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"title": "A Phase I/II Multicenter Study Combining Guadecitabine, a DNA Methyltransferase Inhibitor, With Atezolizumab, an Immune Checkpoint Inhibitor, in Patients With Intermediate or High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia",
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"title": "18F-Fluoro-L- DOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism",
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"title": "Phase I/IIa Trial Evaluating Safety of LOAd703, an Armed Oncolytic Adenovirus for Pancreatic Cancer",
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"title": "Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia",
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"title": "MATCH Treatment Subprotocol Z1I: Phase II Study of AZD1775 in Patients With Tumors Containing BRCA1 and BRCA2 Mutations",
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"title": "A Phase 2, Multicenter Study to Evaluate the Efficacy and Safety Using Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients With Recurrent, Metastatic or Persistent Cervical Carcinoma",
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"title": "Phase II Randomized Double Blind Trial of PF-04518600, an OX40 Antibody, in Combination With Axitinib Versus Axitinib in Immune-Checkpoint Inhibitor Exposed Patients With Metastatic Renal Cell Carcinoma",
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"title": "Phase I/II Study of Sorafenib Added to Busulfan and Fludarabine Conditioning Regimen in Patients With Relapsed/Refractory AML Undergoing Stem Cell Transplantation",
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"title": "A Phase I/II Study of Blinatumomab in Combination With Pembrolizumab (MK-3475) for Adults With Relapsed or Refractory B-lineage Acute Lymphoblastic Leukemia With High Bone Marrow Lymphoblast Percentage",
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"title": "A Phase II Study of Triple Combination of Atezolizumab + Cobimetinib + Eribulin (ACE) or Atezolizumab + Eribulin (AE) in Patients With Recurrent/Metastatic Inflammatory Breast Cancer",
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"title": "A Prospective Randomized Controlled Trial of Electroconvulsive Therapy with Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine with Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial",
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"title": "An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors",
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"title": "Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma",
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"start_date": "2017-09-22",
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"title": "A Phase II Study of Preoperative Pembrolizumab for Mismatch-Repair Deficient and Epstein-Barr Virus Positive Gastric Cancer Followed by Chemotherapy and Chemoradiation With Pembrolizumab",
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"start_date": "2017-09-29",
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"registry_id": "NCT03216005",
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"title": "Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System",
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"start_date": "2017-11-02",
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"registry_id": "NCT03317158",
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"title": "PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-Unresponsive, BCG-RelaPsing, and High-Risk BCG-Naive Non-muscle Invasive UroThelial Carcinoma of the BLADDER",
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"start_date": "2017-11-21",
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"title": "A Phase III, Double-Blinded, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Neoadjuvant Treatment With Atezolizumab or Placebo in Combination With Platinum-Based Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer",
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"title": "Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Atrophic Dry Age Related Macular Degeneration",
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"start_date": "2018-04-26",
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"title": "Phase I/II, Open-Label Study Evaluating the Efficacy and Pharmacokinetics of Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Neoplasms During Neurosurgical Procedures",
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"title": "An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With REGN2810 in Subjects With Newly-Diagnosed Glioblastoma (GBM)",
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"start_date": "2018-05-31",
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"registry_id": "NCT03150511",
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"title": "Tesamorelin Therapy to Enhance Axonal Regeneration, Minimize Muscle Atrophy, and Improve Functional Outcomes Following Peripheral Nerve Injury",
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"start_date": "2018-06-01",
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"registry_id": "NCT03490929",
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"title": "Contrast Enhanced Ultrasonography for Blunt Abdominal Trauma Imaging in Children",
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"start_date": "2018-06-01",
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"registry_id": "NCT03230565",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03230565",
"title": "A Prospective Comparison of Pain and Analgesia in Patients With Continuous Peripheral Nerve Block Catheters Using Continuous Infusion or Scheduled Bolus Infusion",
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"start_date": "2018-06-01",
"completion_date": "2025-12-31",
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{
"registry_id": "NCT03491761",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03491761",
"title": "Does Intra-articular Platelet-Rich Plasma Injection Provide Superior Outcomes Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis?",
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"start_date": "2018-06-13",
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"title": "A Combination Therapy for Cancer-Related Fatigue in Advanced Cancer Patients",
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"start_date": "2018-06-29",
"completion_date": "2025-12-31",
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"registry_id": "NCT02298504",
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"title": "Evaluation of MTA Pulpotomy, Biodentine Pulpotomy, and Glass Ionomer Indirect Pulp Treatment in Primary Teeth",
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"start_date": "2018-07-01",
"completion_date": "2025-12-31",
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"sponsor_name": "University of Maryland, Baltimore",
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{
"registry_id": "NCT03565783",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03565783",
"title": "Phase II Study of REGN2810 Prior to Surgery in Patients With Stage II-IV Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck",
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"start_date": "2018-07-03",
"completion_date": "2025-12-31",
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{
"registry_id": "NCT03233711",
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"title": "A Randomized Phase III Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer",
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"start_date": "2018-07-05",
"completion_date": "2025-12-31",
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"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Ralinepag When Added to PAH Standard of Care or PAH Specific Background Therapy in Subjects With WHO Group 1 PAH",
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"title": "Closed Loop Deep Brain Stimulation in Parkinson's Disease and Dystonia (Activa RC+S)",
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"start_date": "2018-10-01",
"completion_date": "2025-12-31",
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"title": "Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy in the Management of Gleason Group 5 Prostate Cancer",
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"start_date": "2018-10-03",
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{
"registry_id": "NCT03729518",
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"title": "A Phase II Study of Volume and Dose De-Intensification Following Transoral Robotic Surgery (TORS) and Neck Dissection for p16+ Oropharyngeal Squamous Cell Carcinoma",
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"start_date": "2018-10-11",
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{
"registry_id": "NCT03668340",
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"title": "A Phase 2 Study of the Wee1 Inhibitor AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma",
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"start_date": "2018-10-22",
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{
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"title": "PRE-ProstAtectomy MRI-GuidEd Stereotactic Body RadioTherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT)",
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{
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"title": "The Effects of Combination Therapy of Opioids Versus Non-Opioids on Postoperative Pain Management After Knee Arthroscopic Surgery: A Prospective Randomized Controlled Study",
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"start_date": "2018-10-29",
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{
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"title": "A Pilot Study in the Treatment of Refractory Adenovirus (ADV) Infection With Related Donor ADV Cytotoxic T-Lymphocytes (ADV-CTLs)in Children, Adolescents and Young Adult Recipients",
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"start_date": "2018-11-01",
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"registry_id": "NCT03266640",
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"title": "A Pilot Study in the Treatment of Refractory Cytomegalovirus (CMV) Infections With Related Donor CMV Specific Cytotoxic T-cells (CTLs) in Children, Adolescents and Young Adult Recipients",
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"start_date": "2018-11-01",
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{
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"title": "Open Label Extension Study to Evaluate the Long-term Safety and Efficacy of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Administered by Intravenous Infusion Every 4 Weeks in Adult Patients With Fabry Disease",
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{
"registry_id": "NCT03634241",
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"title": "Single-Arm, Phase II of Immunotherapy With Pembrolizumab for the Prevention of Lung Cancer (IMPRINT-Lung)",
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"start_date": "2018-11-13",
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{
"registry_id": "NCT03712605",
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"title": "STAMP: Surgically Treated Adjuvant Merkel Cell Carcinoma With Pembrolizumab, a Phase III Trial",
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"start_date": "2018-11-15",
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{
"registry_id": "NCT03747146",
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"title": "Expanding the Peri-operative Surgical Home Model: ERAS TKR With a Transitional Pain Service (TeleTPS)- Continuous Adductor Canal Catheter Versus Adductor Canal Block for Total Knee Arthroplasty, a Randomized Double-blind Controlled Trial",
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"start_date": "2018-11-16",
"completion_date": "2025-12-31",
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"sponsor_name": "Hospital for Special Surgery, New York",
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{
"registry_id": "NCT02905578",
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"title": "A Phase II Trial of Pharmacological Ascorbate, Gemcitabine, and Nab-Paclitaxel for Metastatic Pancreatic Cancer (PACMAN 2.1)",
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"start_date": "2018-11-28",
"completion_date": "2025-12-31",
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{
"registry_id": "NCT03586336",
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"title": "Remote Dielectric Sensing Technology Guided Diuresis in Hospitalized Patients With Acute Decompensated Heart Failure",
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"start_date": "2018-12-01",
"completion_date": "2025-12-31",
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"sponsor_name": "University of California, San Francisco",
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{
"registry_id": "NCT03792919",
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"title": "Virological Response After Cessation of Long Term Anti-HBV Nucleos(t)Ide Analogues (NAs) vs. Keeping on NAs Among Chronic Hepatitis B (CHB) Patients",
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"start_date": "2018-12-01",
"completion_date": "2025-12-31",
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"title": "Outcomes Mandate National Integration With Cannabis as Medicine",
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"start_date": "2018-12-01",
"completion_date": "2025-12-31",
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"sponsor_name": "OMNI Medical Services, LLC",
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{
"registry_id": "NCT03670056",
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"title": "A Pilot Study of Combination Immunotherapy With Ipilimumab and Nivolumab in Patients With Recurrent Extensive Stage Small Cell Lung Cancer (SCLC) Who Have Previously Received Platinum-based Chemotherapy",
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"start_date": "2018-12-06",
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"sponsor_name": "Yale University",
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"days_late": null
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{
"registry_id": "NCT03579316",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03579316",
"title": "EFFORT: Efficacy of AZD1775 in Parp Resistance; A Randomized 2-Arm, Non-Comparative Phase 2 Study of AZD1775 Alone or AZD1775 and Olaparib in Women With Ovarian Cancer Who Have Progressed During PARP Inhibition",
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"start_date": "2018-12-07",
"completion_date": "2025-12-31",
"has_results": false,
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"sponsor_name": "M.D. Anderson Cancer Center",
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{
"registry_id": "NCT03995628",
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"title": "Randomized, Controlled Trial of Post-operative Steroids and Pain Control After Tonsillectomy",
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"start_date": "2018-12-18",
"completion_date": "2025-12-31",
"has_results": false,
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"sponsor_name": "Medical University of South Carolina",
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"days_late": null
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{
"registry_id": "NCT03559049",
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"title": "A Phase I/II Multi-site Study of Rucaparib and Pembrolizumab Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer After Initial Therapy With Carboplatin, Pemetrexed, and Pembrolizumab",
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"start_date": "2018-12-24",
"completion_date": "2025-12-31",
"has_results": false,
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"sponsor_name": "University of Michigan Rogel Cancer Center",
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{
"registry_id": "NCT03711032",
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"title": "A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) That is Either Persistent or Recurrent Following BCG Induction or That is Naïve to BCG Treatment (KEYNOTE-676)",
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"start_date": "2018-12-24",
"completion_date": "2025-12-31",
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{
"registry_id": "NCT04092192",
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"title": "Prospective Comparison of Rigid Forceps Versus Endovascular Snare for Routine IVC Filter Retrieval",
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"start_date": "2018-12-26",
"completion_date": "2025-12-31",
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"sponsor_name": "University of Chicago",
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{
"registry_id": "NCT03793140",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03793140",
"title": "A Phase II Clinical Trial of CPI-613 in Patients With Relapsed or Refractory Burkitt Lymphoma/Leukemia or High-grade B-cell Lymphoma With Rearrangements of MYC and BCL2 and/or BCL6",
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"start_date": "2018-12-31",
"completion_date": "2025-12-31",
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"sponsor_name": "Memorial Sloan Kettering Cancer Center",
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{
"registry_id": "NCT03574207",
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"title": "Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities",
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"start_date": "2019-01-01",
"completion_date": "2025-12-31",
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{
"registry_id": "NCT03749018",
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"title": "A Phase II Study of Nivolumab in Combination With DA-REPOCH Followed by Short Course Nivolumab Consolidation in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma",
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"start_date": "2019-01-02",
"completion_date": "2025-12-31",
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"days_late": null
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{
"registry_id": "NCT03587701",
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"title": "A Phase II Placebo Controlled Study of the Effects of Anakinra (Kineret) in Subjects With Corticosteroid-Resistant/Intolerant Meniere's Disease (CR-MD) and Corticosteroid-Resistant/Intolerant Autoimmune Inner Ear Disease Disease (CR-AIED)",
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"start_date": "2019-01-03",
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"days_late": null
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{
"registry_id": "NCT03786354",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03786354",
"title": "Prospective Evaluation of Shoulder Morbidity in Patients With Lymph-Node Positive Breast Cancer Receiving Regional Nodal Irradiation",
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"start_date": "2019-01-09",
"completion_date": "2025-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University Comprehensive Cancer Center",
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"days_late": null
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{
"registry_id": "NCT03593759",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03593759",
"title": "Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial",
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"start_date": "2019-01-15",
"completion_date": "2025-12-31",
"has_results": false,
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"sponsor_name": "Ottawa Heart Institute Research Corporation",
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"is_pact": false,
"days_late": null
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{
"registry_id": "NCT03347838",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03347838",
"title": "PD-1 Immune Checkpoint Inhibition for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers with or Without a History of Lung Cancer",
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"start_date": "2019-01-30",
"completion_date": "2025-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
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"days_late": null
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{
"registry_id": "NCT03822312",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03822312",
"title": "A Pilot Study of Digital Breast Tomosynthesis Guided Near-infrared Tomographic Optical Breast Imaging (DBT-TOBI) in Monitoring Response of Breast Cancer to Neoadjuvant Therapy",
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"start_date": "2019-02-01",
"completion_date": "2025-12-31",
"has_results": false,
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"sponsor_name": "Massachusetts General Hospital",
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{
"registry_id": "NCT03482479",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03482479",
"title": "Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis",
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"start_date": "2019-02-04",
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"title": "A Phase 3, Randomized, Double-Arm, Open-Label, Controlled Trial of ASP-1929 Photoimmunotherapy Versus Physician's Choice Standard of Care for the Treatment of Locoregional, Recurrent Head and Neck Squamous Cell Carcinoma in Patients Who Have Failed or Progressed On or After at Least Two Lines of Therapy, of Which at Least One Line Must Be Systemic Therapy",
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"title": "TENS (Transcutaneous Electrical Nerve Stimulation): Effect of Transcutaneous Spinal Direct Current Stimulation on Lower Limb Reflex, Volitional, and Functional Movement Post-stroke",
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"title": "Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus",
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"start_date": "2019-07-08",
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"title": "Strategies for Persistent Agitated Delirium in Palliative Care",
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"start_date": "2019-07-17",
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"title": "MATCH Treatment Subprotocol Z1L: BVD-523FB (Ulixertinib) in Patients With Tumors With BRAF Fusions, or With Non-V600E, Non-V600K BRAF Mutations",
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"start_date": "2019-07-24",
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"title": "Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis",
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"start_date": "2019-07-25",
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"title": "Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury",
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"start_date": "2019-07-26",
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"registry_id": "NCT04058652",
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"title": "Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site Pain",
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"start_date": "2019-08-07",
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"sponsor_name": "Wake Forest University Health Sciences",
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{
"registry_id": "NCT03873259",
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"title": "Burst Wave Lithotripsy (BWL) for the Comminution of Urinary Tract Stones: Intraoperative Evaluation of Safety and Effectiveness",
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"start_date": "2019-08-08",
"completion_date": "2025-12-31",
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"sponsor_name": "University of Washington",
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"registry_id": "NCT03929549",
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"title": "Preliminary Evaluation of a Remotely Controlled Mandibular Positioner to Predict Failure of Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea",
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"start_date": "2019-08-12",
"completion_date": "2025-12-31",
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"sponsor_name": "University of Michigan",
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"registry_id": "NCT04043195",
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"title": "Targeted Therapy With CDK4/6 Inhibitors in Chemo- Refractory/Relapsed, Rb Wild-type Extensive Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Lung Cancer, Extrapulmonary Small Cell Cancers and Other High Grade Neuroendocrine Cancers of the Lung, an Open Label Phase 2 Trial.",
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"title": "A Phase 2 Study of a Checkpoint Inhibitor in Men With Progressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation",
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"title": "Delayed Primary Closure Using Negative Pressure Wound Therapy",
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"title": "A Seamless Phase I/IIa Clinical Study to Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Severe and Critical COVID-19 Condition",
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}