HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 49216,
"recordsTotal": 49216,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=status&start=45900",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=status&start=45300",
"results": [
{
"registry_id": "NCT07509008",
"publication_url": "https://clinicaltrials.gov/study/NCT07509008",
"title": "Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07527169",
"publication_url": "https://clinicaltrials.gov/study/NCT07527169",
"title": "A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory Neuroblastoma",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2028-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04524247",
"publication_url": "https://clinicaltrials.gov/study/NCT04524247",
"title": "Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms With Physician-Modified Fenestrated and Branched Stent Grafts",
"has_exemption": false,
"start_date": "2021-02-23",
"completion_date": "2028-07-02",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05327023",
"publication_url": "https://clinicaltrials.gov/study/NCT05327023",
"title": "Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies",
"has_exemption": false,
"start_date": "2022-05-23",
"completion_date": "2028-07-03",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03768063",
"publication_url": "https://clinicaltrials.gov/study/NCT03768063",
"title": "An Open Label, Multicenter Extension Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella B)",
"has_exemption": false,
"start_date": "2019-02-28",
"completion_date": "2028-07-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03101917",
"publication_url": "https://clinicaltrials.gov/study/NCT03101917",
"title": "Microtable® Microstereotactic Frame and Drill Press and Associated Method for Cochlear Implantation",
"has_exemption": false,
"start_date": "2027-07-01",
"completion_date": "2028-07-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06006806",
"publication_url": "https://clinicaltrials.gov/study/NCT06006806",
"title": "Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy",
"has_exemption": false,
"start_date": "2023-07-07",
"completion_date": "2028-07-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Covenant Health Cancer Center",
"sponsor_slug": "covenant-health-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05693129",
"publication_url": "https://clinicaltrials.gov/study/NCT05693129",
"title": "An Open-label, Single Arm Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Leniolisib in Pediatric Patients (Aged 1 to 6 Years) With APDS (Activated Phosphoinositide 3-Kinase Delta Syndrome) Followed by an Open-label Long-term Extension",
"has_exemption": false,
"start_date": "2023-08-30",
"completion_date": "2028-07-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharming Technologies B.V.",
"sponsor_slug": "pharming-technologies-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226986",
"publication_url": "https://clinicaltrials.gov/study/NCT07226986",
"title": "A Phase Ib/II Open-label, Multi-center Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With an Androgen Receptor Pathway Inhibitor (ARPI) in Adult Participants With PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-12-05",
"completion_date": "2028-07-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05211895",
"publication_url": "https://clinicaltrials.gov/study/NCT05211895",
"title": "A Phase III, Randomised, Double-blind, Placebo-controlled, Multicentre, International Study of Durvalumab Plus Domvanalimab(AB154) in Participants With Locally Advanced (Stage III), Unresectable Non-small Cell Lung Cancer Whose Disease Has Not Progressed Following Definitive Platinum-based Concurrent Chemoradiation Therapy",
"has_exemption": false,
"start_date": "2022-02-18",
"completion_date": "2028-07-12",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07024563",
"publication_url": "https://clinicaltrials.gov/study/NCT07024563",
"title": "A Phase 3, Open-Label, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of Ravulizumab in Pediatric Participants (2 to < 18 Years of Age) With Primary Immunoglobulin A Nephropathy (IgAN)",
"has_exemption": false,
"start_date": "2025-06-14",
"completion_date": "2028-07-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Alexion Pharmaceuticals, Inc.",
"sponsor_slug": "alexion-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07571005",
"publication_url": "https://clinicaltrials.gov/study/NCT07571005",
"title": "Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure (AMAZE 3)",
"has_exemption": false,
"start_date": "2026-05-05",
"completion_date": "2028-07-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04738422",
"publication_url": "https://clinicaltrials.gov/study/NCT04738422",
"title": "Determining Airway pH by Compartmental Exhaled Nitric Oxide Levels During Alkaline Buffer Challenge",
"has_exemption": false,
"start_date": "2020-09-11",
"completion_date": "2028-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06325683",
"publication_url": "https://clinicaltrials.gov/study/NCT06325683",
"title": "Randomized Phase II Trial of Anti-Lag-3 and Anti-PD-1 Blockade vs. SOC in Patients With Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2024-11-08",
"completion_date": "2028-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05382091",
"publication_url": "https://clinicaltrials.gov/study/NCT05382091",
"title": "A Phase II Multi-Center Safety Study Examining the Use of the O'Neil Long Acting Naltrexone Implant (OLANI) in Opioid Dependent Persons Receiving Repeat Dosing",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2028-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Go Medical Industries Pty Ltd",
"sponsor_slug": "go-medical-industries-pty-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06575686",
"publication_url": "https://clinicaltrials.gov/study/NCT06575686",
"title": "A Phase 2 Study of Epcoritamab Plus Tazemetostat for Treatment of Relapsed/Refractory Follicular Lymphoma",
"has_exemption": false,
"start_date": "2025-03-11",
"completion_date": "2028-07-16",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05806138",
"publication_url": "https://clinicaltrials.gov/study/NCT05806138",
"title": "A Randomized Controlled Trial of the Soluble Guanylate Cyclase Stimulator Vericiguat in Patients With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction (ELEVATE)",
"has_exemption": false,
"start_date": "2023-07-17",
"completion_date": "2028-07-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07073820",
"publication_url": "https://clinicaltrials.gov/study/NCT07073820",
"title": "A PHASE 2, OPEN-LABEL EXTENSION STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF PF-07868489 ADMINISTERED TO ADULT PARTICIPANTS WITH PULMONARY ARTERIAL HYPERTENSION",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2028-07-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05976269",
"publication_url": "https://clinicaltrials.gov/study/NCT05976269",
"title": "The Effects of Bilateral Knee Pain & Dry Needling on Laterality Recognition, Movement, & Function",
"has_exemption": false,
"start_date": "2020-07-21",
"completion_date": "2028-07-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University",
"sponsor_slug": "ohio-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05935215",
"publication_url": "https://clinicaltrials.gov/study/NCT05935215",
"title": "A Multicenter, Single Arm, Open-label Study to Evaluate Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With aHUS",
"has_exemption": false,
"start_date": "2024-02-28",
"completion_date": "2028-07-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06570798",
"publication_url": "https://clinicaltrials.gov/study/NCT06570798",
"title": "A Phase 2, Open Label, Multicenter, Platform Trial to Assess the Safety, Tolerability, and Efficacy of Inebilizumab and Blinatumomab in Subjects With Autoimmune Diseases",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2028-07-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961006",
"publication_url": "https://clinicaltrials.gov/study/NCT06961006",
"title": "A Phase 2, Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Clinical Study of V940 (mRNA-4157) Plus Pembrolizumab Versus Placebo Plus Pembrolizumab in Participants With First-Line Advanced Melanoma (INTerpath-012)",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2028-07-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07351045",
"publication_url": "https://clinicaltrials.gov/study/NCT07351045",
"title": "A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 Administered to Participants With Obesity or Overweight Without Type 2 Diabetes",
"has_exemption": false,
"start_date": "2026-03-16",
"completion_date": "2028-07-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05888493",
"publication_url": "https://clinicaltrials.gov/study/NCT05888493",
"title": "A Randomized, Open-label, Multi-center Phase III Trial Comparing Tisagenlecleucel to Standard of Care in Adult Participants With Relapsed or Refractory Follicular Lymphoma (FL)",
"has_exemption": false,
"start_date": "2023-10-02",
"completion_date": "2028-07-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06330064",
"publication_url": "https://clinicaltrials.gov/study/NCT06330064",
"title": "A Phase 1B/2 Pan-Tumor, Open-Label Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)",
"has_exemption": false,
"start_date": "2024-04-10",
"completion_date": "2028-07-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07211685",
"publication_url": "https://clinicaltrials.gov/study/NCT07211685",
"title": "A Randomized, Double-blind, Placebo-controlled, Parallel Group Phase 2a Study With an Extension Phase to Evaluate the Efficacy and Safety of BAY 3401016 in Participants Aged 18 to 45 With Alport Syndrome",
"has_exemption": false,
"start_date": "2025-11-19",
"completion_date": "2028-07-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Bayer",
"sponsor_slug": "bayer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07489066",
"publication_url": "https://clinicaltrials.gov/study/NCT07489066",
"title": "AN INTERVENTIONAL, OPEN-LABEL, PHASE 2 STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF PF-08634404 MONOTHERAPY OR IN COMBINATION IN ADULT PARTICIPANTS WITH EARLY-STAGE RESECTABLE OR LOCALLY ADVANCED UNRESECTABLE NON-SMALL CELL LUNG CANCER",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2028-07-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05649956",
"publication_url": "https://clinicaltrials.gov/study/NCT05649956",
"title": "A Randomized Phase II Study of Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma",
"has_exemption": false,
"start_date": "2024-07-17",
"completion_date": "2028-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GOG Foundation",
"sponsor_slug": "gog-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06915441",
"publication_url": "https://clinicaltrials.gov/study/NCT06915441",
"title": "Lipid Infusions to Optimize Nutrition (LION) and Minimize Bronchopulmonary Dysplasia and Neurodevelopmental Impairment in Extremely Preterm Infants: A Randomized Comparative Effectiveness Trial",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2028-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07587658",
"publication_url": "https://clinicaltrials.gov/study/NCT07587658",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy of Dupilumab Added on to Standard of Care (SOC) Treatment vs SOC Treatment Following Hospitalization for a COPD Exacerbation",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07571343",
"publication_url": "https://clinicaltrials.gov/study/NCT07571343",
"title": "Fueling Labor: A Pilot Randomized Controlled Trial of High-Protein Supplementation During Labor to Improve Glucose Control in Insulin-Treated Diabetes Using Continuous Glucose Monitoring",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02130492",
"publication_url": "https://clinicaltrials.gov/study/NCT02130492",
"title": "A Pilot Study Treatment of Malignant Tumors Using [18F] Fluorodeoxyglucose (FDG)",
"has_exemption": false,
"start_date": "2014-05-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02051062",
"publication_url": "https://clinicaltrials.gov/study/NCT02051062",
"title": "Pharmacokinetics of Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) - (Equine) (BAT®) in Pediatric Patients With a Confirmed or Suspected Exposure to Botulinum Neurotoxin",
"has_exemption": false,
"start_date": "2014-10-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emergent BioSolutions",
"sponsor_slug": "emergent-biosolutions",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT04258943",
"publication_url": "https://clinicaltrials.gov/study/NCT04258943",
"title": "A Phase I/II Study of Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia\", Study ITCC-054/COG-AAML1921",
"has_exemption": false,
"start_date": "2020-07-06",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04488081",
"publication_url": "https://clinicaltrials.gov/study/NCT04488081",
"title": "I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients",
"has_exemption": false,
"start_date": "2020-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "QuantumLeap Healthcare Collaborative",
"sponsor_slug": "quantumleap-healthcare-collaborative",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04400266",
"publication_url": "https://clinicaltrials.gov/study/NCT04400266",
"title": "Buspirone and Melatonin for Depression Following Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2020-08-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04475705",
"publication_url": "https://clinicaltrials.gov/study/NCT04475705",
"title": "The Effects of Propofol Based Intravenous vs Sevoflurane Inhalation Anaesthesia on Inflammation and Circulating Tumor Cells in Paediatric Tumor Surgery - a Pilot Study",
"has_exemption": false,
"start_date": "2021-01-11",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hong Kong Children's Hospital",
"sponsor_slug": "hong-kong-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04278898",
"publication_url": "https://clinicaltrials.gov/study/NCT04278898",
"title": "Targeting the Neurobiology of Restricted and Repetitive Behaviors in Children With Autism Using N-acetylcysteine: a Single-dose Challenge Study",
"has_exemption": false,
"start_date": "2021-02-12",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04667585",
"publication_url": "https://clinicaltrials.gov/study/NCT04667585",
"title": "Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx Using Metabolic Signature From Interim 18FDG-PET/CT",
"has_exemption": false,
"start_date": "2021-04-12",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04140734",
"publication_url": "https://clinicaltrials.gov/study/NCT04140734",
"title": "Study Protocol for Comparison of Lower Eyelid Retraction Repair With Hard Palate, Autologous Ear Cartilage, and Porcine Acellular Dermal Matrix Spacer Grafts",
"has_exemption": false,
"start_date": "2021-08-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05152823",
"publication_url": "https://clinicaltrials.gov/study/NCT05152823",
"title": "Phase I/IIa Intrathecal Gene Delivery Clinical Trial for IGHMBP2-Related Diseases",
"has_exemption": false,
"start_date": "2021-11-04",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Megan Waldrop",
"sponsor_slug": "megan-waldrop",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03750825",
"publication_url": "https://clinicaltrials.gov/study/NCT03750825",
"title": "Are Smokers Switching to Vaping at Lower Risk for Cancer?",
"has_exemption": false,
"start_date": "2021-12-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04430452",
"publication_url": "https://clinicaltrials.gov/study/NCT04430452",
"title": "Phase II Trial of Durvalumab (MEDI4736) With/Without Tremelimumab for Advanced Hepatocellular Carcinoma After Palliative Hypofractionated Radiotherapy",
"has_exemption": false,
"start_date": "2022-02-04",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mary Feng, MD",
"sponsor_slug": "mary-feng-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05100862",
"publication_url": "https://clinicaltrials.gov/study/NCT05100862",
"title": "A Phase 3 Randomized, Open-Label Multicenter Study of Zanubrutinib (BGB-3111) Plus Anti-CD20 Antibodies Versus Lenalidomide Plus Rituximab in Patients With Relapsed/Refractory Follicular or Marginal Zone Lymphoma",
"has_exemption": false,
"start_date": "2022-03-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05382299",
"publication_url": "https://clinicaltrials.gov/study/NCT05382299",
"title": "A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Do Not Express PD-L1 or in Patients Previously Treated With Anti-PD-(L)1 Agents in the Early Setting Whose Tumors Do Express PD-L1",
"has_exemption": false,
"start_date": "2022-07-20",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05462093",
"publication_url": "https://clinicaltrials.gov/study/NCT05462093",
"title": "Clinical Application of Annual Liver Multiscan and MRCP+ in Primary Sclerosing Cholangitis: the CATCH-IT Study",
"has_exemption": false,
"start_date": "2022-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)",
"sponsor_slug": "academisch-medisch-centrum-universiteit-van-amsterdam-amc-uva",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05223803",
"publication_url": "https://clinicaltrials.gov/study/NCT05223803",
"title": "Phase 2 Randomized Total Eradication of Metastatic Lesions Following Definitive Radiation to the Prostate in de Novo oligometaStatic Prostate Cancer (TERPS) Trial",
"has_exemption": false,
"start_date": "2022-10-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05469737",
"publication_url": "https://clinicaltrials.gov/study/NCT05469737",
"title": "A Phase 2/3, Multicenter, Randomized, Dose Optimization (Part I), Double-blind (Part II) Study to Compare the Efficacy and Safety of Oral Azacitidine (Oral-Aza, ONUREG®) Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Participants With IPSS-R Low- or Intermediate-risk Myelodysplastic Syndrome (MDS)",
"has_exemption": false,
"start_date": "2022-12-14",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04782258",
"publication_url": "https://clinicaltrials.gov/study/NCT04782258",
"title": "A Phase 3b Multicenter Open-label Trial of the Safety, Tolerability, and Efficacy of Tolvaptan in Infants and Children 28 Days to Less Than 18 Years of Age With Autosomal Recessive Polycystic Kidney Disease (ARPKD)",
"has_exemption": false,
"start_date": "2023-01-23",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
"sponsor_slug": "otsuka-pharmaceutical-development-commercialization-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05520567",
"publication_url": "https://clinicaltrials.gov/study/NCT05520567",
"title": "A Phase 1/2, Multicenter, Open-Label, Randomized Dose Ranging and Expansion Study of the Combination of Gilteritinib, Venetoclax and Azacitidine in Patients With Newly Diagnosed FLT3 Mutated Acute Myeloid Leukemia (AML) Not Eligible for Intensive Induction Chemotherapy",
"has_exemption": false,
"start_date": "2023-01-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05704647",
"publication_url": "https://clinicaltrials.gov/study/NCT05704647",
"title": "Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases",
"has_exemption": false,
"start_date": "2023-02-23",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05408845",
"publication_url": "https://clinicaltrials.gov/study/NCT05408845",
"title": "A Phase II Trial of HER2-Targeted Therapies for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers",
"has_exemption": false,
"start_date": "2023-03-03",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NRG Oncology",
"sponsor_slug": "nrg-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05599022",
"publication_url": "https://clinicaltrials.gov/study/NCT05599022",
"title": "Randomized Assessment of the Efficacy of Transcutaneous Magnetic Stimulation in Patients With Ventricular Tachycardia Storm",
"has_exemption": false,
"start_date": "2023-05-22",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05884320",
"publication_url": "https://clinicaltrials.gov/study/NCT05884320",
"title": "Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancers",
"has_exemption": false,
"start_date": "2023-07-27",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05618353",
"publication_url": "https://clinicaltrials.gov/study/NCT05618353",
"title": "Impact of Colchicine on Peri-Operative Major Adverse Cardiovascular Events in Patients With Prior Coronary Revascularization",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05722938",
"publication_url": "https://clinicaltrials.gov/study/NCT05722938",
"title": "A Randomized, Placebo-controlled, Double-blind, Multi-center, Phase III Trial to Assess the Efficacy and Safety of Trimodulin (BT588) in Adult Hospitalized Subjects With Severe Community-acquired Pneumonia (sCAP)",
"has_exemption": false,
"start_date": "2023-09-09",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biotest",
"sponsor_slug": "biotest",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05854498",
"publication_url": "https://clinicaltrials.gov/study/NCT05854498",
"title": "Phase II Study of Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2023-10-13",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05885542",
"publication_url": "https://clinicaltrials.gov/study/NCT05885542",
"title": "Sex Differences in the Interface Between Cannabis Use and Stress Among Emerging Adults",
"has_exemption": false,
"start_date": "2023-11-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05422612",
"publication_url": "https://clinicaltrials.gov/study/NCT05422612",
"title": "A Phase 2, Multi-center, Multi-arm, Randomized, Placebo-controlled, Double-blind, Adaptive Platform Study to Evaluate the Safety, Tolerability, and Efficacy of Potential Pharmacotherapeutic Interventions in Active-Duty Service Members, Veterans, and Non-Veteran Civilians With PTSD",
"has_exemption": false,
"start_date": "2023-11-02",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Global Coalition for Adaptive Research",
"sponsor_slug": "global-coalition-for-adaptive-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05583617",
"publication_url": "https://clinicaltrials.gov/study/NCT05583617",
"title": "A Platform Study Evaluating the Safety and Efficacy of Multiple Treatments in Patients With Multiple Myeloma",
"has_exemption": false,
"start_date": "2023-11-14",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05437575",
"publication_url": "https://clinicaltrials.gov/study/NCT05437575",
"title": "Prehospital Analgesia INtervention Trial (PAIN)",
"has_exemption": false,
"start_date": "2023-11-27",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jason Sperry",
"sponsor_slug": "jason-sperry",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05460611",
"publication_url": "https://clinicaltrials.gov/study/NCT05460611",
"title": "A Pilot Study Evaluating the Safety and Efficacy of a 1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06154252",
"publication_url": "https://clinicaltrials.gov/study/NCT06154252",
"title": "A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy",
"has_exemption": false,
"start_date": "2023-12-20",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cabaletta Bio",
"sponsor_slug": "cabaletta-bio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06234748",
"publication_url": "https://clinicaltrials.gov/study/NCT06234748",
"title": "Pilot Phase II Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer",
"has_exemption": false,
"start_date": "2023-12-20",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06045247",
"publication_url": "https://clinicaltrials.gov/study/NCT06045247",
"title": "Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2024-01-05",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05781009",
"publication_url": "https://clinicaltrials.gov/study/NCT05781009",
"title": "Pregnenolone for the Treatment of Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2024-01-08",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06132477",
"publication_url": "https://clinicaltrials.gov/study/NCT06132477",
"title": "Biometabolic Impact of Continuation of GLP-1 Agonists Following Bariatric",
"has_exemption": false,
"start_date": "2024-02-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Missouri-Columbia",
"sponsor_slug": "university-of-missouri-columbia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06067737",
"publication_url": "https://clinicaltrials.gov/study/NCT06067737",
"title": "Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder: a Randomized Double-blind Trial",
"has_exemption": false,
"start_date": "2024-02-08",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05835037",
"publication_url": "https://clinicaltrials.gov/study/NCT05835037",
"title": "Clinical and Nutrigenetic Assessment of Zinc in Participants With Prediabetes",
"has_exemption": false,
"start_date": "2024-02-16",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05494398",
"publication_url": "https://clinicaltrials.gov/study/NCT05494398",
"title": "Targeting the Neurobiology of Restricted and Repetitive Behaviors in Children With Autism Using N-acetylcysteine: an Open Label Extension",
"has_exemption": false,
"start_date": "2024-03-12",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06285695",
"publication_url": "https://clinicaltrials.gov/study/NCT06285695",
"title": "Clareon Toric Single Arm Study (T2-T9)",
"has_exemption": false,
"start_date": "2024-04-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alcon Research",
"sponsor_slug": "alcon-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06234969",
"publication_url": "https://clinicaltrials.gov/study/NCT06234969",
"title": "A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation",
"has_exemption": false,
"start_date": "2024-04-29",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05952804",
"publication_url": "https://clinicaltrials.gov/study/NCT05952804",
"title": "Immunoglobulin Replacement Therapy and Infectious Complications After CD19-Targeted CAR-T-Cell Therapy",
"has_exemption": false,
"start_date": "2024-06-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06252675",
"publication_url": "https://clinicaltrials.gov/study/NCT06252675",
"title": "A Multicenter Phase 2 Study of Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06284590",
"publication_url": "https://clinicaltrials.gov/study/NCT06284590",
"title": "A Phase 2, Three-arm, Randomized Study of the Efficacy of Intratumorally Administered L19IL2 or L19TNF or L19IL2/L19TNF, All in Combination with Systemic Anti-PD1 Pembrolizumab, in Stage III and IV Unresectable Melanoma Patients with Resistance to or Progressing Upon Anti-PD1 Checkpoint Inhibitors and with Presence of Injectable Metastases",
"has_exemption": false,
"start_date": "2024-07-12",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Philogen S.p.A.",
"sponsor_slug": "philogen-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06529523",
"publication_url": "https://clinicaltrials.gov/study/NCT06529523",
"title": "PD-1 (Programmed Cell Death Protein 1) Blockade in Mismatch-repair Deficient Colorectal Cancer in Nigeria",
"has_exemption": false,
"start_date": "2024-07-26",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06413498",
"publication_url": "https://clinicaltrials.gov/study/NCT06413498",
"title": "A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2024-08-23",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06474299",
"publication_url": "https://clinicaltrials.gov/study/NCT06474299",
"title": "Dual Use Cessation: A MOST Screening Trial to Identify Effective Interventions to Help People Who Smoke and Vape",
"has_exemption": false,
"start_date": "2024-09-24",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06444880",
"publication_url": "https://clinicaltrials.gov/study/NCT06444880",
"title": "Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies",
"has_exemption": false,
"start_date": "2024-10-09",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06268015",
"publication_url": "https://clinicaltrials.gov/study/NCT06268015",
"title": "Botensilimab and Balstilimab Optimization in Colorectal Cancer (BBOpCo)",
"has_exemption": false,
"start_date": "2024-11-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nicholas DeVito, MD",
"sponsor_slug": "nicholas-devito-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06246396",
"publication_url": "https://clinicaltrials.gov/study/NCT06246396",
"title": "Antihypertensive Mechanisms of Minocycline in Resistant Hypertension: Role of the Gut Microbiota-brain-immune Axis",
"has_exemption": false,
"start_date": "2025-01-08",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07042815",
"publication_url": "https://clinicaltrials.gov/study/NCT07042815",
"title": "Multi Site Long-term Follow-up for Those With Experimental Epidural Stimulation After Severe Spinal Cord Injury",
"has_exemption": false,
"start_date": "2025-01-13",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kessler Foundation",
"sponsor_slug": "kessler-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06709703",
"publication_url": "https://clinicaltrials.gov/study/NCT06709703",
"title": "L'Alignement cinématique Dans Les prothèses de Totales de Genou : un Essai randomisé contrôlé à Double Insu Comparant la Robotique Aux Instruments Traditionnels",
"has_exemption": false,
"start_date": "2025-02-28",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Université de Sherbrooke",
"sponsor_slug": "universite-de-sherbrooke",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07304024",
"publication_url": "https://clinicaltrials.gov/study/NCT07304024",
"title": "A Double-Blinded, Placebo-Controlled, Randomized, Phase 1/2a Clinical Study to Test the Safety and Efficacy of a Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound",
"has_exemption": false,
"start_date": "2025-03-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06802224",
"publication_url": "https://clinicaltrials.gov/study/NCT06802224",
"title": "Norepinephrine vs Phenylephrine as the First-line Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-cardiac Surgery",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06822790",
"publication_url": "https://clinicaltrials.gov/study/NCT06822790",
"title": "A Phase 3 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia (SHASTA-10 Study)",
"has_exemption": false,
"start_date": "2025-04-09",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arrowhead Pharmaceuticals",
"sponsor_slug": "arrowhead-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06527222",
"publication_url": "https://clinicaltrials.gov/study/NCT06527222",
"title": "Ranolazine in ALS: Safety, and Effect on Cramps, Function and Quality of Life.",
"has_exemption": false,
"start_date": "2025-04-29",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Swathy Chandrashekhar, MBBS",
"sponsor_slug": "swathy-chandrashekhar-mbbs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899178",
"publication_url": "https://clinicaltrials.gov/study/NCT06899178",
"title": "A Phase 2, Double Blind, Randomized, Placebo-controlled Crossover Trial to Evaluate the Efficacy and Safety of Atomoxetine in Adults With Melanocortin Obesity Syndrome",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06701669",
"publication_url": "https://clinicaltrials.gov/study/NCT06701669",
"title": "Phase 2 Clinical Platform Trial Investigating Multiple Therapeutic Options for the Treatment of Hospitalized Patients With Acute Respiratory Distress Syndrome (ARDS)",
"has_exemption": false,
"start_date": "2025-06-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PPD DEVELOPMENT, LP",
"sponsor_slug": "ppd-development-lp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06703073",
"publication_url": "https://clinicaltrials.gov/study/NCT06703073",
"title": "Phase 2 Clinical Platform Trial Investigating Multiple Therapeutic Options for the Treatment of Hospitalized Patients With Acute Respiratory Distress Syndrome (ARDS)",
"has_exemption": false,
"start_date": "2025-06-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PPD DEVELOPMENT, LP",
"sponsor_slug": "ppd-development-lp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06701682",
"publication_url": "https://clinicaltrials.gov/study/NCT06701682",
"title": "Phase 2 Clinical Platform Trial Investigating Multiple Therapeutic Options for the Treatment of Hospitalized Patients With Acute Respiratory Distress Syndrome (ARDS)",
"has_exemption": false,
"start_date": "2025-06-21",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PPD DEVELOPMENT, LP",
"sponsor_slug": "ppd-development-lp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06665997",
"publication_url": "https://clinicaltrials.gov/study/NCT06665997",
"title": "Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2025-06-26",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06979531",
"publication_url": "https://clinicaltrials.gov/study/NCT06979531",
"title": "A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunovant Sciences GmbH",
"sponsor_slug": "immunovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06714864",
"publication_url": "https://clinicaltrials.gov/study/NCT06714864",
"title": "An Open-Label, Two-Arm (DefenCath® vs. Institutional Standard of Care) Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to Less Than 18 Years of Age With Kidney Failure Receiving Hemodialysis Via a Central Venous Catheter",
"has_exemption": false,
"start_date": "2025-07-08",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CorMedix",
"sponsor_slug": "cormedix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06838676",
"publication_url": "https://clinicaltrials.gov/study/NCT06838676",
"title": "A Phase II Trial of ACT001 in Children and Adolescents With Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas",
"has_exemption": false,
"start_date": "2025-07-10",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07023003",
"publication_url": "https://clinicaltrials.gov/study/NCT07023003",
"title": "Postpartum Evaluation of Antihypertensives for Control of Hypertension: A Randomized Controlled Equivalence Study",
"has_exemption": false,
"start_date": "2025-07-11",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nebraska Methodist Health System",
"sponsor_slug": "nebraska-methodist-health-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07021014",
"publication_url": "https://clinicaltrials.gov/study/NCT07021014",
"title": "Improving Cardiovascular Health in Women With PTSD by Treating Trauma-Related Nightmares With NightWare",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06918119",
"publication_url": "https://clinicaltrials.gov/study/NCT06918119",
"title": "Characterization of Transcutaneous Spinal Cord Stimulation for Enabling Reflex Motor Evoked Responses in Children and Youth With Spina Bifida",
"has_exemption": false,
"start_date": "2025-08-07",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961344",
"publication_url": "https://clinicaltrials.gov/study/NCT06961344",
"title": "An Open-label Extension Study Evaluating the Safety of Zagociguat in Participants With MELAS Who Completed TIS6463-203",
"has_exemption": false,
"start_date": "2025-08-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tisento Therapeutics",
"sponsor_slug": "tisento-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07196501",
"publication_url": "https://clinicaltrials.gov/study/NCT07196501",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Maintenance of Effect of NBI-1065845 as an Adjunctive Treatment in Subjects With Major Depressive Disorder (MDD)",
"has_exemption": false,
"start_date": "2025-08-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07160725",
"publication_url": "https://clinicaltrials.gov/study/NCT07160725",
"title": "A Phase 1/2a, First-in-human, Open-label Study of BMS-986517 as Monotherapy in Adult Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06701656",
"publication_url": "https://clinicaltrials.gov/study/NCT06701656",
"title": "Phase 2 Clinical Platform Trial Investigating Multiple Therapeutic Options for the Treatment of Hospitalized Patients With Acute Respiratory Distress Syndrome (ARDS)",
"has_exemption": false,
"start_date": "2025-10-28",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PPD DEVELOPMENT, LP",
"sponsor_slug": "ppd-development-lp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07187115",
"publication_url": "https://clinicaltrials.gov/study/NCT07187115",
"title": "A Global Randomized Trial Comparing Pulsed Field Ablation of Pulmonary Veins Plus Extra-PV Sources Utilizing Electrographic Flow Mapping Versus Pulmonary Veins Plus Posterior Wall in Persistent Atrial Fibrillation Patients.",
"has_exemption": false,
"start_date": "2025-11-07",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Scientific Corporation",
"sponsor_slug": "boston-scientific-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07112053",
"publication_url": "https://clinicaltrials.gov/study/NCT07112053",
"title": "A Phase II Study of STEMVAC Vaccine Therapy for Patients With Hormone Receptor Positive Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2025-11-17",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215598",
"publication_url": "https://clinicaltrials.gov/study/NCT07215598",
"title": "Accuracy of Invisalign Attachments: A Split-Mouth Comparative Study of Optimized and Conventional Designs",
"has_exemption": false,
"start_date": "2025-11-20",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07085039",
"publication_url": "https://clinicaltrials.gov/study/NCT07085039",
"title": "A Phase II, Single-Arm Open-Label Multi-Center Study of Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease",
"has_exemption": false,
"start_date": "2025-12-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07155200",
"publication_url": "https://clinicaltrials.gov/study/NCT07155200",
"title": "Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)",
"has_exemption": false,
"start_date": "2025-12-18",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06956404",
"publication_url": "https://clinicaltrials.gov/study/NCT06956404",
"title": "Transcranial Photobiomodulation in Older Adults With Traumatic Brain Injury: Effects on Cerebral Blood Flow and Cognition",
"has_exemption": false,
"start_date": "2025-12-29",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07033598",
"publication_url": "https://clinicaltrials.gov/study/NCT07033598",
"title": "A Randomized Phase 2 Study of Pacritinib vs. Hydroxyurea in Patients With Advanced Proliferative Chronic Myelomonocytic Leukemia",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Theradex",
"sponsor_slug": "theradex",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06444412",
"publication_url": "https://clinicaltrials.gov/study/NCT06444412",
"title": "GA-68 PSMA-11 PET To Evaluate Malignant Glioma Recurrence - A Pilot Study",
"has_exemption": false,
"start_date": "2026-01-12",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222332",
"publication_url": "https://clinicaltrials.gov/study/NCT07222332",
"title": "A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Preserve Beta Cell Function in Participants Newly Diagnosed With Type 1 Diabetes Aged ≥1 to <36 Years",
"has_exemption": false,
"start_date": "2026-02-05",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07465614",
"publication_url": "https://clinicaltrials.gov/study/NCT07465614",
"title": "Auricular Neurostimulation for Children With Cyclic Vomiting Syndrome: A Randomized, Sham Controlled Trial",
"has_exemption": false,
"start_date": "2026-02-11",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07166133",
"publication_url": "https://clinicaltrials.gov/study/NCT07166133",
"title": "GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study",
"has_exemption": false,
"start_date": "2026-03-02",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07387471",
"publication_url": "https://clinicaltrials.gov/study/NCT07387471",
"title": "A Phase 2 Study of Venetoclax Monotherapy in Japanese Subjects With Relapsed or Refractory Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma",
"has_exemption": false,
"start_date": "2026-03-17",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224100",
"publication_url": "https://clinicaltrials.gov/study/NCT07224100",
"title": "Phase II Study of Dose-Adjusted EPOCH ± Rituximab + Ponatinib for Adults With Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma",
"has_exemption": false,
"start_date": "2026-03-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07496567",
"publication_url": "https://clinicaltrials.gov/study/NCT07496567",
"title": "A Randomized Double-masked, Multicenter, 3-arm, Pivotal Phase 2/3 Study to Evaluate the Efficacy and Safety of Intravitreal (IVT) EYE201/MK-8748 Compared to Aflibercept (2 mg) in Participants With Neovascular Age-related Macular Degeneration (NVAMD)",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "EyeBiotech Ltd.",
"sponsor_slug": "eyebiotech-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06902714",
"publication_url": "https://clinicaltrials.gov/study/NCT06902714",
"title": "Evaluating the Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty: A Randomized Control Trial",
"has_exemption": false,
"start_date": "2026-04-20",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07419464",
"publication_url": "https://clinicaltrials.gov/study/NCT07419464",
"title": "The 5-Fluorouracil Response and Optimization STudy (The FROST Trial): A Randomized Phase II Trial of Two Dosage Regimens (2D-Q2W vs 4D-Q3W) of 5-Fluorouracil (5-FU) in Patients With Platinum and PD-1 Inhibitor Pre-treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2026-04-21",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06552637",
"publication_url": "https://clinicaltrials.gov/study/NCT06552637",
"title": "RECOVER-HF - RandomizEd, Multi-Center, Double-Blinded Study of SynchrOnized Diaphragmatic Stimulation (SDS) for ImproVEment of Symptomatic Reduced Ejection Fraction Heart Failure",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VisCardia Inc.",
"sponsor_slug": "viscardia-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07486934",
"publication_url": "https://clinicaltrials.gov/study/NCT07486934",
"title": "A Phase 3, Randomized, Double-Blind, 48-Week Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of DYNE-101 Administered to Participants With Myotonic Dystrophy Type 1",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dyne Therapeutics",
"sponsor_slug": "dyne-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06790602",
"publication_url": "https://clinicaltrials.gov/study/NCT06790602",
"title": "A Single-arm, Open-label, Phase II Trial of Cemiplimab Plus Gemcitabine as Second-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma Harboring SWItch/Sucrose Non-Fermentable (SWI/SNF) Alterations.",
"has_exemption": false,
"start_date": "2026-05-06",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07339176",
"publication_url": "https://clinicaltrials.gov/study/NCT07339176",
"title": "A Phase 1/2 Open-Label, Dose Finding and Expansion Study to Investigate the Safety and Effectiveness and Determination of the Optimal Dose of N17350 Administered Intratumorally in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Onchilles Pharma Inc",
"sponsor_slug": "onchilles-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07635576",
"publication_url": "https://clinicaltrials.gov/study/NCT07635576",
"title": "Defining the Effect of Gastric Electrical Stimulation on Serum Insulin Levels in Human Subjects",
"has_exemption": false,
"start_date": "2026-06-08",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225998",
"publication_url": "https://clinicaltrials.gov/study/NCT07225998",
"title": "The NAGIC Study: Multi-center, Randomized, Double-blind, Placebo-controlled Cross-over Study of Oral N-acetylglucosamine in Ileal/Ileocolonic Crohn's Disease",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07424677",
"publication_url": "https://clinicaltrials.gov/study/NCT07424677",
"title": "A Double-blind, Placebo-controlled, Randomized, Phase 3 Study to Evaluate the Efficacy and Safety of Saroglitazar Magnesium on Normalization of Alkaline Phosphatase Levels in Patients With Primary Biliary Cholangitis and an Incomplete Response or Intolerance to Ursodeoxycholic Acid",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zydus Therapeutics Inc.",
"sponsor_slug": "zydus-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07609472",
"publication_url": "https://clinicaltrials.gov/study/NCT07609472",
"title": "Prospective, Single Group, Open-label Multicenter Phase 2 Study With Single-dose Administration of the Optical Imaging Agent FG001 in Subjects With Newly Diagnosed High Grade Glioma Scheduled for Neurosurgical Tumor Resection Under NIR Fluorescence Guidance",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "FluoGuide A/S",
"sponsor_slug": "fluoguide-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07606365",
"publication_url": "https://clinicaltrials.gov/study/NCT07606365",
"title": "A Phase 2, Multicentre, Randomised, Double-masked, Placebo-controlled, Parallel-group, Dose-range Finding Study, to Assess the Efficacy and Safety of Oral STL303 in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sitala Bio LTD",
"sponsor_slug": "sitala-bio-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07583862",
"publication_url": "https://clinicaltrials.gov/study/NCT07583862",
"title": "The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Geisinger Clinic",
"sponsor_slug": "geisinger-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07588698",
"publication_url": "https://clinicaltrials.gov/study/NCT07588698",
"title": "Epcoritamab in Combination With R-CHOP Debulking in Newly Diagnosed Patients With Aggressive Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mwanasha Merrill, MD",
"sponsor_slug": "mwanasha-merrill-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07637370",
"publication_url": "https://clinicaltrials.gov/study/NCT07637370",
"title": "FROST-STERN: Functional Recovery and Opioid Sparing Technique for STERNotomy A Randomized Trial of Intraoperative Intercostal Cryoablation for Postoperative Pain Management Following Full Sternotomy",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rutgers, The State University of New Jersey",
"sponsor_slug": "rutgers-the-state-university-of-new-jersey",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06906029",
"publication_url": "https://clinicaltrials.gov/study/NCT06906029",
"title": "Abdominal aBscess Catheter Sclerotherapy (ABCS)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07131722",
"publication_url": "https://clinicaltrials.gov/study/NCT07131722",
"title": "An Open-Label, Dose-Finding, Phase 1/2a Study to Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PRG Science & Technology Co., Ltd.",
"sponsor_slug": "prg-science-technology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07249554",
"publication_url": "https://clinicaltrials.gov/study/NCT07249554",
"title": "Preliminary Safety and Efficacy of Semaglutide and Naltrexone Combination Therapy for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07413172",
"publication_url": "https://clinicaltrials.gov/study/NCT07413172",
"title": "The Effect of Autologous Serum Tears Diluted to 50% With 0.2% Sodium Hyaluronate-Containing Preservative-Free Artificial Tears Versus Autologous Serum Tears Diluted to 50% With Balanced Salt Solution in Patients With Moderate-to-Severe Dry Eye Disease: A Prospective, Double-Blind, Randomized, Controlled, Contralateral-Eye Study",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07573163",
"publication_url": "https://clinicaltrials.gov/study/NCT07573163",
"title": "A Randomized Clinical Trial of Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alaa Sada",
"sponsor_slug": "alaa-sada",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07581405",
"publication_url": "https://clinicaltrials.gov/study/NCT07581405",
"title": "GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric Cancer",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07596212",
"publication_url": "https://clinicaltrials.gov/study/NCT07596212",
"title": "BRE-06: Study to Increase Tolerance to Aromatase Inhibitors for Patients With Early-Stage Hormone Receptor Positive Breast Cancer Who Developed Hypoactive Sexual Desire Disorder",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07605949",
"publication_url": "https://clinicaltrials.gov/study/NCT07605949",
"title": "Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07631325",
"publication_url": "https://clinicaltrials.gov/study/NCT07631325",
"title": "A Phase Ib/II Evaluation of the Effects of Axelopran in Patients With Anti-PD-1 Refractory Metastatic or Locoregionally Unresectable Cutaneous Melanoma",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "John Kirkwood",
"sponsor_slug": "john-kirkwood",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07526285",
"publication_url": "https://clinicaltrials.gov/study/NCT07526285",
"title": "Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06987383",
"publication_url": "https://clinicaltrials.gov/study/NCT06987383",
"title": "Vibegron - A Novel Treatment for Multisystem Functional Decline in Aging and Obesity",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07473843",
"publication_url": "https://clinicaltrials.gov/study/NCT07473843",
"title": "Phase 3 Single-Arm Open-Label Study to Evaluate the Efficacy and Safety of Zodasiran in Adolescent Participants (Age 12 to <18 Years) With Homozygous Familial Hypercholesterolemia (SPRUCE)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arrowhead Pharmaceuticals",
"sponsor_slug": "arrowhead-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07579351",
"publication_url": "https://clinicaltrials.gov/study/NCT07579351",
"title": "Corticosteroid Lumbar Epidural Analgesia for Radicular Pain (C.L.E.A.R) 2 - A Randomized, Double-blind, Active Comparator and Placebo-controlled, Multicenter, Safety and Efficacy Trial of SP-102",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Semnur Pharmaceuticals, Inc.",
"sponsor_slug": "semnur-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07638722",
"publication_url": "https://clinicaltrials.gov/study/NCT07638722",
"title": "MOZART MZL: A Randomized Phase II Study Evaluating Mosunetuzumab Alone and in Combination With Either Zanubrutinib or Polatuzumab Vedotin for the Treatment of Patients With Relapsed/Refractory Marginal Zone Lymphoma",
"has_exemption": false,
"start_date": "2026-10-03",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04860635",
"publication_url": "https://clinicaltrials.gov/study/NCT04860635",
"title": "An Open Label Safety Study of a Single Administration of F14 in Patients Undergoing Unilateral Total Knee Replacement",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arthritis Innovation Corporation",
"sponsor_slug": "arthritis-innovation-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214194",
"publication_url": "https://clinicaltrials.gov/study/NCT07214194",
"title": "Vagus Nerve Stimulation to Enhance Memory in Aging",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2028-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03281798",
"publication_url": "https://clinicaltrials.gov/study/NCT03281798",
"title": "Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (LUTO): A Prospective Trial",
"has_exemption": false,
"start_date": "2018-01-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rodrigo Ruano",
"sponsor_slug": "rodrigo-ruano",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03675893",
"publication_url": "https://clinicaltrials.gov/study/NCT03675893",
"title": "RESOLVE: letRozole abEmaciclib combinationS in endOmetriaL and oVarian cancEr: A Multi-Cohort Phase 2 Study of Letrozole/Abemaciclib Alone and in Combination With Metformin, Zotatifin and Gedatolisib",
"has_exemption": false,
"start_date": "2018-12-24",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03746769",
"publication_url": "https://clinicaltrials.gov/study/NCT03746769",
"title": "Improving Islet Transplantation Outcomes With Gastrin",
"has_exemption": false,
"start_date": "2019-07-07",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04164173",
"publication_url": "https://clinicaltrials.gov/study/NCT04164173",
"title": "Hyperinflation Respiratory Therapies in Cardiac Surgery Patients: A Randomized, Observer-Blinded, Prospective Clinical Trial",
"has_exemption": false,
"start_date": "2020-06-15",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05541016",
"publication_url": "https://clinicaltrials.gov/study/NCT05541016",
"title": "DART 2.0: ctHPV-DNA Informed De-Escalated Adjuvant and Definitive Radiation Therapy",
"has_exemption": false,
"start_date": "2023-02-21",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05800587",
"publication_url": "https://clinicaltrials.gov/study/NCT05800587",
"title": "Phase II Study of Dose Attenuated Chemotherapy in Patients With Lung Cancer and Age > 70 and/or Comorbidities",
"has_exemption": false,
"start_date": "2023-02-22",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Fox Chase Cancer Center",
"sponsor_slug": "fox-chase-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05588141",
"publication_url": "https://clinicaltrials.gov/study/NCT05588141",
"title": "A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations",
"has_exemption": false,
"start_date": "2023-05-16",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05770531",
"publication_url": "https://clinicaltrials.gov/study/NCT05770531",
"title": "A Randomized Clinical Trial Comparing ctDNA-Directed Therapy Change With Standard of Care in Patients With Metastatic Triple Negative Breast Cancer",
"has_exemption": false,
"start_date": "2023-08-04",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06143059",
"publication_url": "https://clinicaltrials.gov/study/NCT06143059",
"title": "Sex and Sex Hormone Factors Influencing Acute Alcohol Effects on Sleep Physiology",
"has_exemption": false,
"start_date": "2024-01-08",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Lauren Whitehurst",
"sponsor_slug": "lauren-whitehurst",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04915183",
"publication_url": "https://clinicaltrials.gov/study/NCT04915183",
"title": "Phase II Interventional Study Using Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer",
"has_exemption": false,
"start_date": "2024-07-10",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute on Deafness and Other Communication Disorders (NIDCD)",
"sponsor_slug": "national-institute-on-deafness-and-other-communication-disorders-nidcd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06529406",
"publication_url": "https://clinicaltrials.gov/study/NCT06529406",
"title": "Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod (COAST: CD20 and Ozanimod Sequencing Trial)",
"has_exemption": false,
"start_date": "2024-07-29",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06989099",
"publication_url": "https://clinicaltrials.gov/study/NCT06989099",
"title": "Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial",
"has_exemption": false,
"start_date": "2024-09-24",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06517641",
"publication_url": "https://clinicaltrials.gov/study/NCT06517641",
"title": "A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Haploidentical Related, Partially HLA-Mismatched, or Matched Unrelated Bone Marrow for Newly Diagnosed Patients With Severe Aplastic Anemia",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06839053",
"publication_url": "https://clinicaltrials.gov/study/NCT06839053",
"title": "SONIC: Escalated Inpatient Ramp-Up of Sonrotoclax in Patients With Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), and Mantle Cell Lymphoma (MCL) (SONIC Study)",
"has_exemption": false,
"start_date": "2025-06-02",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076095",
"publication_url": "https://clinicaltrials.gov/study/NCT07076095",
"title": "A Phase II/III Study to Compare IBB0979 in Combination With Topotecan Versus Topotecan in Subjects With Relapsed Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "SUNHO（China）BioPharmaceutical CO., Ltd.",
"sponsor_slug": "sunhochinabiopharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07062003",
"publication_url": "https://clinicaltrials.gov/study/NCT07062003",
"title": "A Dose Finding Study of MiniBeam RadioTherapy for Skin and Superficial Soft Tissue Tumors (MBRT1)",
"has_exemption": false,
"start_date": "2025-08-11",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07503444",
"publication_url": "https://clinicaltrials.gov/study/NCT07503444",
"title": "A Phase 3 Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multicenter Study With Open-Label Extension to Evaluate the Efficacy And Safety of Fenfluramine Hydrochloride in Study Participants With Rett Syndrome",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB BIOSCIENCES, Inc.",
"sponsor_slug": "ucb-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07441200",
"publication_url": "https://clinicaltrials.gov/study/NCT07441200",
"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Finding Trial to Evaluate the Efficacy and Safety of Orally Administered NS-863 in Participants With Pulmonary Arterial Hypertension (PAH)",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "NS Pharma, Inc.",
"sponsor_slug": "ns-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07502339",
"publication_url": "https://clinicaltrials.gov/study/NCT07502339",
"title": "An Open-Label, Investigator-Initiated Study Evaluating the Use of Upadacitinib in Patients Hospitalized With Acute Severe Ulcerative Colitis",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07635524",
"publication_url": "https://clinicaltrials.gov/study/NCT07635524",
"title": "A Two Center Phase 2 Trial of 61Cu-noDAGa-PSMA I&T (61Cu-NU101) for Patients With Prostate Cancer",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoag Memorial Hospital Presbyterian",
"sponsor_slug": "hoag-memorial-hospital-presbyterian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07644923",
"publication_url": "https://clinicaltrials.gov/study/NCT07644923",
"title": "A Randomized, Single-Blinded, Controlled Study Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07018297",
"publication_url": "https://clinicaltrials.gov/study/NCT07018297",
"title": "Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure: A Cluster-Randomized Crossover Non-Inferiority Trial",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06127550",
"publication_url": "https://clinicaltrials.gov/study/NCT06127550",
"title": "Effect of Non-invasive Vagus Nerve Stimulation on Letter Learning in Dyslexia",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07612007",
"publication_url": "https://clinicaltrials.gov/study/NCT07612007",
"title": "Phase 2B Study to Determine Efficacy of HRX215, a First Generation MKK4 Inhibitor Drug, in Improving Regeneration of the Remnant Liver After Portal Vein Embolization (PVE) of Colorectal Liver Metastasis (CRLM)",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07622472",
"publication_url": "https://clinicaltrials.gov/study/NCT07622472",
"title": "Remote Monitoring and Optimization of Heart Failure Therapy",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2028-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Zoll Medical Corporation",
"sponsor_slug": "zoll-medical-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05070845",
"publication_url": "https://clinicaltrials.gov/study/NCT05070845",
"title": "AN INTERVENTIONAL PHASE 2, OPEN-LABEL, MULTI-CENTER STUDY TO EVALUATE SAFETY AND EFFICACY OF PF-06835375 IN ADULT PARTICIPANTS WITH MODERATE TO SEVERE PRIMARY IMMUNE THROMBOCYTOPENIA",
"has_exemption": false,
"start_date": "2022-02-02",
"completion_date": "2028-08-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06136624",
"publication_url": "https://clinicaltrials.gov/study/NCT06136624",
"title": "A Phase 3 Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) Previously Treated With Next-generation Hormonal Agent (NHA) and Taxane-based Chemotherapy (OMAHA-003)",
"has_exemption": false,
"start_date": "2023-12-31",
"completion_date": "2028-08-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06997588",
"publication_url": "https://clinicaltrials.gov/study/NCT06997588",
"title": "Study Assessing the Efficacy, Safety and Pharmacokinetics of Alpelisib in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)",
"has_exemption": false,
"start_date": "2025-10-09",
"completion_date": "2028-08-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07499102",
"publication_url": "https://clinicaltrials.gov/study/NCT07499102",
"title": "CK0801 for Treatment of Aplastic Anemia",
"has_exemption": false,
"start_date": "2026-08-03",
"completion_date": "2028-08-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Cellenkos, Inc.",
"sponsor_slug": "cellenkos-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07515014",
"publication_url": "https://clinicaltrials.gov/study/NCT07515014",
"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose Response Study to Evaluate the Efficacy and Safety of E6742 in Subjects With Systemic Lupus Erythematosus",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2028-08-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Eisai Co., Ltd.",
"sponsor_slug": "eisai-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07087860",
"publication_url": "https://clinicaltrials.gov/study/NCT07087860",
"title": "MC220503 Randomized Phase II Rescuing Cancer Immunotherapy With Plasma Exchange in Bladder Cancer 1 (ReCIPE-B1)",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2028-08-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07124520",
"publication_url": "https://clinicaltrials.gov/study/NCT07124520",
"title": "Normative Ranges of Lingual Strength and Endurance and the Impact of the IOPI Lingual Strength Trainer on Quantitative Functional Outcomes and Patient-Reported Outcomes After Partial Glossectomy or Hemiglossectomy for Oral Tongue Cancer, A Pilot Study",
"has_exemption": false,
"start_date": "2025-08-07",
"completion_date": "2028-08-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07351058",
"publication_url": "https://clinicaltrials.gov/study/NCT07351058",
"title": "A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 Administered to Participants With Obesity or Overweight and Type 2 Diabetes",
"has_exemption": false,
"start_date": "2026-03-23",
"completion_date": "2028-08-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07533175",
"publication_url": "https://clinicaltrials.gov/study/NCT07533175",
"title": "Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Type 2 Diabetes (AMAZE 2)",
"has_exemption": false,
"start_date": "2026-04-13",
"completion_date": "2028-08-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07011810",
"publication_url": "https://clinicaltrials.gov/study/NCT07011810",
"title": "Axatilimab for Sclerotic Chronic Graft-Versus-Host Disease",
"has_exemption": false,
"start_date": "2025-08-06",
"completion_date": "2028-08-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221019",
"publication_url": "https://clinicaltrials.gov/study/NCT07221019",
"title": "Single-Shot Exparel Versus Catheters for Lower Extremity Orthopedic Trauma Patients",
"has_exemption": false,
"start_date": "2025-09-12",
"completion_date": "2028-08-11",
"has_results": false,
"results_due": false,
"sponsor_name": "George Washington University",
"sponsor_slug": "george-washington-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07577856",
"publication_url": "https://clinicaltrials.gov/study/NCT07577856",
"title": "A Phase 3 Randomized, Double-blind, and Active Controlled, Multi-center Study to Evaluate the Efficacy and Safety of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis",
"has_exemption": false,
"start_date": "2026-05-23",
"completion_date": "2028-08-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05540327",
"publication_url": "https://clinicaltrials.gov/study/NCT05540327",
"title": "A Phase II, Double-blind, Dose-Ranging, Parallel, Long-term Extension Study to Evaluate the Safety and Efficacy of Enpatoran in Participants With Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus and/or Systemic Lupus Erythematosus Having Completed the WILLOW (MS200569_0003) Study Treatment (WILLOW LTE)",
"has_exemption": false,
"start_date": "2022-09-16",
"completion_date": "2028-08-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany",
"sponsor_slug": "merck-healthcare-kgaa-darmstadt-germany-an-affiliate-of-merck-kgaa-darmstadt-germany",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05989763",
"publication_url": "https://clinicaltrials.gov/study/NCT05989763",
"title": "Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis",
"has_exemption": false,
"start_date": "2024-02-17",
"completion_date": "2028-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06356129",
"publication_url": "https://clinicaltrials.gov/study/NCT06356129",
"title": "A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Golcadomide Plus R-CHOP Chemotherapy vs Placebo Plus R-CHOP Chemotherapy in Participants With Previously Untreated High-risk Large B-cell Lymphoma (GOLSEEK-1)",
"has_exemption": false,
"start_date": "2024-06-19",
"completion_date": "2028-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Celgene",
"sponsor_slug": "celgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07405359",
"publication_url": "https://clinicaltrials.gov/study/NCT07405359",
"title": "A Randomized Trial of Pulmonary Vein Isolation Alone Versus Pulmonary Vein Isolation Plus Posterior Wall and Superior Vena Cava Isolation With Pulsed Field Ablation for Treatment of Persistent Atrial Fibrillation",
"has_exemption": false,
"start_date": "2026-02-14",
"completion_date": "2028-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Edward Gerstenfeld, MD",
"sponsor_slug": "edward-gerstenfeld-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07481630",
"publication_url": "https://clinicaltrials.gov/study/NCT07481630",
"title": "Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Knee Osteoarthritis (AMAZE 5)",
"has_exemption": false,
"start_date": "2026-04-13",
"completion_date": "2028-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07509307",
"publication_url": "https://clinicaltrials.gov/study/NCT07509307",
"title": "Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Knee Osteoarthritis (AMAZE 6)",
"has_exemption": false,
"start_date": "2026-04-20",
"completion_date": "2028-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05467891",
"publication_url": "https://clinicaltrials.gov/study/NCT05467891",
"title": "A Phase II Study of Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer",
"has_exemption": false,
"start_date": "2022-09-13",
"completion_date": "2028-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Oana Danciu",
"sponsor_slug": "oana-danciu",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06581003",
"publication_url": "https://clinicaltrials.gov/study/NCT06581003",
"title": "Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2028-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of South Florida",
"sponsor_slug": "university-of-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07030257",
"publication_url": "https://clinicaltrials.gov/study/NCT07030257",
"title": "A Multi-Center, Open Label, Phase 1/2 Study of CP-383, in Patients With Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-27",
"completion_date": "2028-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Tasca Therapeutics",
"sponsor_slug": "tasca-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07565103",
"publication_url": "https://clinicaltrials.gov/study/NCT07565103",
"title": "A Phase I/II Trial to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of SUM-191 in Healthy Participants and in Participants With Bacterial Conjunctivitis",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2028-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Senju USA, Inc.",
"sponsor_slug": "senju-usa-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06007937",
"publication_url": "https://clinicaltrials.gov/study/NCT06007937",
"title": "A Phase 1/2 Study of Combination Lorlatinib and Ramucirumab in Patients With Advanced ALK-rearranged Lung Cancers",
"has_exemption": false,
"start_date": "2023-08-17",
"completion_date": "2028-08-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06305754",
"publication_url": "https://clinicaltrials.gov/study/NCT06305754",
"title": "A Randomized, Open-label, Phase 3 Study of MK-2870 vs. Platinum Doublets in Participants With EGFR-mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2028-08-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05866562",
"publication_url": "https://clinicaltrials.gov/study/NCT05866562",
"title": "Dupilumab in the Treatment of Pediatric Alopecia Areata",
"has_exemption": false,
"start_date": "2024-07-11",
"completion_date": "2028-08-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843967",
"publication_url": "https://clinicaltrials.gov/study/NCT06843967",
"title": "A Phase Ib/II Study of the Mirdametinib in Combination With Palbociclib in Patients With Advanced Dedifferentiated Liposarcoma",
"has_exemption": false,
"start_date": "2025-02-19",
"completion_date": "2028-08-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06292780",
"publication_url": "https://clinicaltrials.gov/study/NCT06292780",
"title": "A Phase 1/2 Study of Linvoseltamab in Patients With Relapsed or Refractory Systemic Light Chain Amyloidosis",
"has_exemption": false,
"start_date": "2024-08-07",
"completion_date": "2028-08-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06425549",
"publication_url": "https://clinicaltrials.gov/study/NCT06425549",
"title": "A Multicenter, Randomized, Parallel-Group, Double-Blind, Active-Controlled Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis",
"has_exemption": false,
"start_date": "2024-06-25",
"completion_date": "2028-08-21",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06463587",
"publication_url": "https://clinicaltrials.gov/study/NCT06463587",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm, 3-Period Study to Assess the Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)",
"has_exemption": false,
"start_date": "2024-06-25",
"completion_date": "2028-08-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany",
"sponsor_slug": "merck-healthcare-kgaa-darmstadt-germany-an-affiliate-of-merck-kgaa-darmstadt-germany",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06597565",
"publication_url": "https://clinicaltrials.gov/study/NCT06597565",
"title": "A Phase II Study of ACR-368 and Low Dose Gemcitabine Combination Therapy in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2024-09-25",
"completion_date": "2028-08-23",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07573176",
"publication_url": "https://clinicaltrials.gov/study/NCT07573176",
"title": "A Multicenter, Double-blind, Randomized, Placebo-controlled Study to Evaluate Efficacy and Safety of Seltorexant as Monotherapy in Adult and Elderly Participants With Major Depressive Disorder (MDD) and an Open-label Long-term Extension Treatment With Seltorexant",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2028-08-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07173153",
"publication_url": "https://clinicaltrials.gov/study/NCT07173153",
"title": "Phase I/II Intrathecal Gene Delivery Clinical Trial of scAAV9.P546.SLC6A1 for SLC6A1 Neurodevelopmental Disorder",
"has_exemption": false,
"start_date": "2025-08-25",
"completion_date": "2028-08-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Emily de los Reyes",
"sponsor_slug": "emily-de-los-reyes",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06165341",
"publication_url": "https://clinicaltrials.gov/study/NCT06165341",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis",
"has_exemption": false,
"start_date": "2024-03-01",
"completion_date": "2028-08-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06780449",
"publication_url": "https://clinicaltrials.gov/study/NCT06780449",
"title": "Long-term Efficacy and Safety of Cagrilintide s.c. 2.4 mg in Combination With Semaglutide s.c. 2.4 mg (CagriSema 2.4 mg/2.4 mg) Once Weekly Versus Placebo in Participants With Obesity",
"has_exemption": false,
"start_date": "2025-02-10",
"completion_date": "2028-08-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05156983",
"publication_url": "https://clinicaltrials.gov/study/NCT05156983",
"title": "A Phase 3, Prospective, Randomized, Open-label, Adaptive Group Sequential, Multicenter Trial With Blinded Endpoint Assessment to Evaluate the Efficacy and Safety of TAK-330 for the Reversal of Direct Oral Factor Xa Inhibitor-induced Anticoagulation in Patients Requiring Urgent Surgery/Invasive Procedure",
"has_exemption": false,
"start_date": "2022-08-24",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06531824",
"publication_url": "https://clinicaltrials.gov/study/NCT06531824",
"title": "A Multicenter, International, Randomized, Double-blind, Placebo-controlled Clinical Trial of the Aldosterone Synthase Inhibitor BI 690517 in Combination With Empagliflozin in Patients With Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2024-08-30",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06858397",
"publication_url": "https://clinicaltrials.gov/study/NCT06858397",
"title": "An Open Label, Dose Range, Proof-of-Concept Study to Assess the Safety and Efficacy of HM15421/GC1134A in Patients With Fabry Disease",
"has_exemption": false,
"start_date": "2025-05-14",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GC Biopharma Corp",
"sponsor_slug": "gc-biopharma-corp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06975150",
"publication_url": "https://clinicaltrials.gov/study/NCT06975150",
"title": "A Randomized, Double-blind, Placebo-controlled, Parallel Group, 12 Weeks, Phase 2b Clinical Study to Evaluate the Efficacy and Safety of HK-660S in Patients With Primary Sclerosing Cholangitis (PSC)",
"has_exemption": false,
"start_date": "2025-08-18",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "CuromeBiosciences",
"sponsor_slug": "curomebiosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07569601",
"publication_url": "https://clinicaltrials.gov/study/NCT07569601",
"title": "The Effects of Heat Therapy and Foam Rolling on Force Production in Athletes.",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Redlands",
"sponsor_slug": "university-of-redlands",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224152",
"publication_url": "https://clinicaltrials.gov/study/NCT07224152",
"title": "NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-03-27",
"completion_date": "2028-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02530073",
"publication_url": "https://clinicaltrials.gov/study/NCT02530073",
"title": "Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)",
"has_exemption": false,
"start_date": "2015-09-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Connecticut Children's Medical Center",
"sponsor_slug": "connecticut-childrens-medical-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02521311",
"publication_url": "https://clinicaltrials.gov/study/NCT02521311",
"title": "A Randomized, Double-Blind, Parallel-Group, Placebo Controlled Trial to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis",
"has_exemption": false,
"start_date": "2017-02-28",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03008408",
"publication_url": "https://clinicaltrials.gov/study/NCT03008408",
"title": "A Phase II, Randomized Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (LEE011) in Patients With Advanced or Recurrent Endometrial Carcinoma",
"has_exemption": false,
"start_date": "2017-08-18",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03516279",
"publication_url": "https://clinicaltrials.gov/study/NCT03516279",
"title": "Phase II Study of Adding the Anti-PD-1 Pembrolizumab to Tyrosine Kinase Inhibitors in Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease",
"has_exemption": false,
"start_date": "2019-06-26",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03929432",
"publication_url": "https://clinicaltrials.gov/study/NCT03929432",
"title": "Treatment Outcomes and Brain Mechanisms Associated With Non-Invasive Neuromodulation in Post-Stroke Aphasia",
"has_exemption": false,
"start_date": "2019-09-03",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arkansas",
"sponsor_slug": "university-of-arkansas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04161898",
"publication_url": "https://clinicaltrials.gov/study/NCT04161898",
"title": "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Upadacitinib in Subjects With Takayasu Arteritis (SELECT-Takayasu)",
"has_exemption": false,
"start_date": "2020-02-04",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03875378",
"publication_url": "https://clinicaltrials.gov/study/NCT03875378",
"title": "Transdermal Estrogen for the Treatment of Bone Loss in Women With Anorexia Nervosa",
"has_exemption": false,
"start_date": "2020-08-28",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pouneh K. Fazeli, MD",
"sponsor_slug": "pouneh-k-fazeli-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04817007",
"publication_url": "https://clinicaltrials.gov/study/NCT04817007",
"title": "A Phase 1b/2 Study of BMS-986158 Monotherapy and in Combination With Either Ruxolitinib or Fedratinib in Participants With DIPSS-Intermediate or High Risk Myelofibrosis",
"has_exemption": false,
"start_date": "2021-03-22",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04873362",
"publication_url": "https://clinicaltrials.gov/study/NCT04873362",
"title": "A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy",
"has_exemption": false,
"start_date": "2021-05-04",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05004116",
"publication_url": "https://clinicaltrials.gov/study/NCT05004116",
"title": "Phase 1/2 Study of TPX-0005 (Repotrectinib) in Combination With Chemotherapy in Pediatric and Young Adult Subjects With Advanced or Metastatic Solid Tumors and Primary Central Nervous System Tumors",
"has_exemption": false,
"start_date": "2021-08-09",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04747431",
"publication_url": "https://clinicaltrials.gov/study/NCT04747431",
"title": "A Phase 1b Open-Label, Multicenter, Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacodynamic Effects of a Single Dose of PBFT02 Delivered Into the ICM of Adults With FTD and Mutations in the GRN or C9ORF72 Genes",
"has_exemption": false,
"start_date": "2021-09-14",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Passage Bio, Inc.",
"sponsor_slug": "passage-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04831580",
"publication_url": "https://clinicaltrials.gov/study/NCT04831580",
"title": "A Randomized Controlled Trial of Robotic Versus Open Surgery for Early Stage Cervical Cancer (ROCC)",
"has_exemption": false,
"start_date": "2022-03-22",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GOG Foundation",
"sponsor_slug": "gog-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05456503",
"publication_url": "https://clinicaltrials.gov/study/NCT05456503",
"title": "Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Disease Using the PET Ligand [18F]-PI-2620",
"has_exemption": false,
"start_date": "2022-09-19",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05501756",
"publication_url": "https://clinicaltrials.gov/study/NCT05501756",
"title": "Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation in Non-Malignant Diseases",
"has_exemption": false,
"start_date": "2023-01-11",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05434689",
"publication_url": "https://clinicaltrials.gov/study/NCT05434689",
"title": "Phase Ib/II Trial Of Iberdomide-Combinations In Patients With Positive Minimal Residual Disease (>10-5) After Autologous Hematopoietic Cell Transplantation In The Upfront Management Of Patients With Multiple Myeloma",
"has_exemption": false,
"start_date": "2023-01-18",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05658562",
"publication_url": "https://clinicaltrials.gov/study/NCT05658562",
"title": "A Phase I/II Open-Label Study of MT-2111 in Patients With Relapsed/Refractory DLBCL",
"has_exemption": false,
"start_date": "2023-01-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tanabe Pharma Corporation",
"sponsor_slug": "tanabe-pharma-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05461222",
"publication_url": "https://clinicaltrials.gov/study/NCT05461222",
"title": "A Study of the Effectiveness of Fetal Endoscopic Tracheal Occlusion (FETO) in the Management of Severe Prenatally Diagnosed Congenital Diaphragmatic Hernia (CDH)",
"has_exemption": false,
"start_date": "2023-04-17",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yair Blumenfeld",
"sponsor_slug": "yair-blumenfeld",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05886920",
"publication_url": "https://clinicaltrials.gov/study/NCT05886920",
"title": "A Phase 1/2, Open Label, Dose-escalation, and Dose-expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Recommended Phase 2 Dose of D3S-002 Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations",
"has_exemption": false,
"start_date": "2023-07-10",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "D3 Bio (Wuxi) Co., Ltd",
"sponsor_slug": "d3-bio-wuxi-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05585554",
"publication_url": "https://clinicaltrials.gov/study/NCT05585554",
"title": "Locally Advanced Pancreatic Cancer Treated With ABLAtivE Stereotactic MRI-guided Adaptive Radiation Therapy (LAP-ABLATE)",
"has_exemption": false,
"start_date": "2023-07-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Viewray Inc.",
"sponsor_slug": "viewray-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05967689",
"publication_url": "https://clinicaltrials.gov/study/NCT05967689",
"title": "An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations.",
"has_exemption": false,
"start_date": "2023-07-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Taiho Oncology, Inc.",
"sponsor_slug": "taiho-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06000787",
"publication_url": "https://clinicaltrials.gov/study/NCT06000787",
"title": "Molecular Characterization Trial for the Harvard/UCSF ROBIN Center: Radiation Oncology at the Interface of Pediatric Cancer Biology and Data Science",
"has_exemption": false,
"start_date": "2023-09-19",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05782907",
"publication_url": "https://clinicaltrials.gov/study/NCT05782907",
"title": "A Phase 3 Multicenter Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Upadacitinib With Open-Label Induction, Randomized, Double-Blind Maintenance and Open-Label Long-Term Extension in Pediatric Subjects With Moderately to Severely Active Ulcerative Colitis and Inadequate Response, Intolerance, or Medical Contraindications to Corticosteroids, Immunosuppressants, and/or Biologic Therapy",
"has_exemption": false,
"start_date": "2023-11-06",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06181136",
"publication_url": "https://clinicaltrials.gov/study/NCT06181136",
"title": "A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A)",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05953610",
"publication_url": "https://clinicaltrials.gov/study/NCT05953610",
"title": "Endotypic Traits and Obstructive Sleep Apnea Surgery",
"has_exemption": false,
"start_date": "2024-01-07",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06036199",
"publication_url": "https://clinicaltrials.gov/study/NCT06036199",
"title": "Safety and Impact on Quality of Life of Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects",
"has_exemption": false,
"start_date": "2024-01-26",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's National Research Institute",
"sponsor_slug": "childrens-national-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05237505",
"publication_url": "https://clinicaltrials.gov/study/NCT05237505",
"title": "The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)",
"has_exemption": false,
"start_date": "2024-02-13",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05753046",
"publication_url": "https://clinicaltrials.gov/study/NCT05753046",
"title": "Perioperative Laparoscopic Transversus Abdominis Plane Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain",
"has_exemption": false,
"start_date": "2024-02-19",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Corewell Health East",
"sponsor_slug": "corewell-health-east",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06242782",
"publication_url": "https://clinicaltrials.gov/study/NCT06242782",
"title": "Vertical Ridge Augmentation Strategies: An Adaptive Randomised Controlled Clinical Trial",
"has_exemption": false,
"start_date": "2024-02-29",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University College, London",
"sponsor_slug": "university-college-london",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06290063",
"publication_url": "https://clinicaltrials.gov/study/NCT06290063",
"title": "Rocky Mountain Cannabis Research Center - Cannabidiol and Older Adult Cannabis Users: A Randomized, Placebo-Controlled Study",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Boulder",
"sponsor_slug": "university-of-colorado-boulder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06082167",
"publication_url": "https://clinicaltrials.gov/study/NCT06082167",
"title": "A Phase 2/3, Randomized, Double-Blind, Controlled Study of Zanzalintinib (XL092) in Combination With Pembrolizumab vs Pembrolizumab in First-Line Treatment of Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2024-06-07",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Exelixis",
"sponsor_slug": "exelixis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06285643",
"publication_url": "https://clinicaltrials.gov/study/NCT06285643",
"title": "A Phase 2, Randomized, Double-blind, Sham Surgery-controlled Study of the Efficacy and Safety of Intraputaminal AAV2-GDNF in the Treatment of Adults With Moderate Stage Parkinson's Disease",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AskBio Inc",
"sponsor_slug": "askbio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06239194",
"publication_url": "https://clinicaltrials.gov/study/NCT06239194",
"title": "A Phase 1/2a, Multicenter, First-in-human, Open-label Clinical Trial Evaluating MDX2001 Monotherapy in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2024-06-12",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ModeX Therapeutics, An OPKO Health Company",
"sponsor_slug": "modex-therapeutics-an-opko-health-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05826912",
"publication_url": "https://clinicaltrials.gov/study/NCT05826912",
"title": "Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06449222",
"publication_url": "https://clinicaltrials.gov/study/NCT06449222",
"title": "A Phase II, Multi-site, Randomized, Open-label Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of BNT327 at Two Dose Levels in Combination With Chemotherapeutic Agents as First- and Second-line Treatment in Triple-negative Breast Cancer",
"has_exemption": false,
"start_date": "2024-08-26",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06377852",
"publication_url": "https://clinicaltrials.gov/study/NCT06377852",
"title": "Comparing Oral Drug Dosing Strategies in Older Patients With Metastatic Breast Cancer to Maximize Tolerance and Reduce Discontinuation: The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study",
"has_exemption": false,
"start_date": "2024-10-29",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "American Society of Clinical Oncology",
"sponsor_slug": "american-society-of-clinical-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06399653",
"publication_url": "https://clinicaltrials.gov/study/NCT06399653",
"title": "Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-01-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06136546",
"publication_url": "https://clinicaltrials.gov/study/NCT06136546",
"title": "The Role of Inflammation in Cognitive Dysfunction in Acute Depression as Determined by Experimental Inhibition of Tumor Necrosis Factor-alpha Signaling in a Randomized Controlled Trial.",
"has_exemption": false,
"start_date": "2025-01-23",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06785116",
"publication_url": "https://clinicaltrials.gov/study/NCT06785116",
"title": "A Randomized, Placebo-controlled Trial of DAPAgliflozin for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies",
"has_exemption": false,
"start_date": "2025-03-02",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06742996",
"publication_url": "https://clinicaltrials.gov/study/NCT06742996",
"title": "A Phase 3 Randomized Double-Blind Multicenter Study of Sonrotoclax Plus Zanubrutinib Versus Placebo Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06672822",
"publication_url": "https://clinicaltrials.gov/study/NCT06672822",
"title": "An Open Label Evaluation of Intralesional Injection of Sodium Thiosulfate in the Treatment of Cutaneous or Tendon Calcinosis in Connective Tissue Disease",
"has_exemption": false,
"start_date": "2025-03-17",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Robyn T. Domsic, MD, MPH",
"sponsor_slug": "robyn-t-domsic-md-mph",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07032662",
"publication_url": "https://clinicaltrials.gov/study/NCT07032662",
"title": "A Phase 2b, Multi-center, Randomized, Double-blind, Placebo-controlled Study of IMVT-1402 Treatment in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunovant Sciences GmbH",
"sponsor_slug": "immunovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06265584",
"publication_url": "https://clinicaltrials.gov/study/NCT06265584",
"title": "Phase II Clinical Trial of 2 Step ATG Combined With Tacrolimus and Mini Methotrexate for Prevention of Acute GVHD Post Reduced Intensity Allogeneic Stem Cell Transplant",
"has_exemption": false,
"start_date": "2025-04-08",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06943521",
"publication_url": "https://clinicaltrials.gov/study/NCT06943521",
"title": "A Phase I/II, Dose-escalation and Dose-optimization Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of MT-4561 in Patients With Various Advanced Solid Tumors and to Evaluate Effect of MT-4561 on Pharmacokinetics of Oral Midazolam",
"has_exemption": false,
"start_date": "2025-04-18",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tanabe Pharma America, Inc.",
"sponsor_slug": "tanabe-pharma-america-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06939283",
"publication_url": "https://clinicaltrials.gov/study/NCT06939283",
"title": "A Phase 1b/2 Multisite Dose- and Regimen-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma (NHL)",
"has_exemption": false,
"start_date": "2025-05-07",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Werewolf Therapeutics, Inc.",
"sponsor_slug": "werewolf-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07001800",
"publication_url": "https://clinicaltrials.gov/study/NCT07001800",
"title": "A Phase 2b/3, Randomized, Double-Blinded, Placebo Controlled Study ChecKing the Efficacy and Safety of ATAciguat to Slow the Progression of VaLvular DYsfunction in Participants With Moderate Calcific Aortic Valve STenosis",
"has_exemption": false,
"start_date": "2025-06-27",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kardigan, Inc.",
"sponsor_slug": "kardigan-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06678841",
"publication_url": "https://clinicaltrials.gov/study/NCT06678841",
"title": "Randomized Trial of ELEVATEd Cardiac Pacing Rate for Personalized Treatment of Heart Failure With Preserved Ejection Fraction (ELEVATE-HFpEF)",
"has_exemption": false,
"start_date": "2025-07-09",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiac Rhythm and Heart Failure",
"sponsor_slug": "medtronic-cardiac-rhythm-and-heart-failure",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06933329",
"publication_url": "https://clinicaltrials.gov/study/NCT06933329",
"title": "Phase 2 Study of Zelenectide Pevedotin in Participants With Previously-Treated NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-07-18",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BicycleTx Limited",
"sponsor_slug": "bicycletx-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06998407",
"publication_url": "https://clinicaltrials.gov/study/NCT06998407",
"title": "A Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-023 as a Single Agent, and in Combination With AVZO-021 and/or Endocrine Therapy in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-20",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Avenzo Therapeutics, Inc.",
"sponsor_slug": "avenzo-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06965127",
"publication_url": "https://clinicaltrials.gov/study/NCT06965127",
"title": "Enhancing Walking and Independence After Incomplete SCI With a Fully Implanted Neuroprosthesis",
"has_exemption": false,
"start_date": "2025-08-27",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Louis Stokes VA Medical Center",
"sponsor_slug": "louis-stokes-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06749145",
"publication_url": "https://clinicaltrials.gov/study/NCT06749145",
"title": "Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study",
"has_exemption": false,
"start_date": "2025-09-16",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06741579",
"publication_url": "https://clinicaltrials.gov/study/NCT06741579",
"title": "Mechanisms of Stimulation for Pain Alleviation",
"has_exemption": false,
"start_date": "2025-09-26",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06813820",
"publication_url": "https://clinicaltrials.gov/study/NCT06813820",
"title": "RELIVE (Randomized Evaluation of Less Invasive Ventricular Enhancement) Trial",
"has_exemption": false,
"start_date": "2025-09-29",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioVentrix",
"sponsor_slug": "bioventrix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07125222",
"publication_url": "https://clinicaltrials.gov/study/NCT07125222",
"title": "Use of Gocovri to Improve Disability Due to Radiation Encephalopathy",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07100106",
"publication_url": "https://clinicaltrials.gov/study/NCT07100106",
"title": "A Phase Ib/II Multicenter, Open-Label, Randomized Study Evaluating the Safety, Pharmacokinetics, and Activity of GDC-4198 Alone and in Combination With Giredestrant in Comparison With Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive, HER2-Negative Breast Cancer Who Have Previously Progressed During or After a CDK4/6 Inhibitor",
"has_exemption": false,
"start_date": "2025-10-07",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07118202",
"publication_url": "https://clinicaltrials.gov/study/NCT07118202",
"title": "TheraBionic P1 Device for Patients With Advanced Hepatocellular Carcinoma (HCC) Who Fail First and Second Line Therapy",
"has_exemption": false,
"start_date": "2025-10-20",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Barbara Ann Karmanos Cancer Institute",
"sponsor_slug": "barbara-ann-karmanos-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06723015",
"publication_url": "https://clinicaltrials.gov/study/NCT06723015",
"title": "Study of Tau PET Outcomes in Patients Receiving Anti-amyloid Immunotherapies",
"has_exemption": false,
"start_date": "2025-11-04",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07100782",
"publication_url": "https://clinicaltrials.gov/study/NCT07100782",
"title": "Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain",
"has_exemption": false,
"start_date": "2025-12-08",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07335601",
"publication_url": "https://clinicaltrials.gov/study/NCT07335601",
"title": "Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate MGL-3196 (Resmetirom) in Patients With MASH Who Have Undergone Liver Transplant for MASH Cirrhosis or Other Etiologies",
"has_exemption": false,
"start_date": "2025-12-29",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Madrigal Pharmaceuticals, Inc.",
"sponsor_slug": "madrigal-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06957691",
"publication_url": "https://clinicaltrials.gov/study/NCT06957691",
"title": "Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy (Fezo-ADT Trial)",
"has_exemption": false,
"start_date": "2026-01-14",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shehzad Basaria, M.D.",
"sponsor_slug": "shehzad-basaria-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07053800",
"publication_url": "https://clinicaltrials.gov/study/NCT07053800",
"title": "A Single-Arm, Open-Label, Phase II Study to Determine the Safety and Efficacy of Obecabtagene Autoleucel (Obe-cel) in Participants With Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Autolus Limited",
"sponsor_slug": "autolus-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06062888",
"publication_url": "https://clinicaltrials.gov/study/NCT06062888",
"title": "Multi-institutional Phase 2/3 Trial of Fresh Frozen Plasma (FFP) in Patients With Moderate to Severe Traumatic Brain Injury (TBI)",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06943859",
"publication_url": "https://clinicaltrials.gov/study/NCT06943859",
"title": "Ketamine for the Treatment of Opioid Use Disorder",
"has_exemption": false,
"start_date": "2026-02-04",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07518004",
"publication_url": "https://clinicaltrials.gov/study/NCT07518004",
"title": "ROME GS System Study: A Prospective, Multicenter Evaluation of Accuracy and Safety of the ROME GS System",
"has_exemption": false,
"start_date": "2026-02-12",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Senseonics, Inc.",
"sponsor_slug": "senseonics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07362017",
"publication_url": "https://clinicaltrials.gov/study/NCT07362017",
"title": "A Multicenter, Open Label Study to Investigate the Safety and Efficacy of Ponesimod in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis",
"has_exemption": false,
"start_date": "2026-02-17",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanda Pharmaceuticals",
"sponsor_slug": "vanda-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07103746",
"publication_url": "https://clinicaltrials.gov/study/NCT07103746",
"title": "Study of Ublituximab in Early, Active, Autoantibody-Positive, IMMune-MedIated NecroTizing Myopathy (AIM01)",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07273838",
"publication_url": "https://clinicaltrials.gov/study/NCT07273838",
"title": "Sodium-Glucose Cotransporter-2 Inhibitor for Amelioration of Acute Cardiorenal Syndrome: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-03-05",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07348627",
"publication_url": "https://clinicaltrials.gov/study/NCT07348627",
"title": "Opioid-Sparing Joint Replacement - Single Site Randomized Control Trial",
"has_exemption": false,
"start_date": "2026-03-19",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07477639",
"publication_url": "https://clinicaltrials.gov/study/NCT07477639",
"title": "A Phase 1/2a, Open-Label, Dose-Escalation Study to Evaluate the Safety and Preliminary Efficacy of TRX319 in Subjects With Primary or Secondary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tr1X, Inc.",
"sponsor_slug": "tr1x-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07582432",
"publication_url": "https://clinicaltrials.gov/study/NCT07582432",
"title": "An Open-label, Multi-Center, Single-arm Prospective Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex®-C Plus Standard Medical Treatment to Prevent Infections in Participants With Secondary Antibody Deficiency Associated With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-04-23",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Grifols Biologicals, LLC",
"sponsor_slug": "grifols-biologicals-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07589595",
"publication_url": "https://clinicaltrials.gov/study/NCT07589595",
"title": "A Phase 2 Randomized, Placebo-Controlled Clinical Trial to Assess the Safety and Efficacy of Donanemab in Participants With Early Cognitive Decline, at Least One Core Clinical Feature of Dementia With Lewy Bodies, and Confirmation of Alpha-Synuclein and Amyloid Co-pathology",
"has_exemption": false,
"start_date": "2026-05-20",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06957418",
"publication_url": "https://clinicaltrials.gov/study/NCT06957418",
"title": "The Alzheimer's Disease Tau Platform Clinical Trial",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Paul S. Aisen",
"sponsor_slug": "paul-s-aisen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07167966",
"publication_url": "https://clinicaltrials.gov/study/NCT07167966",
"title": "Alzheimer's Tau Platform (ATP): Regimen Specific Appendix for AADvac1",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Paul S. Aisen",
"sponsor_slug": "paul-s-aisen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07552558",
"publication_url": "https://clinicaltrials.gov/study/NCT07552558",
"title": "Phase I/II Trial of Neoadjuvant Combination of Ficerafusp Alfa, Pembrolizumab, and SBRT for Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224022",
"publication_url": "https://clinicaltrials.gov/study/NCT07224022",
"title": "NACho: A Study of Neo-Adjuvant Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "John Strickler, M.D.",
"sponsor_slug": "john-strickler-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06258525",
"publication_url": "https://clinicaltrials.gov/study/NCT06258525",
"title": "A Phase II, Open-Label Trial of S-Adenosylmethionine (SAMe) in Prevention of Oxaliplatin Associated Liver Injury",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07624526",
"publication_url": "https://clinicaltrials.gov/study/NCT07624526",
"title": "Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07652164",
"publication_url": "https://clinicaltrials.gov/study/NCT07652164",
"title": "Vanquish® Water Vapor Ablation for Grade Group 3 PrOstate CanceR: A Multicenter Single Arm Study",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Francis Medical Inc.",
"sponsor_slug": "francis-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06067802",
"publication_url": "https://clinicaltrials.gov/study/NCT06067802",
"title": "A Phase II, Escalating Dose, Open Label Study to Evaluate the Safety of Triheptanoin for the Prevention of Hypoglycemia in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jerry Vockley, MD, PhD",
"sponsor_slug": "jerry-vockley-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06891781",
"publication_url": "https://clinicaltrials.gov/study/NCT06891781",
"title": "A Prospective, Multi-center, Randomized, Double-blind, Cross Over, Clinical Trial to Compare the Safety and Effectiveness of Adaptive Versus Conventional Stimulation in Levodopa- Responsive Parkinson's Disease Treated With Bilateral Deep Brain Stimulation of the Subthalamic Nucleus",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Newronika",
"sponsor_slug": "newronika",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07539155",
"publication_url": "https://clinicaltrials.gov/study/NCT07539155",
"title": "Phase 1b/2 Study of Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic Cancer",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arkansas",
"sponsor_slug": "university-of-arkansas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594431",
"publication_url": "https://clinicaltrials.gov/study/NCT07594431",
"title": "A Randomized Phase II Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases.",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07592299",
"publication_url": "https://clinicaltrials.gov/study/NCT07592299",
"title": "A Prospective Randomized Pivotal Trial of the ALPFA Medical Prostate Ablation System Compared With Cystoscopy in Men With Symptomatic Benign Prostatic Hyperplasia",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ALPFA Medical",
"sponsor_slug": "alpfa-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07634094",
"publication_url": "https://clinicaltrials.gov/study/NCT07634094",
"title": "A Phase 2 Efficacy Trial of Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kalinski, Pawel, MD, PhD",
"sponsor_slug": "kalinski-pawel-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07102940",
"publication_url": "https://clinicaltrials.gov/study/NCT07102940",
"title": "Eftilagimod Alpha in Combination With Neoadjuvant Chemotherapy in Patients With Hormone Receptor Positive/HER2-neg Breast Cancer",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "George Washington University",
"sponsor_slug": "george-washington-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07079852",
"publication_url": "https://clinicaltrials.gov/study/NCT07079852",
"title": "The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2028-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Manoj Doss",
"sponsor_slug": "manoj-doss",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03808922",
"publication_url": "https://clinicaltrials.gov/study/NCT03808922",
"title": "A Phase III Randomized Placebo-Controlled Study to Examine the Efficacy and Safety of DAS181 for the Treatment of Lower Respiratory Tract Parainfluenza Infection in Immunocompromised Subjects",
"has_exemption": false,
"start_date": "2019-05-23",
"completion_date": "2028-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ansun Biopharma, Inc.",
"sponsor_slug": "ansun-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04056013",
"publication_url": "https://clinicaltrials.gov/study/NCT04056013",
"title": "Vicryl Rapide Versus Nonabsorbable Suture in Repair of Simple Traumatic Extremity and Trunk Lacerations in Adult Patients",
"has_exemption": false,
"start_date": "2019-09-26",
"completion_date": "2028-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04140487",
"publication_url": "https://clinicaltrials.gov/study/NCT04140487",
"title": "A Phase I/II Study of Azacitidine, Venetoclax, and Gilteritinib for Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome With an Activating FLT3 Mutation",
"has_exemption": false,
"start_date": "2019-12-17",
"completion_date": "2028-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04209686",
"publication_url": "https://clinicaltrials.gov/study/NCT04209686",
"title": "Phase 2 Study of Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma",
"has_exemption": false,
"start_date": "2020-07-31",
"completion_date": "2028-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}