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            "title": "The Use of Perfusion MRI Using Ferumoxytol and Small Molecular Weight Gadolinium (Gd) Agents to Assess Response to Pembrolizumab in Brain Metastases and Systemic Lesions in NSCLC: A Comparison of Imaging Modalities to Address Brain Metastases, Pseudoprogression, and Systemic Lesion Tumor Flare (Neuro-Check Pilot)",
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            "title": "Evaluation of the Safety, Tolerability, Efficacy, and Activity of AMX0035, a Fixed Combination of Phenylbutyrate (PB) and Tauroursodeoxycholic Acid (TUDCA), for Treatment of Amyotrophic Lateral Sclerosis: Open-Label Extension",
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            "title": "A Double-blind, Placebo- and Active-controlled Evaluation of the Safety and Efficacy of Levomilnacipran ER in Pediatric Patients 7-17 Years With Major Depressive Disorder",
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            "title": "Phase II Trial of Metronomic Capecitabine and Cyclophosphamide With Lapatinib and Trastuzumab in Patients With HER2 Positive Metastatic Breast Cancer Who Have Progressed on a Previous Trastuzumab-Based Regimen",
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            "title": "Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery",
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            "title": "A Randomized, Investigator Blinded, Single Site, Three Arm Clinical Study to Assess the Functional and Emotional Benefits of Replenix Power of Three Cream With Resveratrol , Replenix Power of Three Cream With Resveratrol With Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%, and Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%, Utilized to Treat Subjects With Facial Acne Vulgaris",
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            "title": "A Phase II Study of Nivolumab and Ipilimumab in Mucinous Colorectal and Appendiceal Tumors",
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            "title": "The Clinical Investigation of Stannous Fluoride Containing Toothpaste Compared to Colgate Cavity Protection Toothpaste in Reducing Plaque and Gingivitis - a Six-month Study in California",
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            "title": "Does the Use of a Nerve Stimulator Improve the Outcome of Ultrasound-Guided Supraclavicular Block (Anesthesia) for Upper Extremity Surgery?",
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            "title": "MATCH Treatment Subprotocol Z1B: Phase II Study of Palbociclib (PD-0332991) in Patients With Tumors With CCND1, 2, 3 Amplification",
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            "title": "An Open-Label Safety, Tolerability, and Pharmacokinetics Study of Eteplirsen in Young Patients With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping",
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            "title": "Phase II Trial of Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: \"The Minimalist Trial (MINT)\"",
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            "title": "Intracapsular and Intertrochanteric Fracture Fixation With the THP Hip Fracture Plating System",
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            "title": "A Phase 2a Open-label Study to Investigate Safety and Tolerability (Including the Maximum Tolerated Dose), Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of MT-3724 in Combination With Lenalidomide in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma",
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            "title": "A Phase 3 Study of Tirzepatide Monotherapy Compared to Dulaglutide 0.75 mg in Patients With Type 2 Diabetes Mellitus",
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            "title": "Randomized Double-Blind Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis B Virologically Suppressed for at Least Twelve Months on Tenofovir Disoproxil Fumarate, Tenofovir Alafenamide or Entecavir",
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            "title": "A Phase 3 Randomized Multicenter Study to Evaluate the Efficacy and Safety of Open-Label Dual Therapy With Oral Vonoprazan 20 mg or Double-Blind Triple Therapy With Oral Vonoprazan 20 mg Compared to Double-Blind Triple Therapy With Oral Lansoprazole 30 mg Daily in Patients With Helicobacter Pylori Infection",
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            "start_date": "2019-12-10",
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            "title": "A Clinical Investigation of the Safety and Efficacy of Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis",
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            "start_date": "2020-02-10",
            "completion_date": "2021-03-10",
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            "title": "Management of Diabetic Ketoacidosis in Children: Does Early Glargine Prevent Rebound Hyperglycemia?",
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            "title": "A Single-arm, Open-label, Multicenter Phase II Clinical Study of AK105 in Patients With Metastatic Nasopharyngeal Carcinoma After Failure of Second and Subsequent Lines of Chemotherapy",
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            "title": "Radiation Therapy Alone for Stage 1 and 2 MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma",
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            "title": "Phase 2 Trial of the Heat Shock Protein-90 (Hsp90) Inhibitor AT13387 (Onalespib) in Patients With Relapsed/Refractory ALK+ ALCL, Mantle Cell Lymphoma, and BCL6+ DLBCL",
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            "title": "Comparison of the Efficacy and Safety of Sirolimus, Everolimus or Mycophenolate in Renal Transplant Recipients Receiving Induction With Anti-thymocyte Globulin, Tacrolimus and Prednisone",
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            "start_date": "2017-06-18",
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            "title": "A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of AG-120 in Combination With Azacitidine in Subjects ≥ 18 Years of Age With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation",
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            "start_date": "2017-06-26",
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            "sponsor_name": "Institut de Recherches Internationales Servier",
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            "title": "Randomized Blinded Phase III Assessment of Second or Third-Line Chemotherapy With Docetaxel + Plinabulin Compared to Docetaxel + Placebo in Patients With Advanced Non-Small Cell Lung Cancer and With at Least One Measurable Lung Lesion",
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            "title": "Treatment of Depression With Connectivity Guided Robotically Delivered Repetitive Transcranial Magnetic Stimulation",
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            "start_date": "2017-08-17",
            "completion_date": "2021-03-23",
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            "sponsor_name": "The University of Texas Health Science Center at San Antonio",
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            "title": "A Proof of Concept Study to Determine the Efficacy of Entresto™ in HFpEF Based on Circulating Neprilysin Levels: The Circulating NEP and NEP Inhibition (CNEPi) Study",
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            "start_date": "2018-06-25",
            "completion_date": "2021-03-23",
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            "sponsor_name": "Mayo Clinic",
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            "days_late": null
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        {
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            "title": "A Randomized Pivotal Study of RenewTM NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Dementia of the Alzheimer's Type",
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            "start_date": "2018-11-12",
            "completion_date": "2021-03-23",
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            "sponsor_name": "Renew Research, LLC",
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            "status": "reported",
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            "title": "Evaluation of the Safety and Clinical Performance of the Gen 2 Connected Catheter - Wireless Urinary Prosthesis for Management of Chronic Urinary Retention",
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            "title": "The Impact of a Seated Compact Elliptical on Vital Signs and Range of Motion During Thirty Minutes of Activity",
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            "sponsor_name": "Indiana University",
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            "title": "A Phase 2 Study of Oral Selpercatinib (LOXO-292) in Patients With Advanced Solid Tumors, Including Rearranged in Transfection (RET) Fusion-Positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET Activation",
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            "start_date": "2020-03-16",
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            "title": "Use of an Occlusal Support Device During the Second Stage of Labor",
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            "sponsor_name": "University of Minnesota",
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        {
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            "title": "A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator-controlled Study to Evaluate the Safety and Tolerability of V114 in Healthy Infants (PNEU-LINK)",
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            "title": "The Role of Contrast Enhanced Ultrasound in The Diagnosis of Children With Appendicitis",
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            "start_date": "2019-01-04",
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            "start_date": "2019-03-18",
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            "sponsor_name": "University of Rochester",
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            "title": "A Pilot Study to Assess Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx",
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            "start_date": "2019-04-30",
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            "sponsor_name": "Powell Mansfield Inc.",
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        {
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            "title": "A Phase 2 Open Label Study Investigating the Efficacy and Safety of Roxadustat (FG-4592) for Treatment of Anemia in Patients Receiving Chemotherapy Treatment for Non-Myeloid Malignancies",
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            "start_date": "2019-08-20",
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            "title": "Clinical Safety and Effectiveness Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens",
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            "start_date": "2019-10-11",
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        {
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            "title": "A Phase 3 Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic HCV Infection and Compensated Cirrhosis",
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            "start_date": "2019-10-16",
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        {
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            "title": "A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Efficacy of SAGE-217 in the Treatment of Adult Subjects With Major Depressive Disorder",
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            "start_date": "2020-05-12",
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            "sponsor_name": "Biogen",
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            "title": "Clinical Study to Assess the Safety and Efficacy of the Tempsure® Firm for Non-invasive Lipolysis of the Flanks.",
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            "start_date": "2020-07-28",
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            "title": "A Phase 3 Study of the Safety and Efficacy of 1% and 2% Pilocarpine Ophthalmic Solutions Administered With the Optejet® Microdose Dispenser for Temporary Improvement of Near Vision in Adults With Presbyopia",
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            "start_date": "2020-12-15",
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            "sponsor_name": "Eyenovia Inc.",
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        {
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            "title": "Letrozole in Patients With Hepatopulmonary Syndrome: A Double-Blind Randomized Clinical Trial",
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            "start_date": "2021-02-18",
            "completion_date": "2021-03-26",
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            "sponsor_name": "Mayo Clinic",
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        {
            "registry_id": "NCT04774783",
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            "title": "Pilot Study on the Effects of Low-Level Laser Therapy Treatment for Acute and Persistent Discomfort",
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            "start_date": "2021-02-22",
            "completion_date": "2021-03-26",
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            "sponsor_name": "Arkansas Colleges of Health Education",
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            "sponsor_name": "Masonic Cancer Center, University of Minnesota",
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            "title": "A Phase II Protocol for Patients With Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent With Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging",
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            "sponsor_name": "Radiation Therapy Oncology Group",
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            "title": "2-Year Post-Approval Study to Investigate the STAR Ankle Under Actual Conditions of Use",
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            "sponsor_name": "Encore Medical, L.P.",
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            "title": "Effectiveness of Prolonged Use of IUD/Implant for Contraception",
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            "start_date": "2011-12-31",
            "completion_date": "2021-03-31",
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            "sponsor_name": "Indiana University",
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            "registry_id": "NCT01782443",
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            "title": "Phase II Study of Ziv-aflibercept in Patients With Advanced, Progressive Carcinoid Tumors",
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            "start_date": "2013-02-13",
            "completion_date": "2021-03-31",
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            "sponsor_name": "Dana-Farber Cancer Institute",
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            "title": "Randomized Noninferiority Study of an Antibacterial Envelope Alone Versus Envelope Plus Intraoperative Antibacterial Irrigant and Postoperative Antibiotics to Prevent Cardiac Implantable Electronic Device Infections in High-Risk Patients",
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            "title": "A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study of Atezolizumab With or Without Entinostat in Patients With Advanced Triple Negative Breast Cancer, With a Phase 1b Lead in Phase",
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            "title": "Phase I/II Study of Combination Immunotherapy for the Generation of HER-2/Neu (HER2) Specific Cytotoxic T Cells (CTL) in Vivo",
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            "title": "Cultural Acceptability and Feasibility of HPV Cervical Self Collection Aided by the Mobile",
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            "start_date": "2016-07-31",
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            "sponsor_name": "University of Virginia",
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            "days_late": 511
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}