": "A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Dotinurad Compared With Allopurinol in Adult Participants With Tophaceous Gout",
"has_exemption": false,
"start_date": "2025-08-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Crystalys Therapeutics",
"sponsor_slug": "crystalys-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06294574",
"publication_url": "https://clinicaltrials.gov/study/NCT06294574",
"title": "Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction",
"has_exemption": false,
"start_date": "2025-08-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06876363",
"publication_url": "https://clinicaltrials.gov/study/NCT06876363",
"title": "A Phase 1/2 Open-Label, Single-Ascending-Dose Study of EN-374, a Helper-Dependent Adenoviral-Based Gene Therapy, in Participants With X-Linked Chronic Granulomatous Disease",
"has_exemption": false,
"start_date": "2025-08-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ensoma",
"sponsor_slug": "ensoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07120295",
"publication_url": "https://clinicaltrials.gov/study/NCT07120295",
"title": "Prospective Multicenter Clinical Performance Study of a Single-use Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories",
"has_exemption": false,
"start_date": "2025-08-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06661915",
"publication_url": "https://clinicaltrials.gov/study/NCT06661915",
"title": "A Randomized Phase 2 Trial of ASTX727 +/- Iadademstat in Accelerated/Blast-Phase Philadelphia Chromosome-Negative Myeloproliferative Neoplasms (MPNs)",
"has_exemption": false,
"start_date": "2025-08-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06887192",
"publication_url": "https://clinicaltrials.gov/study/NCT06887192",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis",
"has_exemption": false,
"start_date": "2025-08-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "MapLight Therapeutics",
"sponsor_slug": "maplight-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07039526",
"publication_url": "https://clinicaltrials.gov/study/NCT07039526",
"title": "Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.",
"has_exemption": false,
"start_date": "2025-08-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "John Waters",
"sponsor_slug": "john-waters",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07145164",
"publication_url": "https://clinicaltrials.gov/study/NCT07145164",
"title": "Interleukin-15 to Promote Post-ART Control of HIV",
"has_exemption": false,
"start_date": "2025-08-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael Peluso, MD",
"sponsor_slug": "michael-peluso-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07147218",
"publication_url": "https://clinicaltrials.gov/study/NCT07147218",
"title": "Accelerated Transcranial Magnetic Stimulation for Major Depressive Disorder",
"has_exemption": false,
"start_date": "2025-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neuronetics",
"sponsor_slug": "neuronetics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07555210",
"publication_url": "https://clinicaltrials.gov/study/NCT07555210",
"title": "Pilot Study Assessment of Bone Mineral Density Changes During Treatment With Anti-PD-1 Immunotherapy Agents",
"has_exemption": false,
"start_date": "2025-08-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessica Mezzanotte Sharpe",
"sponsor_slug": "jessica-mezzanotte-sharpe",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07138859",
"publication_url": "https://clinicaltrials.gov/study/NCT07138859",
"title": "Prospective, Multiceter, Randomized, Controlled Study on the Intraoperative Technical Errors of Robotic vs. Laparoscopic Radical Right Hemiclectomy (Superiority Design，ROBOGEON® 2501study)",
"has_exemption": false,
"start_date": "2025-08-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Affiliated Hospital of Qingdao University",
"sponsor_slug": "the-affiliated-hospital-of-qingdao-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06528769",
"publication_url": "https://clinicaltrials.gov/study/NCT06528769",
"title": "A Phase II Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma",
"has_exemption": false,
"start_date": "2025-09-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gabriel Tinoco",
"sponsor_slug": "gabriel-tinoco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06751602",
"publication_url": "https://clinicaltrials.gov/study/NCT06751602",
"title": "A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Belumosudil for the Abrogation of Interstitial Fibrosis and Tubular Atrophy in de Novo Kidney Transplant Recipients",
"has_exemption": false,
"start_date": "2025-09-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06752694",
"publication_url": "https://clinicaltrials.gov/study/NCT06752694",
"title": "Ruxolitinib Based GVHD Prophylaxis Regimen for Older Adults Receiving Non-ATG Containing Non-Myeloablative Hematopoietic Cell Transplantation for Acquired Aplastic Anemia",
"has_exemption": false,
"start_date": "2025-09-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04589065",
"publication_url": "https://clinicaltrials.gov/study/NCT04589065",
"title": "Pilot Study to Assess the Safety and Efficacy of a Selective Cytopheretic Device (SCD) to Treat Patients With NYHA Stage III or IV Heart Failure (HF) With Persistent Congestion and Worsening Renal Function as a Result of Cardiorenal Syndrome (CRS) That is Resistant to Optimal Medical Therapy Including Loop Diuretics",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lenar Yessayan",
"sponsor_slug": "lenar-yessayan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06040476",
"publication_url": "https://clinicaltrials.gov/study/NCT06040476",
"title": "A Phase II, Randomized, Double-blind, Parallel, Placebo-controlled Study to Assess the Safety and Efficacy of Human Umbilical Cord Blood Infusion in Patients with Acute Ischemic Stroke",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "StemCyte, Inc.",
"sponsor_slug": "stemcyte-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06620692",
"publication_url": "https://clinicaltrials.gov/study/NCT06620692",
"title": "A Phase IIa Study to Investigate the Efficacy and Safety Profile of GM-XANTHO [GM-XAN003] in Patients with Psoriasis",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Xantho Biotechnology Co., LTD",
"sponsor_slug": "xantho-biotechnology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07162259",
"publication_url": "https://clinicaltrials.gov/study/NCT07162259",
"title": "Real-world Cohort Study on Sequential Therapy With ADC Drugs Following Progression of Endocrine Therapy Guided by Molecular Biomarkers in HR-positive/HER2-negative Advanced Breast Cancer",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yan Xue",
"sponsor_slug": "yan-xue",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214142",
"publication_url": "https://clinicaltrials.gov/study/NCT07214142",
"title": "Efficacy and Safety of Total Neoadjuvant Chemoradiotherapy Combined With PD-1 Therapy for Locally Advanced Rectal Cancer With High Risk of Recurrence",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The First Affiliated Hospital of University of Science and Technology of China",
"sponsor_slug": "the-first-affiliated-hospital-of-university-of-science-and-technology-of-china",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07362095",
"publication_url": "https://clinicaltrials.gov/study/NCT07362095",
"title": "An Exploratory Study on the Safety and Efficacy of Luspatercept in the Treatment of Anemia Following Allogeneic Hematopoietic Stem Cell Transplantation for Acute Leukemia",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zhujiang Hospital",
"sponsor_slug": "zhujiang-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07353918",
"publication_url": "https://clinicaltrials.gov/study/NCT07353918",
"title": "Neuromodulation Using Low-intensity Focused Ultrasound for Potential Treatment for Medically Refractory Temporal Lobe Epilepsy",
"has_exemption": false,
"start_date": "2025-10-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Carilion Clinic",
"sponsor_slug": "carilion-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07188090",
"publication_url": "https://clinicaltrials.gov/study/NCT07188090",
"title": "A Prospective Trial Evaluating Plerixafor-based Mobilization and Risk of Engraftment Syndrome After Autologous Hematopoietic Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2025-10-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Jefferson University",
"sponsor_slug": "thomas-jefferson-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06116838",
"publication_url": "https://clinicaltrials.gov/study/NCT06116838",
"title": "Effect of Varying Transcutaneous Spinal Cord Stimulation Parameters and Location on Lower Extremity Motor Responses and Comfort",
"has_exemption": false,
"start_date": "2025-10-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shirley Ryan AbilityLab",
"sponsor_slug": "shirley-ryan-abilitylab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06810934",
"publication_url": "https://clinicaltrials.gov/study/NCT06810934",
"title": "A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses",
"has_exemption": false,
"start_date": "2025-10-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kara Chew",
"sponsor_slug": "kara-chew",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07194265",
"publication_url": "https://clinicaltrials.gov/study/NCT07194265",
"title": "A Prospective Randomized Trial Assessing the Safety and Effectiveness of the DurAVR® Biomimetic Valve Designed for Physiologic Flow Compared to Commercial TAVR Devices",
"has_exemption": false,
"start_date": "2025-10-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Anteris Technologies Ltd.",
"sponsor_slug": "anteris-technologies-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06631638",
"publication_url": "https://clinicaltrials.gov/study/NCT06631638",
"title": "Planned vs. Actual Acetabular Cup Position in Total Hip Arthroplasty With Non-Invasive Navigation",
"has_exemption": false,
"start_date": "2025-10-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy Orthopaedics",
"sponsor_slug": "depuy-orthopaedics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06992258",
"publication_url": "https://clinicaltrials.gov/study/NCT06992258",
"title": "A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Criterium, Inc.",
"sponsor_slug": "criterium-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06820957",
"publication_url": "https://clinicaltrials.gov/study/NCT06820957",
"title": "Randomized Phase 2/3 Trial of Vincristine-Irinotecan-Regorafenib in Combination With Vincristine-Doxorubicin-Cyclophosphamide (VDC) and Ifosfamide-Etoposide (IE) in Patients With Newly Diagnosed Metastatic Ewing Sarcoma",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07154693",
"publication_url": "https://clinicaltrials.gov/study/NCT07154693",
"title": "Wound Healing Following Tooth Extraction and Ridge Preservation Using Resorbable Non-ceramic Calcium Apatite Granules in Type I Bovine Collagen Plugs (OsteoGen®)",
"has_exemption": false,
"start_date": "2025-11-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07189065",
"publication_url": "https://clinicaltrials.gov/study/NCT07189065",
"title": "An Open-Label, Randomized Controlled, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of Rocbrutinib Monotherapy Versus Investigator's Choice of Therapy in Patients With Relapsed or Refractory Non-GCB Diffuse Large B-Cell Lymphoma",
"has_exemption": false,
"start_date": "2025-11-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Guangzhou Lupeng Pharmaceutical Company LTD.",
"sponsor_slug": "guangzhou-lupeng-pharmaceutical-company-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07296484",
"publication_url": "https://clinicaltrials.gov/study/NCT07296484",
"title": "Clofutriben And Placebo Phase 2 Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)",
"has_exemption": false,
"start_date": "2025-11-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sparrow Pharmaceuticals",
"sponsor_slug": "sparrow-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221721",
"publication_url": "https://clinicaltrials.gov/study/NCT07221721",
"title": "A Pilot Study to Assess the Feasibility and Safety of Targeting Mean Arterial Pressure to Reduce Intra-operative Hypotension",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bradley Marino",
"sponsor_slug": "bradley-marino",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225244",
"publication_url": "https://clinicaltrials.gov/study/NCT07225244",
"title": "Comparative Outcomes of Four Versus Two Balloon Inflation Points in Dacryoplasty for Primary Acquired Nasolacrimal Duct Obstruction",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Taiwan University Hospital",
"sponsor_slug": "national-taiwan-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06771830",
"publication_url": "https://clinicaltrials.gov/study/NCT06771830",
"title": "A Rapid Diagnostic of Risk in Hospitalized Pediatric Patients to Improve Outcomes Using Machine Learning",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06820281",
"publication_url": "https://clinicaltrials.gov/study/NCT06820281",
"title": "Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes: a Phase 2 Double Blinded Placebo Controlled Clinical Trial (TIRTLE2)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Garvan Institute of Medical Research",
"sponsor_slug": "garvan-institute-of-medical-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07137104",
"publication_url": "https://clinicaltrials.gov/study/NCT07137104",
"title": "A Phase I/IIa Study to Investigate the Safety, Tolerability, and Preliminary Effectiveness of HeXell-2020 in Patients With Stable Coronary Artery Disease (CAD)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hexun Biosciences Co., LTD.",
"sponsor_slug": "hexun-biosciences-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07249931",
"publication_url": "https://clinicaltrials.gov/study/NCT07249931",
"title": "Efficacy and Safety of Nerivio for the Management of Amplified Musculoskeletal Pain Syndrome in Pediatric Patients: A Nurse Practitioner-Led Pilot Study",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Health",
"sponsor_slug": "childrens-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174687",
"publication_url": "https://clinicaltrials.gov/study/NCT07174687",
"title": "Efficacy of Dapagliflozin in the Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2025-12-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06666608",
"publication_url": "https://clinicaltrials.gov/study/NCT06666608",
"title": "The Efficacy of Bone Stimulator in Treatment and Return-to-Sport for Spondylolysis",
"has_exemption": false,
"start_date": "2025-12-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07283835",
"publication_url": "https://clinicaltrials.gov/study/NCT07283835",
"title": "A Single-arm, Open-label, Multicenter Phase II Clinical Study to Evaluate the Efficacy and Safety of Cretostimogene Grenadenorepvec in Patients With BCG-unresponsive High-risk Non-Muscle Invasive Bladder Cancer",
"has_exemption": false,
"start_date": "2025-12-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lepu Biopharma Co., Ltd.",
"sponsor_slug": "lepu-biopharma-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04792034",
"publication_url": "https://clinicaltrials.gov/study/NCT04792034",
"title": "An Open-label, Two-Arm, Pharmacokinetics, Safety, and Tolerability Study of a Single Topical Dose of GOPRELTO® Nasal Solution and a Single Dose of NUMBRINO™ Nasal Solution for the Induction of Local Anesthesia of the Mucous Membranes When Performing Diagnostic Procedures and Surgeries in Pediatric Subjects From ≥12 Years to <18 Years of Age",
"has_exemption": false,
"start_date": "2025-12-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Noden Pharma",
"sponsor_slug": "noden-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06946550",
"publication_url": "https://clinicaltrials.gov/study/NCT06946550",
"title": "1470 nm Non-Ablative Laser for the Treatment of Scarring Alopecia: A Clinical and Mechanistic Study",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07007559",
"publication_url": "https://clinicaltrials.gov/study/NCT07007559",
"title": "Protocol ASPEN-09-03: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Participants With Metastatic HER2-Positive Breast Cancer, a Substudy Under Master Protocol ASPEN-09: A Phase 1b/2, Multicenter, Multi Arm Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies",
"has_exemption": false,
"start_date": "2025-12-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ALX Oncology Inc.",
"sponsor_slug": "alx-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07322094",
"publication_url": "https://clinicaltrials.gov/study/NCT07322094",
"title": "CATALINA-4: Phase 1B/2 Study of TORL-1-23 With Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Newly Diagnosed Patients With Advanced Stage Ovarian Cancer",
"has_exemption": false,
"start_date": "2025-12-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "TORL Biotherapeutics, LLC",
"sponsor_slug": "torl-biotherapeutics-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07217717",
"publication_url": "https://clinicaltrials.gov/study/NCT07217717",
"title": "A Phase 3, Multicenter, Prospective Open-Label Study of the Diagnostic Performance of [¹⁸F]FAPI-74 PET/CT for the Detection of Metastatic Disease in Adults With Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-12-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SOFIE",
"sponsor_slug": "sofie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215845",
"publication_url": "https://clinicaltrials.gov/study/NCT07215845",
"title": "Pars Healing on oZTEo MRI",
"has_exemption": false,
"start_date": "2025-12-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Missouri-Columbia",
"sponsor_slug": "university-of-missouri-columbia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07280260",
"publication_url": "https://clinicaltrials.gov/study/NCT07280260",
"title": "Effects of Early Loading Protocol on the Survival of the Nobel N1 Implant System: A Pilot Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Louisiana State University Health Sciences Center in New Orleans",
"sponsor_slug": "louisiana-state-university-health-sciences-center-in-new-orleans",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07280156",
"publication_url": "https://clinicaltrials.gov/study/NCT07280156",
"title": "A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study Assessing the Efficacy, Safety, and Dosing Regimen Selection of Multiple Intravenous Infusions of PRX-115 With and Without Methotrexate Versus Placebo in Adult Patients With Gout (RELEASE)",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Protalix",
"sponsor_slug": "protalix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07447050",
"publication_url": "https://clinicaltrials.gov/study/NCT07447050",
"title": "RiluzolE FOr Preventing Cognitive DysfUnction in Cancer PatientS Receiving Chemotherapy (REFOCUS)",
"has_exemption": false,
"start_date": "2025-12-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07386340",
"publication_url": "https://clinicaltrials.gov/study/NCT07386340",
"title": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature",
"has_exemption": false,
"start_date": "2025-12-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Senseonics, Inc.",
"sponsor_slug": "senseonics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07264894",
"publication_url": "https://clinicaltrials.gov/study/NCT07264894",
"title": "ZSDT for the Treatment of Recurrent Refractory Mantle Cell Lymphoma After BTK Inhibitor Failure: a Multi-center Prospective Clinical Trial",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zhengzhou University",
"sponsor_slug": "zhengzhou-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07282678",
"publication_url": "https://clinicaltrials.gov/study/NCT07282678",
"title": "Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder: Double-Blind, Controlled Randomized Multicenter Clinical Trial",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pulvinar Neuro, LLC",
"sponsor_slug": "pulvinar-neuro-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06895889",
"publication_url": "https://clinicaltrials.gov/study/NCT06895889",
"title": "A Prospective, Randomized, Controlled, Open-label, First-in-human Phase I/IIb Study to Evaluate the Safety and Efficacy of the EB-OC Graft in the Repair of Full Thickness Chondral/osteochondral Defects of the Knee",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Epibone, Inc.",
"sponsor_slug": "epibone-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07180576",
"publication_url": "https://clinicaltrials.gov/study/NCT07180576",
"title": "The FORCE Trial Pilot",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Anna Arthur, PhD",
"sponsor_slug": "anna-arthur-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07513493",
"publication_url": "https://clinicaltrials.gov/study/NCT07513493",
"title": "The Conventional Pipelle vs the Curved Aspirator Device: a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-01-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Maimonides Medical Center",
"sponsor_slug": "maimonides-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07476560",
"publication_url": "https://clinicaltrials.gov/study/NCT07476560",
"title": "Mesh Matters: Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment - a Randomized, Blinded Multicenter Study",
"has_exemption": false,
"start_date": "2026-01-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Regionshospital Nordjylland",
"sponsor_slug": "regionshospital-nordjylland",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06904261",
"publication_url": "https://clinicaltrials.gov/study/NCT06904261",
"title": "An Open-label Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of 12 Month Treatment With Migalastat in Pediatric Subjects (Aged 2 to < 12 Years) With Fabry Disease and Amenable GLA Variants",
"has_exemption": false,
"start_date": "2026-01-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Amicus Therapeutics",
"sponsor_slug": "amicus-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158775",
"publication_url": "https://clinicaltrials.gov/study/NCT07158775",
"title": "A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01, a Recombinant Adeno-Associated Virus Vector Expressing ChronosFP (AAV2-CAGChronosFP) in Patients With Geographic Atrophy Secondary to Dry AMD",
"has_exemption": false,
"start_date": "2026-01-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bionic Sight LLC",
"sponsor_slug": "bionic-sight-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219576",
"publication_url": "https://clinicaltrials.gov/study/NCT07219576",
"title": "PRISM: Phase 1b of Retifanlimab and Ruxolitinib In Solid Malignancies Progressing on Prior Checkpoint Inhibition",
"has_exemption": false,
"start_date": "2026-01-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07089121",
"publication_url": "https://clinicaltrials.gov/study/NCT07089121",
"title": "Descartes-08 for Children, Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus, ANCA-associated Vasculitis, Juvenile Myasthenia Gravis, and Juvenile Dermatomyositis",
"has_exemption": false,
"start_date": "2026-01-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cartesian Therapeutics",
"sponsor_slug": "cartesian-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07196462",
"publication_url": "https://clinicaltrials.gov/study/NCT07196462",
"title": "Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia",
"has_exemption": false,
"start_date": "2026-01-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07418112",
"publication_url": "https://clinicaltrials.gov/study/NCT07418112",
"title": "Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-01-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225621",
"publication_url": "https://clinicaltrials.gov/study/NCT07225621",
"title": "Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial Comparing Standard of Care Adjuvant Temozolomide With or Without 5-Aminolevulinic Acid (5-ALA) With Concomitant Low Intensity Diffuse Ultrasound (LIDU) Sonodynamic Therapy (SDT) System In Patients With Newly Diagnosed Glioblastoma After Completion of Chemoradiotherapy",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alpheus Medical, Inc.",
"sponsor_slug": "alpheus-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07323654",
"publication_url": "https://clinicaltrials.gov/study/NCT07323654",
"title": "A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Dose-ranging Study Investigating the Efficacy and Safety Profile of KT-621 Administered Orally to Adult Participants With Uncontrolled Moderate to Severe Eosinophilic Asthma",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kymera Therapeutics, Inc.",
"sponsor_slug": "kymera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07290790",
"publication_url": "https://clinicaltrials.gov/study/NCT07290790",
"title": "A Prospective, Multicenter, Randomized, Post-market Clinical Investigation to Assess the Accuracy of Different Tooth Movements for Patients Undergoing Clear Aligner Therapy (CAT) With SureSmile® Clear Aligners With Three Different Trimlines.",
"has_exemption": false,
"start_date": "2026-01-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dentsply Sirona Implants and Consumables",
"sponsor_slug": "dentsply-sirona-implants-and-consumables",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07415941",
"publication_url": "https://clinicaltrials.gov/study/NCT07415941",
"title": "Home-based Mindfulness-based Meditation and Transcutaneous Auricular Vagus Nerve Stimulation for Older Adults With Low Back Pain and Depressive Symptoms",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Florida State University",
"sponsor_slug": "florida-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06950281",
"publication_url": "https://clinicaltrials.gov/study/NCT06950281",
"title": "Low Sodium Oxybate Use for Nocturnal Cluster Headache: Safety, Efficacy and Tolerability of JZP-258 (XYWAV) - a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Bi-center Study.",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Leiden University Medical Center",
"sponsor_slug": "leiden-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07231237",
"publication_url": "https://clinicaltrials.gov/study/NCT07231237",
"title": "A Multi-site, Single-Arm Clinical Study Evaluating the Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure Due to Trauma, Deep Caries, or Mechanical Etiology Under Dental Restorations",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Solventum US LLC",
"sponsor_slug": "solventum-us-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07335510",
"publication_url": "https://clinicaltrials.gov/study/NCT07335510",
"title": "Impact of Barostimulation in Cardiac Hemodynamics and Clinical Outcomes Through Use of the Barostim™ CVRx Device",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07426120",
"publication_url": "https://clinicaltrials.gov/study/NCT07426120",
"title": "A Double-blind, Randomized, Placebo-controlled, Parallel-controlled, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of a Botanical Total Coumarin Cream (TC Cream) in Treating Patients With Psoriasis Vulgaris",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Psoriasis Research Institute of Guangzhou",
"sponsor_slug": "psoriasis-research-institute-of-guangzhou",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07348640",
"publication_url": "https://clinicaltrials.gov/study/NCT07348640",
"title": "A Prospective, Multi-National, Randomized, Double-Blind, Crossover Study to Evaluate the Efficacy and Safety of Gadopiclenol-enhanced MRA Compared to Gadoterate Meglumine-enhanced MRA in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Guerbet",
"sponsor_slug": "guerbet",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07250750",
"publication_url": "https://clinicaltrials.gov/study/NCT07250750",
"title": "A Phase 1b/2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Investigate A) the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of IM-101 in Adult Participants With Generalized Myasthenia Gravis, and B) the Efficacy and Safety of Treatment of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis",
"has_exemption": false,
"start_date": "2026-02-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ImmunAbs Inc.",
"sponsor_slug": "immunabs-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07195071",
"publication_url": "https://clinicaltrials.gov/study/NCT07195071",
"title": "Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening",
"has_exemption": false,
"start_date": "2026-02-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07189871",
"publication_url": "https://clinicaltrials.gov/study/NCT07189871",
"title": "A Phase 1/2a Study of the Safety, Tolerability, and Preliminary Clinical Activity of 177LuBetaBart, a 177Lu-Labeled Anti-B7-H3 Monoclonal Antibody, in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-02-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Radiopharm Theranostics, Ltd",
"sponsor_slug": "radiopharm-theranostics-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07500012",
"publication_url": "https://clinicaltrials.gov/study/NCT07500012",
"title": "Home-based Pain and Symptom Management for Breast Cancer Survivors: a Triple- Blinded RCT Pilot Study of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
"has_exemption": false,
"start_date": "2026-02-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Florida State University",
"sponsor_slug": "florida-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06502691",
"publication_url": "https://clinicaltrials.gov/study/NCT06502691",
"title": "[18F]FTT Positron Emission Tomography (PET) in Patients With Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07474519",
"publication_url": "https://clinicaltrials.gov/study/NCT07474519",
"title": "An Assessment of Patient Position and Intravesical BCG Dwell Time",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University Comprehensive Cancer Center",
"sponsor_slug": "ohio-state-university-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07111988",
"publication_url": "https://clinicaltrials.gov/study/NCT07111988",
"title": "Valbenazine in Obsessive-compulsive Disorder: A Randomized Double-blind Placebo-controlled Crossover Trial",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07139405",
"publication_url": "https://clinicaltrials.gov/study/NCT07139405",
"title": "A DOUBLE-BLIND, RANDOMIZED, ACTIVE-CONTROLLED, PARALLEL-GROUP, PHASE II TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND SUPERIORITY OF TRIGLYTZA® OVER METFORMIN IN PATIENTS WITH INADEQUATE GLYCEMIC CONTROL OVER 24 WEEKS OF TREATMENT",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Myopharm Limited",
"sponsor_slug": "myopharm-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226089",
"publication_url": "https://clinicaltrials.gov/study/NCT07226089",
"title": "Multicenter Interventional Study: Somatrogon Impact on Outcomes in Naive Small for Gestational Age or Idiopathic Short Stature Pediatric Patients Compared With Daily Growth Hormone",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rabin Medical Center",
"sponsor_slug": "rabin-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07231965",
"publication_url": "https://clinicaltrials.gov/study/NCT07231965",
"title": "Effects Of Cannabis Products On Blood Pressure Control",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07369128",
"publication_url": "https://clinicaltrials.gov/study/NCT07369128",
"title": "A Randomized, Dose-Ranging Trial of Propofol-Only and Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07388355",
"publication_url": "https://clinicaltrials.gov/study/NCT07388355",
"title": "WearLinq eWave Patch Study",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wearlinq",
"sponsor_slug": "wearlinq",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221708",
"publication_url": "https://clinicaltrials.gov/study/NCT07221708",
"title": "Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin in Patients Treated With Systemic Antibiotic Therapy in a Community Hospital",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07301424",
"publication_url": "https://clinicaltrials.gov/study/NCT07301424",
"title": "Phase II Study of Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL Positive B-Cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alberta",
"sponsor_slug": "university-of-alberta",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325591",
"publication_url": "https://clinicaltrials.gov/study/NCT07325591",
"title": "A Phase 2B/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Tazbentetol in Participants With Amyotrophic Lateral Sclerosis (ALS)",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Spinogenix",
"sponsor_slug": "spinogenix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07454915",
"publication_url": "https://clinicaltrials.gov/study/NCT07454915",
"title": "PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PapiVax Biotech, Inc.",
"sponsor_slug": "papivax-biotech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07437339",
"publication_url": "https://clinicaltrials.gov/study/NCT07437339",
"title": "Volume Reduction for Open Fracture Irrigation: A Randomized Prospective Feasibility Trial",
"has_exemption": false,
"start_date": "2026-03-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Inova Health Care Services",
"sponsor_slug": "inova-health-care-services",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}