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"title": "A Phase 2 Open-label Study of Brentuximab Vedotin in Front-line Therapy of Hodgkin Lymphoma (HL) an dCD30-expressing Peripheral T-cell Lymphoma (PTCL) in Older Patients or Patients With Significant Comorbidities Ineligible for Standard Chemotherapy",
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"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SPI-1005 in Cystic Fibrosis (CF) Patients With Acute Pulmonary Exacerbation (APE) Receiving IV Tobramycin at Risk for Ototoxicity",
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"title": "STEEL: A Randomized Phase II Trial of Salvage Radiotherapy With Standard vs Enhanced Androgen Deprivation Therapy (With Enzalutamide) in Patients With Post-Prostatectomy PSA Recurrences With Aggressive Disease Features",
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"title": "Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty: A Prospective, Non-Randomized Multi-Center Post-market Clinical Investigation",
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"title": "AGAVE-201, A Phase 2, Open-label, Randomized, Multicenter Study to Evaluate the Efficacy, Safety and Tolerability of Axatilimab at 3 Different Doses in Patients With Recurrent or Refractory Active Chronic Graft Versus Host Disease Who Have Received at Least 2 Lines of Systemic Therapy",
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"title": "A Phase 2, Randomized, Open-Label Study of Trilaciclib Administered With First-Line Platinum-Based Chemotherapy and Avelumab Maintenance Therapy in Patients With Untreated, Locally Advanced or Metastatic Urothelial Carcinoma (PRESERVE 3)",
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"title": "IV vs. Erector Spinae Plane Blocks-Cardiac Surgery",
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"title": "A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.",
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"title": "Absorbable Versus Nonabsorbable Sutures for the Treatment of Knee Arthroscopy: A Prospective Comparison of Patient Outcomes and Satisfaction",
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"title": "APPLY Study: A Prospective, Single Center Study Appraising the Embolization of Aneurysms Using the Balt Optima™ Coil System",
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"title": "A Pilot Study To Evaluate Patient Experience With the Somatostatin Analogs Octreotide Long Acting Release and Lanreotide During the Treatment of Advanced, Nonfunctional, Well Differentiated Neuroendocrine Tumors",
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"title": "Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis BRAVOS: A Phase 1/2 Multicenter Randomized, Double Blinded, Safety Study (ITN075AI)",
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"title": "Prospective Analysis of STRATAFIX Symmetric PDS Plus Suture for Fascial Closure in Spinal Surgery; Pilot Study",
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"title": "Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida: An Open Label, Comparative Effectiveness, Randomized Controlled Trial (ASPREO Trial)",
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"title": "An Exploration of Gated and Non-Gated Dynamic PET/CT Imaging",
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"sponsor_name": "Washington University School of Medicine",
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"title": "Aspirin Plus Rivaroxaban Efficacy and Safety in Embolic Stroke of Undetermined Source: A Randomized, Placebo Controlled, Outcome Assessor Blind, Feasibility Study",
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"title": "An Investigator-Initiated, Double-Blind, Patient-Controlled, Randomized Control Trial Comparing the Effectiveness of Liposomal Bupivacaine to a Solution of Bupivacaine, Epinephrine Clonidine and Dexamethasone in Bilateral, Single Shot, Erector Spinae Plane Blocks During Oncoplastic Breast Surgery",
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"title": "A Phase 3, Randomized, Observer-Blinded, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine (SARS-CoV-2 rS) With Matrix-M1™ Adjuvant in Adult Participants ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to < 18 Years)",
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"title": "A Phase 2 Study of Oral LOXO-305 in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) or Non-Hodgkin Lymphoma (NHL)",
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"title": "Investigation of Central Priming Prior to Training of the Upper Extremity in Chronic Stroke",
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"title": "Assessment of Safety, Tolerability, and Efficacy of Donanemab in Early Symptomatic Alzheimer's Disease",
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"title": "An Open-label Multicenter Study to Assess Response to COVID-19 Vaccine in Participants With Multiple Sclerosis Treated With Ofatumumab 20 mg Subcutaneously",
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"title": "Multicenter, Randomized, Parallel Group, Phase 2 to Establish the Efficacy and Safety of Combinations of CBP501, Cisplatin, and Nivolumab for ≥3rd Line Treatment of Patients With Exocrine Pancreatic Cancer and WBC <10,000/mm3 at Screening",
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"title": "A Multiple-dose, Steady-state, Double-blind, Ascending Dose, Safety, Tolerability, Pharmacokinetic Study of AL001 in Patients With Mild to Moderate Alzheimer's Disease and Healthy Adult Subjects (\"MAD Study\")",
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"title": "Investigation and Comparison of the Antibody Response Initiated by Recombinant, Cell-Based and Egg-Based Influenza Vaccines",
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"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03620019",
"title": "Phase 2 Study of Denosumab in Combination With a PD-1 Inhibitor in Subjects With Stage III/IV Melanoma",
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"start_date": "2018-09-10",
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"registry_id": "NCT03897296",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03897296",
"title": "Study of Normative Metrics of High-resolution Anorectal Manometry With the Use of Water-perfused Catheter in a Russian Population Without Signs of Functional and Organic Anorectal Disorders",
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"start_date": "2019-04-15",
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"sponsor_name": "Russian Academy of Medical Sciences",
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"title": "ALTITUDE NASH: A Phase 2, Randomized, Multi-Center, Open-Label Study to Evaluate the Safety and Efficacy of Rencofilstat in Adult Subjects With Nonalcoholic Steatohepatitis Stage 3 Fibrosis",
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"sponsor_name": "Hepion Pharmaceuticals, Inc.",
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"title": "A Phase 2, Randomized, Placebo-Controlled, Double-Blind, Adaptive, Parallel Group Clinical Study to Evaluate the Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery",
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"sponsor_name": "Guard Therapeutics AB",
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"title": "Closing the Gap Between Identification and Treatment of Cervical Abnormalities in Lima, Perú Through Integraton of Pocket Colposcopy, Telemedicine and Visual Counseling",
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"title": "Medtronic PERIcardial SurGical AOrtic Valve ReplacemeNt Pivotal Trial A Multi-center, Non-randomized Trial to Determine the Safety and Effectiveness of the Model 400 Aortic Valve Bioprosthesis in Patients With Aortic Valve Disease",
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"title": "A Biomarker Validation Study to Establish Whether Serial Flow Cytometric Measurements Predict Clinical Response to Sirolimus and MEC (Mitoxantrone Etoposide Cytarabine) Treatment in Patients With High-Risk Acute Myelogenous Leukemia",
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"title": "Oral ONC201 in Adult Recurrent Glioblastoma",
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"start_date": "2016-01-31",
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"sponsor_name": "Chimerix",
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"title": "A Phase II, Multicenter, Open-label, Randomized Two-year Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis.",
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"start_date": "2018-01-11",
"completion_date": "2023-04-17",
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"sponsor_name": "Novartis Pharmaceuticals",
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"title": "Phase III Multicenter Open-label Randomized Clinical Trial Comparing Everolimus and Low Dose Tacrolimus to Tacrolimus and Mycophenolate Mofetil at 6 mo Post-Transplant to Prevent Long-term Complications After Pediatric Heart Transplantation",
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"start_date": "2018-01-29",
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"sponsor_name": "Boston Children’s Hospital",
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"title": "A Prospective, Double-Blind, Placebo-controlled Study of Suramin in Subjects With Furosemide-Resistant Acute Kidney Injury (AKI): Efficacy in Preventing Dialysis Dependent AKI",
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"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04937881",
"title": "Comparison of Pharmacokinetics of Tenofovir Alafenamide (TAF) With Tenofovir Disoproxil (TDF) in Pregnant and Postpartum Women and Their Infants in PrEP-PP Study",
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"start_date": "2022-06-13",
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"sponsor_name": "University of California, Los Angeles",
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"registry_id": "NCT05005182",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05005182",
"title": "Phase II Study to Determine the Efficacy and Safety of Luspatercept (ACE-536) in Patients With Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic/Myeloproliferative Neoplasms, Unclassifiable With Ring Sideroblasts (MDS/MPN-U With RS)",
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"start_date": "2023-02-20",
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"registry_id": "NCT03138603",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03138603",
"title": "Metoprolol to Reduce Perioperative Myocardial Injury",
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"start_date": "2016-12-31",
"completion_date": "2023-04-18",
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"sponsor_name": "University of Chicago",
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"title": "Efficacy, Safety and Mechanism of Action of Lanifibranor (IVA337) in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease",
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"start_date": "2018-08-14",
"completion_date": "2023-04-18",
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"sponsor_name": "University of Florida",
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"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04599101",
"title": "Effectiveness of Nasal Suction in Infants With Bronchiolitis Using a NoseFrida vs. Bulb Syringe",
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"start_date": "2020-11-21",
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"sponsor_name": "William Beaumont Hospitals",
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"title": "Effect of Semaglutide 2.4 mg Once Weekly on Function and Symptoms in Subjects With Obesity-related Heart Failure With Preserved Ejection Fraction",
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"start_date": "2021-03-16",
"completion_date": "2023-04-18",
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"sponsor_name": "Novo Nordisk A/S",
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"registry_id": "NCT04920916",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04920916",
"title": "Safety and Efficacy of the Treatment of Hospitalized Patients With COVID 19 Infection With an Inhibitor of IL-4 and IL-13 Signaling: A Phase IIa Trial",
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"start_date": "2021-05-25",
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"sponsor_name": "University of Virginia",
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"title": "Role of Continuous Glucose Monitoring Systems (CGMS) for Intrapartum Metabolic Control in Gestational Diabetic (GDM)Women",
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"start_date": "2021-11-01",
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"registry_id": "NCT04905290",
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"title": "Conduction System Pacing Optimized Therapy Study",
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"start_date": "2021-11-27",
"completion_date": "2023-04-18",
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"sponsor_name": "Medtronic Cardiac Rhythm and Heart Failure",
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"registry_id": "NCT05208905",
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"title": "LIFE-BTK Pharmacokinetics (PK) Sub-study",
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"sponsor_name": "Abbott Medical Devices",
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"registry_id": "NCT05559905",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT05559905",
"title": "A Phase 2a Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-4482 in Healthy Participants Inoculated With Experimental Respiratory Syncytial Virus",
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"start_date": "2022-11-02",
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"sponsor_name": "Merck Sharp & Dohme LLC",
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{
"registry_id": "NCT02769962",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02769962",
"title": "A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in Patients With Relapsed/Refractory Small Cell Lung, Bladder and Prostate Cancers",
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"start_date": "2016-05-09",
"completion_date": "2023-04-19",
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"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
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{
"registry_id": "NCT03156010",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03156010",
"title": "Oculomotor Assessment of Traumatic Brain Injury (TBI)",
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"start_date": "2017-09-18",
"completion_date": "2023-04-19",
"has_results": false,
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"sponsor_name": "Walter Reed National Military Medical Center",
"sponsor_slug": "walter-reed-national-military-medical-center",
"status": "reported",
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}