HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 50008,
"recordsTotal": 50008,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&start=41700",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&start=41100",
"results": [
{
"registry_id": "NCT07231523",
"publication_url": "https://clinicaltrials.gov/study/NCT07231523",
"title": "Perioperative Efficacy and Safety of Efgartigimod Versus Intravenous Immunoglobulin for Thymoma Associated Myasthenia Gravis: a Prospective, Multicenter, Randomized Controlled Study",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Zhongshan Hospital",
"sponsor_slug": "shanghai-zhongshan-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220525",
"publication_url": "https://clinicaltrials.gov/study/NCT07220525",
"title": "Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07321704",
"publication_url": "https://clinicaltrials.gov/study/NCT07321704",
"title": "Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease With Myriad Extracellular Matrix Implantation",
"has_exemption": false,
"start_date": "2026-02-17",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yosef Nasseri, MD",
"sponsor_slug": "yosef-nasseri-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07101640",
"publication_url": "https://clinicaltrials.gov/study/NCT07101640",
"title": "Pharmacokinetics, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia",
"has_exemption": false,
"start_date": "2026-02-23",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07263035",
"publication_url": "https://clinicaltrials.gov/study/NCT07263035",
"title": "Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Lakeland Regional Health Systems, Inc.",
"sponsor_slug": "lakeland-regional-health-systems-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07401225",
"publication_url": "https://clinicaltrials.gov/study/NCT07401225",
"title": "Transcranial Magnetic Stimulation as Treatment for Persistent PTSD in Texas Youth",
"has_exemption": false,
"start_date": "2026-05-09",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07211035",
"publication_url": "https://clinicaltrials.gov/study/NCT07211035",
"title": "A Pivotal Study to Evaluate the Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and Arteriovenous Fistula Maturation",
"has_exemption": false,
"start_date": "2026-05-12",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Amplifi Vascular, Inc.",
"sponsor_slug": "amplifi-vascular-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07249346",
"publication_url": "https://clinicaltrials.gov/study/NCT07249346",
"title": "An Open Label, Non-Randomized, Multi-Center Pilot Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for GVHD Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Hannah Choe, MD",
"sponsor_slug": "hannah-choe-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07682831",
"publication_url": "https://clinicaltrials.gov/study/NCT07682831",
"title": "Machine Learning Analysis of Expanded Two-photon Imaging of Skin Biopsy Specimens",
"has_exemption": false,
"start_date": "2026-06-24",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07056699",
"publication_url": "https://clinicaltrials.gov/study/NCT07056699",
"title": "Protocol V: San Antonio Site Sub Study: Can Pioglitazone Block SGLT2 Inhibitor-induced Stimulation of Lipolysis, Ketone Production and Liver Glucose Production in Type I Diabetic Patients",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07357675",
"publication_url": "https://clinicaltrials.gov/study/NCT07357675",
"title": "A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "EBI Anti Sepsis BV",
"sponsor_slug": "ebi-anti-sepsis-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07553364",
"publication_url": "https://clinicaltrials.gov/study/NCT07553364",
"title": "Feasibility of Using Alpha Phase-Locked Auditory Stimulation for Insomnia Symptoms in People With Depression",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04003285",
"publication_url": "https://clinicaltrials.gov/study/NCT04003285",
"title": "Novel Regenerative Therapeutic in Chronic Complex TBI",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06655142",
"publication_url": "https://clinicaltrials.gov/study/NCT06655142",
"title": "Prospective Matched Control Feasibility Study to Determine the Capacity of the Onco-Seraph 100 Microbind® Affinity Blood Filter ( ONCObind Procedure) to Remove Circulating Tumor Cells From the Blood in Patients With Either Metastatic Pancreatic Adenocarcinoma or Metastatic Colorectal Carcinoma",
"has_exemption": false,
"start_date": "2027-01-15",
"completion_date": "2027-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "ExThera Medical Corporation",
"sponsor_slug": "exthera-medical-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05263206",
"publication_url": "https://clinicaltrials.gov/study/NCT05263206",
"title": "Master Protocol of Two Randomized, Double Blind, Placebo-controlled, Multi-center, Parallel Group Studies to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Chronic Pruritus of Unknown Origin (CPUO)",
"has_exemption": false,
"start_date": "2022-02-15",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04783857",
"publication_url": "https://clinicaltrials.gov/study/NCT04783857",
"title": "Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children",
"has_exemption": false,
"start_date": "2022-04-14",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05868265",
"publication_url": "https://clinicaltrials.gov/study/NCT05868265",
"title": "Neoadjuvant Enfortumab Vedotin in High-Grade Urothelial Carcinoma of the Upper Urinary Tract (Including Ureter and Renal Pelvis)",
"has_exemption": false,
"start_date": "2023-06-02",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06401356",
"publication_url": "https://clinicaltrials.gov/study/NCT06401356",
"title": "An Open-Label, Multicenter, Extension Study for Patients Previously Enrolled in Studies With Pelabresib",
"has_exemption": false,
"start_date": "2024-08-13",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04679844",
"publication_url": "https://clinicaltrials.gov/study/NCT04679844",
"title": "A Prospective, Randomized, Multi-Center Study to Assess the Safety and Performance of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers (DBX or Grafton) Mixed With Local Autograft in Patients Undergoing One to Two-Level Instrumented Posterolateral Lumbar/Thoracolumbar Fusion (PLF)",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2027-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Kuros Biosurgery AG",
"sponsor_slug": "kuros-biosurgery-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06840392",
"publication_url": "https://clinicaltrials.gov/study/NCT06840392",
"title": "A Randomized, Double-blind, Double-dummy, Placebo-controlled, Multicenter, Phase 3 Study Assessing the Efficacy, Safety, and Tolerability of 2 Doses of Remibrutinib Over a 68-week Treatment Period in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE-2)",
"has_exemption": false,
"start_date": "2025-03-20",
"completion_date": "2027-06-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05957913",
"publication_url": "https://clinicaltrials.gov/study/NCT05957913",
"title": "Effects of Antiviral Therapies on Epstein-Barr Virus Replication",
"has_exemption": false,
"start_date": "2023-06-05",
"completion_date": "2027-06-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06962306",
"publication_url": "https://clinicaltrials.gov/study/NCT06962306",
"title": "Perioperative Methadone Use for Cleft Palate Repair: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2027-06-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05329649",
"publication_url": "https://clinicaltrials.gov/study/NCT05329649",
"title": "A Phase 3 Study to Evaluate the Safety and Efficacy of a Single Dose of CTX001 in Pediatric Subjects With Severe Sickle Cell Disease",
"has_exemption": false,
"start_date": "2022-05-02",
"completion_date": "2027-06-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05934448",
"publication_url": "https://clinicaltrials.gov/study/NCT05934448",
"title": "A Phase II Trial of Pembrolizumab in Combination With Chimeric Antigen Receptor Therapy in Patients With Relapsed/Refractory Primary Mediastinal B-cell Lymphoma",
"has_exemption": false,
"start_date": "2023-11-15",
"completion_date": "2027-06-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Jennifer Crombie, MD",
"sponsor_slug": "jennifer-crombie-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06653192",
"publication_url": "https://clinicaltrials.gov/study/NCT06653192",
"title": "Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction: An Open-label, Multicenter Randomized Trial (CARPEDIEM Trial)",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2027-06-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital Universitari de Bellvitge",
"sponsor_slug": "hospital-universitari-de-bellvitge",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05019716",
"publication_url": "https://clinicaltrials.gov/study/NCT05019716",
"title": "A Phase 1 Study of the Bromodomain Inhibitor ZEN003694 in Combination With Platinum-based Chemotherapy in Patients With NUT Carcinoma",
"has_exemption": false,
"start_date": "2022-07-13",
"completion_date": "2027-06-07",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06932263",
"publication_url": "https://clinicaltrials.gov/study/NCT06932263",
"title": "A Phase IIb, Multicentre, Double-blind, Placebo-controlled Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adult Participants With Uncontrolled Asthma on Medium-to High Dose Inhaled Corticosteroids",
"has_exemption": false,
"start_date": "2025-03-26",
"completion_date": "2027-06-07",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07348692",
"publication_url": "https://clinicaltrials.gov/study/NCT07348692",
"title": "A Phase 3, Randomized, Modified Double-blind, Active-controlled, Parallel-group, Lot-to-lot Consistency, 4-arm Study to Investigate the Safety and Immunogenicity of a 4-dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers",
"has_exemption": false,
"start_date": "2026-01-20",
"completion_date": "2027-06-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06408935",
"publication_url": "https://clinicaltrials.gov/study/NCT06408935",
"title": "A Phase 3b, Open-label, Multicenter Study to Evaluate Transmural Healing and Disease Modifying Effect of Guselkumab in Crohn's Disease Patients",
"has_exemption": false,
"start_date": "2024-04-17",
"completion_date": "2027-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen-Cilag Ltd.",
"sponsor_slug": "janssen-cilag-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06227910",
"publication_url": "https://clinicaltrials.gov/study/NCT06227910",
"title": "A Randomized, Double-Blind, Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab and Oral Placebo for Induction Followed by Intravenous Vedolizumab Monotherapy for Maintenance in the Treatment of Adults With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2025-01-02",
"completion_date": "2027-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02584933",
"publication_url": "https://clinicaltrials.gov/study/NCT02584933",
"title": "An Open-label, Multi-center, Phase IV Roll-over Study in Patients With ALK Positive Malignancies Who Have Completed a Novartis-sponsored Ceritinib (LDK378) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Ceritinib",
"has_exemption": false,
"start_date": "2015-12-11",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05477563",
"publication_url": "https://clinicaltrials.gov/study/NCT05477563",
"title": "A Phase 3b Study to Evaluate Efficacy and Safety of a Single Dose of Autologous CRISPR Cas9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells (CTX001) in Subjects With Transfusion-Dependent β-Thalassemia or Severe Sickle Cell Disease",
"has_exemption": false,
"start_date": "2022-08-02",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05912244",
"publication_url": "https://clinicaltrials.gov/study/NCT05912244",
"title": "A Phase II Study of IO102/IO103 and Nivolumab-relatlimab Fixed Dose Combination in Untreated, Unresectable Stage III/IV Melanoma",
"has_exemption": false,
"start_date": "2023-06-09",
"completion_date": "2027-06-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03314974",
"publication_url": "https://clinicaltrials.gov/study/NCT03314974",
"title": "Myeloablative Allogeneic Hematopoietic Cell Transplantation Using a Related or Unrelated Donor for the Treatment of Hematological Diseases",
"has_exemption": false,
"start_date": "2018-03-30",
"completion_date": "2027-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05419076",
"publication_url": "https://clinicaltrials.gov/study/NCT05419076",
"title": "A Single Arm Phase II Study Assessing Efficacy of Stereotactic Radiosurgery (SRS) for Brain Metastasis (BM) From Small Cell Lung Cancer (SCLC)",
"has_exemption": false,
"start_date": "2022-06-10",
"completion_date": "2027-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04199741",
"publication_url": "https://clinicaltrials.gov/study/NCT04199741",
"title": "Immuno-PET Imaging of Neuroendocrine Tumors Using 89Zr-DFO-SC16.56, a DLL3-targeting Monoclonal Antibody",
"has_exemption": false,
"start_date": "2019-12-11",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05319730",
"publication_url": "https://clinicaltrials.gov/study/NCT05319730",
"title": "A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer Previously Exposed to PD-1/PD-L1 Treatment (KEYMAKER-U06): Substudy 06B",
"has_exemption": false,
"start_date": "2023-05-16",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06307652",
"publication_url": "https://clinicaltrials.gov/study/NCT06307652",
"title": "A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared With Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients With Heart Failure and Impaired Kidney Function",
"has_exemption": false,
"start_date": "2024-04-12",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07108387",
"publication_url": "https://clinicaltrials.gov/study/NCT07108387",
"title": "A Randomized Study of Tocilizumab Discontinuation for Patients With Giant Cell Arteritis in Remission (AGA01)",
"has_exemption": false,
"start_date": "2026-01-05",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07202546",
"publication_url": "https://clinicaltrials.gov/study/NCT07202546",
"title": "A Phase 2b Randomized, Open-Label Active Controlled Study Evaluating the Safety and Efficacy of Oral VH4524184 Coadministered With Emtricitabine and Tenofovir Alafenamide in Treatment Naive Viremic Persons With HIV-1 (INNOVATE Study)",
"has_exemption": false,
"start_date": "2026-02-11",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "ViiV Healthcare",
"sponsor_slug": "viiv-healthcare",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07738276",
"publication_url": "https://clinicaltrials.gov/study/NCT07738276",
"title": "Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity: A Double-Blinded Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-07-18",
"completion_date": "2027-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Shahid Beheshti University of Medical Sciences",
"sponsor_slug": "shahid-beheshti-university-of-medical-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07405151",
"publication_url": "https://clinicaltrials.gov/study/NCT07405151",
"title": "A Phase 2 Open-Label, Umbrella Platform Design Study of Investigational Agent(s) in Participants With 2L/3L Unresectable Locally Advanced or Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06F",
"has_exemption": false,
"start_date": "2026-03-27",
"completion_date": "2027-06-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07266441",
"publication_url": "https://clinicaltrials.gov/study/NCT07266441",
"title": "A Phase 2, Open-label Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) Who Have Received at Least 3 Prior Lines of Therapy Including a PI, an IMiD, and an Anti-CD38 Antibody",
"has_exemption": false,
"start_date": "2026-02-08",
"completion_date": "2027-06-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07012031",
"publication_url": "https://clinicaltrials.gov/study/NCT07012031",
"title": "A Phase I/II Study Evaluating the Safety, Tolerability, and Efficacy of Sotorasib Plus Trastuzumab Deruxtecan in Patients With Advanced Non-Small Cell Lung Cancer With a KRASG12C Mutation",
"has_exemption": false,
"start_date": "2026-06-17",
"completion_date": "2027-06-14",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04936529",
"publication_url": "https://clinicaltrials.gov/study/NCT04936529",
"title": "Phase II Trial of a Bivalent Vaccine With the Immunological Adjuvant OPT-821 (QS-21), in Combination With Oral β-glucan and Randomization of GM-CSF, for High-risk Neuroblastoma",
"has_exemption": false,
"start_date": "2021-08-02",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06047535",
"publication_url": "https://clinicaltrials.gov/study/NCT06047535",
"title": "Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First Complete Response. A Single-Arm, Multicenter Clinical Trial",
"has_exemption": false,
"start_date": "2023-10-31",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "SciClone Pharmaceuticals",
"sponsor_slug": "sciclone-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06333509",
"publication_url": "https://clinicaltrials.gov/study/NCT06333509",
"title": "A Phase 1/2 Open Label Study to Evaluate the Safety and Efficacy of CT071, an Autologous Anti-GPRC5D CAR T, in Relapsed/Refractory Multiple Myeloma (RRMM) or Relapsed/Refractory Primary Plasma Cell Leukemia (RRpPCL)",
"has_exemption": false,
"start_date": "2024-04-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "CARsgen Therapeutics Co., Ltd.",
"sponsor_slug": "carsgen-therapeutics-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06305715",
"publication_url": "https://clinicaltrials.gov/study/NCT06305715",
"title": "Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06422923",
"publication_url": "https://clinicaltrials.gov/study/NCT06422923",
"title": "A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Temporal Lobe Epilepsy (MTLE)",
"has_exemption": false,
"start_date": "2024-11-14",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurona Therapeutics",
"sponsor_slug": "neurona-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06872892",
"publication_url": "https://clinicaltrials.gov/study/NCT06872892",
"title": "A Phase III, Randomised, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of BI 1291583 2.5 mg Administered Once Daily for up to 76 Weeks in Patients With Bronchiectasis (The AIRTIVITY™ Study)",
"has_exemption": false,
"start_date": "2025-06-09",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06735885",
"publication_url": "https://clinicaltrials.gov/study/NCT06735885",
"title": "Stanford-Matter Neuroscience High-Resolution fMRI Advanced Neurofeedback Feasibility Trial (fMRI Neurofeedback) Medical",
"has_exemption": false,
"start_date": "2025-08-12",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07133633",
"publication_url": "https://clinicaltrials.gov/study/NCT07133633",
"title": "A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tulisokibart in Participants With Radiographic Axial Spondyloarthritis (Ankylosing Spondylitis)",
"has_exemption": false,
"start_date": "2025-09-26",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06517797",
"publication_url": "https://clinicaltrials.gov/study/NCT06517797",
"title": "Phase IIb Placebo-Controlled Double-Blind Randomized Parallel Groups Study to Determine the Efficacy and Safety of S1B-509 for Weight Loss",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "S1 Biopharma, Inc.",
"sponsor_slug": "s1-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07239336",
"publication_url": "https://clinicaltrials.gov/study/NCT07239336",
"title": "A Phase II, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate The Efficacy and Safety of DONQ52 in Active Celiac Disease Patients Who Have Duodenal Mucosal Damage and Persistent Symptoms Despite Attempting A Gluten-free Diet (DAISY STUDY)",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Chugai Pharmaceutical",
"sponsor_slug": "chugai-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07452549",
"publication_url": "https://clinicaltrials.gov/study/NCT07452549",
"title": "Safety and Effectiveness of TETRANITE Bone Adhesive for Cranial Flap Fixation Compared to Traditional Metal Hardware",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "RevBio",
"sponsor_slug": "revbio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07574541",
"publication_url": "https://clinicaltrials.gov/study/NCT07574541",
"title": "Phase II Trial of a Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance",
"has_exemption": false,
"start_date": "2026-08-25",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06137638",
"publication_url": "https://clinicaltrials.gov/study/NCT06137638",
"title": "A Placebo-controlled, Double-blind, Randomized Trial to Evaluate the Efficacy of ENA-001 in Preventing Postoperative Respiratory Depression",
"has_exemption": false,
"start_date": "2026-12-15",
"completion_date": "2027-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Enalare Therapeutics Inc.",
"sponsor_slug": "enalare-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06282042",
"publication_url": "https://clinicaltrials.gov/study/NCT06282042",
"title": "Early Transcatheter Mitral Valve Repair After Myocardial Infarction",
"has_exemption": false,
"start_date": "2024-12-24",
"completion_date": "2027-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Fundación para la Investigación Biosanitaria del Principado de Asturias",
"sponsor_slug": "fundacion-para-la-investigacion-biosanitaria-del-principado-de-asturias",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07266558",
"publication_url": "https://clinicaltrials.gov/study/NCT07266558",
"title": "A Phase 4, Randomized, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of mRNA-1283 And mRNA-1273 Variant-Containing Formulation in Adults 50 to 64 Years of Age Without Underlying Conditions That Put Them at High Risk for Severe Outcomes From COVID-19",
"has_exemption": false,
"start_date": "2025-11-26",
"completion_date": "2027-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "ModernaTX, Inc.",
"sponsor_slug": "modernatx-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07676435",
"publication_url": "https://clinicaltrials.gov/study/NCT07676435",
"title": "A PHASE II, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE ONGOING LUNG DECLINE WITH AGE INTENSIFIED RESPONSE (OLD AIR)",
"has_exemption": false,
"start_date": "2026-06-17",
"completion_date": "2027-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06620523",
"publication_url": "https://clinicaltrials.gov/study/NCT06620523",
"title": "Efficacy of Mitochondrial Directed Therapy in Prevention of Cardiac Surgery Associated AKI Prevent Cardiac Surgery Associated AKI Trial (Prevent CSA-AKI Trial)",
"has_exemption": false,
"start_date": "2024-07-18",
"completion_date": "2027-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "George Washington University",
"sponsor_slug": "george-washington-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06980077",
"publication_url": "https://clinicaltrials.gov/study/NCT06980077",
"title": "UCLA L-11: A Phase II Trial of Ivonescimab for Previously Treated Thymic Carcinoma",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2027-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07476339",
"publication_url": "https://clinicaltrials.gov/study/NCT07476339",
"title": "A Multi-Center, Single-Arm, Open-Label, Prospective, Phase 4 Study to Investigate the Safety and Efficacy of Rapidly Restarting Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide (B/F/TAF) in Viremic and Virologically-Suppressed Male and Female HIV-Positive Patients Aged ≥18 Years Who Are Treatment-Experienced and Returning to Care After Experiencing a Treatment Interruption of ≥12 Weeks",
"has_exemption": false,
"start_date": "2026-06-17",
"completion_date": "2027-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "CAN Community Health",
"sponsor_slug": "can-community-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220772",
"publication_url": "https://clinicaltrials.gov/study/NCT07220772",
"title": "An Open-Label Study of Mibavademab (REGN4461), a Leptin Receptor Agonist, for the Treatment of Monogenic Obesity Due to Biallelic Loss of Function Variants of the LEP Gene",
"has_exemption": false,
"start_date": "2026-02-09",
"completion_date": "2027-06-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07732374",
"publication_url": "https://clinicaltrials.gov/study/NCT07732374",
"title": "Assessing Follow-Up Effects Post-Discontinuation of Hyperbaric Oxygen Therapy on Cognitive Function, Mental Health, and Quality of Life in Veterans",
"has_exemption": false,
"start_date": "2026-06-18",
"completion_date": "2027-06-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Summit Hyperbarics and Wellness",
"sponsor_slug": "summit-hyperbarics-and-wellness",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05758545",
"publication_url": "https://clinicaltrials.gov/study/NCT05758545",
"title": "Concurrent Optical and Magnetic Stimulation (COMS) for Treatment of Refractory Diabetic Foot Ulcer; a Prospective Randomized, Sham-controlled, Double-blinded, Pivotal Clinical Trial",
"has_exemption": false,
"start_date": "2023-06-19",
"completion_date": "2027-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Piomic Medical",
"sponsor_slug": "piomic-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06698822",
"publication_url": "https://clinicaltrials.gov/study/NCT06698822",
"title": "A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA",
"has_exemption": false,
"start_date": "2025-03-10",
"completion_date": "2027-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04238624",
"publication_url": "https://clinicaltrials.gov/study/NCT04238624",
"title": "A Pilot Study of the Addition of Cemiplimab, an Antibody to PD-1, to the Treatment of Subjects With BRAF-Mutant Anaplastic Thyroid Cancer Who Are No Longer Responding to Dabrafenib and Trametinib",
"has_exemption": false,
"start_date": "2020-01-20",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05422534",
"publication_url": "https://clinicaltrials.gov/study/NCT05422534",
"title": "Role of Mitochondrial Dysfunction in the Response to Exercise in Patients With Advance Kidney Disease",
"has_exemption": false,
"start_date": "2023-06-01",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06105892",
"publication_url": "https://clinicaltrials.gov/study/NCT06105892",
"title": "Eye Recovery Automation for Post Injury Dysfunction",
"has_exemption": false,
"start_date": "2023-10-23",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "New Jersey Institute of Technology",
"sponsor_slug": "new-jersey-institute-of-technology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06598007",
"publication_url": "https://clinicaltrials.gov/study/NCT06598007",
"title": "A Phase 1/2 First-In-Human, Open-Label, Multicenter, Dose Escalation and Dose Expansion Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CT3001 in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2024-09-20",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Crossignal Therapeutics, Inc.",
"sponsor_slug": "crossignal-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07163273",
"publication_url": "https://clinicaltrials.gov/study/NCT07163273",
"title": "Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-06-20",
"completion_date": "2027-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06676319",
"publication_url": "https://clinicaltrials.gov/study/NCT06676319",
"title": "A Randomized, Phase 2, Double-blind, Placebo-controlled, Parallel-group, 2-arm Study to Investigate the Efficacy, Safety, and Tolerability of Subcutaneous Lunsekimig (SAR443765) in Adult Participants With High-risk Asthma Who Are Not Currently Eligible for Biologic Treatment",
"has_exemption": false,
"start_date": "2024-11-07",
"completion_date": "2027-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06690398",
"publication_url": "https://clinicaltrials.gov/study/NCT06690398",
"title": "A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Lumateperone in the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients 5 to 17 Years of Age",
"has_exemption": false,
"start_date": "2024-11-22",
"completion_date": "2027-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06706674",
"publication_url": "https://clinicaltrials.gov/study/NCT06706674",
"title": "A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Lumateperone in the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients 5 to 17 Years of Age",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2027-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06796907",
"publication_url": "https://clinicaltrials.gov/study/NCT06796907",
"title": "A Phase 1/2 Randomized Multi-Cohort Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan in Combination With Anti-Cancer Agents in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-03-04",
"completion_date": "2027-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04998552",
"publication_url": "https://clinicaltrials.gov/study/NCT04998552",
"title": "Safety and Efficacy of Cyberknife in Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma: Open Label Prospective Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Capital Health System, Inc",
"sponsor_slug": "capital-health-system-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05126277",
"publication_url": "https://clinicaltrials.gov/study/NCT05126277",
"title": "A Randomized, Double-blind, Parallel Group, Placebo-controlled, Multicenter Phase 3 Trial to Evaluate Efficacy, Safety and Tolerability of Ianalumab on Top of Standard-of-care Therapy in Participants With Active Lupus Nephritis (SIRIUS-LN).",
"has_exemption": false,
"start_date": "2022-07-14",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06995352",
"publication_url": "https://clinicaltrials.gov/study/NCT06995352",
"title": "Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery: A Randomized, Observer and Participant Masked, Active Control, Non-Inferiority Study",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07182240",
"publication_url": "https://clinicaltrials.gov/study/NCT07182240",
"title": "Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07431853",
"publication_url": "https://clinicaltrials.gov/study/NCT07431853",
"title": "A PHASE 2, RANDOMIZED, DOUBLE-BLIND, CLINICAL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF MRNA VACCINES AGAINST INFLUENZA IN ADULTS 18 YEARS OF AGE AND OLDER",
"has_exemption": false,
"start_date": "2026-02-23",
"completion_date": "2027-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03731260",
"publication_url": "https://clinicaltrials.gov/study/NCT03731260",
"title": "A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indolent and Smoldering Systemic Mastocytosis With Symptoms Inadequately Controlled With Standard Therapy",
"has_exemption": false,
"start_date": "2019-04-16",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Blueprint Medicines Corporation",
"sponsor_slug": "blueprint-medicines-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05445609",
"publication_url": "https://clinicaltrials.gov/study/NCT05445609",
"title": "A Single Arm Study of Vidutolimod (CMP-001) With Nivolumab in Patients With Metastatic Castration Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2023-06-07",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07311564",
"publication_url": "https://clinicaltrials.gov/study/NCT07311564",
"title": "A Phase 2, Randomized, Placebo-controlled, Double-blind Clinical Study to Evaluate Efficacy and Safety of LAD603 in Adult Subjects With Severe to Very Severe Alopecia Areata",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Almirall, S.A.",
"sponsor_slug": "almirall-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07665294",
"publication_url": "https://clinicaltrials.gov/study/NCT07665294",
"title": "CURVE-UC: A Pragmatic Randomized, Double-blind, Placebo Controlled, Treat-through, Multi-site Pragmatic Interventional Study to Evaluate the Efficacy and Safety of Combination Curcumin-QingDai (CurQD) With Vedolizumab in Moderate to Severe Ulcerative Colitis (UC)",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2027-06-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Ryan C Ungaro",
"sponsor_slug": "ryan-c-ungaro",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03523975",
"publication_url": "https://clinicaltrials.gov/study/NCT03523975",
"title": "Phase I/II Multi-site Study Evaluating the MTD, Safety and Efficacy of the Combination Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2018-12-24",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06147986",
"publication_url": "https://clinicaltrials.gov/study/NCT06147986",
"title": "A Phase IIa, Dose-Escalation Followed by Randomized, Open-Label, Parallel-Group Study to Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells As an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients",
"has_exemption": false,
"start_date": "2023-09-24",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Ever Supreme Bio Technology Co., Ltd.",
"sponsor_slug": "ever-supreme-bio-technology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06655883",
"publication_url": "https://clinicaltrials.gov/study/NCT06655883",
"title": "A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Suvorexant for the Treatment of Insomnia in Participants With Opioid Use Disorder",
"has_exemption": false,
"start_date": "2025-10-09",
"completion_date": "2027-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06473779",
"publication_url": "https://clinicaltrials.gov/study/NCT06473779",
"title": "A Multicentre, Randomised, Open-Label, Parallel-Group, Phase IIIb Study to Assess the Potential for Tezepelumab-treated Patients With Severe Asthma to Reduce Background Therapy While Sustaining Asthma Control and Clinical Remission",
"has_exemption": false,
"start_date": "2024-09-30",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06578741",
"publication_url": "https://clinicaltrials.gov/study/NCT06578741",
"title": "GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study",
"has_exemption": false,
"start_date": "2024-11-25",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215390",
"publication_url": "https://clinicaltrials.gov/study/NCT07215390",
"title": "A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneration",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Apellis Pharmaceuticals, Inc.",
"sponsor_slug": "apellis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06418958",
"publication_url": "https://clinicaltrials.gov/study/NCT06418958",
"title": "In Vivo Temperature Changes Caused by Exposure to Short- and Long-wavelengths",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2027-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05776914",
"publication_url": "https://clinicaltrials.gov/study/NCT05776914",
"title": "Efficacy and Safety of Proteolytic Activity-Guided Fecal Microbiota Transplantation for Irritable Bowel Syndrome (PRAGMAT Trial)",
"has_exemption": false,
"start_date": "2024-04-15",
"completion_date": "2027-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Madhusudan (Madhu) Grover, MBBS",
"sponsor_slug": "madhusudan-madhu-grover-mbbs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07681102",
"publication_url": "https://clinicaltrials.gov/study/NCT07681102",
"title": "Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke",
"has_exemption": false,
"start_date": "2026-02-10",
"completion_date": "2027-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Magnetic Tides",
"sponsor_slug": "magnetic-tides",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06065449",
"publication_url": "https://clinicaltrials.gov/study/NCT06065449",
"title": "A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases",
"has_exemption": false,
"start_date": "2024-01-24",
"completion_date": "2027-06-27",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04112641",
"publication_url": "https://clinicaltrials.gov/study/NCT04112641",
"title": "Alleviation by NIAGEN of Persistent Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors",
"has_exemption": false,
"start_date": "2020-02-19",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Donna Hammond, PhD",
"sponsor_slug": "donna-hammond-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05513859",
"publication_url": "https://clinicaltrials.gov/study/NCT05513859",
"title": "Towards In-Vivo, Intraoperative Image Guided Brain Tumor Margin Assessment With Quantitative Oblique Back Illumination Microscopy",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06045754",
"publication_url": "https://clinicaltrials.gov/study/NCT06045754",
"title": "An Open-Label, Phase 4 Study to Evaluate the Efficacy and Safety of Dual Targeted Therapy With Vedolizumab Intravenous (IV) and Adalimumab Subcutaneous (SC) or Vedolizumab IV and Ustekinumab IV/SC in Moderate to Severe Crohn's Disease (CD)",
"has_exemption": false,
"start_date": "2024-04-18",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06887829",
"publication_url": "https://clinicaltrials.gov/study/NCT06887829",
"title": "The Randomized Clinical Trial of Low-Dose Radiotherapy for Knee Osteoarthritis",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07140913",
"publication_url": "https://clinicaltrials.gov/study/NCT07140913",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Individuals With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine",
"has_exemption": false,
"start_date": "2025-10-08",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07321873",
"publication_url": "https://clinicaltrials.gov/study/NCT07321873",
"title": "A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of JNJ-88545223 For the Treatment of Participants With Active Psoriatic Arthritis",
"has_exemption": false,
"start_date": "2026-01-15",
"completion_date": "2027-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03190941",
"publication_url": "https://clinicaltrials.gov/study/NCT03190941",
"title": "A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients",
"has_exemption": false,
"start_date": "2017-09-21",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05873205",
"publication_url": "https://clinicaltrials.gov/study/NCT05873205",
"title": "Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation",
"has_exemption": false,
"start_date": "2023-07-21",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05958381",
"publication_url": "https://clinicaltrials.gov/study/NCT05958381",
"title": "Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation",
"has_exemption": false,
"start_date": "2023-10-18",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas at Dallas",
"sponsor_slug": "the-university-of-texas-at-dallas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325526",
"publication_url": "https://clinicaltrials.gov/study/NCT07325526",
"title": "A Phase IIa Double-blind, Placebo-controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 3802876 in Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatohepatitis (MASH)",
"has_exemption": false,
"start_date": "2026-02-27",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07191379",
"publication_url": "https://clinicaltrials.gov/study/NCT07191379",
"title": "Self-administered Subcutaneous Daratumumab in Patients With Multiple Myeloma. An Open Label, Phase Four, Prospective, Non-randomized, Sponsor-initiated Multicenter Feasibility Study",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2027-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Odense University Hospital",
"sponsor_slug": "odense-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00412594",
"publication_url": "https://clinicaltrials.gov/study/NCT00412594",
"title": "Phase II Study of 2-Chlorodeoxyadenosine (2CDA) Followed by Rituximab in Hairy Cell Leukemia",
"has_exemption": false,
"start_date": "2004-06-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT00950430",
"publication_url": "https://clinicaltrials.gov/study/NCT00950430",
"title": "Brain Amyloid Imaging With Pittsburgh Compound B in Normal Aging, Mild Cognitive Impairment, and Dementia",
"has_exemption": false,
"start_date": "2008-04-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01153035",
"publication_url": "https://clinicaltrials.gov/study/NCT01153035",
"title": "ABLATE Registry: Radiofrequency Ablation After Breast Lumpectomy (eRFA) Added To Extend Intraoperative Margins in the Treatment of Breast Cancer",
"has_exemption": false,
"start_date": "2010-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arkansas",
"sponsor_slug": "university-of-arkansas",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02098265",
"publication_url": "https://clinicaltrials.gov/study/NCT02098265",
"title": "A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device",
"has_exemption": false,
"start_date": "2010-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01141309",
"publication_url": "https://clinicaltrials.gov/study/NCT01141309",
"title": "Phase II Study Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer",
"has_exemption": false,
"start_date": "2010-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03105518",
"publication_url": "https://clinicaltrials.gov/study/NCT03105518",
"title": "Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction",
"has_exemption": false,
"start_date": "2011-03-01",
"completion_date": "2027-06-30",
"has_results": true,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "reported",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01659203",
"publication_url": "https://clinicaltrials.gov/study/NCT01659203",
"title": "Phase I/II Trial of Pre-Operative Image Guided Intensity Modulated Proton Radiation Therapy (IMPT) or Photon (IMRT) With Simultaneously Integrated Boost to the High Risk Margin for Retroperitoneal Sarcomas",
"has_exemption": false,
"start_date": "2012-12-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01892397",
"publication_url": "https://clinicaltrials.gov/study/NCT01892397",
"title": "Pilot Study of Optune (NovoTTF-100A) for Recurrent Atypical and Anaplastic Meningioma",
"has_exemption": false,
"start_date": "2013-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01873326",
"publication_url": "https://clinicaltrials.gov/study/NCT01873326",
"title": "Randomized Phase II Trial of Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-Risk Germ Cell Tumors",
"has_exemption": false,
"start_date": "2013-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02400359",
"publication_url": "https://clinicaltrials.gov/study/NCT02400359",
"title": "Lorcaserin in Obesity: Identification of CNS Targets Using fMRI",
"has_exemption": false,
"start_date": "2014-10-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02427620",
"publication_url": "https://clinicaltrials.gov/study/NCT02427620",
"title": "A Phase II Study of Ibrutinib Plus Rituximab With Hyper-CVAD Consolidation in Newly Diagnosed Young Patients With Mantle Cell Lymphoma: A Window Period for Bioimmunotherapy Before Chemotherapy",
"has_exemption": false,
"start_date": "2015-06-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02392442",
"publication_url": "https://clinicaltrials.gov/study/NCT02392442",
"title": "Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in Humans",
"has_exemption": false,
"start_date": "2015-06-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institutes of Health Clinical Center (CC)",
"sponsor_slug": "national-institutes-of-health-clinical-center-cc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02494700",
"publication_url": "https://clinicaltrials.gov/study/NCT02494700",
"title": "Ultra Low Dose 4 Gy Orbital Radiation for Definitive Therapy of Indolent B Cell Lymphoma",
"has_exemption": false,
"start_date": "2015-07-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02568267",
"publication_url": "https://clinicaltrials.gov/study/NCT02568267",
"title": "An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements",
"has_exemption": false,
"start_date": "2015-11-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02815917",
"publication_url": "https://clinicaltrials.gov/study/NCT02815917",
"title": "Evaluation of D3 Receptor Occupancy Using [18F]FLUORTRIOPRIDE ([18F]FTP) PET/CT",
"has_exemption": false,
"start_date": "2016-06-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02945501",
"publication_url": "https://clinicaltrials.gov/study/NCT02945501",
"title": "Transcranial Electrical Stimulation at Slow Oscillation Frequency During NREM Sleep: An Assessment of Effects on the Restorative Properties of Sleep",
"has_exemption": false,
"start_date": "2016-10-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "U.S. Army Medical Research and Development Command",
"sponsor_slug": "us-army-medical-research-and-development-command",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02886585",
"publication_url": "https://clinicaltrials.gov/study/NCT02886585",
"title": "Phase II Trial of Pembrolizumab in Central Nervous System Metastases From Multiple Histologies",
"has_exemption": false,
"start_date": "2016-10-31",
"completion_date": "2027-06-30",
"has_results": true,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "reported",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02935361",
"publication_url": "https://clinicaltrials.gov/study/NCT02935361",
"title": "A Phase I/II Multicenter Study Combining Guadecitabine, a DNA Methyltransferase Inhibitor, With Atezolizumab, an Immune Checkpoint Inhibitor, in Patients With Intermediate or High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia",
"has_exemption": false,
"start_date": "2016-11-02",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02944500",
"publication_url": "https://clinicaltrials.gov/study/NCT02944500",
"title": "Saxenda: Underlying Mechanisms and Clinical Outcomes",
"has_exemption": false,
"start_date": "2016-11-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02899052",
"publication_url": "https://clinicaltrials.gov/study/NCT02899052",
"title": "A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2017-01-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02649166",
"publication_url": "https://clinicaltrials.gov/study/NCT02649166",
"title": "Closing the Loop on Tremor: A Responsive Deep Brain Stimulator for the Treatment of Essential Tremor",
"has_exemption": false,
"start_date": "2017-02-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03096418",
"publication_url": "https://clinicaltrials.gov/study/NCT03096418",
"title": "Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response",
"has_exemption": false,
"start_date": "2017-03-13",
"completion_date": "2027-06-30",
"has_results": true,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "reported",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03067181",
"publication_url": "https://clinicaltrials.gov/study/NCT03067181",
"title": "A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors",
"has_exemption": false,
"start_date": "2017-05-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03179930",
"publication_url": "https://clinicaltrials.gov/study/NCT03179930",
"title": "A Phase II Study of Pembrolizumab and Entinostat in Patients With Relapsed and Refractory Lymphomas",
"has_exemption": false,
"start_date": "2017-06-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03204123",
"publication_url": "https://clinicaltrials.gov/study/NCT03204123",
"title": "PSMA PET Imaging of Recurrent Prostate Cancer",
"has_exemption": false,
"start_date": "2017-06-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03265431",
"publication_url": "https://clinicaltrials.gov/study/NCT03265431",
"title": "Evaluation of PET/MR in Patients Selected for Ablation Therapy",
"has_exemption": false,
"start_date": "2017-07-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03128034",
"publication_url": "https://clinicaltrials.gov/study/NCT03128034",
"title": "A Study Evaluating Escalating Doses of 211^At-Labeled Anti-CD45 MAb BC8-B10 (211^At-BC8-B10) Followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS)",
"has_exemption": true,
"start_date": "2017-10-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03726359",
"publication_url": "https://clinicaltrials.gov/study/NCT03726359",
"title": "Phase I TITE-CREM Dose Escalation Study of Fractionated Stereotactic Radiation Therapy (FSRT) in Unresected Brain Metastases",
"has_exemption": false,
"start_date": "2017-12-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Albert Einstein College of Medicine",
"sponsor_slug": "albert-einstein-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03281889",
"publication_url": "https://clinicaltrials.gov/study/NCT03281889",
"title": "Craniospinal Irradiation Using Proton Beam Scanning With Selective Vertebral Body/Bone Sparing to Improve Marrow Reserve and Decrease Growth Decrement for Children",
"has_exemption": false,
"start_date": "2018-01-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03392246",
"publication_url": "https://clinicaltrials.gov/study/NCT03392246",
"title": "A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer",
"has_exemption": false,
"start_date": "2018-01-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03191149",
"publication_url": "https://clinicaltrials.gov/study/NCT03191149",
"title": "Phase II Study of Osimertinib (AZD9291) in Advanced NSCLC Patients With Exon 20 Insertion Mutations in EGFR",
"has_exemption": false,
"start_date": "2018-04-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03457675",
"publication_url": "https://clinicaltrials.gov/study/NCT03457675",
"title": "Development of Adaptive Deep Brain Stimulation (aDBS) for the Treatment of Intractable OCD: Phase Ia Using Activa PC+S",
"has_exemption": false,
"start_date": "2018-07-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Baylor College of Medicine",
"sponsor_slug": "baylor-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03237780",
"publication_url": "https://clinicaltrials.gov/study/NCT03237780",
"title": "A Randomized, Phase 2 Trial to Evaluate the Safety and Efficacy of Eribulin Mesylate in Combination With Atezolizumab Compared to Atezolizumab Alone in Subjects With Locally Advanced or Metastatic Transitional Cell Urothelial Cancer Where Cisplatin-Based Treatment is Not an Option",
"has_exemption": false,
"start_date": "2018-07-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03530852",
"publication_url": "https://clinicaltrials.gov/study/NCT03530852",
"title": "A 90 Day, Phase 3, Open Labeled Exploratory Study of RELiZORB to Evaluate Safety, Tolerability, and Nutrient Absorption in Children With Short Bowel Syndrome Who Are Dependent on Parenteral Nutrition",
"has_exemption": false,
"start_date": "2018-11-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03550391",
"publication_url": "https://clinicaltrials.gov/study/NCT03550391",
"title": "A Phase III Trial of Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases",
"has_exemption": false,
"start_date": "2018-11-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03739502",
"publication_url": "https://clinicaltrials.gov/study/NCT03739502",
"title": "A Randomized Phase II Study Evaluating the Efficacy of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2019-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03883412",
"publication_url": "https://clinicaltrials.gov/study/NCT03883412",
"title": "Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)",
"has_exemption": false,
"start_date": "2019-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03728673",
"publication_url": "https://clinicaltrials.gov/study/NCT03728673",
"title": "A Pilot Study Utilizing Escitalopram to Address Cognitive Dysfunction in Glioma Patients",
"has_exemption": false,
"start_date": "2019-03-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03913026",
"publication_url": "https://clinicaltrials.gov/study/NCT03913026",
"title": "A Phase II Open-label Study of ECT-001-expanded Cord Blood Transplantation in Patients With High-risk Acute Leukemia/Myelodysplasia",
"has_exemption": false,
"start_date": "2019-04-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ciusss de L'Est de l'Île de Montréal",
"sponsor_slug": "ciusss-de-lest-de-lile-de-montreal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03970720",
"publication_url": "https://clinicaltrials.gov/study/NCT03970720",
"title": "Restoration of Hypoglycemia Awareness With Metoclopramide",
"has_exemption": false,
"start_date": "2019-05-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Simon Fisher",
"sponsor_slug": "simon-fisher",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03960840",
"publication_url": "https://clinicaltrials.gov/study/NCT03960840",
"title": "Phase I/II, Open Label, Multicenter Study of Rapcabtagene Autoleucel in Adult Patients With CLL/SLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL",
"has_exemption": false,
"start_date": "2019-06-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03897127",
"publication_url": "https://clinicaltrials.gov/study/NCT03897127",
"title": "Randomized Phase III Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics",
"has_exemption": false,
"start_date": "2019-09-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Ulm",
"sponsor_slug": "university-of-ulm",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03918252",
"publication_url": "https://clinicaltrials.gov/study/NCT03918252",
"title": "Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma",
"has_exemption": false,
"start_date": "2019-10-02",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03992378",
"publication_url": "https://clinicaltrials.gov/study/NCT03992378",
"title": "Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis",
"has_exemption": false,
"start_date": "2019-10-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04281134",
"publication_url": "https://clinicaltrials.gov/study/NCT04281134",
"title": "Development of Adaptive Deep Brain Stimulation (aDBS) for the Treatment of Intractable OCD: Phase Ib Using Summit RC+S",
"has_exemption": false,
"start_date": "2019-10-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Baylor College of Medicine",
"sponsor_slug": "baylor-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04050280",
"publication_url": "https://clinicaltrials.gov/study/NCT04050280",
"title": "A Phase II Study of Cladribine, Cytarabine, and Granulocyte-Colony Stimulating Factor With Fractionated Gemtuzumab Ozogamicin (CLAG-GO) for the Treatment of Patients With Persistent, Relapsed or Refractory Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2019-11-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04140500",
"publication_url": "https://clinicaltrials.gov/study/NCT04140500",
"title": "An Open Label, Multicenter, Dose Escalation, Phase 1 Study to Evaluate Safety/Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti Tumor Activity of RO7247669, a PD1-LAG3 Bispecific Antibody, in Patients With Advanced and/or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2019-11-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03546686",
"publication_url": "https://clinicaltrials.gov/study/NCT03546686",
"title": "A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer.",
"has_exemption": false,
"start_date": "2019-11-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03854474",
"publication_url": "https://clinicaltrials.gov/study/NCT03854474",
"title": "A Pilot Study of Tazemetostat and Pembrolizumab (MK-3475) in Advanced Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2019-11-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03969329",
"publication_url": "https://clinicaltrials.gov/study/NCT03969329",
"title": "Phase 3, Single-arm, Open-label, Multidose, Titration, Pharmacokinetic, Pharmacodynamic, and Safety Study of Etelcalcetide in Children and Adolescents ≥ 2 to < 18 Years of Age With Secondary Hyperparathyroidism and Chronic Kidney Disease Receiving Maintenance Hemodialysis",
"has_exemption": false,
"start_date": "2019-12-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04356469",
"publication_url": "https://clinicaltrials.gov/study/NCT04356469",
"title": "Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Non-Malignant Hematological Disorders in Children",
"has_exemption": false,
"start_date": "2020-07-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins All Children's Hospital",
"sponsor_slug": "johns-hopkins-all-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04414046",
"publication_url": "https://clinicaltrials.gov/study/NCT04414046",
"title": "Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children",
"has_exemption": false,
"start_date": "2020-07-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins All Children's Hospital",
"sponsor_slug": "johns-hopkins-all-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04090398",
"publication_url": "https://clinicaltrials.gov/study/NCT04090398",
"title": "Phase II Trial of Radium-223 Dichloride in Combination With Paclitaxel in Patients With Bone Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2020-08-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04189757",
"publication_url": "https://clinicaltrials.gov/study/NCT04189757",
"title": "A Phase II Study of Acalabrutinib in Ibrutinib-Intolerant Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2020-08-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04505254",
"publication_url": "https://clinicaltrials.gov/study/NCT04505254",
"title": "Intermittent Therapy With the BTK Inhibitor Acalabrutinib (Calquence) in Combination With Obinutuzumab in Treatment Naive (Tn) Patients With Chronic Lymphocytic Leukemia (CLL)",
"has_exemption": false,
"start_date": "2020-08-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04550260",
"publication_url": "https://clinicaltrials.gov/study/NCT04550260",
"title": "A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN)",
"has_exemption": false,
"start_date": "2020-10-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04668300",
"publication_url": "https://clinicaltrials.gov/study/NCT04668300",
"title": "A Phase II Multi-Arm Study to Test the Efficacy of Oleclumab and Durvalumab in Multiple Sarcoma Subtypes",
"has_exemption": false,
"start_date": "2020-11-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04666636",
"publication_url": "https://clinicaltrials.gov/study/NCT04666636",
"title": "Mechanisms for Activation of Beige Adipose Tissue in Humans",
"has_exemption": false,
"start_date": "2020-12-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Philip Kern",
"sponsor_slug": "philip-kern",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04511013",
"publication_url": "https://clinicaltrials.gov/study/NCT04511013",
"title": "A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases",
"has_exemption": false,
"start_date": "2021-01-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04634552",
"publication_url": "https://clinicaltrials.gov/study/NCT04634552",
"title": "A Phase 1/2, First-in-Human, Open-Label, Dose Escalation Study of Talquetamab, a Humanized GPRC5D x CD3 Bispecific Antibody, in Subjects With Relapsed or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2021-02-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04263831",
"publication_url": "https://clinicaltrials.gov/study/NCT04263831",
"title": "Low Dose IL-2 for the Treatment of Crohn's Disease",
"has_exemption": false,
"start_date": "2021-03-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04634916",
"publication_url": "https://clinicaltrials.gov/study/NCT04634916",
"title": "A Prospective, Multi-Center Clinical Study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis",
"has_exemption": false,
"start_date": "2021-03-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "C. R. Bard",
"sponsor_slug": "c-r-bard",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04786262",
"publication_url": "https://clinicaltrials.gov/study/NCT04786262",
"title": "A Phase 1/2/3 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus With Impaired Hypoglycemic Awareness and Severe Hypoglycemia",
"has_exemption": false,
"start_date": "2021-03-29",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04885322",
"publication_url": "https://clinicaltrials.gov/study/NCT04885322",
"title": "Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands",
"has_exemption": false,
"start_date": "2021-04-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04085406",
"publication_url": "https://clinicaltrials.gov/study/NCT04085406",
"title": "Deep Brain Stimulation of the Subgenual Cingulate Cortex for the Treatment of Medically Refractory Chronic Low Back Pain",
"has_exemption": false,
"start_date": "2021-05-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04416451",
"publication_url": "https://clinicaltrials.gov/study/NCT04416451",
"title": "A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma",
"has_exemption": false,
"start_date": "2021-05-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04855695",
"publication_url": "https://clinicaltrials.gov/study/NCT04855695",
"title": "A Phase 1/2 Study of Acalabrutinib, Venetoclax, and Obinutuzumab in Patients With Relapsed/Refractory and Previously Untreated Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2021-07-02",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Austin I Kim",
"sponsor_slug": "austin-i-kim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04554914",
"publication_url": "https://clinicaltrials.gov/study/NCT04554914",
"title": "An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety of Tabelecleucel in Subjects With Epstein Barr Virus Associated Diseases (EBVision)",
"has_exemption": false,
"start_date": "2021-07-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pierre Fabre Medicament",
"sponsor_slug": "pierre-fabre-medicament",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04731272",
"publication_url": "https://clinicaltrials.gov/study/NCT04731272",
"title": "Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults With Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a Randomized, Open-label, Cross-over Trial",
"has_exemption": false,
"start_date": "2021-07-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04911816",
"publication_url": "https://clinicaltrials.gov/study/NCT04911816",
"title": "Phase I/II Study of Neoadjuvant mFOLFIRINOX in Combination With Peri-operative Oral Hydroxychloroquine (FHQ) in Subjects With Resectable Adenocarcinoma of the Pancreas.",
"has_exemption": false,
"start_date": "2021-07-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "West Virginia University",
"sponsor_slug": "west-virginia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05112432",
"publication_url": "https://clinicaltrials.gov/study/NCT05112432",
"title": "EPI-MINN: Targeting Cognition and Motivation in Coordinated Specialty Care for Early Psychosis",
"has_exemption": false,
"start_date": "2021-08-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05095207",
"publication_url": "https://clinicaltrials.gov/study/NCT05095207",
"title": "A Multicenter, Phase IB/II Study of Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2021-09-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04831320",
"publication_url": "https://clinicaltrials.gov/study/NCT04831320",
"title": "Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor: A Single-Arm, Phase 2 Trial",
"has_exemption": false,
"start_date": "2021-09-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03324529",
"publication_url": "https://clinicaltrials.gov/study/NCT03324529",
"title": "Autonomic Modulation in Takotsubo Syndrome",
"has_exemption": false,
"start_date": "2021-10-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04713982",
"publication_url": "https://clinicaltrials.gov/study/NCT04713982",
"title": "Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease",
"has_exemption": false,
"start_date": "2021-11-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04988074",
"publication_url": "https://clinicaltrials.gov/study/NCT04988074",
"title": "A Phase II Trial of Cemiplimab, or Cemiplimab-Chemotherapy, Followed by Biomarker-guided De-escalated Curative-intent Locoregional Treatment for Patients With Advanced HPV-related Head and Neck Cancer. The MINIMA Study",
"has_exemption": false,
"start_date": "2021-12-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05148156",
"publication_url": "https://clinicaltrials.gov/study/NCT05148156",
"title": "Reduction of Urinary Toxicity of Stereotactic Body Radiation Therapy (SBRT) With Prostatic Urethral Lift (Urolift)",
"has_exemption": false,
"start_date": "2021-12-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04919226",
"publication_url": "https://clinicaltrials.gov/study/NCT04919226",
"title": "A Prospective, Randomised, Controlled, Open-label, Multicentre Study to Evaluate Efficacy, Safety and Patient-Reported Outcomes of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-Edotreotide Compared to Best Standard of Care in Patients With Well-differentiated Aggressive Grade 2 and Grade 3, Somatostatin Receptor-Positive (SSTR+), Neuroendocrine Tumours of GastroEnteric or Pancreatic Origin",
"has_exemption": false,
"start_date": "2021-12-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ITM Solucin GmbH",
"sponsor_slug": "itm-solucin-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05386277",
"publication_url": "https://clinicaltrials.gov/study/NCT05386277",
"title": "A Post Market Clinical Study to Confirm the Performance and Safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter on Patients Undergoing Surgical Treatment for the Removal of Arterial Emboli and/or Thrombi",
"has_exemption": false,
"start_date": "2022-01-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "LeMaitre Vascular",
"sponsor_slug": "lemaitre-vascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05185843",
"publication_url": "https://clinicaltrials.gov/study/NCT05185843",
"title": "An Open-Label Safety Study of AKCEA-APOCIII-LRX Administered Subcutaneously to Patients With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen (ISIS 304801)",
"has_exemption": false,
"start_date": "2022-02-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04988555",
"publication_url": "https://clinicaltrials.gov/study/NCT04988555",
"title": "A Phase 1/2, Open-Label, Dose-Escalation, Dose-Expansion Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia and Other Selected Hematologic Malignancies, With and Without Mixed Lineage Leukemia (MLL) Rearrangement or Nucleophosmin 1 (NPM1) Mutation (Horizen-1)",
"has_exemption": false,
"start_date": "2022-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sumitomo Pharma America, Inc.",
"sponsor_slug": "sumitomo-pharma-america-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05096663",
"publication_url": "https://clinicaltrials.gov/study/NCT05096663",
"title": "A Phase II/III Study of N-803 (ALT-803) Plus Pembrolizumab Versus Standard of Care in Participants With Stage IV or Recurrent Non-Small Cell Lung Cancer Previously Treated With Anti-PD-1 or Anti-PD-L1 Therapy (Lung-MAP Non-Match Sub-Study)",
"has_exemption": false,
"start_date": "2022-03-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05248230",
"publication_url": "https://clinicaltrials.gov/study/NCT05248230",
"title": "An Open-label, Phase 1/2 Trial of Gene Therapy 4D-710 in Adults With Cystic Fibrosis",
"has_exemption": false,
"start_date": "2022-03-29",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "4D Molecular Therapeutics",
"sponsor_slug": "4d-molecular-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05591547",
"publication_url": "https://clinicaltrials.gov/study/NCT05591547",
"title": "SH APBI RISE: Evaluating the Safety and Efficacy of a Novel IMRT/VMAT-based Accelerated Partial Breast Irradiation Regimen for patIents With Favorable Risk breaSt cancEr",
"has_exemption": false,
"start_date": "2022-03-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanford Health",
"sponsor_slug": "sanford-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05292794",
"publication_url": "https://clinicaltrials.gov/study/NCT05292794",
"title": "A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed With Parkinson's Disease",
"has_exemption": false,
"start_date": "2022-04-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "CereGate Inc.",
"sponsor_slug": "ceregate-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05275686",
"publication_url": "https://clinicaltrials.gov/study/NCT05275686",
"title": "Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD) in a Multi-center, Double-Blinded, Placebo-controlled Trial",
"has_exemption": false,
"start_date": "2022-04-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05444452",
"publication_url": "https://clinicaltrials.gov/study/NCT05444452",
"title": "Comparison Between Abluminal Biodegradable Polymer Ultrathin Sirolimus-eluting Stent and Durable-polymer Everolimus-eluting Stent (GENOSS Randomized Clinical Trial)",
"has_exemption": false,
"start_date": "2022-04-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Samsung Medical Center",
"sponsor_slug": "samsung-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05416307",
"publication_url": "https://clinicaltrials.gov/study/NCT05416307",
"title": "A Multipart, Open-label, Single-arm, Multicenter Study to Evaluate the Safety, Efficacy and Pharmacokinetics of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Electra Therapeutics Inc.",
"sponsor_slug": "electra-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05099003",
"publication_url": "https://clinicaltrials.gov/study/NCT05099003",
"title": "A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG)",
"has_exemption": false,
"start_date": "2022-05-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05239624",
"publication_url": "https://clinicaltrials.gov/study/NCT05239624",
"title": "Enfortumab Vedotin in Combination With Pembrolizumab for Locally Advanced and/or Node Positive Urothelial Carcinoma Prior to Surgery (EV-ECLIPSE)",
"has_exemption": false,
"start_date": "2022-06-02",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05417100",
"publication_url": "https://clinicaltrials.gov/study/NCT05417100",
"title": "Modulation of Post-operative Opioid Consumption and Pain by Intraoperative Methadone for Cancer Related Spinal Surgery - An Investigator Initiated Trial (IIT), Cluster Randomization Trial",
"has_exemption": false,
"start_date": "2022-06-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05388929",
"publication_url": "https://clinicaltrials.gov/study/NCT05388929",
"title": "Addition of Methocarbamol to Postoperative Multimodal Analgesic Regimen: A Prospective, Randomized Pilot Study",
"has_exemption": false,
"start_date": "2022-06-23",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Prisma Health-Upstate",
"sponsor_slug": "prisma-health-upstate",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05218850",
"publication_url": "https://clinicaltrials.gov/study/NCT05218850",
"title": "Butyrate Therapy in Hispanic Children With Ulcerative Colitis",
"has_exemption": false,
"start_date": "2022-06-29",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Los Angeles",
"sponsor_slug": "childrens-hospital-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05265273",
"publication_url": "https://clinicaltrials.gov/study/NCT05265273",
"title": "An Open-Label Uncontrolled Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Activity of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis",
"has_exemption": false,
"start_date": "2022-07-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05172258",
"publication_url": "https://clinicaltrials.gov/study/NCT05172258",
"title": "A Phase 2 Study of Ipatasertib in Combination With Pembrolizumab for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck",
"has_exemption": false,
"start_date": "2022-07-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285878",
"publication_url": "https://clinicaltrials.gov/study/NCT05285878",
"title": "A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation",
"has_exemption": false,
"start_date": "2022-07-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04646226",
"publication_url": "https://clinicaltrials.gov/study/NCT04646226",
"title": "A Randomized Trial of Fistula vs. Graft Arteriovenous Vascular Access in Older Adults With End-Stage Kidney Disease on Hemodialysis",
"has_exemption": false,
"start_date": "2022-08-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05430230",
"publication_url": "https://clinicaltrials.gov/study/NCT05430230",
"title": "N of 1 Pilot Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee Osteoarthritis",
"has_exemption": false,
"start_date": "2022-08-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05147103",
"publication_url": "https://clinicaltrials.gov/study/NCT05147103",
"title": "Investigation of the Duration of Low-intensity Focused Ultrasound",
"has_exemption": false,
"start_date": "2022-08-26",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Polytechnic Institute and State University",
"sponsor_slug": "virginia-polytechnic-institute-and-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05188183",
"publication_url": "https://clinicaltrials.gov/study/NCT05188183",
"title": "Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response",
"has_exemption": false,
"start_date": "2022-09-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Spaulding Rehabilitation Hospital",
"sponsor_slug": "spaulding-rehabilitation-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564091",
"publication_url": "https://clinicaltrials.gov/study/NCT05564091",
"title": "Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma",
"has_exemption": false,
"start_date": "2022-09-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nova Eye, Inc.",
"sponsor_slug": "nova-eye-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05543694",
"publication_url": "https://clinicaltrials.gov/study/NCT05543694",
"title": "ED90 of Epidural Bupivacaine for the Initiation of Labor Analgesia: A Randomized Biased Coin Sequential Allocation Trial With a Lidocaine Test Dose",
"has_exemption": false,
"start_date": "2022-10-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05381597",
"publication_url": "https://clinicaltrials.gov/study/NCT05381597",
"title": "Combination of 5-Fluorouracil and Calcipotriene in the Treatment of Superficial Basal Cell Carcinomas and Squamous Cell Carcinomas in Situ",
"has_exemption": false,
"start_date": "2022-10-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston University",
"sponsor_slug": "boston-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06128720",
"publication_url": "https://clinicaltrials.gov/study/NCT06128720",
"title": "A Randomized, Sham Controlled, Masked Phase II Study to Evaluate the Neuroprotective Effect of Hyperbaric Oxygen Therapy on Optic Neuropathy",
"has_exemption": false,
"start_date": "2022-11-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05518903",
"publication_url": "https://clinicaltrials.gov/study/NCT05518903",
"title": "Quantitative In Vivo 68Ga-Fibroblast-Activation-Protein-Inhibitors (FAPI)-46 PET Imaging of Cancer-Associated Fibroblasts (CAFs) in Pancreatic Ductal Adenocarcinoma (PDA)",
"has_exemption": false,
"start_date": "2022-11-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05641688",
"publication_url": "https://clinicaltrials.gov/study/NCT05641688",
"title": "An Open-label, Non-randomized, Multi-center Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of PET Imaging With [18F]PI-2620 for the Detection of Tau Deposition When Compared to Post-mortem Histopathology (ADvance)",
"has_exemption": false,
"start_date": "2022-12-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Lantheus Biosciences Ltd.",
"sponsor_slug": "lantheus-biosciences-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05633654",
"publication_url": "https://clinicaltrials.gov/study/NCT05633654",
"title": "A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy",
"has_exemption": false,
"start_date": "2022-12-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05198830",
"publication_url": "https://clinicaltrials.gov/study/NCT05198830",
"title": "A Phase 2 Randomized Study of the BER Inhibitor TRC102 in Combination With Standard Pemetrexed-Platinum-Radiation in Stage III Non-Squamous Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2022-12-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05499702",
"publication_url": "https://clinicaltrials.gov/study/NCT05499702",
"title": "The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction",
"has_exemption": false,
"start_date": "2022-12-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Adrian Vella",
"sponsor_slug": "adrian-vella",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05674825",
"publication_url": "https://clinicaltrials.gov/study/NCT05674825",
"title": "An Open-label, Navigational Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses",
"has_exemption": false,
"start_date": "2022-12-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05396105",
"publication_url": "https://clinicaltrials.gov/study/NCT05396105",
"title": "A Phase II/III, Extension Study of Orally Administered PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema",
"has_exemption": false,
"start_date": "2022-12-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharvaris Netherlands B.V.",
"sponsor_slug": "pharvaris-netherlands-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05442034",
"publication_url": "https://clinicaltrials.gov/study/NCT05442034",
"title": "Rh-PDGF Versus Emdogain for Treatment of Intra-bony Defects",
"has_exemption": false,
"start_date": "2023-01-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nova Southeastern University",
"sponsor_slug": "nova-southeastern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04216927",
"publication_url": "https://clinicaltrials.gov/study/NCT04216927",
"title": "Efficacy of Nitric Oxide Administration During Cardiopulmonary Bypass in Neonates at Reducing the Risk of Acute Kidney Injury",
"has_exemption": false,
"start_date": "2023-01-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05386342",
"publication_url": "https://clinicaltrials.gov/study/NCT05386342",
"title": "A Post-market Clinical Study to Confirm the Performance and Safety of the LeMaitre TufTex Over-the-Wire (OTW) Embolectomy Catheter on Patients Undergoing Surgical Treatment for the Removal of Arterial Emboli and/or Thrombi",
"has_exemption": false,
"start_date": "2023-01-11",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "LeMaitre Vascular",
"sponsor_slug": "lemaitre-vascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05086497",
"publication_url": "https://clinicaltrials.gov/study/NCT05086497",
"title": "Whole-Brain Spectroscopy Guided Personalized Mapping of Transducer Arrays for Glioblastoma Patients Receiving Tumor Treating Fields",
"has_exemption": false,
"start_date": "2023-01-15",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05586776",
"publication_url": "https://clinicaltrials.gov/study/NCT05586776",
"title": "Decolonization to Reduce After-Surgery Events of Surgical Site Infection",
"has_exemption": false,
"start_date": "2023-01-17",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05357612",
"publication_url": "https://clinicaltrials.gov/study/NCT05357612",
"title": "Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases",
"has_exemption": false,
"start_date": "2023-01-23",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05173324",
"publication_url": "https://clinicaltrials.gov/study/NCT05173324",
"title": "Integration of HPV Vaccination and HPV-based Cervical Screening in Young Adult WLWH Into ARV Clinics to Speed the Pathway Towards Cervical Cancer Elimination: the H2VICTORY Trial",
"has_exemption": false,
"start_date": "2023-02-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "International Agency for Research on Cancer",
"sponsor_slug": "international-agency-for-research-on-cancer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05578976",
"publication_url": "https://clinicaltrials.gov/study/NCT05578976",
"title": "A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)",
"has_exemption": false,
"start_date": "2023-02-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05739981",
"publication_url": "https://clinicaltrials.gov/study/NCT05739981",
"title": "Phase II Study Evaluating the Effect of IMNN-001 on Second Look Laparoscopy (SLL) in Combination With Bevacizumab (BEV) and Neoadjuvant Chemotherapy (NACT) in Newly Diagnosed With Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer",
"has_exemption": false,
"start_date": "2023-02-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Imunon",
"sponsor_slug": "imunon",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05566795",
"publication_url": "https://clinicaltrials.gov/study/NCT05566795",
"title": "LOGGIC/FIREFLY-2: A Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients With Pediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy",
"has_exemption": false,
"start_date": "2023-02-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Day One Biopharmaceuticals, Inc.",
"sponsor_slug": "day-one-biopharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05651022",
"publication_url": "https://clinicaltrials.gov/study/NCT05651022",
"title": "A Phase 1/2, Open-Label, Multi-Center, Dose Escalation and Expansion Study Evaluating the Safety, Tolerability and Clinical Activity of DECOY20 as Monotherapy and in Combination With Tislelizumab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-02-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indaptus Therapeutics, Inc",
"sponsor_slug": "indaptus-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05507138",
"publication_url": "https://clinicaltrials.gov/study/NCT05507138",
"title": "Efficacy and Target Engagement of a Digital Intervention to Improve Depression and Executive Dysfunction After Stroke",
"has_exemption": false,
"start_date": "2023-03-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05570812",
"publication_url": "https://clinicaltrials.gov/study/NCT05570812",
"title": "In Vivo Targeting of Neuroactive Steroid and Immune Networks for Depression in People Living With HIV",
"has_exemption": false,
"start_date": "2023-03-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04685317",
"publication_url": "https://clinicaltrials.gov/study/NCT04685317",
"title": "A Pilot Randomized Study of the Use of The Sentinel Device for Cerebral Protection During Atrial Fibrillation Ablation",
"has_exemption": false,
"start_date": "2023-03-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Malini Madhavan",
"sponsor_slug": "malini-madhavan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05706129",
"publication_url": "https://clinicaltrials.gov/study/NCT05706129",
"title": "A Multicenter, Open-Label, Non-Randomized Phase 1/2 Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Patients With Unresectable Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2023-03-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Lumara Bio Oncologics GmbH",
"sponsor_slug": "lumara-bio-oncologics-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05432804",
"publication_url": "https://clinicaltrials.gov/study/NCT05432804",
"title": "A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2023-03-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03862430",
"publication_url": "https://clinicaltrials.gov/study/NCT03862430",
"title": "A Phase II Double-blind, RandomizEd, Prospective, Placebo Controlled STudy of NanO2TM Combined With Radiation and Temozolomide in Patients With Newly-diagnosed Glioblastoma multiformE: RESTORE",
"has_exemption": false,
"start_date": "2023-03-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NuvOx LLC",
"sponsor_slug": "nuvox-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05752071",
"publication_url": "https://clinicaltrials.gov/study/NCT05752071",
"title": "GaStrointestinal STIMULation As a Treatment of Postoperative IlEus Following Extensive Surgery (STIMULATE). -A Prospective Double-blinded Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2023-04-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Aarhus",
"sponsor_slug": "university-of-aarhus",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05759988",
"publication_url": "https://clinicaltrials.gov/study/NCT05759988",
"title": "Cervical Ripening as an Outpatient Method Using the Foley: a Randomized Trial",
"has_exemption": false,
"start_date": "2023-04-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05918835",
"publication_url": "https://clinicaltrials.gov/study/NCT05918835",
"title": "Deciphering the Neural Mechanisms of Restrictive Eating in Anorexia Nervosa Using Repetitive Transcranial Magnetic Stimulation",
"has_exemption": false,
"start_date": "2023-04-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "New York State Psychiatric Institute",
"sponsor_slug": "new-york-state-psychiatric-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05537935",
"publication_url": "https://clinicaltrials.gov/study/NCT05537935",
"title": "Low Dose Naltrexone (LDN) for the Treatment of Chronic Neuropathic Pain in Patients With Human Immunodeficiency Virus (HIV), a Prospective, Pragmatic, Open Label Clinical Trial",
"has_exemption": false,
"start_date": "2023-04-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05483465",
"publication_url": "https://clinicaltrials.gov/study/NCT05483465",
"title": "Effects of NAD Restoration on Neurovascular Coupling in Community Dwelling Older Adults",
"has_exemption": false,
"start_date": "2023-05-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05642572",
"publication_url": "https://clinicaltrials.gov/study/NCT05642572",
"title": "A Randomized Phase II Study of INC280 (Capmatinib) Plus Osimertinib With or Without Ramucirumab in Participants With EGFR-Mutant, MET-Amplified Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)",
"has_exemption": false,
"start_date": "2023-05-05",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05362032",
"publication_url": "https://clinicaltrials.gov/study/NCT05362032",
"title": "Feasibility of OmnEcoil System for Integrated Endorectal MRI and Transrectal MRI-Targeted Biopsy of the Prostate",
"has_exemption": false,
"start_date": "2023-05-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "OHSU Knight Cancer Institute",
"sponsor_slug": "ohsu-knight-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05289687",
"publication_url": "https://clinicaltrials.gov/study/NCT05289687",
"title": "A Phase II Study of Daratumumab-Hyaluronidase for Chemotherapy-Relapsed/Refractory Minimal Residual Disease (MRD) in T Cell Acute Lymphoblastic Leukemia (T-ALL",
"has_exemption": false,
"start_date": "2023-05-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eastern Cooperative Oncology Group",
"sponsor_slug": "eastern-cooperative-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05864144",
"publication_url": "https://clinicaltrials.gov/study/NCT05864144",
"title": "A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SNS-101 (Anti VISTA) as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sensei Biotherapeutics, Inc.",
"sponsor_slug": "sensei-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05919797",
"publication_url": "https://clinicaltrials.gov/study/NCT05919797",
"title": "Association of Genetic Variations and Weight Loss Response to Naltrexone/Bupropion",
"has_exemption": false,
"start_date": "2023-06-08",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05884125",
"publication_url": "https://clinicaltrials.gov/study/NCT05884125",
"title": "Promoting Healing of Injured Nerves With Electrical Stimulation Therapy",
"has_exemption": false,
"start_date": "2023-06-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Checkpoint Surgical Inc.",
"sponsor_slug": "checkpoint-surgical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05926765",
"publication_url": "https://clinicaltrials.gov/study/NCT05926765",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia",
"has_exemption": false,
"start_date": "2023-06-13",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "MeiraGTx, LLC",
"sponsor_slug": "meiragtx-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05742607",
"publication_url": "https://clinicaltrials.gov/study/NCT05742607",
"title": "Official Title: A Phase II Multicenter, Open Label, Non-randomized Study of Neoadjuvant and Adjuvant Treatment With IPH5201 and Durvalumab in Patients With Resectable, Early-Stage (II to III) Non-Small Cell Lung CancEr (MATISSE)",
"has_exemption": false,
"start_date": "2023-06-23",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Innate Pharma",
"sponsor_slug": "innate-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05878769",
"publication_url": "https://clinicaltrials.gov/study/NCT05878769",
"title": "A Phase III Open-Label Extension Study to Evaluate the Long-Term Safety of Astegolimab in Patients With Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2023-06-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05839652",
"publication_url": "https://clinicaltrials.gov/study/NCT05839652",
"title": "Treatment of Orthostatic Hypotension in Individuals With Spinal Cord Injury",
"has_exemption": false,
"start_date": "2023-07-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "James J. Peters Veterans Affairs Medical Center",
"sponsor_slug": "james-j-peters-veterans-affairs-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05994014",
"publication_url": "https://clinicaltrials.gov/study/NCT05994014",
"title": "PET/CT vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease",
"has_exemption": false,
"start_date": "2023-07-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05552755",
"publication_url": "https://clinicaltrials.gov/study/NCT05552755",
"title": "A Phase 1b-2, Multicenter, Trial to Evaluate the Efficacy, Safety, Pharmacokintetics, and Pharmacodynamics of REC-4881 in Patients With Familial Adenomatous Polyposis (FAP)",
"has_exemption": false,
"start_date": "2023-07-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Recursion Pharmaceuticals Inc.",
"sponsor_slug": "recursion-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05929937",
"publication_url": "https://clinicaltrials.gov/study/NCT05929937",
"title": "No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair",
"has_exemption": false,
"start_date": "2023-07-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Clayton Petro",
"sponsor_slug": "clayton-petro",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05554341",
"publication_url": "https://clinicaltrials.gov/study/NCT05554341",
"title": "Nilotinib and Paclitaxel in Patients With Prior Taxane-Treated Solid Tumors: A ComboMATCH Treatment Trial",
"has_exemption": false,
"start_date": "2023-07-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05949593",
"publication_url": "https://clinicaltrials.gov/study/NCT05949593",
"title": "PHase 3, Multicenter, RandOmized, Double-masked, PlacEbo-CoNtrolled Study of TInlarebant to EXplore Safety and Efficacy in the Treatment of Geographic Atrophy (the PHOENIX Study)",
"has_exemption": false,
"start_date": "2023-07-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Belite Bio, Inc",
"sponsor_slug": "belite-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05825066",
"publication_url": "https://clinicaltrials.gov/study/NCT05825066",
"title": "Sequential Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma",
"has_exemption": false,
"start_date": "2023-08-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05908084",
"publication_url": "https://clinicaltrials.gov/study/NCT05908084",
"title": "A Phase 3 Randomized Study to Compare the Efficacy and Safety of the Humacyte Acellular Tissue Engineered Vessel (ATEV) With That of an Autogenous Arteriovenous Fistula (AVF) in Female Patients With End-Stage Renal Disease Requiring Hemodialysis",
"has_exemption": false,
"start_date": "2023-09-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Humacyte, Inc.",
"sponsor_slug": "humacyte-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05682677",
"publication_url": "https://clinicaltrials.gov/study/NCT05682677",
"title": "Combined Neuromodulation and Cognitive Training for Post-mTBI Depression",
"has_exemption": false,
"start_date": "2023-09-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06075537",
"publication_url": "https://clinicaltrials.gov/study/NCT06075537",
"title": "An Open-Label Extension to Investigate the Long-Term Safety, Tolerability, and Efficacy of DNL310 in Patients With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007",
"has_exemption": false,
"start_date": "2023-09-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05679674",
"publication_url": "https://clinicaltrials.gov/study/NCT05679674",
"title": "Phase 2 Trial of Ablative MRI-guided Stereotactic Body Radiation Therapy and Tumor Treating Fields for Locally Advanced Pancreas Cancer",
"has_exemption": false,
"start_date": "2023-09-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Baptist Health South Florida",
"sponsor_slug": "baptist-health-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07103733",
"publication_url": "https://clinicaltrials.gov/study/NCT07103733",
"title": "Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY) Ancillary Substudy",
"has_exemption": false,
"start_date": "2023-10-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Annetine Gelijns",
"sponsor_slug": "annetine-gelijns",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05946629",
"publication_url": "https://clinicaltrials.gov/study/NCT05946629",
"title": "A Prospective Randomized Single-Blind Multicenter Study to Assess the Safety and Effectiveness of the SELUTION SLR™ 014 PTCA Drug Eluting Balloon in the Treatment of Subjects With De Novo Coronary Lesions in Small Vessels",
"has_exemption": false,
"start_date": "2023-10-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.A. Med Alliance S.A.",
"sponsor_slug": "ma-med-alliance-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05980000",
"publication_url": "https://clinicaltrials.gov/study/NCT05980000",
"title": "Open-Label, Randomized Phase 2 Trial of Ramucirumab in Combination With Pembrolizumab Versus Pembrolizumab Alone as First-Line Treatment of PD-L1 Positive, Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma (RM-HNSCC)",
"has_exemption": false,
"start_date": "2023-10-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05063565",
"publication_url": "https://clinicaltrials.gov/study/NCT05063565",
"title": "An Open-Label, Prospective, Multi-Center Clinical Trial to Evaluate the Efficacy and Safety of TheraSphere™ Followed by Durvalumab (Imfinzi®) With Tremelimumab (Imjudo®) for Hepatocellular Carcinoma (HCC)",
"has_exemption": false,
"start_date": "2023-11-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Scientific Corporation",
"sponsor_slug": "boston-scientific-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06029439",
"publication_url": "https://clinicaltrials.gov/study/NCT06029439",
"title": "Long-term Study to Assess the Safety and Effectiveness of NMRA-335140 in Participants With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2023-11-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Neumora Therapeutics, Inc.",
"sponsor_slug": "neumora-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05920356",
"publication_url": "https://clinicaltrials.gov/study/NCT05920356",
"title": "A Phase 3, Multicenter, Randomized, Open-label Study Evaluating Efficacy of Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Subjects With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers, Negative for PD-L1, and Positive for KRAS p.G12C (CodeBreaK 202)",
"has_exemption": false,
"start_date": "2023-11-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06146842",
"publication_url": "https://clinicaltrials.gov/study/NCT06146842",
"title": "A Trial to Determine the Optimal Bupivacaine Dose for Initiation of Labor Epidural Pain Relief With a Lidocaine Test Dose",
"has_exemption": false,
"start_date": "2023-12-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05459636",
"publication_url": "https://clinicaltrials.gov/study/NCT05459636",
"title": "Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults With Obesity",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Florida State University",
"sponsor_slug": "florida-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05905328",
"publication_url": "https://clinicaltrials.gov/study/NCT05905328",
"title": "Phase 1B/2A Study of CTO1681 for the Prevention and Treatment of Cytokine Release Syndrome in Patients With Diffuse Large B-Cell Lymphoma Receiving Chimeric Antigen Receptor T-Cell Therapy",
"has_exemption": false,
"start_date": "2023-12-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "CytoAgents, Inc.",
"sponsor_slug": "cytoagents-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06001827",
"publication_url": "https://clinicaltrials.gov/study/NCT06001827",
"title": "SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study",
"has_exemption": false,
"start_date": "2024-01-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VenoStent",
"sponsor_slug": "venostent",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06159335",
"publication_url": "https://clinicaltrials.gov/study/NCT06159335",
"title": "Use of 18F-Fluciclovine PET for Discerning Tumor From Treatment Change in Patients With Brain Metastases Undergoing Immunotherapy",
"has_exemption": false,
"start_date": "2024-01-10",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06162221",
"publication_url": "https://clinicaltrials.gov/study/NCT06162221",
"title": "A Platform Study of RAS(ON) Inhibitors in Patients With RAS-Mutated Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2024-01-18",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Revolution Medicines, Inc.",
"sponsor_slug": "revolution-medicines-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06015724",
"publication_url": "https://clinicaltrials.gov/study/NCT06015724",
"title": "A Phase 2 Study Evaluating the Efficacy of Anti-CD38 Antibody in Combination With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Georgetown University",
"sponsor_slug": "georgetown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04941599",
"publication_url": "https://clinicaltrials.gov/study/NCT04941599",
"title": "2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)",
"has_exemption": false,
"start_date": "2024-02-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06234202",
"publication_url": "https://clinicaltrials.gov/study/NCT06234202",
"title": "The Effect of a Bioactive Fabric Sleeve on Recovery in Division I Collegiate Baseball Players",
"has_exemption": false,
"start_date": "2024-02-16",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06385236",
"publication_url": "https://clinicaltrials.gov/study/NCT06385236",
"title": "Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping",
"has_exemption": false,
"start_date": "2024-02-19",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06035120",
"publication_url": "https://clinicaltrials.gov/study/NCT06035120",
"title": "An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema: The CONVERT II Trial",
"has_exemption": false,
"start_date": "2024-02-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pulmonx Corporation",
"sponsor_slug": "pulmonx-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06075745",
"publication_url": "https://clinicaltrials.gov/study/NCT06075745",
"title": "Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates (CTOT-44)",
"has_exemption": false,
"start_date": "2024-03-05",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06108063",
"publication_url": "https://clinicaltrials.gov/study/NCT06108063",
"title": "Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan",
"has_exemption": false,
"start_date": "2024-03-06",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Steadman Philippon Research Institute",
"sponsor_slug": "steadman-philippon-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06297226",
"publication_url": "https://clinicaltrials.gov/study/NCT06297226",
"title": "A Phase 2, Open-Label, Multicenter Study of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)",
"has_exemption": false,
"start_date": "2024-03-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Juno Therapeutics, Inc., a Bristol-Myers Squibb Company",
"sponsor_slug": "juno-therapeutics-inc-a-bristol-myers-squibb-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05460468",
"publication_url": "https://clinicaltrials.gov/study/NCT05460468",
"title": "Adaptive Neuromodulation of Working Memory Networks in Aging and Dementia",
"has_exemption": false,
"start_date": "2024-03-28",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06329401",
"publication_url": "https://clinicaltrials.gov/study/NCT06329401",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study Evaluating the Safety and Efficacy of Pirfenidone Solution for Inhalation (AP01) in Participants With PPF",
"has_exemption": false,
"start_date": "2024-04-03",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Avalyn Pharma Inc.",
"sponsor_slug": "avalyn-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05822609",
"publication_url": "https://clinicaltrials.gov/study/NCT05822609",
"title": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes",
"has_exemption": false,
"start_date": "2024-04-05",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05980806",
"publication_url": "https://clinicaltrials.gov/study/NCT05980806",
"title": "A Phase 2 Study to Evaluate the Efficacy and Safety of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia",
"has_exemption": false,
"start_date": "2024-04-22",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Karyopharm Therapeutics Inc",
"sponsor_slug": "karyopharm-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06110572",
"publication_url": "https://clinicaltrials.gov/study/NCT06110572",
"title": "(TESSERACT): Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation (TBI)",
"has_exemption": false,
"start_date": "2024-04-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06361498",
"publication_url": "https://clinicaltrials.gov/study/NCT06361498",
"title": "Accuracy of Ultrasound for the Evaluation of Percutaneous Gastrostomy Tube Position and Leakage",
"has_exemption": false,
"start_date": "2024-04-30",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of North Carolina, Chapel Hill",
"sponsor_slug": "university-of-north-carolina-chapel-hill",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06087926",
"publication_url": "https://clinicaltrials.gov/study/NCT06087926",
"title": "Investigation of Non-invasive Brain Stimulation for the Treatment of Apathy",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of North Carolina, Chapel Hill",
"sponsor_slug": "university-of-north-carolina-chapel-hill",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06237452",
"publication_url": "https://clinicaltrials.gov/study/NCT06237452",
"title": "A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection",
"has_exemption": false,
"start_date": "2024-05-20",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vedanta Biosciences, Inc.",
"sponsor_slug": "vedanta-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06430268",
"publication_url": "https://clinicaltrials.gov/study/NCT06430268",
"title": "Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants: A Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2024-05-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Andrea Ravida",
"sponsor_slug": "andrea-ravida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05922761",
"publication_url": "https://clinicaltrials.gov/study/NCT05922761",
"title": "An Open-Label, Phase 2 Study to Evaluate the Activity of Belumosudil in Subjects With New Onset and Incipient Bronchiolitis Obliterans Syndrome Following Allogeneic Hematopoietic Cell Transplantation",
"has_exemption": false,
"start_date": "2024-05-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06457919",
"publication_url": "https://clinicaltrials.gov/study/NCT06457919",
"title": "A Phase 1b/2 Study Evaluating the Activity of Tinengotinib (TT-00420) in Combination With Androgen Receptor Signaling Inhibitors (ARSIs) in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2024-06-04",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06480240",
"publication_url": "https://clinicaltrials.gov/study/NCT06480240",
"title": "A Phase 1/2, Open-Label, Dose-Escalation and Cohort-Expansion Study Evaluating the Safety, Pharmacokinetics, and Therapeutic Activity of OBI-992 in Subjects With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2024-06-12",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "OBI Pharma, Inc",
"sponsor_slug": "obi-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06353269",
"publication_url": "https://clinicaltrials.gov/study/NCT06353269",
"title": "Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections",
"has_exemption": false,
"start_date": "2024-06-14",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05879835",
"publication_url": "https://clinicaltrials.gov/study/NCT05879835",
"title": "Safety and Effectiveness of 4% Tetrasodium Ethylenediaminetetraacetic Acid Catheter Lock Solution in Preventing Central Venous Catheter Occlusions in Children With Intestinal Failure: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-06-21",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SterileCare Inc.",
"sponsor_slug": "sterilecare-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06977451",
"publication_url": "https://clinicaltrials.gov/study/NCT06977451",
"title": "An Open-Label Single Center, Single Participant Study of an Experimental Antisense Oligonucleotide Treatment for Amyotrophic Lateral Sclerosis (ALS) Due to an Arg15Leu Pathogenic Variant in CHCHD10",
"has_exemption": false,
"start_date": "2024-06-24",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "n-Lorem Foundation",
"sponsor_slug": "n-lorem-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06424184",
"publication_url": "https://clinicaltrials.gov/study/NCT06424184",
"title": "Substance Use Disorder Treatment With Accelerated Repetitive Transcranial Magnetic Stimulation for Depression (START-D)",
"has_exemption": false,
"start_date": "2024-06-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06485778",
"publication_url": "https://clinicaltrials.gov/study/NCT06485778",
"title": "Phase 2 Single Arm Trial of Adjuvant Nodal Irradiation Alone in Post Operative Oral Tongue Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2024-06-27",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05705492",
"publication_url": "https://clinicaltrials.gov/study/NCT05705492",
"title": "ACTO: A Phase II, Randomized, Placebo-Controlled Study Evaluating Olanzapine in the Management of Cancer Cachexia",
"has_exemption": false,
"start_date": "2024-07-17",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "OHSU Knight Cancer Institute",
"sponsor_slug": "ohsu-knight-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06469801",
"publication_url": "https://clinicaltrials.gov/study/NCT06469801",
"title": "Low-Field Bedside MRI for Detection of Acute Brain Injury in Pediatric Extracorporeal Membrane Oxygenation",
"has_exemption": false,
"start_date": "2024-07-23",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Mercy Hospital Kansas City",
"sponsor_slug": "childrens-mercy-hospital-kansas-city",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06452589",
"publication_url": "https://clinicaltrials.gov/study/NCT06452589",
"title": "A Pre-Market, First-In-Human, Pilot, Interventional, Clinical Investigation to Evaluate Safety and Feasibility of the FieldForce™ Ablation System in Patients With Atrial Fibrillation",
"has_exemption": false,
"start_date": "2024-07-25",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Field Medical",
"sponsor_slug": "field-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06226805",
"publication_url": "https://clinicaltrials.gov/study/NCT06226805",
"title": "A Multicenter, Double-blinded, Placebo-controlled, Single Ascending Dose, Two-part, Randomized, Phase 2 Clinical Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BB-031 in Acute Ischemic Stroke Patients",
"has_exemption": false,
"start_date": "2024-07-31",
"completion_date": "2027-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Basking Biosciences, Inc.",
"sponsor_slug": "basking-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}