HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 45658,
"recordsTotal": 45658,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=status&start=41700",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=status&start=41100",
"results": [
{
"registry_id": "NCT06865079",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06865079",
"title": "A Randomized, Double-blind, Placebo-controlled, 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Severe Tibio- Femoral Osteoarthritis of the Knee",
"has_exemption": false,
"start_date": "2025-05-09",
"completion_date": "2027-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "OrthoTrophix, Inc",
"sponsor_slug": "orthotrophix-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03887455",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03887455",
"title": "A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2019-03-27",
"completion_date": "2027-05-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Eisai Inc.",
"sponsor_slug": "eisai-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06453213",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06453213",
"title": "Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy",
"has_exemption": false,
"start_date": "2024-10-14",
"completion_date": "2027-05-26",
"has_results": false,
"results_due": false,
"sponsor_name": "SK Life Science, Inc.",
"sponsor_slug": "sk-life-science-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04785287",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04785287",
"title": "Phase I/II Trial of Anti-CTLA4-NF mAb (BMS-986218) in Combination With Nivolumab and Hypofractionated Stereotactic Radiation Therapy in Patients With Advanced Solid Malignancies",
"has_exemption": false,
"start_date": "2021-03-29",
"completion_date": "2027-05-27",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05173987",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05173987",
"title": "A Phase 3 Randomized, Open-label, Active-comparator Controlled Clinical Study of Pembrolizumab Versus Platinum Doublet Chemotherapy in Participants With Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma in the First-line Setting (KEYNOTE-C93/GOG-3064/ENGOT-en15)",
"has_exemption": false,
"start_date": "2022-02-03",
"completion_date": "2027-05-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06524414",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06524414",
"title": "A Phase 2, Randomized, Double-Blind Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Healthy Infants",
"has_exemption": false,
"start_date": "2024-07-25",
"completion_date": "2027-05-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06531941",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06531941",
"title": "An Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism Who Completed the 12-Week Treatment Period in the Phase 2 Study, MBX-2H1002 Study (Avail-Ext)",
"has_exemption": false,
"start_date": "2024-10-31",
"completion_date": "2027-05-27",
"has_results": false,
"results_due": false,
"sponsor_name": "MBX Biosciences",
"sponsor_slug": "mbx-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06016855",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06016855",
"title": "Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy (PRRT) in Patients With Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors",
"has_exemption": false,
"start_date": "2024-05-31",
"completion_date": "2027-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06968845",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06968845",
"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability and Efficacy of Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03) in Patients With Idiopathic Pulmonary Fibrosis",
"has_exemption": false,
"start_date": "2025-05-02",
"completion_date": "2027-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Rein Therapeutics",
"sponsor_slug": "rein-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05284747",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05284747",
"title": "EVOLVE-MI: A Pragmatic Randomized Multicenter Trial of EVOLocumab Administered Very Early to Reduce the Risk of Cardiovascular Events in Patients Hospitalized With Acute Myocardial Infarction",
"has_exemption": false,
"start_date": "2022-10-26",
"completion_date": "2027-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07026877",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07026877",
"title": "A Prospective, Multicenter, Non-Blinded, Non-Randomized Pivotal Study of the Fenestrated TREO Stent-Graft System in Subjects With Abdominal Aortic Aneurysms Requiring a Fenestrated Graft and Suitable for Endovascular Repair",
"has_exemption": false,
"start_date": "2025-09-29",
"completion_date": "2027-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Bolton Medical",
"sponsor_slug": "bolton-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03242642",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03242642",
"title": "Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO Trial",
"has_exemption": false,
"start_date": "2017-10-23",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiovascular",
"sponsor_slug": "medtronic-cardiovascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05786417",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05786417",
"title": "A Trial Comparing the Effectiveness and Tolerability of Medications in Older Adults With Stable Angina and Multiple Chronic Conditions: LIVEBETTER",
"has_exemption": false,
"start_date": "2023-05-10",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06436612",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06436612",
"title": "Phase II Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)",
"has_exemption": false,
"start_date": "2024-05-30",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06561087",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06561087",
"title": "Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions",
"has_exemption": false,
"start_date": "2025-02-27",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06476132",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06476132",
"title": "Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients: A Randomized, Multicenter, Double Blind, Placebo-Controlled Trial (CTOT-47)",
"has_exemption": false,
"start_date": "2025-03-12",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06916286",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06916286",
"title": "A Prospective, Randomized, Multi-center Trial Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06982820",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06982820",
"title": "A Prospective, Randomized, Double-blind, Controlled Study to Produce Guidelines for Integrating Prism for MDD Therapy (Reward System [RS] Upregulation) and to Demonstrate Its Superiority Over Sham Therapy",
"has_exemption": false,
"start_date": "2025-06-18",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GrayMatters Health Ltd.",
"sponsor_slug": "graymatters-health-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04480619",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04480619",
"title": "Safety and Efficacy of Ga-68-IAC Positron Emission Tomography (PET/CT) for Diagnosis and Clinical Management in Metastatic Breast Cancer Patients.",
"has_exemption": false,
"start_date": "2025-10-30",
"completion_date": "2027-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Advanced Imaging Projects, LLC",
"sponsor_slug": "advanced-imaging-projects-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01864109",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT01864109",
"title": "A Phase II Trial of Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma",
"has_exemption": false,
"start_date": "2013-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02656511",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02656511",
"title": "Immediate Initiation of Antiretroviral Therapy During Acute HIV Infection",
"has_exemption": false,
"start_date": "2015-12-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02727803",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02727803",
"title": "Personalized NK Cell Therapy in CBT",
"has_exemption": false,
"start_date": "2016-05-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03128879",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03128879",
"title": "A Phase II Study of Venetoclax (ABT-199) Consolidation for Patients Currently Receiving Ibrutinib or Acalabrutinib for High-risk CLL",
"has_exemption": false,
"start_date": "2017-06-16",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03233399",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03233399",
"title": "Modulating Movement Intention Via Cortical Stimulation in Healthy Subjects and Patients With Psychogenic Movement Disorders and Non-epileptic Seizures",
"has_exemption": false,
"start_date": "2017-07-20",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03384836",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03384836",
"title": "A Phase Ib/II Study of Propranolol With Fixed-Dose Pembrolizumab in Patients With Unresectable Stage III and Stage IV Melanoma",
"has_exemption": false,
"start_date": "2018-01-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03667651",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03667651",
"title": "THE PEBBLES STUDY: A Randomised Controlled Trial to Prevent Eczema, Food Allergy and Sensitisation Using a Skin Barrier Improvement Strategy",
"has_exemption": false,
"start_date": "2018-03-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Melbourne",
"sponsor_slug": "university-of-melbourne",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03924895",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03924895",
"title": "A Randomized Phase 3 Study Evaluating Cystectomy With Perioperative Pembrolizumab and Cystectomy With Perioperative Enfortumab Vedotin and Pembrolizumab Versus Cystectomy Alone in Participants Who Are Cisplatin-Ineligible or Decline Cisplatin With Muscle-Invasive Bladder Cancer (KEYNOTE-905/EV-303)",
"has_exemption": false,
"start_date": "2019-07-24",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05999994",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05999994",
"title": "CAMPFIRE: Children's and Young Adult Master Protocol for Innovative Pediatric Research",
"has_exemption": false,
"start_date": "2020-01-22",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04293185",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04293185",
"title": "A Phase 3 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo With the BB305 Lentiviral Vector in Subjects With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2020-02-14",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "bluebird bio",
"sponsor_slug": "bluebird-bio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04420702",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04420702",
"title": "Diffusion Basis Spectrum Imaging of the Prostate: A Virtual Biopsy to Accurately Diagnose Prostate Cancer",
"has_exemption": false,
"start_date": "2020-02-27",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04322955",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04322955",
"title": "Cyto-KIK; TRIAL (CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy (Nivolumab) and Targeted Kinase Inhibition (Cabozantinib)",
"has_exemption": false,
"start_date": "2020-06-22",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mark Stein",
"sponsor_slug": "mark-stein",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04485286",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04485286",
"title": "Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury",
"has_exemption": false,
"start_date": "2020-07-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04736173",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04736173",
"title": "Official Title: A Phase 2 Study to Evaluate Zimberelimab (AB122) Combined With AB154 in Front-Line, PD-L1-High, Locally Advanced or Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2021-02-08",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arcus Biosciences, Inc.",
"sponsor_slug": "arcus-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04721132",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04721132",
"title": "An Open-Label, Phase II, Pre-Operative Study of Atezolizumab Plus Bevacizumab for Resectable Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2021-02-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04775485",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04775485",
"title": "FIREFLY-1: A Phase 2, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of the Oral Pan-RAF Inhibitor DAY101 in Pediatric Patients With RAF-Altered, Recurrent or Progressive Low-Grade Glioma and Advanced Solid Tumors",
"has_exemption": true,
"start_date": "2021-04-22",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Day One Biopharmaceuticals, Inc.",
"sponsor_slug": "day-one-biopharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04957615",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04957615",
"title": "A Phase II Clinical Trial to Investigate ARID1A Mutation and CXCL13 Expression in the Pre-Treatment Tumor Samples as a Combinatorial Predictive Biomarker for Immune Checkpoint Therapy in Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2021-09-21",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04833140",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04833140",
"title": "Estrogen Administration for the Treatment of NASH in Postmenopausal Women",
"has_exemption": false,
"start_date": "2021-12-02",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04599504",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04599504",
"title": "Pharmacological and Behavioral Treatments to Treat Loss-of-Control Eating and Improve Weight Outcomes After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)",
"has_exemption": false,
"start_date": "2022-01-02",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04605081",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04605081",
"title": "Pharmacological and Behavioral Treatments to Treat Loss-of-Control Eating and Improve Weight Outcomes After Bariatric Surgery: Maintenance Treatment (Stage 2a)",
"has_exemption": false,
"start_date": "2022-01-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04380740",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04380740",
"title": "A Randomized Double-Blind Trial of Abatacept Extended Dosing Versus Abatacept Short-term Dosing for Graft Versus Host Disease Prophylaxis: \"ABA3\"",
"has_exemption": false,
"start_date": "2022-03-30",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05081128",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05081128",
"title": "A Placebo-Controlled Efficacy in iNPH Shunting (PENS) Trial",
"has_exemption": false,
"start_date": "2022-05-18",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03828201",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03828201",
"title": "Prospective, Randomized, Partially Blinded, Phase 2 Study of the Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine for Treatment of Patients With MDR-TB",
"has_exemption": false,
"start_date": "2022-06-07",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston University",
"sponsor_slug": "boston-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05392946",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05392946",
"title": "Phase 1/2 Trial of Iberdomide in Combination With Daratumumab, BortEzomib and DexamethAsone in Patients With Newly Diagnosed Multiple MyeLoma (IDEAL)",
"has_exemption": false,
"start_date": "2022-08-11",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05254327",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05254327",
"title": "A Randomized Phase 2 Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With and Without BMX-001 as Part of Total Neoadjuvant Therapy in Patients With Newly Diagnosed Locally Advanced Rectal Adenocarcinoma",
"has_exemption": false,
"start_date": "2022-08-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05318417",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05318417",
"title": "A Post-approval, Prospective, Nonrandomized, Single-arm Multicenter Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness",
"has_exemption": false,
"start_date": "2022-08-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cochlear",
"sponsor_slug": "cochlear",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05272254",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05272254",
"title": "Povidone Iodine Efficacy Study",
"has_exemption": false,
"start_date": "2022-09-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05456321",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05456321",
"title": "tDCS and Cognitive Training as a Neurodevelopmental Intervention in FASD",
"has_exemption": false,
"start_date": "2022-11-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05378347",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05378347",
"title": "Endurant Stent Graft System vs Excluder Endoprothesis: A Global, Prospective, Randomized Clinical Trial in Sac Regression",
"has_exemption": false,
"start_date": "2023-01-05",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiovascular",
"sponsor_slug": "medtronic-cardiovascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06874855",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06874855",
"title": "Lemborexant in Delayed Sleep Phase Syndrome",
"has_exemption": false,
"start_date": "2023-03-13",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05562167",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05562167",
"title": "The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF) -a Phase II Clinical Trial",
"has_exemption": false,
"start_date": "2023-03-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05500963",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05500963",
"title": "Reducing Fatigue in People With Multiple Sclerosis by Treatment With Transcutaneous Electrical Nerve Stimulation",
"has_exemption": false,
"start_date": "2023-04-25",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Boulder",
"sponsor_slug": "university-of-colorado-boulder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05671861",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05671861",
"title": "Design of a Low-Cost Therapeutic Device for Patients With Radiation-Related Trismus",
"has_exemption": false,
"start_date": "2023-04-27",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05794880",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05794880",
"title": "Matched Unrelated Donor and Partially Matched Related Donor Peripheral Stem Cell Transplantation With Alpha/Beta T-Cell and B-Cell Depletion for Patients With Hematologic Malignancies With Targeted ATG Dosing Pilot Study, IDE 13641",
"has_exemption": false,
"start_date": "2023-05-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05295680",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05295680",
"title": "A Study of Oral Hymecromone to Treat Adolescents and Adults With Primary Sclerosing Cholangitis(HAAPS Study).",
"has_exemption": false,
"start_date": "2023-05-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aparna Goel",
"sponsor_slug": "aparna-goel",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05712057",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05712057",
"title": "Neurostimulation Enhanced Cognitive Restructuring for Transdiagnostic Emotional Dysregulation: A Component Analysis",
"has_exemption": false,
"start_date": "2023-05-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05589818",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05589818",
"title": "A Phase II Study of the Effects of Pembrolizumab on Quality of Life for Patients With Treatment-Naïve, Advanced or Metastatic NSCLC and Poor Performance Status",
"has_exemption": false,
"start_date": "2023-05-26",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05209165",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05209165",
"title": "Semaglutide as Treatment of Overweight and Obese Individuals to Reduce Atrial Fibrillation Burden",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "San Francisco Veterans Affairs Medical Center",
"sponsor_slug": "san-francisco-veterans-affairs-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05881408",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05881408",
"title": "A Phase 3, Multinational, Randomized, Double-Blind, Placebo-Controlled Systemic Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of SRP- 9001 in Non-Ambulatory and Ambulatory Subjects With Duchenne Muscular Dystrophy (ENVISION)",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarepta Therapeutics, Inc.",
"sponsor_slug": "sarepta-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06231342",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06231342",
"title": "Endotracheal Tube (ETT) 180: Stylet-loaded Endotracheal Tube Rotation Before Insertion to Decrease the Risk of Postoperative Sore Throat: a Randomized Double-Blind Prospective Trial.",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University",
"sponsor_slug": "ohio-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05694871",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05694871",
"title": "Official Title a Randomized Phase 2 Trial with a Safety Lead-In to Evaluate Palbociclib Versus Palbociclib and Cemiplimab for the Treatment of Advanced Dedifferentiated Liposarcoma",
"has_exemption": false,
"start_date": "2023-06-07",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance for Clinical Trials in Oncology",
"sponsor_slug": "alliance-for-clinical-trials-in-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05845814",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05845814",
"title": "A Phase 1/2 Randomized, Umbrella Study to Evaluate the Safety and Efficacy of Pembrolizumab Plus Enfortumab Vedotin (EV) in Combination With Investigational Agents Versus Pembrolizumab Plus EV, as First-Line Treatment for Participants With Advanced Urothelial Carcinoma (KEYMAKER-U04): Substudy 04B",
"has_exemption": false,
"start_date": "2023-06-23",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05853939",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05853939",
"title": "Inducing and Measuring Visual-evoked Potential Plasticity in Humans With Repetitive Transcranial Magnetic Stimulation",
"has_exemption": false,
"start_date": "2023-07-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05801939",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05801939",
"title": "Phase 2 Study of Cevostamab Consolidation Following BCMA CAR T Cell Therapy for Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2023-07-11",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05819866",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05819866",
"title": "A Clinical Study to Assess the Efficacy and Safety of Leriglitazone in Adult Male Subjects With Cerebral Adrenoleukodystrophy",
"has_exemption": false,
"start_date": "2023-07-12",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Minoryx Therapeutics, S.L.",
"sponsor_slug": "minoryx-therapeutics-sl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05816122",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05816122",
"title": "MS-DETECT: Early Detection of Multiple Sclerosis Progression With MSCopilot® Detect",
"has_exemption": false,
"start_date": "2023-09-22",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ad scientiam",
"sponsor_slug": "ad-scientiam",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05583617",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05583617",
"title": "A Platform Study Evaluating the Safety and Efficacy of Multiple Treatments in Patients With Multiple Myeloma",
"has_exemption": false,
"start_date": "2023-11-14",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05996627",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05996627",
"title": "Randomized Phase II Study of Belumosudil vs. Placebo for Preemptive Treatment of Chronic Graft Versus Host Disease",
"has_exemption": false,
"start_date": "2023-12-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05766371",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05766371",
"title": "A Phase 2 Study of Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Metastatic Castration Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2023-12-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05903859",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05903859",
"title": "Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)",
"has_exemption": false,
"start_date": "2024-01-18",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06169124",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06169124",
"title": "A Phase II Study of Androgen Receptor (AR) Inhibition by Darolutamide in Combination With Leuprolide Acetate and Exemestane in Recurrent Adult-Type Ovarian Granulosa Cell Tumor",
"has_exemption": false,
"start_date": "2024-02-08",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05483010",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05483010",
"title": "Pilot Study of Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)",
"has_exemption": false,
"start_date": "2024-02-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05701111",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05701111",
"title": "Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress",
"has_exemption": false,
"start_date": "2024-02-23",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05513027",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05513027",
"title": "A Prospective Study of the Augmented Whole-body Scanning Via Magnifying PET/CT (AWSM-PET/CT) Techniques Abilities to Improve Upon the Diagnostic Accuracy of the Standard-of-care (SOC) PET/CT for Malignant Lesion Detection",
"has_exemption": false,
"start_date": "2024-03-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06237426",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06237426",
"title": "A 52-Week, Open-Label Evaluation of the Long-term Efficacy and Safety of Single and Repeated Treatments with Methylone for the Treatment of PTSD IMPACT-EXT (Investigation of Methylone for Post-Traumatic Stress Disorder [PTSD])",
"has_exemption": false,
"start_date": "2024-03-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Transcend Therapeutics",
"sponsor_slug": "transcend-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06003153",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06003153",
"title": "GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH",
"has_exemption": false,
"start_date": "2024-03-12",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06253663",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06253663",
"title": "A Phase 2 Multicenter Study Evaluating the Safety and the Efficacy of KTE-X19 in Adult Japanese Subjects With Relapsed/Refractory Mantle Cell Lymphoma or Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2024-03-18",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06319027",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06319027",
"title": "Phase II Glioblastoma Accelerated Biomarkers Learning Environment Trial (GABLE)",
"has_exemption": false,
"start_date": "2024-04-11",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05880810",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05880810",
"title": "Continuous Glucose Monitor Use for Mayo Clinic Advanced Care at Home Patients With Diabetes Mellitus",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06214949",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06214949",
"title": "Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) as a Treatment for Chronic Neck Pain",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
"sponsor_slug": "henry-m-jackson-foundation-for-the-advancement-of-military-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06249048",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06249048",
"title": "A Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of STX-001 Delivered by Intratumoral Injection in Patients With Advanced Solid Tumors as a Monotherapy or in Combination With Pembrolizumab",
"has_exemption": false,
"start_date": "2024-05-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Strand Therapeutics Inc.",
"sponsor_slug": "strand-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06411821",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06411821",
"title": "Phase 2 Trial of Ulixertinib for Patients With Histiocytic Neoplasms",
"has_exemption": false,
"start_date": "2024-05-07",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06364176",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06364176",
"title": "Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Kansas Medical Center",
"sponsor_slug": "university-of-kansas-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439277",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06439277",
"title": "Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for the Treatment of Obesity and Weight-Related Comorbidities in Adolescents: A Randomized, Double-Blind, Placebo- Controlled Trial (SURMOUNT-ADOLESCENTS-2)",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06411249",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06411249",
"title": "A Phase 4, Multicenter, Prospective, Open-Label Study Describing the Efficacy and Safety of Belimumab Administered Subcutaneously in Adult Participants With Early Systemic Lupus Erythematosus",
"has_exemption": false,
"start_date": "2024-06-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06259006",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06259006",
"title": "TREAT-SC: A Randomised, Double-Blinded, Placebo-Controlled Trial of Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children",
"has_exemption": false,
"start_date": "2024-06-17",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Starship Child Health, Te Toka Tumai Auckland",
"sponsor_slug": "starship-child-health-te-toka-tumai-auckland",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06494072",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06494072",
"title": "Short Versus Standard of Care Antibiotic Duration for Hospitalized Children With Uncomplicated Community-acquired Pneumonia: a Non-inferiority, Randomized Controlled Trial.",
"has_exemption": false,
"start_date": "2024-08-22",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06351111",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06351111",
"title": "Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study",
"has_exemption": false,
"start_date": "2024-08-29",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas at Dallas",
"sponsor_slug": "the-university-of-texas-at-dallas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06247098",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06247098",
"title": "Sinus Augmentation Healing With Autogenous and Xenograft Mix Compared to Xenograft Alone",
"has_exemption": false,
"start_date": "2024-09-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tufts University",
"sponsor_slug": "tufts-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06053814",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06053814",
"title": "A Phase 1/2, First in Human, Multiple-dose, 2-part Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NS-050/NCNP-03 in Boys With Duchenne Muscular Dystrophy (DMD)",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NS Pharma, Inc.",
"sponsor_slug": "ns-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06592794",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06592794",
"title": "A Phase 3, Randomized, Observer-blinded, Placebo-controlled Study to Evaluate the Safety and Efficacy of mRNA-1403, a Multivalent Candidate Vaccine to Prevent Norovirus Acute Gastroenteritis in Adults ≥18 Years of Age",
"has_exemption": false,
"start_date": "2024-09-24",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ModernaTX, Inc.",
"sponsor_slug": "modernatx-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06628908",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06628908",
"title": "A Phase 3, Randomized, Double-blind, Placebo- and Active-Controlled Study of the Efficacy and Safety of Suzetrigine in Subjects With Pain Associated With Diabetic Peripheral Neuropathy",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06240754",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06240754",
"title": "A Pilot Study of Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2: A Decentralized Trial",
"has_exemption": false,
"start_date": "2024-10-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06625060",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06625060",
"title": "A Multicentre, Randomised, Double-blind, Placebo-controlled, Dose Escalation and Dose Finding Phase II Study to Evaluate the Safety and Efficacy of IPN10200 in the Prevention of Episodic or Chronic Migraine in Adults",
"has_exemption": false,
"start_date": "2024-10-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609577",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06609577",
"title": "Personalized Ultrasound Guided Pacing of the External Diaphragm to Improve Outcomes in Patients Undergoing Invasive Mechanical Ventilation: a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daishan Jiang",
"sponsor_slug": "daishan-jiang",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06710288",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06710288",
"title": "A Phase 2, Open-label, Single-arm Study Of Autologous Memory Cytokine Enriched Natural Killer (M-CENK) Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian Cancer",
"has_exemption": false,
"start_date": "2024-11-06",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ImmunityBio, Inc.",
"sponsor_slug": "immunitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06537414",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06537414",
"title": "A Phase 2b, Multi-centre, Randomized, Partially Placebo-controlled, Double-blind Study to Investigate the Safety and Efficacy of Sequential Therapy With Daplusiran/Tomligisiran Followed by Bepirovirsen in Participants With Chronic Hepatitis B Virus on Background Nucleos(t)Ide Analogue Therapy (B-United)",
"has_exemption": false,
"start_date": "2024-11-11",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06191848",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06191848",
"title": "Effect of Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA): A Randomized, Double-Blind, Placebo-Controlled Trial",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Melbourne",
"sponsor_slug": "university-of-melbourne",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06435845",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06435845",
"title": "A Phase 2, Multicenter, Open-label Study to Evaluate the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization",
"has_exemption": false,
"start_date": "2024-11-21",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rallybio",
"sponsor_slug": "rallybio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06718101",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06718101",
"title": "A Phase 2 Multicenter Platform Trial of Targeted Immunomodulator Therapies for Moderate to Severe Atopic Dermatitis",
"has_exemption": false,
"start_date": "2024-12-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06648642",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06648642",
"title": "An Open-label Clinical Trial of IR-TMS for AUD and Development of a Neurobiological Biomarker for Craving and Relapse Validated Using a Direct Biochemical Biomarker (phosphatidylethanol) of Alcohol Use",
"has_exemption": false,
"start_date": "2025-02-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05837845",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05837845",
"title": "A Randomized Trial to Compare MDMA-assisted Cognitive Processing Therapy (aCPT) Versus a VA Standard-of-care CPT for the Treatment of Severe Posttraumatic Stress Disorder Among Veterans",
"has_exemption": false,
"start_date": "2025-02-10",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Patricia Suppes",
"sponsor_slug": "patricia-suppes",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06798844",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06798844",
"title": "Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-02-28",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Universitaire Ziekenhuizen KU Leuven",
"sponsor_slug": "universitaire-ziekenhuizen-ku-leuven",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05492266",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05492266",
"title": "Expiratory Muscle Strength Training as a Non-surgical Option for Velopharyngeal Dysfunction: A Randomized-controlled Trial",
"has_exemption": false,
"start_date": "2025-03-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Noel Jabbour",
"sponsor_slug": "noel-jabbour",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06874621",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06874621",
"title": "VY7523-102: A Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Ascending Intravenous Doses of VY7523 in Participants With Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2025-03-03",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Voyager Therapeutics",
"sponsor_slug": "voyager-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06784947",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06784947",
"title": "A Phase II Trial of Tiragolumab in Combination With Atezolizumab and Bevacizumab in Patients With Previously Treated, Microsatellite Stable, Metastatic Colorectal Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-03-25",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843577",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06843577",
"title": "A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects",
"has_exemption": false,
"start_date": "2025-03-27",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zona Health, Inc",
"sponsor_slug": "zona-health-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06568601",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06568601",
"title": "Reducing Veterans' Risk of Atherosclerotic Cardiovascular Disease Through Pharmacogenomics Informed Statin Prescribing",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06858111",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06858111",
"title": "Phase III Randomized Control Trial to Investigate the Safety and Efficacy of Fertilo Versus Medicult In Vitro Maturation (IVM)",
"has_exemption": false,
"start_date": "2025-04-17",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gameto, Inc.",
"sponsor_slug": "gameto-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06919926",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06919926",
"title": "A Randomized, Within-subject, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of AGB101 (Low-dose Levetiracetam, 220 mg, Extended Release Tablet) for the Treatment of Hippocampal Overactivity in the Elderly",
"has_exemption": false,
"start_date": "2025-04-17",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06914895",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06914895",
"title": "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Evaluating the Efficacy and Safety of Tirzepatide Once Weekly Compared to Placebo in Adult Participants With Type 1 Diabetes and Obesity or Overweight",
"has_exemption": false,
"start_date": "2025-04-25",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06988670",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06988670",
"title": "A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Trial Investigating the Safety, Tolerability and Efficacy of EXT608 in Adults With Hypoparathyroidism",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Extend Biosciences Inc.",
"sponsor_slug": "extend-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06935357",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06935357",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Felzartamab in Adults With IgA Nephropathy (PREVAIL)",
"has_exemption": false,
"start_date": "2025-05-08",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07010029",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07010029",
"title": "Coronary Sinus Reducer in Patients With Angina With no Obstructive Coronary Disease: a Prospective Single-arm Study",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of Warsaw",
"sponsor_slug": "medical-university-of-warsaw",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06996379",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06996379",
"title": "Use of the J-Tip Needle-Free Injection System With 1% Lidocaine to Reduce Paracentesis-Related Discomfort",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06729996",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06729996",
"title": "Randomized, Parallel Group, Dose Escalation Trial of Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus: The PEP-DM Trial",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06912646",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06912646",
"title": "An Evaluation of the Effect of the Erchonia® EVRL™ for Prescription Home Use Application in Providing Temporary Relief From Idiopathic Peripheral Neuropathy Foot Pain",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Erchonia Corporation",
"sponsor_slug": "erchonia-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06915454",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06915454",
"title": "High-resolution Specimen PET-CT Imaging for the Intraoperative Visualization of Resection Margins: an Exploratory Study",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06920004",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06920004",
"title": "A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Intravenous Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelinating Polyneuropathy",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "argenx",
"sponsor_slug": "argenx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06921837",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06921837",
"title": "A Phase 1/2, First-in-Human, Dose Escalation and Expansion Study of BDC-4182 as a Single Agent in Patients With Advanced Gastric and Gastroesophageal Cancer",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bolt Biotherapeutics, Inc.",
"sponsor_slug": "bolt-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07018323",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07018323",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease",
"has_exemption": false,
"start_date": "2025-06-19",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunovant Sciences GmbH",
"sponsor_slug": "immunovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07092059",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07092059",
"title": "Decentralized Clinical Trial of Contingency Management Digital Therapeutic to Treat Stimulant Use Disorder",
"has_exemption": false,
"start_date": "2025-06-24",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DynamiCare Health",
"sponsor_slug": "dynamicare-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06907979",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06907979",
"title": "Experimental Manipulation of the Emotional Salience of Cannabis Use-Related Information in Regular Cannabis Users",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Auburn University",
"sponsor_slug": "auburn-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076407",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07076407",
"title": "A Phase 3, Randomized, Double-blind, Placebo-Controlled, Multicenter Study to Evaluate Azetukalner in Moderate-to-Severe Major Depressive Disorder",
"has_exemption": false,
"start_date": "2025-07-08",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Xenon Pharmaceuticals Inc.",
"sponsor_slug": "xenon-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06903819",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06903819",
"title": "Ketamine's Impact on Opioid Use, Pain, and Mental Health in Polytraumatized Orthopedic Patients: A Randomized Controlled Trial (KOPM)",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Texas Tech University Health Sciences Center",
"sponsor_slug": "texas-tech-university-health-sciences-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06988488",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06988488",
"title": "A Phase 1b/2a, Multicenter, Open-label Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Celgene",
"sponsor_slug": "celgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06974604",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06974604",
"title": "Prevention of Datopotamab Deruxtecan (TROP-2 Directed ADC) Associated Stomatitis in Patients With HER2-negative Metastatic Breast Cancer or Non-small Cell Lung Cancer Using Dexamethasone Mouthwash: a Single-arm, Phase 2 Trial (TROPION- DM, 2023-ESR-000087)",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brown University",
"sponsor_slug": "brown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07094087",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07094087",
"title": "A Phase 3, Multicenter, Randomized, Open-label, Controlled Study to Investigate the Efficacy and Safety of 4-Factor Prothrombin Complex Concentrate in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CSL Behring",
"sponsor_slug": "csl-behring",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06776783",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06776783",
"title": "A Randomized, Controlled, Blinded, Parallel Group Study of the Safety and Efficacy of APC-0101 (SF-RI 1 Surfactant for Inhalation Combined With a Dedicated Delivery System) in Preterm Infants With Respiratory Distress Syndrome",
"has_exemption": false,
"start_date": "2025-08-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aerogen Pharma Limited",
"sponsor_slug": "aerogen-pharma-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05107934",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05107934",
"title": "International, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "R-Pharm Overseas, Inc.",
"sponsor_slug": "r-pharm-overseas-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05646563",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05646563",
"title": "A Phase II, Open-Label Study of NM8074 in Soliris®-Treated Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07062471",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07062471",
"title": "Prospective, Multi-center, Single-arm Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE Study)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shockwave Medical, Inc.",
"sponsor_slug": "shockwave-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06286046",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06286046",
"title": "A Phase 2, Open-label, Multicenter Study of Mitapivat in Subjects With Sickle Cell Disease and Nephropathy (RESIST)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Agios Pharmaceuticals, Inc.",
"sponsor_slug": "agios-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06691919",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06691919",
"title": "Surgical vs Endoscopic Resection Of Walled Off Pancreatic Necrosis Using The Powered Endoscopic Debridement (PED) System - The SERPENT Trial",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2027-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02997228",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02997228",
"title": "Colorectal Cancer Metastatic dMMR/MSI-H Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab/Atezolizumab Combination Versus Single Agent Atezolizumab in the First-Line Treatment of Patients With Deficient DNA Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2018-01-19",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03598257",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03598257",
"title": "A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently With Radiotherapy Versus Radiotherapy Alone for Inflammatory Breast Cancer",
"has_exemption": false,
"start_date": "2019-01-18",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03906422",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03906422",
"title": "Comparison of Patient-reported Pain After Initial Archwire Placement With Three Types of Nickel-titanium Archwires: a Prospective Triple-blind, Randomized Controlled Clinical Trial",
"has_exemption": false,
"start_date": "2019-05-10",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03775265",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03775265",
"title": "Phase III Randomized Trial of Concurrent Chemoradiotherapy With or Without Atezolizumab in Localized Muscle Invasive Bladder Cancer",
"has_exemption": false,
"start_date": "2019-06-03",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04040205",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04040205",
"title": "Abemaciclib for Treatment of Advanced Bone and Soft Tissue Sarcoma Identified as Having CDK Pathway Alteration",
"has_exemption": false,
"start_date": "2019-10-07",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04291378",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04291378",
"title": "The DBCG Proton Trial. Adjuvant Breast Proton Radiation Therapy for Early Breast Cancer Patients: The Skagen Trial 2, a Clinically Controlled Randomised Phase III Trial",
"has_exemption": false,
"start_date": "2020-06-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Danish Breast Cancer Cooperative Group",
"sponsor_slug": "danish-breast-cancer-cooperative-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04644068",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04644068",
"title": "A Modular Phase I/IIa, Open-label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Ascending Doses of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies",
"has_exemption": false,
"start_date": "2020-11-12",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05055297",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05055297",
"title": "SELUTION SLR™ 014 BTK: A Prospective Randomized Multicenter Single Blinded Study to Assess the Safety and Effectiveness of the SELUTION SLR™ 014 Drug Eluting Balloon in the Treatment of Below-the-Knee (BTK) Atherosclerotic Disease in Patients With Chronic Limb Threatening Ischemia (CLTI)",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.A. Med Alliance S.A.",
"sponsor_slug": "ma-med-alliance-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05379868",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05379868",
"title": "Posterior Column Spinal Osteotomies in the Treatment of Adolescent Idiopathic Scoliosis. A Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2022-06-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Turku University Hospital",
"sponsor_slug": "turku-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05366829",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05366829",
"title": "Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2022-07-25",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rutgers, The State University of New Jersey",
"sponsor_slug": "rutgers-the-state-university-of-new-jersey",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05317858",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05317858",
"title": "A Randomized Pivotal Study Assessing the Safety and Efficacy of Targeted Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound During the Standard of Care Treatment of Brain Metastases of Non-small Cell Lung Cancer (NSCLC) Origin",
"has_exemption": false,
"start_date": "2022-08-12",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "InSightec",
"sponsor_slug": "insightec",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05331144",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05331144",
"title": "Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid, and Tau in Older Adults (IPAT Study)",
"has_exemption": false,
"start_date": "2022-10-25",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rong Zhang",
"sponsor_slug": "rong-zhang",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06043817",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06043817",
"title": "First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations",
"has_exemption": false,
"start_date": "2023-09-26",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Antares Therapeutics, Inc",
"sponsor_slug": "antares-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05763953",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05763953",
"title": "The NODE-202 Study Multi-Center, Multi-National, Open-Label, Efficacy and Safety Study of Etripamil Nasal Spray in Pediatric Patients With Paroxysmal Supraventricular Tachycardia",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Milestone Pharmaceuticals Inc.",
"sponsor_slug": "milestone-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05458674",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05458674",
"title": "A Phase II Study of the Safety, Tolerability and Antitumor Activity of Tucatinib in Combination with Eribulin and Trastuzumab in Patients with Pretreated Unresectable Locally Advanced or Metastatic HER2+ Breast Cancer",
"has_exemption": false,
"start_date": "2024-01-30",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Criterium, Inc.",
"sponsor_slug": "criterium-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06266793",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06266793",
"title": "Comparison of Lumenis Pulse 120H Moses 2.0 Holmium Laser vs. Olympus Soltive Thulium Fiber Laser for Mini-percutaneous Nephrolithotomy",
"has_exemption": false,
"start_date": "2024-03-07",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "MaineHealth",
"sponsor_slug": "mainehealth",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05937854",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05937854",
"title": "Effect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary Hypertension",
"has_exemption": false,
"start_date": "2024-04-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05972551",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05972551",
"title": "A Phase 3, Open-Label, Multicenter, Randomized Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta",
"has_exemption": false,
"start_date": "2024-04-22",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05665361",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05665361",
"title": "A Phase I/II Study of Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)",
"has_exemption": false,
"start_date": "2024-04-24",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06307548",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06307548",
"title": "Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Loco-Regionally Advanced or Recurrent Colorectal Cancer Undergoing Surgery - Phase I/II",
"has_exemption": false,
"start_date": "2024-07-30",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06280950",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06280950",
"title": "Expanding Liver Transplant Immunosuppression Minimization Via Everolimus (CTOT-43)",
"has_exemption": false,
"start_date": "2024-09-12",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06388564",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06388564",
"title": "A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease",
"has_exemption": false,
"start_date": "2024-10-11",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Incyte Corporation",
"sponsor_slug": "incyte-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06311591",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06311591",
"title": "Evaluation of Efficacy, Effectiveness, and Implementation of Jaspr Health's Digital Platform in Emergency Department for Patients With Suicidal Risk - Part B: Real-World Study (RWS)",
"has_exemption": false,
"start_date": "2024-11-07",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Massachusetts, Worcester",
"sponsor_slug": "university-of-massachusetts-worcester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06532006",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06532006",
"title": "A Randomized, Double-blinded, Multicenter, Phase Ⅲ Clinical Study of HLX22 (Recombinant Humanized Anti-HER2 Monoclonal Antibody Injection) in Combination With Trastuzumab and Chemotherapy (XELOX) Versus Trastuzumab and Chemotherapy (XELOX) With or Without Pembrolizumab for the First Line Treatment of Locally Advanced or Metastatic Gastroesophageal Junction and Gastric Cancer",
"has_exemption": false,
"start_date": "2024-11-22",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Henlius Biotech",
"sponsor_slug": "shanghai-henlius-biotech",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06841614",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06841614",
"title": "Evaluation of the Efficacy of a Post-exposure Prophylaxis (PEP) Strategy in Contacts At High Risk of Developing Ebola Virus Disease (EVD)",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "ANRS, Emerging Infectious Diseases",
"sponsor_slug": "anrs-emerging-infectious-diseases",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06936566",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06936566",
"title": "Phase 2 Study of Ruxolitinib-Based Primary Treatment for Acute GVHD",
"has_exemption": false,
"start_date": "2025-05-14",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "John Levine",
"sponsor_slug": "john-levine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06658002",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06658002",
"title": "Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06852963",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06852963",
"title": "A Repeat-Dose, Open-Label, Four Arm Safety and Efficacy Study of Two Doses of VP-001 (75ug and 120ug) Administered Intravitreally in Participants with Confirmed PRPF31 Mutation-Associated Retinal Dystrophy and Previously Treated with VP001 in the PLATYPUS Study (Protocol# VP001-101) or WALLABY Study (Protocol #VP001-102) for a Minimum of 8 Weeks",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "PYC Therapeutics",
"sponsor_slug": "pyc-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06752694",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06752694",
"title": "Ruxolitinib Based GVHD Prophylaxis Regimen for Older Adults Receiving Non-ATG Containing Non-Myeloablative Hematopoietic Cell Transplantation for Acquired Aplastic Anemia",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06989762",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06989762",
"title": "Use of an Intraabdominal Pressure Monitoring Urinary Catheter After Cardiac Surgery to Improve Kidney Perfusion Pressure: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dang Tan Phat",
"sponsor_slug": "dang-tan-phat",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07032675",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07032675",
"title": "Cartilage Remodeling Using Low-Temperature Radiofrequency for Facial Reconstruction",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04383262",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04383262",
"title": "A 12-Week Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Assess the Efficacy of Oral Fosamprenavir for Laryngopharyngeal Reflux",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07087678",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07087678",
"title": "A Prospective, Randomised, Open Label Feasibility Trial Comparing BurstDR Microdosing Versus Tonic Occipital Nerve Stimulation for Patients With Refractory Chronic Migraine",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University College, London",
"sponsor_slug": "university-college-london",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07090005",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07090005",
"title": "Comparing the Efficacy and Safety of the EndoZipTM System and Apollo Endoscopic Sleeve Gastroplasty (ESG), Followed by Behavioral Modifications, in Obese Patients Who Have Not Achieved Weight Reduction Through Non-surgical Methods.",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Nitinotes Surgical Ltd.",
"sponsor_slug": "nitinotes-surgical-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07094685",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07094685",
"title": "A Phase II Study Evaluating Neoadjuvant Ivonescimab for Resectable Head and Neck Cancer",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06710431",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06710431",
"title": "A Double-blind, Placebo-controlled, Phase IIA Human Laboratory Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Afasci Inc",
"sponsor_slug": "afasci-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07056699",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07056699",
"title": "Protocol V: San Antonio Site Sub Study: Can Pioglitazone Block SGLT2 Inhibitor-induced Stimulation of Lipolysis, Ketone Production and Liver Glucose Production in Type I Diabetic Patients",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07032727",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07032727",
"title": "Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations",
"has_exemption": false,
"start_date": "2025-12-03",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05263206",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05263206",
"title": "Master Protocol of Two Randomized, Double Blind, Placebo-controlled, Multi-center, Parallel Group Studies to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Chronic Pruritus of Unknown Origin (CPUO)",
"has_exemption": false,
"start_date": "2022-02-15",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06401356",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06401356",
"title": "An Open-Label, Multicenter, Extension Study for Patients Previously Enrolled in Studies With Pelabresib",
"has_exemption": false,
"start_date": "2024-08-13",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04679844",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04679844",
"title": "A Prospective, Randomized, Multi-Center Study to Assess the Safety and Performance of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers (DBX or Grafton) Mixed With Local Autograft in Patients Undergoing One to Two-Level Instrumented Posterolateral Lumbar/Thoracolumbar Fusion (PLF)",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Kuros Biosurgery AG",
"sponsor_slug": "kuros-biosurgery-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06140836",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06140836",
"title": "Randomized, Open-label, Multicenter, Phase 3 Trial of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)",
"has_exemption": false,
"start_date": "2023-12-21",
"completion_date": "2027-06-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06847867",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06847867",
"title": "A Phase 2, Randomized, Open-label, Study of Momelotinib in Participants With Anemia Due to Low-risk Myelodysplastic Syndrome",
"has_exemption": false,
"start_date": "2025-06-05",
"completion_date": "2027-06-03",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06962306",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06962306",
"title": "Perioperative Methadone Use for Cleft Palate Repair: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2027-06-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05934448",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05934448",
"title": "A Phase II Trial of Pembrolizumab in Combination With Chimeric Antigen Receptor Therapy in Patients With Relapsed/Refractory Primary Mediastinal B-cell Lymphoma",
"has_exemption": false,
"start_date": "2023-11-15",
"completion_date": "2027-06-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Jennifer Crombie, MD",
"sponsor_slug": "jennifer-crombie-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06653192",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06653192",
"title": "Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction: An Open-label, Multicenter Randomized Trial (CARPEDIEM Trial)",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2027-06-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital Universitari de Bellvitge",
"sponsor_slug": "hospital-universitari-de-bellvitge",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06183931",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06183931",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Amyloid Depleter ALXN2220 in Adult Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2024-01-11",
"completion_date": "2027-06-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Alexion Pharmaceuticals, Inc.",
"sponsor_slug": "alexion-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06408935",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06408935",
"title": "A Phase 3b, Open-label, Multicenter Study to Evaluate Transmural Healing and Disease Modifying Effect of Guselkumab in Crohn's Disease Patients",
"has_exemption": false,
"start_date": "2024-04-17",
"completion_date": "2027-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen-Cilag Ltd.",
"sponsor_slug": "janssen-cilag-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06227910",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06227910",
"title": "A Randomized, Double-Blind, Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab and Oral Placebo for Induction Followed by Intravenous Vedolizumab Monotherapy for Maintenance in the Treatment of Adults With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2025-01-02",
"completion_date": "2027-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02584933",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02584933",
"title": "An Open-label, Multi-center, Phase IV Roll-over Study in Patients With ALK Positive Malignancies Who Have Completed a Novartis-sponsored Ceritinib (LDK378) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Ceritinib",
"has_exemption": false,
"start_date": "2015-12-11",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05477563",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05477563",
"title": "A Phase 3b Study to Evaluate Efficacy and Safety of a Single Dose of Autologous CRISPR Cas9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells (CTX001) in Subjects With Transfusion-Dependent β-Thalassemia or Severe Sickle Cell Disease",
"has_exemption": false,
"start_date": "2022-08-02",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05912244",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05912244",
"title": "A Phase II Study of IO102/IO103 and Nivolumab-relatlimab Fixed Dose Combination in Untreated, Unresectable Stage III/IV Melanoma",
"has_exemption": false,
"start_date": "2023-06-09",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06307652",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06307652",
"title": "A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared With Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients With Heart Failure and Impaired Kidney Function",
"has_exemption": false,
"start_date": "2024-04-12",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05067790",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05067790",
"title": "A Phase 3b Study to Evaluate Higher Dose Nusinersen (BIIB058) in Patients With Spinal Muscular Atrophy Previously Treated With Risdiplam",
"has_exemption": false,
"start_date": "2022-01-21",
"completion_date": "2027-06-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07012031",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07012031",
"title": "A Phase I/II Study Evaluating the Safety, Tolerability, and Efficacy of Sotorasib Plus Trastuzumab Deruxtecan in Patients With Advanced Non-Small Cell Lung Cancer With a KRASG12C Mutation",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-06-14",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06047535",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06047535",
"title": "Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First Complete Response. A Single-Arm, Multicenter Clinical Trial",
"has_exemption": false,
"start_date": "2023-10-31",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "SciClone Pharmaceuticals",
"sponsor_slug": "sciclone-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06333509",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06333509",
"title": "A Phase 1/2 Open Label Study to Evaluate the Safety and Efficacy of CT071, an Autologous Anti-GPRC5D CAR T, in Relapsed/Refractory Multiple Myeloma (RRMM) or Relapsed/Refractory Primary Plasma Cell Leukemia (RRpPCL)",
"has_exemption": false,
"start_date": "2024-04-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "CARsgen Therapeutics Co., Ltd.",
"sponsor_slug": "carsgen-therapeutics-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06305715",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06305715",
"title": "Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06422923",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06422923",
"title": "A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Temporal Lobe Epilepsy (MTLE)",
"has_exemption": false,
"start_date": "2024-11-14",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurona Therapeutics",
"sponsor_slug": "neurona-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06517797",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06517797",
"title": "Phase IIb Placebo-Controlled Double-Blind Randomized Parallel Groups Study to Determine the Efficacy and Safety of S1B-509 for Weight Loss",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "S1 Biopharma, Inc.",
"sponsor_slug": "s1-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06282042",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06282042",
"title": "Early Transcatheter Mitral Valve Repair After Myocardial Infarction",
"has_exemption": false,
"start_date": "2024-06-17",
"completion_date": "2027-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Fundación para la Investigación Biosanitaria del Principado de Asturias",
"sponsor_slug": "fundacion-para-la-investigacion-biosanitaria-del-principado-de-asturias",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06620523",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06620523",
"title": "Efficacy of Mitochondrial Directed Therapy in Prevention of Cardiac Surgery Associated AKI Prevent Cardiac Surgery Associated AKI Trial (Prevent CSA-AKI Trial)",
"has_exemption": false,
"start_date": "2024-07-18",
"completion_date": "2027-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "George Washington University",
"sponsor_slug": "george-washington-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06980077",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06980077",
"title": "UCLA L-11: A Phase II Trial of Ivonescimab for Previously Treated Thymic Carcinoma",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2027-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05758545",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05758545",
"title": "Concurrent Optical and Magnetic Stimulation (COMS) for Treatment of Refractory Diabetic Foot Ulcer; a Prospective Randomized, Sham-controlled, Double-blinded, Pivotal Clinical Trial",
"has_exemption": false,
"start_date": "2023-06-19",
"completion_date": "2027-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Piomic Medical",
"sponsor_slug": "piomic-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05422534",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05422534",
"title": "Role of Mitochondrial Dysfunction in the Response to Exercise in Patients with Advance Kidney Disease",
"has_exemption": false,
"start_date": "2023-06-01",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06598007",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06598007",
"title": "A Phase 1/2a First-In-Human, Open-Label, Multicenter, Dose Escalation and Dose Expansion Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CT3001 in Patients with Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2024-09-20",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Crossignal Therapeutics, Inc.",
"sponsor_slug": "crossignal-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02899052",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02899052",
"title": "A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2017-01-19",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04998552",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04998552",
"title": "Safety and Efficacy of Cyberknife in Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma: Open Label Prospective Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Capital Health System, Inc",
"sponsor_slug": "capital-health-system-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05126277",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05126277",
"title": "A Randomized, Double-blind, Parallel Group, Placebo-controlled, Multicenter Phase 3 Trial to Evaluate Efficacy, Safety and Tolerability of Ianalumab on Top of Standard-of-care Therapy in Participants With Active Lupus Nephritis (SIRIUS-LN).",
"has_exemption": false,
"start_date": "2022-07-14",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06995352",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06995352",
"title": "Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery: A Randomized, Observer and Participant Masked, Active Control, Non-Inferiority Study",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03731260",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03731260",
"title": "A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indolent and Smoldering Systemic Mastocytosis With Symptoms Inadequately Controlled With Standard Therapy",
"has_exemption": false,
"start_date": "2019-04-16",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Blueprint Medicines Corporation",
"sponsor_slug": "blueprint-medicines-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05445609",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05445609",
"title": "A Single Arm Study of Vidutolimod (CMP-001) With Nivolumab in Patients With Metastatic Castration Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2023-06-07",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06638138",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06638138",
"title": "A Multi-center, Prospective, Blinded, Randomized Study of Artelon FLEXBAND® for Patients Undergoing Soft Tissue Reconstruction of the Anterior Talofibular Ligament (ATFL) to Treat Lateral Ankle Instability",
"has_exemption": false,
"start_date": "2023-08-22",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Stryker Trauma and Extremities",
"sponsor_slug": "stryker-trauma-and-extremities",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03523975",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03523975",
"title": "Phase I/II Multi-site Study Evaluating the MTD, Safety and Efficacy of the Combination Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2018-12-24",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04994717",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04994717",
"title": "Phase 3 Randomized, Controlled Study of Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia With Safety Run-in (Golden Gate Study)",
"has_exemption": false,
"start_date": "2021-11-02",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06147986",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06147986",
"title": "A Phase IIa, Dose-Escalation Followed by Randomized, Open-Label, Parallel-Group Study to Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells As an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients",
"has_exemption": false,
"start_date": "2023-09-24",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Ever Supreme Bio Technology Co., Ltd.",
"sponsor_slug": "ever-supreme-bio-technology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06932263",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06932263",
"title": "A Phase IIb, Multicentre, Double-blind, Placebo-controlled Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adult Participants With Uncontrolled Asthma on Medium-to High Dose Inhaled Corticosteroids",
"has_exemption": false,
"start_date": "2025-03-26",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05949684",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05949684",
"title": "A Phase 3, Open-label, Randomized Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) vs Epoetin Alfa for the Treatment of Anemia Due to Revised International Prognostic Scoring System (IPSS-R) Very Low, Low, or Intermediate-Risk Myelodysplastic Syndrome (MDS) in Erythropoiesis-Stimulating Agent (ESA)-Naive Participants Who Are Non-Transfusion Dependent (NTD): The \"ELEMENT-MDS\" Trial",
"has_exemption": false,
"start_date": "2023-10-24",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06433011",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06433011",
"title": "The RAPID - PE Study: RESCUE Advanced Protocol Without ICU Stay and no Lytic Drip - for the Treatment of Pulmonary Embolism",
"has_exemption": false,
"start_date": "2024-06-25",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Thrombolex, Inc.",
"sponsor_slug": "thrombolex-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07053345",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT07053345",
"title": "An Interventional, Open-label, Single Arm, Multicenter Study to Evaluate the Efficacy and Safety of Esketamine Nasal Spray in Korean Participants With Treatment-Resistant Depression(TRD)",
"has_exemption": false,
"start_date": "2025-06-09",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Korea, Ltd., Korea",
"sponsor_slug": "janssen-korea-ltd-korea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06418958",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06418958",
"title": "In Vivo Temperature Changes Caused by Exposure to Short- and Long-wavelengths",
"has_exemption": false,
"start_date": "2025-07-01",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06065449",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06065449",
"title": "A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases",
"has_exemption": false,
"start_date": "2024-01-24",
"completion_date": "2027-06-27",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03670966",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03670966",
"title": "A Phase I/II Study Evaluating Escalating Doses of 211At-Labeled Anti-CD45 MAb BC8-B10 (211At-BC8-B10) Followed by Related Haplo-Identical Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Leukemia or Myelodysplastic Syndrome (MDS)",
"has_exemption": true,
"start_date": "2019-07-10",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06045754",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06045754",
"title": "An Open-Label, Phase 4 Study to Evaluate the Efficacy and Safety of Dual Targeted Therapy With Vedolizumab Intravenous (IV) and Adalimumab Subcutaneous (SC) or Vedolizumab IV and Ustekinumab IV/SC in Moderate to Severe Crohn's Disease (CD)",
"has_exemption": false,
"start_date": "2024-04-18",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03190941",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03190941",
"title": "A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients",
"has_exemption": false,
"start_date": "2017-09-21",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06077877",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06077877",
"title": "A Phase 1/2 First-Time-in-Human, Open-label, Multicenter, Dose Escalation and Expansion Study of the Oral DNA Polymerase Theta Inhibitor (POLQi) GSK4524101 and the PARP Inhibitor (PARPi) Niraparib in Adult Participants With Solid Tumors",
"has_exemption": false,
"start_date": "2023-10-24",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00412594",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT00412594",
"title": "Phase II Study of 2-Chlorodeoxyadenosine (2CDA) Followed by Rituximab in Hairy Cell Leukemia",
"has_exemption": false,
"start_date": "2004-06-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT00950430",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT00950430",
"title": "Brain Amyloid Imaging With Pittsburgh Compound B in Normal Aging, Mild Cognitive Impairment, and Dementia",
"has_exemption": false,
"start_date": "2008-04-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02427620",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02427620",
"title": "A Phase II Study of Ibrutinib Plus Rituximab With Hyper-CVAD Consolidation in Newly Diagnosed Young Patients With Mantle Cell Lymphoma: A Window Period for Bioimmunotherapy Before Chemotherapy",
"has_exemption": false,
"start_date": "2015-06-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02392442",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02392442",
"title": "Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in Humans",
"has_exemption": false,
"start_date": "2015-06-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institutes of Health Clinical Center (CC)",
"sponsor_slug": "national-institutes-of-health-clinical-center-cc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02494700",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02494700",
"title": "Ultra Low Dose 4 Gy Orbital Radiation for Definitive Therapy of Indolent B Cell Lymphoma",
"has_exemption": false,
"start_date": "2015-07-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02945501",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02945501",
"title": "Transcranial Electrical Stimulation at Slow Oscillation Frequency During NREM Sleep: An Assessment of Effects on the Restorative Properties of Sleep",
"has_exemption": false,
"start_date": "2016-10-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "U.S. Army Medical Research and Development Command",
"sponsor_slug": "us-army-medical-research-and-development-command",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02649166",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02649166",
"title": "Closing the Loop on Tremor: A Responsive Deep Brain Stimulator for the Treatment of Essential Tremor",
"has_exemption": false,
"start_date": "2017-02-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02942368",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02942368",
"title": "Adaptive Transcranial Direct Current Stimulation as an Adjunctive Therapy for Treatment-Resistant Major Depressive Disorder",
"has_exemption": false,
"start_date": "2017-04-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03067181",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03067181",
"title": "A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors",
"has_exemption": false,
"start_date": "2017-05-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03265431",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03265431",
"title": "Evaluation of PET/MR in Patients Selected for Ablation Therapy",
"has_exemption": false,
"start_date": "2017-07-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03128034",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03128034",
"title": "A Study Evaluating Escalating Doses of 211^At-Labeled Anti-CD45 MAb BC8-B10 (211^At-BC8-B10) Followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS)",
"has_exemption": true,
"start_date": "2017-10-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02724579",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02724579",
"title": "A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients",
"has_exemption": false,
"start_date": "2017-11-17",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03457493",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03457493",
"title": "UAB Neuroinflammation in Parkinson's Disease - TSPO-PET Substudy",
"has_exemption": false,
"start_date": "2018-03-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03191149",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03191149",
"title": "Phase II Study of Osimertinib (AZD9291) in Advanced NSCLC Patients With Exon 20 Insertion Mutations in EGFR",
"has_exemption": false,
"start_date": "2018-04-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03237780",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03237780",
"title": "A Randomized, Phase 2 Trial to Evaluate the Safety and Efficacy of Eribulin Mesylate in Combination With Atezolizumab Compared to Atezolizumab Alone in Subjects With Locally Advanced or Metastatic Transitional Cell Urothelial Cancer Where Cisplatin-Based Treatment is Not an Option",
"has_exemption": false,
"start_date": "2018-07-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03588975",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03588975",
"title": "A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee",
"has_exemption": false,
"start_date": "2018-10-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vericel Corporation",
"sponsor_slug": "vericel-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03617718",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03617718",
"title": "Methods to Identify and Treat Severe Asthma Patients Project 2: Airway pH Phenotyping",
"has_exemption": false,
"start_date": "2018-11-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Case Western Reserve University",
"sponsor_slug": "case-western-reserve-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03553875",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03553875",
"title": "Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions: A Randomized-controlled Trial",
"has_exemption": false,
"start_date": "2018-11-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03530852",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03530852",
"title": "A 90 Day, Phase 3, Open Labeled Exploratory Study of RELiZORB to Evaluate Safety, Tolerability, and Nutrient Absorption in Children With Short Bowel Syndrome Who Are Dependent on Parenteral Nutrition",
"has_exemption": false,
"start_date": "2018-11-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03550391",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03550391",
"title": "A Phase III Trial of Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases",
"has_exemption": false,
"start_date": "2018-11-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03739502",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03739502",
"title": "A Randomized Phase II Study Evaluating the Efficacy of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2019-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03960840",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03960840",
"title": "Phase I/II, Open Label, Multicenter Study of Rapcabtagene Autoleucel in Adult Patients With CLL/SLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL",
"has_exemption": false,
"start_date": "2019-06-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03878459",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03878459",
"title": "Can Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify the Decrease in HbA1c and Prevent the Increase in Plasma Ketone Concentration?",
"has_exemption": false,
"start_date": "2019-08-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03897127",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03897127",
"title": "Randomized Phase III Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics",
"has_exemption": false,
"start_date": "2019-09-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Ulm",
"sponsor_slug": "university-of-ulm",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03847467",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03847467",
"title": "Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in Pediatric and Young Adult IBD Patients Receiving Stable Maintenance Anti-TNF Therapy",
"has_exemption": false,
"start_date": "2019-09-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03969329",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03969329",
"title": "Phase 3, Single-arm, Open-label, Multidose, Titration, Pharmacokinetic, Pharmacodynamic, and Safety Study of Etelcalcetide in Children and Adolescents ≥ 2 to < 18 Years of Age With Secondary Hyperparathyroidism and Chronic Kidney Disease Receiving Maintenance Hemodialysis",
"has_exemption": false,
"start_date": "2019-12-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04298723",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04298723",
"title": "Randomized Comparison of Interventional Closure of the Left Atrial Appendage Using a LAA Closure Device Versus Oral Anticoagulation Therapy in Patients With Non-valvular Atrial Fibrillation and Status Post Intracranial Bleeding.",
"has_exemption": false,
"start_date": "2020-06-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jena University Hospital",
"sponsor_slug": "jena-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04307576",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04307576",
"title": "ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) With Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL)",
"has_exemption": false,
"start_date": "2020-07-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mats Heyman",
"sponsor_slug": "mats-heyman",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04189757",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04189757",
"title": "A Phase II Study of Acalabrutinib in Ibrutinib-Intolerant Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2020-08-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04505254",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04505254",
"title": "Intermittent Therapy With the BTK Inhibitor Acalabrutinib (Calquence) in Combination With Obinutuzumab in Treatment Naive (Tn) Patients With Chronic Lymphocytic Leukemia (CLL)",
"has_exemption": false,
"start_date": "2020-08-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04511013",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04511013",
"title": "A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases",
"has_exemption": false,
"start_date": "2021-01-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04786262",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04786262",
"title": "A Phase 1/2/3 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus With Impaired Hypoglycemic Awareness and Severe Hypoglycemia",
"has_exemption": false,
"start_date": "2021-03-29",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04885322",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04885322",
"title": "Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands",
"has_exemption": false,
"start_date": "2021-04-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04085406",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04085406",
"title": "Deep Brain Stimulation of the Subgenual Cingulate Cortex for the Treatment of Medically Refractory Chronic Low Back Pain",
"has_exemption": false,
"start_date": "2021-05-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04856085",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04856085",
"title": "A Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of Regimens Containing VIR-2218, VIR-3434, And/or PEG-IFNα in Subjects with Chronic Hepatitis B Virus Infection",
"has_exemption": false,
"start_date": "2021-07-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vir Biotechnology, Inc.",
"sponsor_slug": "vir-biotechnology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04554914",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04554914",
"title": "An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety of Tabelecleucel in Subjects With Epstein-Barr Virus-associated Diseases (EBVision)",
"has_exemption": false,
"start_date": "2021-07-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Atara Biotherapeutics",
"sponsor_slug": "atara-biotherapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04911816",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04911816",
"title": "Phase I/II Study of Neoadjuvant mFOLFIRINOX in Combination With Peri-operative Oral Hydroxychloroquine (FHQ) in Subjects With Resectable Adenocarcinoma of the Pancreas.",
"has_exemption": false,
"start_date": "2021-07-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "West Virginia University",
"sponsor_slug": "west-virginia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03324529",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03324529",
"title": "Autonomic Modulation in Takotsubo Syndrome",
"has_exemption": false,
"start_date": "2021-10-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04919226",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04919226",
"title": "A Prospective, Randomised, Controlled, Open-label, Multicentre Study to Evaluate Efficacy, Safety and Patient-Reported Outcomes of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-Edotreotide Compared to Best Standard of Care in Patients With Well-differentiated Aggressive Grade 2 and Grade 3, Somatostatin Receptor-Positive (SSTR+), Neuroendocrine Tumours of GastroEnteric or Pancreatic Origin",
"has_exemption": false,
"start_date": "2021-12-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ITM Solucin GmbH",
"sponsor_slug": "itm-solucin-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05386277",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05386277",
"title": "A Post Market Clinical Study to Confirm the Performance and Safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter on Patients Undergoing Surgical Treatment for the Removal of Arterial Emboli and/or Thrombi",
"has_exemption": false,
"start_date": "2022-01-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "LeMaitre Vascular",
"sponsor_slug": "lemaitre-vascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04743505",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04743505",
"title": "Phase I/II Study Exploring the Safety and Efficacy of Combining APL-101 With Frontline Osimertinib in Patients With EGFR-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2022-01-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05185843",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05185843",
"title": "An Open-Label Safety Study of AKCEA-APOCIII-LRX Administered Subcutaneously to Patients With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen (ISIS 304801)",
"has_exemption": false,
"start_date": "2022-02-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05591547",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05591547",
"title": "SH APBI RISE: Evaluating the Safety and Efficacy of a Novel IMRT/VMAT-based Accelerated Partial Breast Irradiation Regimen for PatIents with Favorable Risk BreaSt CancEr",
"has_exemption": false,
"start_date": "2022-03-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanford Health",
"sponsor_slug": "sanford-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05444452",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05444452",
"title": "Comparison Between Abluminal Biodegradable Polymer Ultrathin Sirolimus-eluting Stent and Durable-polymer Everolimus-eluting Stent (GENOSS Randomized Clinical Trial)",
"has_exemption": false,
"start_date": "2022-04-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Samsung Medical Center",
"sponsor_slug": "samsung-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05604170",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05604170",
"title": "A Phase 3, Open-label Study of Adjunctive Ganaxolone (GNX) Treatment in Children and Adults With Tuberous Sclerosis Complex (TSC)-Related Epilepsy (TrustTSC OLE)",
"has_exemption": false,
"start_date": "2022-05-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Marinus Pharmaceuticals",
"sponsor_slug": "marinus-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05416307",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05416307",
"title": "A Multipart, Open-label, Single-arm, Multicenter Study to Evaluate the Safety, Efficacy and Pharmacokinetics of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Electra Therapeutics Inc.",
"sponsor_slug": "electra-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05099003",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05099003",
"title": "A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG)",
"has_exemption": false,
"start_date": "2022-05-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285553",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05285553",
"title": "MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms",
"has_exemption": false,
"start_date": "2022-06-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Coopervision, Inc.",
"sponsor_slug": "coopervision-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05172258",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05172258",
"title": "A Phase 2 Study of Ipatasertib in Combination With Pembrolizumab for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck",
"has_exemption": false,
"start_date": "2022-07-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285878",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05285878",
"title": "A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation",
"has_exemption": false,
"start_date": "2022-07-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05479981",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05479981",
"title": "A Phase 2 Extension Study to Evaluate the Long-Term Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of AOC 1001 Administered Intravenously to Adult Myotonic Dystrophy Type 1 (DM1) Patients",
"has_exemption": false,
"start_date": "2022-08-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Avidity Biosciences, Inc.",
"sponsor_slug": "avidity-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04646226",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04646226",
"title": "A Randomized Trial of Fistula vs. Graft Arteriovenous Vascular Access in Older Adults With End-Stage Kidney Disease on Hemodialysis",
"has_exemption": false,
"start_date": "2022-08-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05188183",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05188183",
"title": "Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response",
"has_exemption": false,
"start_date": "2022-09-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Spaulding Rehabilitation Hospital",
"sponsor_slug": "spaulding-rehabilitation-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564091",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05564091",
"title": "Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma",
"has_exemption": false,
"start_date": "2022-09-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nova Eye, Inc.",
"sponsor_slug": "nova-eye-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05381597",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05381597",
"title": "Combination of 5-Fluorouracil and Calcipotriene in the Treatment of Superficial Basal Cell Carcinomas and Squamous Cell Carcinomas in Situ",
"has_exemption": false,
"start_date": "2022-10-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston University",
"sponsor_slug": "boston-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06128720",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT06128720",
"title": "A Randomized, Sham Controlled, Masked Phase II Study to Evaluate the Neuroprotective Effect of Hyperbaric Oxygen Therapy on Optic Neuropathy",
"has_exemption": false,
"start_date": "2022-11-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05639907",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05639907",
"title": "A Comparison of Miniscrew Stability and Peri-implant Inflammation When Precoated With Antimicrobial Quaternary Ammonium Compound K21 vs Ethanol Control in Orthodontic Patients: a Triple-blind, Split-mouth, Randomized Controlled Clinical Trial",
"has_exemption": false,
"start_date": "2022-11-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05518903",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05518903",
"title": "Quantitative In Vivo 68Ga-Fibroblast-Activation-Protein-Inhibitors (FAPI)-46 PET Imaging of Cancer-Associated Fibroblasts (CAFs) in Pancreatic Ductal Adenocarcinoma (PDA)",
"has_exemption": false,
"start_date": "2022-11-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05579366",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05579366",
"title": "Phase 1/2 Study of Rina-S in Patients With Locally Advanced and/or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2022-12-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05633654",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05633654",
"title": "A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy",
"has_exemption": false,
"start_date": "2022-12-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05198830",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05198830",
"title": "A Phase 2 Randomized Study of the BER Inhibitor TRC102 in Combination With Standard Pemetrexed-Platinum-Radiation in Stage III Non-Squamous Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2022-12-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05674825",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05674825",
"title": "An Open-label, Navigational Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses",
"has_exemption": false,
"start_date": "2022-12-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05396105",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05396105",
"title": "A Phase II/III, Extension Study of Orally Administered PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema",
"has_exemption": false,
"start_date": "2022-12-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharvaris Netherlands B.V.",
"sponsor_slug": "pharvaris-netherlands-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05386342",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05386342",
"title": "A Post-market Clinical Study to Confirm the Performance and Safety of the LeMaitre TufTex Over-the-Wire (OTW) Embolectomy Catheter on Patients Undergoing Surgical Treatment for the Removal of Arterial Emboli and/or Thrombi",
"has_exemption": false,
"start_date": "2023-01-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "LeMaitre Vascular",
"sponsor_slug": "lemaitre-vascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05173324",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05173324",
"title": "Integration of HPV Vaccination and HPV-based Cervical Screening in Young Adult WLWH Into ARV Clinics to Speed the Pathway Towards Cervical Cancer Elimination: the H2VICTORY Trial",
"has_exemption": false,
"start_date": "2023-02-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "International Agency for Research on Cancer",
"sponsor_slug": "international-agency-for-research-on-cancer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05896293",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05896293",
"title": "Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders",
"has_exemption": false,
"start_date": "2023-02-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stephanie B. Seminara, MD",
"sponsor_slug": "stephanie-b-seminara-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05578976",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05578976",
"title": "A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)",
"has_exemption": false,
"start_date": "2023-02-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05651022",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05651022",
"title": "A Phase 1/2, Open-Label, Multi-Center, Dose Escalation and Expansion Study Evaluating the Safety, Tolerability and Clinical Activity of DECOY20 as Monotherapy and in Combination With Tislelizumab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indaptus Therapeutics, Inc",
"sponsor_slug": "indaptus-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05570812",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05570812",
"title": "In Vivo Targeting of Neuroactive Steroid and Immune Networks for Depression in People Living With HIV",
"has_exemption": false,
"start_date": "2023-03-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05706129",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05706129",
"title": "A Multicenter, Open-Label, Non-Randomized Phase 1/2 Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Patients With Unresectable Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2023-03-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Debiopharm International SA",
"sponsor_slug": "debiopharm-international-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05432804",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05432804",
"title": "A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2023-03-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05741333",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05741333",
"title": "Pivotal In-Office Clinical Study of the Solo+ Tympanostomy Tube Device",
"has_exemption": false,
"start_date": "2023-03-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AventaMed DAC",
"sponsor_slug": "aventamed-dac",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05752071",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05752071",
"title": "GaStrointestinal STIMULation As a Treatment of Postoperative IlEus Following Extensive Surgery (STIMULATE). -A Prospective Double-blinded Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2023-04-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Aarhus",
"sponsor_slug": "university-of-aarhus",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05759988",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05759988",
"title": "Cervical Ripening as an Outpatient Method Using the Foley: a Randomized Trial",
"has_exemption": false,
"start_date": "2023-04-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05918835",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05918835",
"title": "Deciphering the Neural Mechanisms of Restrictive Eating in Anorexia Nervosa Using Repetitive Transcranial Magnetic Stimulation",
"has_exemption": false,
"start_date": "2023-04-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "New York State Psychiatric Institute",
"sponsor_slug": "new-york-state-psychiatric-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05483465",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05483465",
"title": "Effects of NAD Restoration on Neurovascular Coupling in Community Dwelling Older Adults",
"has_exemption": false,
"start_date": "2023-05-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05864144",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05864144",
"title": "A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SNS-101 (Anti VISTA) as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sensei Biotherapeutics, Inc.",
"sponsor_slug": "sensei-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05919797",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05919797",
"title": "Association of Genetic Variations and Weight Loss Response to Naltrexone/Bupropion",
"has_exemption": false,
"start_date": "2023-06-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05884125",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05884125",
"title": "Promoting Healing of Injured Nerves With Electrical Stimulation Therapy",
"has_exemption": false,
"start_date": "2023-06-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Checkpoint Surgical Inc.",
"sponsor_slug": "checkpoint-surgical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05351801",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05351801",
"title": "Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain",
"has_exemption": false,
"start_date": "2023-06-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05878769",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05878769",
"title": "A Phase III Open-Label Extension Study to Evaluate the Long-Term Safety of Astegolimab in Patients With Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2023-06-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}