HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 49217,
"recordsTotal": 49217,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=-days_late&start=48600",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=-days_late&start=48000",
"results": [
{
"registry_id": "NCT07008469",
"publication_url": "https://clinicaltrials.gov/study/NCT07008469",
"title": "A Global Phase 3 Open-Label Extension Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Intravenous AOC 1001 for the Treatment of Myotonic Dystrophy Type 1",
"has_exemption": false,
"start_date": "2025-07-25",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Avidity Biosciences, Inc.",
"sponsor_slug": "avidity-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219485",
"publication_url": "https://clinicaltrials.gov/study/NCT07219485",
"title": "An Open-Label Study to Evaluate Safety of Pitolisant in Participants With Prader-Willi Syndrome",
"has_exemption": false,
"start_date": "2025-08-20",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Harmony Biosciences Management, Inc.",
"sponsor_slug": "harmony-biosciences-management-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06948019",
"publication_url": "https://clinicaltrials.gov/study/NCT06948019",
"title": "Safety and Efficacy of AAV9/AP4B1 For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of Stereotactic Intra-cisterna Magna Administration",
"has_exemption": false,
"start_date": "2025-08-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BlackfinBio Ltd",
"sponsor_slug": "blackfinbio-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07185256",
"publication_url": "https://clinicaltrials.gov/study/NCT07185256",
"title": "A Phase 1b/2a, Open-Label, Dose-Exploration Basket Study to Investigate the Safety and Tolerability of Subretinally Injected OPGx-BEST1 Administered in Patients With Either Autosomal-Dominant BEST1 Disease (Best Vitelliform Macular Dystrophy [BVMD]) or Autosomal-Recessive Bestrophinopathy (ARB)",
"has_exemption": false,
"start_date": "2025-09-25",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Opus Genetics, Inc",
"sponsor_slug": "opus-genetics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07165028",
"publication_url": "https://clinicaltrials.gov/study/NCT07165028",
"title": "A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07303738",
"publication_url": "https://clinicaltrials.gov/study/NCT07303738",
"title": "The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations: A Novel Intervention for Children at Risk for Aspiration-Associated Complications (Aim 1)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096297",
"publication_url": "https://clinicaltrials.gov/study/NCT07096297",
"title": "A Phase II Study of Luspatercept Plus Darbepoetin Alfa in Non-mutated SF3B1 Lower-risk Myelodysplastic Syndromes",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07397559",
"publication_url": "https://clinicaltrials.gov/study/NCT07397559",
"title": "Spatiotemporal Control of Transcutaneous Spinal Cord Stimulation for Motor Function in SCI",
"has_exemption": false,
"start_date": "2026-01-19",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07022405",
"publication_url": "https://clinicaltrials.gov/study/NCT07022405",
"title": "Stratified Pharmacological Approaches for Regulating Circuit-Level Effects Study",
"has_exemption": false,
"start_date": "2026-01-23",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07029529",
"publication_url": "https://clinicaltrials.gov/study/NCT07029529",
"title": "Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-05-12",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07434492",
"publication_url": "https://clinicaltrials.gov/study/NCT07434492",
"title": "Smart Ankle-Foot Orthosis and 5-Azacitidine to Enhance Gait and Community Mobility for Children With Cerebral Palsy",
"has_exemption": false,
"start_date": "2026-05-28",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shirley Ryan AbilityLab",
"sponsor_slug": "shirley-ryan-abilitylab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07598643",
"publication_url": "https://clinicaltrials.gov/study/NCT07598643",
"title": "Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07450677",
"publication_url": "https://clinicaltrials.gov/study/NCT07450677",
"title": "Neurobehavioral Effects of Visual Assistive Technologies",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227779",
"publication_url": "https://clinicaltrials.gov/study/NCT07227779",
"title": "A PHASE 2 NOVEL ANTIMICROBIAL COMBINATION THERAPY TO TREAT TUBERCULOUS MENINGITIS",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07303868",
"publication_url": "https://clinicaltrials.gov/study/NCT07303868",
"title": "The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations: A Novel Intervention for Children at Risk for Aspiration-Associated Complications (Aim 2)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06131502",
"publication_url": "https://clinicaltrials.gov/study/NCT06131502",
"title": "ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy for Treatment of Obsessive-Compulsive Disorder",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07619365",
"publication_url": "https://clinicaltrials.gov/study/NCT07619365",
"title": "Phase II Trial Evaluating Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer (MBC)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06841679",
"publication_url": "https://clinicaltrials.gov/study/NCT06841679",
"title": "A Multi-national, Open-label, Randomized Phase II/III Clinical Study of Utidelone Capsule (UTD2) Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-08-28",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Beijing Biostar Pharmaceuticals Co., Ltd.",
"sponsor_slug": "beijing-biostar-pharmaceuticals-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07164131",
"publication_url": "https://clinicaltrials.gov/study/NCT07164131",
"title": "Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams",
"has_exemption": false,
"start_date": "2025-09-15",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06827990",
"publication_url": "https://clinicaltrials.gov/study/NCT06827990",
"title": "Evaluation of the GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07153003",
"publication_url": "https://clinicaltrials.gov/study/NCT07153003",
"title": "Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty: A Prospective Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228624",
"publication_url": "https://clinicaltrials.gov/study/NCT07228624",
"title": "Peri-Hematopoietic Cell Transplantation Ruxolitinib in Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes",
"has_exemption": false,
"start_date": "2026-02-04",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288450",
"publication_url": "https://clinicaltrials.gov/study/NCT07288450",
"title": "Terazosin And Metabolic Engagement in Parkinson's Disease",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Nandakumar Narayanan",
"sponsor_slug": "nandakumar-narayanan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06794944",
"publication_url": "https://clinicaltrials.gov/study/NCT06794944",
"title": "Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07470489",
"publication_url": "https://clinicaltrials.gov/study/NCT07470489",
"title": "A Multi-Center Single-Arm Phase 2 Trial Of Zanzalintinib In Combination With Cemiplimab In BRAF Wild-Type Anaplastic Thyroid Cancer: The ZEPHYR Trial",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05987241",
"publication_url": "https://clinicaltrials.gov/study/NCT05987241",
"title": "MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer",
"has_exemption": false,
"start_date": "2024-02-02",
"completion_date": "2030-09-02",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06577025",
"publication_url": "https://clinicaltrials.gov/study/NCT06577025",
"title": "A Phase 2, Open-label Study to Evaluate the Efficacy and Safety of Different Sequences of Ciltacabtagene Autoleucel (Cilta-cel), Talquetamab SC in Combination With Daratumumab SC (Tal-D) and Teclistamab SC in Combination With Daratumumab SC (Tec-D) Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) in Participants With Standard-risk Newly Diagnosed Multiple Myeloma",
"has_exemption": false,
"start_date": "2024-08-20",
"completion_date": "2030-09-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07630714",
"publication_url": "https://clinicaltrials.gov/study/NCT07630714",
"title": "A Multicenter, Open-Label, Phase II Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus",
"has_exemption": false,
"start_date": "2026-07-28",
"completion_date": "2030-09-03",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04246086",
"publication_url": "https://clinicaltrials.gov/study/NCT04246086",
"title": "A Phase Ib/II, Open-Label, Multicenter Study With a Non-Randomized Stage Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab Plus Lenalidomide (+Len), and a Randomized Stage Evaluating the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Patients With Follicular Lymphoma",
"has_exemption": false,
"start_date": "2020-08-12",
"completion_date": "2030-09-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03068442",
"publication_url": "https://clinicaltrials.gov/study/NCT03068442",
"title": "Amyloid Deposition and Preexisting Vulnerable Carotid Plaque Features Predicting Cognitive Improvement After Surgery",
"has_exemption": false,
"start_date": "2017-02-17",
"completion_date": "2030-09-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Scott Mcnally",
"sponsor_slug": "scott-mcnally",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07470879",
"publication_url": "https://clinicaltrials.gov/study/NCT07470879",
"title": "A PHASE 2 OPEN-LABEL, SINGLE ARM STUDY TO EVALUATE THE EFFICACY, PHARMACOKINETICS, AND SAFETY OF ETRASIMOD IN PEDIATRIC PARTICIPANTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS",
"has_exemption": false,
"start_date": "2026-05-30",
"completion_date": "2030-09-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07361497",
"publication_url": "https://clinicaltrials.gov/study/NCT07361497",
"title": "ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.",
"has_exemption": false,
"start_date": "2026-03-16",
"completion_date": "2030-09-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594106",
"publication_url": "https://clinicaltrials.gov/study/NCT07594106",
"title": "Phase 1/2 Study of REGN15505 (a PSMAx4-1BB Bispecific Antibody) Administered Alone or in Combination With Cemiplimab or REGN4336 (a PSMAxCD3 Bispecific Antibody) in Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma",
"has_exemption": false,
"start_date": "2026-05-25",
"completion_date": "2030-09-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05335876",
"publication_url": "https://clinicaltrials.gov/study/NCT05335876",
"title": "Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 IT or OAV101 IV in Clinical Trials",
"has_exemption": false,
"start_date": "2022-12-19",
"completion_date": "2030-09-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07173803",
"publication_url": "https://clinicaltrials.gov/study/NCT07173803",
"title": "The Progressive Supranuclear Palsy Clinical Trial Platform",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-09-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Adam Boxer",
"sponsor_slug": "adam-boxer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07217665",
"publication_url": "https://clinicaltrials.gov/study/NCT07217665",
"title": "The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-09-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Adam Boxer",
"sponsor_slug": "adam-boxer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07264283",
"publication_url": "https://clinicaltrials.gov/study/NCT07264283",
"title": "The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-09-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Adam Boxer",
"sponsor_slug": "adam-boxer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02559778",
"publication_url": "https://clinicaltrials.gov/study/NCT02559778",
"title": "A Study Using Molecular Guided Therapy With Induction Chemotherapy Followed by a Randomized Controlled Trial of Standard Immunotherapy With or Without DFMO Followed by DFMO Maintenance for Subjects With Newly Diagnosed High-Risk Neuroblastoma",
"has_exemption": false,
"start_date": "2015-09-30",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Giselle Sholler",
"sponsor_slug": "giselle-sholler",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03143374",
"publication_url": "https://clinicaltrials.gov/study/NCT03143374",
"title": "Positron Emission Tomography (PET) Imaging of Tau Pathology in Neurodegenerative Disease",
"has_exemption": false,
"start_date": "2016-08-23",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03034811",
"publication_url": "https://clinicaltrials.gov/study/NCT03034811",
"title": "Persona Partial Knee Clinical Outcomes Study",
"has_exemption": false,
"start_date": "2017-02-08",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zimmer Biomet",
"sponsor_slug": "zimmer-biomet",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03424005",
"publication_url": "https://clinicaltrials.gov/study/NCT03424005",
"title": "A Phase Ib/II, Open-label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic Breast Cancer (Morpheus-panBC)",
"has_exemption": false,
"start_date": "2018-03-30",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03126916",
"publication_url": "https://clinicaltrials.gov/study/NCT03126916",
"title": "A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or ALK Inhibitor Therapy Added to Intensive Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma (NBL)",
"has_exemption": false,
"start_date": "2018-05-14",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04685616",
"publication_url": "https://clinicaltrials.gov/study/NCT04685616",
"title": "A Randomised Phase III Trial With a PET Response Adapted Design Comparing ABVD +/- ISRT With A2VD +/- ISRT in Patients With Previously Untreated Stage IA/IIA Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2022-04-14",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University College, London",
"sponsor_slug": "university-college-london",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05450653",
"publication_url": "https://clinicaltrials.gov/study/NCT05450653",
"title": "Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia (CDH)",
"has_exemption": false,
"start_date": "2022-09-18",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Aimen F. Shaaban, MD",
"sponsor_slug": "aimen-f-shaaban-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06109272",
"publication_url": "https://clinicaltrials.gov/study/NCT06109272",
"title": "A Phase 2/3, Randomized Study to Evaluate the Dose Optimization, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab in Subjects With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Who Have Not Previously Received Systemic Treatment",
"has_exemption": false,
"start_date": "2024-01-11",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06441955",
"publication_url": "https://clinicaltrials.gov/study/NCT06441955",
"title": "Covid-19 Long Haul Syndrome: Undiagnosed Disorder Post Covid-19 Alternative Treatment Study.",
"has_exemption": false,
"start_date": "2024-03-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Well- Konnect Healthcare Services and Research Firm",
"sponsor_slug": "well-konnect-healthcare-services-and-research-firm",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05673018",
"publication_url": "https://clinicaltrials.gov/study/NCT05673018",
"title": "REACH Study: Galleri® in the Medicare Population.",
"has_exemption": false,
"start_date": "2024-07-12",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GRAIL, Inc.",
"sponsor_slug": "grail-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06475989",
"publication_url": "https://clinicaltrials.gov/study/NCT06475989",
"title": "A Randomized Phase III Study of BRAF-Targeted Therapy vs Cabozantinib in RAI-Refractory Differentiated Thyroid Cancer With BRAF V600Em",
"has_exemption": false,
"start_date": "2024-08-22",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06518785",
"publication_url": "https://clinicaltrials.gov/study/NCT06518785",
"title": "Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-01-07",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06861244",
"publication_url": "https://clinicaltrials.gov/study/NCT06861244",
"title": "PNOC031: Protocol for Embryonal Tumor With Multilayered Rosettes (ETMR)",
"has_exemption": false,
"start_date": "2025-03-06",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953882",
"publication_url": "https://clinicaltrials.gov/study/NCT06953882",
"title": "SELECT: A Phase II Adjuvant Trial Evaluating the Impact of Omitting Chemotherapy Based on Patient's Selection for Moderate to High-Anatomical Risk, Low-Genomic Risk, ER-Positive, HER2- Negative Breast Cancer With a Combination Regimen of Ribociclib and Optimized Endocrine Therapy",
"has_exemption": false,
"start_date": "2025-07-09",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096362",
"publication_url": "https://clinicaltrials.gov/study/NCT07096362",
"title": "A Phase 2 Study Assessing Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-09-09",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06997081",
"publication_url": "https://clinicaltrials.gov/study/NCT06997081",
"title": "Elranatamab, Lenalidomide, Dexamethasone in Newly Diagnosed Multiple Myeloma, a Clinical and Correlative Phase 2 Study",
"has_exemption": false,
"start_date": "2025-09-16",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07181109",
"publication_url": "https://clinicaltrials.gov/study/NCT07181109",
"title": "ZENITH: A Phase 3 Global, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Zilebesiran in Addition to Standard of Care in Reducing Major Adverse Cardiovascular Events in Adult Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158476",
"publication_url": "https://clinicaltrials.gov/study/NCT07158476",
"title": "Efficacy of Methylprednisolone for Pain Control After ACL Repair: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-10-21",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Louis University",
"sponsor_slug": "st-louis-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221539",
"publication_url": "https://clinicaltrials.gov/study/NCT07221539",
"title": "Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation",
"has_exemption": false,
"start_date": "2025-10-24",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214207",
"publication_url": "https://clinicaltrials.gov/study/NCT07214207",
"title": "Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking",
"has_exemption": false,
"start_date": "2025-12-04",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University",
"sponsor_slug": "ohio-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07155187",
"publication_url": "https://clinicaltrials.gov/study/NCT07155187",
"title": "Phase 2/3 Open Label Randomized Study of Telisotuzumab Adizutecan Compared to Standard of Care in Subjects With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer After Progression on a Third-Generation EGFR TKI",
"has_exemption": false,
"start_date": "2025-12-10",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07424846",
"publication_url": "https://clinicaltrials.gov/study/NCT07424846",
"title": "Xylitol and the Prevention of Periodontal Disease and Preterm Birth (XaPPP) Trial",
"has_exemption": false,
"start_date": "2026-03-26",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07365241",
"publication_url": "https://clinicaltrials.gov/study/NCT07365241",
"title": "A Phase 3 Randomized, Open Label, Multicenter Study to Evaluate the Safety and Efficacy of ABBV-706 Versus Standard of Care in Subjects With Relapsed/Refractory Small Cell Lung Cancer (SCLC)",
"has_exemption": false,
"start_date": "2026-04-14",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225985",
"publication_url": "https://clinicaltrials.gov/study/NCT07225985",
"title": "Pralatrexate and Bendamustine With 3 Gy TBI as a New Reduced Intensity Conditioning (RIC) Regimen for Allogeneic HCT for T-Cell Lymphoma Patients Who Are in Untreated R/R, or in Remission With MRD",
"has_exemption": false,
"start_date": "2026-04-27",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07088120",
"publication_url": "https://clinicaltrials.gov/study/NCT07088120",
"title": "PRecision-Controlled Ventilation to Enhance Cardiac Arrest Intervention and Survival IN CPR: A Multi-Center Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218575",
"publication_url": "https://clinicaltrials.gov/study/NCT07218575",
"title": "A Randomized, Placebo Controlled Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07642635",
"publication_url": "https://clinicaltrials.gov/study/NCT07642635",
"title": "Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With Duchenne Muscular Dystrophy",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07485335",
"publication_url": "https://clinicaltrials.gov/study/NCT07485335",
"title": "Implementation and Effectiveness of A Bundled Intervention to End Opioid Overdoses by Increasing Treatment Uptake Post Discharge",
"has_exemption": false,
"start_date": "2026-09-07",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07337655",
"publication_url": "https://clinicaltrials.gov/study/NCT07337655",
"title": "A Phase II/III Clinical Trial Evaluating the Efficacy and Safety of Aspirin and Lansoprazole in High-Risk Pregnant Women for the Prevention of Preterm Birth: A Biomarker-Enriched Design",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07568860",
"publication_url": "https://clinicaltrials.gov/study/NCT07568860",
"title": "Sleep-Driven Adaptive Neuromodulation in Lennox-Gastaut Syndrome",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06034821",
"publication_url": "https://clinicaltrials.gov/study/NCT06034821",
"title": "Rapid Reversal of Suicidal Depression: Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan (REaKT-SD)",
"has_exemption": false,
"start_date": "2023-10-01",
"completion_date": "2030-10-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07240922",
"publication_url": "https://clinicaltrials.gov/study/NCT07240922",
"title": "The Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (DRIVE III) Study - a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2030-10-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Hong Kong",
"sponsor_slug": "the-university-of-hong-kong",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06942442",
"publication_url": "https://clinicaltrials.gov/study/NCT06942442",
"title": "A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma",
"has_exemption": false,
"start_date": "2025-10-22",
"completion_date": "2030-10-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarcoma Alliance for Research through Collaboration",
"sponsor_slug": "sarcoma-alliance-for-research-through-collaboration",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07075510",
"publication_url": "https://clinicaltrials.gov/study/NCT07075510",
"title": "A Phase I/II Study of Subcutaneous Daratumumab Administration in the Anterior Upper Thigh Vs Abdomen in Patients With Plasma Cell Disorders",
"has_exemption": false,
"start_date": "2025-10-23",
"completion_date": "2030-10-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07209189",
"publication_url": "https://clinicaltrials.gov/study/NCT07209189",
"title": "Neoadjuvant Chemotherapy and PD-1 Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2030-10-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07098364",
"publication_url": "https://clinicaltrials.gov/study/NCT07098364",
"title": "A Phase 1/2 Open-Label Study Evaluating the Safety and Efficacy of ST-067 in Combination With CD19-Directed CAR T-Cell Therapy in Patients With Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL)",
"has_exemption": false,
"start_date": "2025-12-27",
"completion_date": "2030-10-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07192237",
"publication_url": "https://clinicaltrials.gov/study/NCT07192237",
"title": "Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-09-27",
"completion_date": "2030-10-12",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04270409",
"publication_url": "https://clinicaltrials.gov/study/NCT04270409",
"title": "A Phase 3 Randomized, Open-label, Multicenter Study of Isatuximab (SAR650984) in Combination With Lenalidomide and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With High-risk Smoldering Multiple Myeloma",
"has_exemption": false,
"start_date": "2020-06-16",
"completion_date": "2030-10-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06525766",
"publication_url": "https://clinicaltrials.gov/study/NCT06525766",
"title": "Single Arm Pilot Trial of Adaptive Therapy (AT) With Capecitabine for the Treatment of Metastatic Estrogen Receptor Positive, Hormone Refractory Breast Cancer",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2030-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05623020",
"publication_url": "https://clinicaltrials.gov/study/NCT05623020",
"title": "AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE VERSUS DARATUMUMAB + BORTEZOMIB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA",
"has_exemption": false,
"start_date": "2022-11-10",
"completion_date": "2030-10-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06669117",
"publication_url": "https://clinicaltrials.gov/study/NCT06669117",
"title": "A First-In-Human (FIH) Phase I/II Open-label, Multicentre, Dose Escalation and Expansion Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors Including Non-small Cell Lung Cancer (NSCLC) Harboring Mesenchymal-Epithelial Transition (MET) Alterations",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2030-10-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Pierre Fabre Medicament",
"sponsor_slug": "pierre-fabre-medicament",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04545957",
"publication_url": "https://clinicaltrials.gov/study/NCT04545957",
"title": "Judging MR Simulation Procedures: A Phase I-II Study of the Use of Magnetic Resonance Imaging Simulation in the Planning of Radiation Treatments",
"has_exemption": false,
"start_date": "2020-10-14",
"completion_date": "2030-10-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06646289",
"publication_url": "https://clinicaltrials.gov/study/NCT06646289",
"title": "An Open-label, Multicenter, Phase 2 Follow-on Study for Second Eye Treatment of Patients Previously Treated With a Recombinant Adeno-associated Virus Vector (AAV5 hRKp.RPGR) for Gene Therapy of Adults and Children With X-linked Retinitis Pigmentosa Owing to Defects in Retinitis Pigmentosa GTPase Regulator (RPGR)",
"has_exemption": false,
"start_date": "2024-10-10",
"completion_date": "2030-10-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07363694",
"publication_url": "https://clinicaltrials.gov/study/NCT07363694",
"title": "AN INTERVENTIONAL PHASE 2/3, RANDOMIZED, DOUBLE-BLIND, THIRD PARTY-UNBLINDED, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO INVESTIGATE EFFICACY AND SAFETY OF PF-07275315 IN ADULT PARTICIPANTS WITH MODERATE-TO-SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)",
"has_exemption": false,
"start_date": "2026-02-11",
"completion_date": "2030-10-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07468136",
"publication_url": "https://clinicaltrials.gov/study/NCT07468136",
"title": "Phase I/IIa Trial of Retifanlimab and Difluoromethylornithine (DFMO) in Patients With Progressive High-Grade Glioma",
"has_exemption": false,
"start_date": "2026-04-24",
"completion_date": "2030-10-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222956",
"publication_url": "https://clinicaltrials.gov/study/NCT07222956",
"title": "An Open-label, Single-center Study of Remibrutinib Using Ultra High-field (7T) MR Imaging in Relapsing or Progressive MS (RemiSeven)",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Moein Amin",
"sponsor_slug": "moein-amin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00160732",
"publication_url": "https://clinicaltrials.gov/study/NCT00160732",
"title": "Allogenic Islet Cells (Human, U. of Chicago) Administered Via Intraportal Infusion; and Immunosuppressive Therapy",
"has_exemption": false,
"start_date": "2003-10-31",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT04062266",
"publication_url": "https://clinicaltrials.gov/study/NCT04062266",
"title": "Phase II Study of 5-Azacytidine (AZA) + Venetoclax as Maintenance Therapy in Patients With AML in Remission",
"has_exemption": false,
"start_date": "2019-09-13",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04584853",
"publication_url": "https://clinicaltrials.gov/study/NCT04584853",
"title": "PreOperative Endocrine Therapy for Individualised Care With Abemaciclib",
"has_exemption": false,
"start_date": "2020-12-23",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Institute of Cancer Research, United Kingdom",
"sponsor_slug": "institute-of-cancer-research-united-kingdom",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04948619",
"publication_url": "https://clinicaltrials.gov/study/NCT04948619",
"title": "Immune Function and Response to Vaccination Following Completion of Cancer Directed Systemic Therapy in Pediatric Patients With Cancer",
"has_exemption": false,
"start_date": "2022-08-08",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05371093",
"publication_url": "https://clinicaltrials.gov/study/NCT05371093",
"title": "A Phase 3 Randomized, Open-Label, Multicenter Study Evaluating the Efficacy of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Subjects With Relapsed/Refractory Follicular Lymphoma",
"has_exemption": false,
"start_date": "2022-09-22",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07142408",
"publication_url": "https://clinicaltrials.gov/study/NCT07142408",
"title": "The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention",
"has_exemption": false,
"start_date": "2023-03-13",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cooper Health System",
"sponsor_slug": "the-cooper-health-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05933395",
"publication_url": "https://clinicaltrials.gov/study/NCT05933395",
"title": "Genetically-informed Therapy for ER+ Breast Cancer in a Post-CDK4/6 Inhibitor Setting: a Phase II Umbrella Study (GERTRUDE)",
"has_exemption": false,
"start_date": "2024-09-23",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dartmouth-Hitchcock Medical Center",
"sponsor_slug": "dartmouth-hitchcock-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06121180",
"publication_url": "https://clinicaltrials.gov/study/NCT06121180",
"title": "A Phase II Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2024-11-04",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06628310",
"publication_url": "https://clinicaltrials.gov/study/NCT06628310",
"title": "A Phase 2 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination With Fluorouracil, Leucovorin, and Budigalimab as First-Line Treatment in Subjects With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (AndroMETa-GEA-977)",
"has_exemption": false,
"start_date": "2024-12-13",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06626516",
"publication_url": "https://clinicaltrials.gov/study/NCT06626516",
"title": "A Phase I/II Study of Tebentafusp-tebn in Combination With Liver-Directed Therapies for the Treatment of Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Jefferson University",
"sponsor_slug": "thomas-jefferson-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07216248",
"publication_url": "https://clinicaltrials.gov/study/NCT07216248",
"title": "A Phase II Randomized, Decentralized, De-escalation Study in Patients With Metastatic Hormone-Sensitive Prostate Cancer Achieving Optimal PSA Response (OPTIMAS)",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05213676",
"publication_url": "https://clinicaltrials.gov/study/NCT05213676",
"title": "Inhaled Nitric Oxide (iNO) for Congenital Diaphragmatic Hernia (CDH) - The \"NoNO Trial\" - a Multi-center, De-implementation, Stepped-wedge, Cluster-randomized Trial Within an Established Collaborative",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07150715",
"publication_url": "https://clinicaltrials.gov/study/NCT07150715",
"title": "Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide Combined With Metastasis-Directed Stereotactic Body Radiotherapy for Oligorecurrent Prostate Adenocarcinoma (ANDROMEDA)",
"has_exemption": false,
"start_date": "2025-12-12",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07265947",
"publication_url": "https://clinicaltrials.gov/study/NCT07265947",
"title": "A Phase 2A/B, Multi-center, Open-Label Study Evaluating the Efficacy and Safety of Dabogratinib (TYRA-300) in Participants With Low Grade Upper Tract Urothelial Carcinoma (SURF303)",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tyra Biosciences, Inc",
"sponsor_slug": "tyra-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07015190",
"publication_url": "https://clinicaltrials.gov/study/NCT07015190",
"title": "A Randomized, Phase 3, Open-label Study of Neoadjuvant Darovasertib in Subjects With Primary Non-metastatic Uveal Melanoma (OptimUM-10)",
"has_exemption": false,
"start_date": "2026-01-25",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IDEAYA Biosciences",
"sponsor_slug": "ideaya-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03244072",
"publication_url": "https://clinicaltrials.gov/study/NCT03244072",
"title": "Safety and Efficacy of Intracameral Zimoxin (0.1% Moxifloxacin Solution) for Prevention of Endophthalmitis After Cataract Surgery",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jason Ahee, M.D.",
"sponsor_slug": "jason-ahee-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07148843",
"publication_url": "https://clinicaltrials.gov/study/NCT07148843",
"title": "Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07528690",
"publication_url": "https://clinicaltrials.gov/study/NCT07528690",
"title": "Microbiota Transplant Therapy to Prevent HE Recurrence in a Phase 2B Multi-Center Trial of Veterans With Cirrhosis",
"has_exemption": false,
"start_date": "2026-10-30",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06905626",
"publication_url": "https://clinicaltrials.gov/study/NCT06905626",
"title": "Prevention of Obesity in Adolescents and Young Adults",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04760860",
"publication_url": "https://clinicaltrials.gov/study/NCT04760860",
"title": "a Randomized, Double Blind, Placebo Controlled Clinical Trial Exploring the Target Engagement and Tolerability of Terazosin Hydrochloride in Patients With Dementia With Lewy Bodies",
"has_exemption": false,
"start_date": "2027-10-31",
"completion_date": "2030-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Qiang Zhang",
"sponsor_slug": "qiang-zhang",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06458036",
"publication_url": "https://clinicaltrials.gov/study/NCT06458036",
"title": "Selpercatinib to Enhance RAI Avidity in Children, Adolescents, and Young Adults With Newly Diagnosed Differentiated Thyroid Cancers Harboring RET Fusions",
"has_exemption": false,
"start_date": "2024-07-29",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06541262",
"publication_url": "https://clinicaltrials.gov/study/NCT06541262",
"title": "Phase I/II Study of Silmitasertib (CX-4945) in Combination With Chemotherapy in Children and Young Adults With Relapsed Refractory Solid Tumors",
"has_exemption": false,
"start_date": "2024-10-30",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Milton S. Hershey Medical Center",
"sponsor_slug": "milton-s-hershey-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06906887",
"publication_url": "https://clinicaltrials.gov/study/NCT06906887",
"title": "PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer",
"has_exemption": false,
"start_date": "2025-06-17",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06926595",
"publication_url": "https://clinicaltrials.gov/study/NCT06926595",
"title": "Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) With Low-Dose Post-Transplant Cyclophosphamide for Prophylaxis of Graft-versus-Host Disease in Hematological Malignancies",
"has_exemption": false,
"start_date": "2026-03-09",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Milton S. Hershey Medical Center",
"sponsor_slug": "milton-s-hershey-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06934655",
"publication_url": "https://clinicaltrials.gov/study/NCT06934655",
"title": "Early Re-Initiation of Semaglutide Post Sleeve Gastrectomy in Youth",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Los Angeles",
"sponsor_slug": "childrens-hospital-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07136428",
"publication_url": "https://clinicaltrials.gov/study/NCT07136428",
"title": "A Single Arm, Open-label Phase Ib/II Study of Asciminib in HER2+ Breast Cancer Brain Metastases (ASCENdANT)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07322341",
"publication_url": "https://clinicaltrials.gov/study/NCT07322341",
"title": "A Phase 2 Trial of SX-682 and Atezolizumab in Patients With Advanced NSCLC Who Progressed on Prior Chemotherapy and Immune Checkpoint Inhibitor (ICI) Therapy",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03750227",
"publication_url": "https://clinicaltrials.gov/study/NCT03750227",
"title": "Pre-Operative vs. Post-Operative Stereotactic Radiosurgery for Operative Metastatic Brain Tumors",
"has_exemption": false,
"start_date": "2018-11-19",
"completion_date": "2030-11-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221149",
"publication_url": "https://clinicaltrials.gov/study/NCT07221149",
"title": "ROSETTA Gastric-204: A Blinded, Randomized, Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma",
"has_exemption": false,
"start_date": "2026-03-13",
"completion_date": "2030-11-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07517705",
"publication_url": "https://clinicaltrials.gov/study/NCT07517705",
"title": "Feasibility of MRD-Adapted Mid-Cycle Low-Dose Radiation Combined With Frontline R-Chemoimmunotherapy in Diffuse Large B-Cell Lymphoma (MRD XRT)",
"has_exemption": false,
"start_date": "2026-06-12",
"completion_date": "2030-11-12",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06995508",
"publication_url": "https://clinicaltrials.gov/study/NCT06995508",
"title": "Managing Anorexia During Chemoradiation With Olanzapine (MACRO)",
"has_exemption": false,
"start_date": "2025-12-24",
"completion_date": "2030-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06499870",
"publication_url": "https://clinicaltrials.gov/study/NCT06499870",
"title": "Optimizing Treatment and Advanced Multi-Imaging Response Evaluation for Very-High-Risk Prostate Cancer (OPTIMAL) - a Phase II Single Arm Study",
"has_exemption": false,
"start_date": "2024-09-06",
"completion_date": "2030-11-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Sean Sachdev",
"sponsor_slug": "sean-sachdev",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07050186",
"publication_url": "https://clinicaltrials.gov/study/NCT07050186",
"title": "A Single Arm Open-Label Pilot Study to Investigate the Safety and Clinical Activity of Cemiplimab, A Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients With Incurable NUT Carcinoma (NC)",
"has_exemption": false,
"start_date": "2025-08-15",
"completion_date": "2030-11-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06128070",
"publication_url": "https://clinicaltrials.gov/study/NCT06128070",
"title": "Phase 2a Study of Adding Ruxolitinib With Tacrolimus/Methotrexate Regimen for Graft-versus-Host Disease Prophylaxis in Myeloablative Conditioning Hematopoietic Cell Transplantation in Pediatric and Young Adult Patients",
"has_exemption": false,
"start_date": "2024-07-16",
"completion_date": "2030-11-22",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06211764",
"publication_url": "https://clinicaltrials.gov/study/NCT06211764",
"title": "A Phase 3, Randomized, Open-label, Multi-center Study Evaluating the Efficacy and Safety of TAR-200 Versus Investigator's Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High-risk Non-muscle-invasive Bladder Cancer (HR-NMIBC) and Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy",
"has_exemption": false,
"start_date": "2024-04-09",
"completion_date": "2030-11-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07489495",
"publication_url": "https://clinicaltrials.gov/study/NCT07489495",
"title": "A Phase 3, Randomized, Double-blind, Study of Belzutifan + Zanzalintinib Versus Belzutifan + Placebo in Participants With Advanced RCC Who Have Progressed on or After Both PD-1/L1 and VEGF-TKI Therapies in Sequence or in Combination (LITESPARK-034)",
"has_exemption": false,
"start_date": "2026-04-09",
"completion_date": "2030-11-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227597",
"publication_url": "https://clinicaltrials.gov/study/NCT07227597",
"title": "A Phase 1b/2 Open-label Study Evaluating Different MK-6070 and Ifinatamab Deruxtecan (MK-2400)-Based Regimens in First-line Extensive Stage Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-01-29",
"completion_date": "2030-11-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03587272",
"publication_url": "https://clinicaltrials.gov/study/NCT03587272",
"title": "Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2018-04-17",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Robert Nickel",
"sponsor_slug": "robert-nickel",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04927416",
"publication_url": "https://clinicaltrials.gov/study/NCT04927416",
"title": "The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer",
"has_exemption": false,
"start_date": "2021-10-25",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
"sponsor_slug": "national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06185673",
"publication_url": "https://clinicaltrials.gov/study/NCT06185673",
"title": "A Phase 1b/2a, Open-label, Dose Escalation Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia",
"has_exemption": false,
"start_date": "2023-11-28",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Benitec Biopharma, Inc.",
"sponsor_slug": "benitec-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06169371",
"publication_url": "https://clinicaltrials.gov/study/NCT06169371",
"title": "Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)",
"has_exemption": false,
"start_date": "2023-12-28",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06462547",
"publication_url": "https://clinicaltrials.gov/study/NCT06462547",
"title": "The ADAPT Study: An Open-label, Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency",
"has_exemption": false,
"start_date": "2024-06-19",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Inozyme Pharma",
"sponsor_slug": "inozyme-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06608927",
"publication_url": "https://clinicaltrials.gov/study/NCT06608927",
"title": "A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase 3 Trial of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Treatment-Naive Metastatic Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2024-12-13",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Arcus Biosciences, Inc.",
"sponsor_slug": "arcus-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06593093",
"publication_url": "https://clinicaltrials.gov/study/NCT06593093",
"title": "A Bundled Intervention to End Opioid Overdose by Increasing Treatment Uptake Post Emergency Department Discharge",
"has_exemption": false,
"start_date": "2025-02-13",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06671912",
"publication_url": "https://clinicaltrials.gov/study/NCT06671912",
"title": "LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients With Molecular Low-Risk Early-Stage Breast Cancer",
"has_exemption": false,
"start_date": "2025-02-19",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance for Clinical Trials in Oncology",
"sponsor_slug": "alliance-for-clinical-trials-in-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06649357",
"publication_url": "https://clinicaltrials.gov/study/NCT06649357",
"title": "Comparison Between Bipolar Transurethral Resection of the Prostate and Moses Assisted Holmium Laser Enucleation of the Prostate. A Prospective Randomized Multicentric Study",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fundacio Puigvert",
"sponsor_slug": "fundacio-puigvert",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06798909",
"publication_url": "https://clinicaltrials.gov/study/NCT06798909",
"title": "Kidney Transplant Preemptive Therapy or Prophylaxis (KPoP) for CMV Prevention in D+R- Recipients",
"has_exemption": false,
"start_date": "2025-07-22",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223424",
"publication_url": "https://clinicaltrials.gov/study/NCT07223424",
"title": "Patient Preference for Subcutaneous vs. Intravenous Immune Therapy (PSI-Immune)",
"has_exemption": false,
"start_date": "2025-11-04",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Diwakar Davar",
"sponsor_slug": "diwakar-davar",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227636",
"publication_url": "https://clinicaltrials.gov/study/NCT07227636",
"title": "Phase II Study of Adjuvant Botensilimab in Combination With Balstilimab in Patients With Colorectal Cancer and Persistent Circulating Tumor DNA Following Surgery and Chemotherapy",
"has_exemption": false,
"start_date": "2025-11-07",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07270991",
"publication_url": "https://clinicaltrials.gov/study/NCT07270991",
"title": "Randomized Phase III Trial to Compare Trifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Federation Francophone de Cancerologie Digestive",
"sponsor_slug": "federation-francophone-de-cancerologie-digestive",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220616",
"publication_url": "https://clinicaltrials.gov/study/NCT07220616",
"title": "A Phase 1/2, Multicenter, Open-Label, Multi-Cohort, First-in Human Trial of DS3790a, for Hematological Malignancies",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07194590",
"publication_url": "https://clinicaltrials.gov/study/NCT07194590",
"title": "Equol Supplementation for Improving Vascular Function in Postmenopausal Women With CKD",
"has_exemption": false,
"start_date": "2026-02-19",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07290738",
"publication_url": "https://clinicaltrials.gov/study/NCT07290738",
"title": "TMS for Negative Symptoms in Schizophrenia Spectrum Disorders",
"has_exemption": false,
"start_date": "2026-03-13",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298902",
"publication_url": "https://clinicaltrials.gov/study/NCT07298902",
"title": "Non-Invasive Deep Brain Neuromodulation for Smoking Cessation",
"has_exemption": false,
"start_date": "2026-03-15",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07559630",
"publication_url": "https://clinicaltrials.gov/study/NCT07559630",
"title": "STRATOS: Single-center Randomized Controlled Trial of Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS",
"has_exemption": false,
"start_date": "2026-05-29",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessica K. Stewart, MD",
"sponsor_slug": "jessica-k-stewart-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07560046",
"publication_url": "https://clinicaltrials.gov/study/NCT07560046",
"title": "Combating Related Epidemics in HCV Through Simplified Testing and Treatment. A Cluster Randomized Trial of Point-of-care Hepatitis C Testing and Treatment Among Key Populations",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2030-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05863351",
"publication_url": "https://clinicaltrials.gov/study/NCT05863351",
"title": "Phase III Randomized Trial of Stereotactic Ablative Radiotherapy (SAbR) for Oligometastatic Advanced Renal Carcinoma (SOAR)",
"has_exemption": false,
"start_date": "2023-09-07",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05616650",
"publication_url": "https://clinicaltrials.gov/study/NCT05616650",
"title": "A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer",
"has_exemption": false,
"start_date": "2023-10-19",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06569680",
"publication_url": "https://clinicaltrials.gov/study/NCT06569680",
"title": "Phase II Trial of Mosunetuzumab in Patients With Newly Diagnosed Extranodal Marginal Zone Lymphoma (EMZL) (ML44933)",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Izidore Lossos, MD",
"sponsor_slug": "izidore-lossos-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06540963",
"publication_url": "https://clinicaltrials.gov/study/NCT06540963",
"title": "Phase II Trial of Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Giselle Sholler",
"sponsor_slug": "giselle-sholler",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06640491",
"publication_url": "https://clinicaltrials.gov/study/NCT06640491",
"title": "Intraosseous Vancomycin and Cefazolin vs Intravenous Administration in Primary Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2025-05-15",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06124157",
"publication_url": "https://clinicaltrials.gov/study/NCT06124157",
"title": "An International Phase 2 Study of Chemotherapy and Tyrosine Kinase Inhibitors With Blinatumomab in Patients With Newly-Diagnosed Philadelphia Chromosome-Positive or ABL-Class Philadelphia Chromosome-Like B-Cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2025-05-30",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07210502",
"publication_url": "https://clinicaltrials.gov/study/NCT07210502",
"title": "Comparing the Side Effects of Low Dose Rate Brachytherapy Against Ultra-Hypofractionated Radiotherapy Using Spacer Gel Treatment in Men With Cambridge Prognostic Groups (CPG) 1 to 3 (NCCN Low to Intermediate Risk) Prostate Cancer",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Royal Surrey County Hospital NHS Foundation Trust",
"sponsor_slug": "royal-surrey-county-hospital-nhs-foundation-trust",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07439887",
"publication_url": "https://clinicaltrials.gov/study/NCT07439887",
"title": "Phase 1/2, Open-Label, Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease (AURORA)",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ray Therapeutics, Inc.",
"sponsor_slug": "ray-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07247097",
"publication_url": "https://clinicaltrials.gov/study/NCT07247097",
"title": "ELDORADO: a Randomized Phase II Trial of Elranatamab or Daratumumab in Combination With Lenalidomide, Bortezomib, and Dexamethasone (RVd Lite) in Newly Diagnosed, Transplant Ineligible/Deferred Multiple Myeloma",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07007221",
"publication_url": "https://clinicaltrials.gov/study/NCT07007221",
"title": "Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07593222",
"publication_url": "https://clinicaltrials.gov/study/NCT07593222",
"title": "Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mclean Hospital",
"sponsor_slug": "mclean-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07102524",
"publication_url": "https://clinicaltrials.gov/study/NCT07102524",
"title": "A Phase 1/2 Open-Label Intrathecal Administration of TSHA-105 to Determine the Safety and Efficacy in Subjects With SLC13A5 Citrate Transporter Disorder Caused by a Mutation in the SLC13A5 Gene.",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2030-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "TESS Research Foundation",
"sponsor_slug": "tess-research-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226232",
"publication_url": "https://clinicaltrials.gov/study/NCT07226232",
"title": "A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in Veterans",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2030-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225504",
"publication_url": "https://clinicaltrials.gov/study/NCT07225504",
"title": "A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of Remibrutinib in Patients With Secondary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-11-11",
"completion_date": "2030-12-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04557462",
"publication_url": "https://clinicaltrials.gov/study/NCT04557462",
"title": "A Multicenter Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan in Adult Participants With Primary IgA Nephropathy Who Have Completed Study CLNP023X2203 or CLNP023A2301",
"has_exemption": false,
"start_date": "2021-09-20",
"completion_date": "2030-12-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07583641",
"publication_url": "https://clinicaltrials.gov/study/NCT07583641",
"title": "A Global, Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult and Adolescent Participants With Autoimmune Encephalitis",
"has_exemption": false,
"start_date": "2026-07-13",
"completion_date": "2030-12-04",
"has_results": false,
"results_due": false,
"sponsor_name": "argenx",
"sponsor_slug": "argenx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06875973",
"publication_url": "https://clinicaltrials.gov/study/NCT06875973",
"title": "A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open-Label Pelacarsen in Participants With Elevated Lp(a) and Established ASCVD",
"has_exemption": false,
"start_date": "2025-05-19",
"completion_date": "2030-12-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594626",
"publication_url": "https://clinicaltrials.gov/study/NCT07594626",
"title": "A Phase Ib/II Basket Study of BMS-986504 in Combination With Pemetrexed for Metastatic Solid Tumors With MTAP Deletion",
"has_exemption": false,
"start_date": "2027-12-09",
"completion_date": "2030-12-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07639528",
"publication_url": "https://clinicaltrials.gov/study/NCT07639528",
"title": "Phase II, Open Label, Non-Randomized, Study of Optimal Preoperative Therapy for Intrahepatic Cholangiocarcinoma (OPTIC)",
"has_exemption": false,
"start_date": "2027-12-10",
"completion_date": "2030-12-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07064460",
"publication_url": "https://clinicaltrials.gov/study/NCT07064460",
"title": "Duke Customized Aortic Aneurysm Repair With Endovascular Stent-grafts - Duke CARES Trial",
"has_exemption": false,
"start_date": "2026-01-13",
"completion_date": "2030-12-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Chandler Long, MD",
"sponsor_slug": "chandler-long-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04929041",
"publication_url": "https://clinicaltrials.gov/study/NCT04929041",
"title": "A Randomized Phase II/III Trial of Modern Immunotherapy Based Systemic Therapy With or Without Radiation Therapy for PD-L1-Negative, Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2022-10-07",
"completion_date": "2030-12-12",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06923072",
"publication_url": "https://clinicaltrials.gov/study/NCT06923072",
"title": "A Phase IIa Trial of Baricitinib in the Treatment of Kohlmeier-Degos Disease Patients With Neurological Involvement",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2030-12-14",
"has_results": false,
"results_due": false,
"sponsor_name": "National Heart, Lung, and Blood Institute (NHLBI)",
"sponsor_slug": "national-heart-lung-and-blood-institute-nhlbi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03769415",
"publication_url": "https://clinicaltrials.gov/study/NCT03769415",
"title": "HARMONY: Harnessing the Analysis of RNA Expression and Molecular Subtype to Optimize Novel TherapY for Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2018-11-06",
"completion_date": "2030-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06753331",
"publication_url": "https://clinicaltrials.gov/study/NCT06753331",
"title": "A Multicenter, Sham-controlled, Randomized Study to Evaluate the Safety, Tolerability, and Clinical Responses Following Stereotactic Intracranial Implantation of DSP-1083 Into Subjects With Parkinson's Disease",
"has_exemption": false,
"start_date": "2024-12-18",
"completion_date": "2030-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Sumitomo Pharma America, Inc.",
"sponsor_slug": "sumitomo-pharma-america-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281456",
"publication_url": "https://clinicaltrials.gov/study/NCT07281456",
"title": "Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Disease Phase IIa Open-Label Clinical Trial and Associated Mechanistic Studies",
"has_exemption": false,
"start_date": "2025-12-18",
"completion_date": "2030-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Dental and Craniofacial Research (NIDCR)",
"sponsor_slug": "national-institute-of-dental-and-craniofacial-research-nidcr",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325604",
"publication_url": "https://clinicaltrials.gov/study/NCT07325604",
"title": "Effect of Neuromuscular Electrical Stimulation on Unilaterial Central Facial Palsy: An Assesorblinded Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-02-27",
"completion_date": "2030-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Aarhus",
"sponsor_slug": "university-of-aarhus",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07426484",
"publication_url": "https://clinicaltrials.gov/study/NCT07426484",
"title": "A Phase IV Master Protocol of Cosibelimab in Special Populations With Advanced Cutaneous Squamous Cell Carcinoma (CosiMaster)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06393374",
"publication_url": "https://clinicaltrials.gov/study/NCT06393374",
"title": "A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery",
"has_exemption": false,
"start_date": "2024-06-24",
"completion_date": "2030-12-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281417",
"publication_url": "https://clinicaltrials.gov/study/NCT07281417",
"title": "Neoadjuvant Chemotherapy With or Without Cemiplimab (REGN2810) in Sinonasal Squamous Cell Carcinoma: A Randomized Phase 2 Study",
"has_exemption": false,
"start_date": "2026-11-24",
"completion_date": "2030-12-16",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05431088",
"publication_url": "https://clinicaltrials.gov/study/NCT05431088",
"title": "A Phase 2/3 Randomized, Multicenter Study of Osivelotor Administered Orally to Adult and Adolescent Participants With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2022-09-22",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06482801",
"publication_url": "https://clinicaltrials.gov/study/NCT06482801",
"title": "Intra-tumor Delivery of Double Checkpoint Inhibitors, Chemodrug, and/or Bevacizumab Therapy as First Line for Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2024-06-10",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Second Affiliated Hospital of Guangzhou Medical University",
"sponsor_slug": "second-affiliated-hospital-of-guangzhou-medical-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06619509",
"publication_url": "https://clinicaltrials.gov/study/NCT06619509",
"title": "A Phase II, Single-arm, Open-label, Long-term Safety Rollover Trial of Oral Brigimadlin in Patients With Solid Tumours",
"has_exemption": false,
"start_date": "2024-12-30",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06332807",
"publication_url": "https://clinicaltrials.gov/study/NCT06332807",
"title": "An Open-Label, Multiple-Center, Phase I/II Dose Escalation Study for the Safety and Efficacy of NGGT002 in Adults With Classic Phenylketonuria",
"has_exemption": false,
"start_date": "2025-01-10",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NGGT INC.",
"sponsor_slug": "nggt-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609226",
"publication_url": "https://clinicaltrials.gov/study/NCT06609226",
"title": "An Open-label, Multi-centre, Rollover Study to Characterise Long-term Safety and Efficacy of Etavopivat in Adults, Adolescents and Children Who Have Sickle Cell Disease or Thalassaemia and Have Completed a Treatment Period in an Etavopivat Study",
"has_exemption": false,
"start_date": "2025-01-10",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06941272",
"publication_url": "https://clinicaltrials.gov/study/NCT06941272",
"title": "LIGHTBEAM-U01 Substudy 01C: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors",
"has_exemption": false,
"start_date": "2025-05-26",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07179939",
"publication_url": "https://clinicaltrials.gov/study/NCT07179939",
"title": "A Multicenter, Open-Label, Phase II Trial of Exploring the Maintenance of Trastuzumab Plus Pyrotinib or Trastuzumab Plus Dalpiciclib and Endocrine Therapy Based on HR Status Following Trastuzumab Rezetecan as Induction Treatment for HER2 Positive Unresectable Locally Recurrent or Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2025-09-10",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fudan University",
"sponsor_slug": "fudan-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07192952",
"publication_url": "https://clinicaltrials.gov/study/NCT07192952",
"title": "A Phase 3, Single-arm, Open-label Extension Study to Evaluate the Safety of Finerenone in Addition to Standard of Care, in Pediatric Heart Failure Patients, From Birth to 18 Years of Age, With Left Ventricular Systolic Dysfunction (LVSD)",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bayer",
"sponsor_slug": "bayer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07650240",
"publication_url": "https://clinicaltrials.gov/study/NCT07650240",
"title": "A Phase II Randomized Trial of Intermittent Androgen Deprivation Therapy Alone or Combined With [177Lu]Lu-PSMA-617, With or Without Abiraterone and Prednisone, in Patients With Low-Volume Metastatic Hormone-Sensitive Prostate Cancer",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07529405",
"publication_url": "https://clinicaltrials.gov/study/NCT07529405",
"title": "A Phase II Multi-center Randomized Clinical Trial to Determine the Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein (VG712) in Subjects With Mycosis Fungoides (CurbMF Trial)",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2030-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Virogen Biotechnology Inc.",
"sponsor_slug": "virogen-biotechnology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01042379",
"publication_url": "https://clinicaltrials.gov/study/NCT01042379",
"title": "I-SPY Trial (Investigation of Serial Studies to Predict Your Therapeutic Response With Imaging And moLecular Analysis 2)",
"has_exemption": false,
"start_date": "2010-03-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "QuantumLeap Healthcare Collaborative",
"sponsor_slug": "quantumleap-healthcare-collaborative",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01280994",
"publication_url": "https://clinicaltrials.gov/study/NCT01280994",
"title": "Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease",
"has_exemption": false,
"start_date": "2011-01-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bastiaan Driehuys",
"sponsor_slug": "bastiaan-driehuys",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01656603",
"publication_url": "https://clinicaltrials.gov/study/NCT01656603",
"title": "A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units Manufactured by the National Cord Blood Program and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients",
"has_exemption": false,
"start_date": "2012-02-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "New York Blood Center",
"sponsor_slug": "new-york-blood-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03915015",
"publication_url": "https://clinicaltrials.gov/study/NCT03915015",
"title": "VAPORHCS/OHSU J: Safety of Clinically Indicated Magnetic Resonance Imaging in Patients With Permanent Pacemakers (PPM) and Implanted Cardioverter Defibrillators (ICDs)",
"has_exemption": false,
"start_date": "2012-07-19",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oregon Health and Science University",
"sponsor_slug": "oregon-health-and-science-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01746836",
"publication_url": "https://clinicaltrials.gov/study/NCT01746836",
"title": "Ponatinib as Second Line Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phase Resistant or Intolerant to Imatinib, Dasatinib or Nilotinib",
"has_exemption": false,
"start_date": "2013-01-17",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02079662",
"publication_url": "https://clinicaltrials.gov/study/NCT02079662",
"title": "Integrative Oncology Program in Improving Cancer-Related Outcomes in Patients With Stage II or III Breast Cancer Undergoing Radiation Therapy",
"has_exemption": false,
"start_date": "2013-06-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02019706",
"publication_url": "https://clinicaltrials.gov/study/NCT02019706",
"title": "Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome",
"has_exemption": false,
"start_date": "2014-02-12",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
"sponsor_slug": "national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02875314",
"publication_url": "https://clinicaltrials.gov/study/NCT02875314",
"title": "HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors Clinical and Molecular Risk-Tailored Intensive and Compressed Induction Chemotherapy Followed by Consolidation With Randomization to Either Single Cycle or to Three Tandem Cycles of Marrow-Ablative Chemotherapy With Autologous Hematopoietic Progenitor Cell Rescue",
"has_exemption": false,
"start_date": "2015-09-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Parth Patel",
"sponsor_slug": "parth-patel",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03096743",
"publication_url": "https://clinicaltrials.gov/study/NCT03096743",
"title": "Evaluating Raised Intracranial Pressure Using MR Elastography",
"has_exemption": false,
"start_date": "2017-01-10",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03868150",
"publication_url": "https://clinicaltrials.gov/study/NCT03868150",
"title": "Assessment of Intra-Operative Atrial Fibrillation Inducibility As a Screening Tool to Prevent Post-Operative Atrial Fibrillation With Prophylaxis Amiodarone",
"has_exemption": false,
"start_date": "2017-03-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03138161",
"publication_url": "https://clinicaltrials.gov/study/NCT03138161",
"title": "SAINT: A Phase 1/2 Study of Safe Amounts of IPLIMUMAB, NIVOLUMAB and TRABECTEDIN for Previously Treated Advanced Soft Tissue Sarcoma (STS)",
"has_exemption": false,
"start_date": "2017-04-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarcoma Oncology Research Center, LLC",
"sponsor_slug": "sarcoma-oncology-research-center-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00583817",
"publication_url": "https://clinicaltrials.gov/study/NCT00583817",
"title": "Endovascular Treatment of Thoracic Aortic Disease",
"has_exemption": false,
"start_date": "2018-10-25",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Matthew Eagleton",
"sponsor_slug": "matthew-eagleton",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03935685",
"publication_url": "https://clinicaltrials.gov/study/NCT03935685",
"title": "Pilot Study of Mirtazapine for the Dual Treatment of Depression and Temozolomide-Induced Nausea and Vomiting (CINV) in Newly-Diagnosed High-Grade Glioma Patients on Temozolomide Therapy",
"has_exemption": false,
"start_date": "2019-02-26",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Irvine",
"sponsor_slug": "university-of-california-irvine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03886311",
"publication_url": "https://clinicaltrials.gov/study/NCT03886311",
"title": "The TNT Protocol: A Phase 2 Study Using Talimogene Laherparepvec,Nivolumab and Trabectedin as First, Second/Third Line Therapy for Advanced Sarcoma, Including Desmoid Tumor and Chordoma",
"has_exemption": false,
"start_date": "2019-05-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarcoma Oncology Research Center, LLC",
"sponsor_slug": "sarcoma-oncology-research-center-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04127578",
"publication_url": "https://clinicaltrials.gov/study/NCT04127578",
"title": "A Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)",
"has_exemption": false,
"start_date": "2020-01-03",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prevail Therapeutics",
"sponsor_slug": "prevail-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04106466",
"publication_url": "https://clinicaltrials.gov/study/NCT04106466",
"title": "Deep Brain Stimulation (DBS) for Treatment Resistant Depression: Exploration of Local Field Potentials (LFPs) With the Medtronic Summit RC+S \"Brain Radio\" System",
"has_exemption": false,
"start_date": "2020-01-21",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Helen Mayberg, MD",
"sponsor_slug": "helen-mayberg-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04166409",
"publication_url": "https://clinicaltrials.gov/study/NCT04166409",
"title": "A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine Versus Selumetinib (NSC# 748727) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) Not Associated With BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)",
"has_exemption": false,
"start_date": "2020-01-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04371913",
"publication_url": "https://clinicaltrials.gov/study/NCT04371913",
"title": "Personalized Second Chance Breast Conservation (PSCBC): A Two Center Prospective Phase II Clinical Study",
"has_exemption": false,
"start_date": "2020-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04629469",
"publication_url": "https://clinicaltrials.gov/study/NCT04629469",
"title": "Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients",
"has_exemption": false,
"start_date": "2020-10-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Mercy Hospital Kansas City",
"sponsor_slug": "childrens-mercy-hospital-kansas-city",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04729933",
"publication_url": "https://clinicaltrials.gov/study/NCT04729933",
"title": "Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip: The V-Wave Shunt MitraClip Study",
"has_exemption": false,
"start_date": "2021-03-11",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Samir Kapadia",
"sponsor_slug": "samir-kapadia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04747626",
"publication_url": "https://clinicaltrials.gov/study/NCT04747626",
"title": "B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair",
"has_exemption": false,
"start_date": "2021-03-25",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eric Roselli, M. D.",
"sponsor_slug": "eric-roselli-m-d",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04511078",
"publication_url": "https://clinicaltrials.gov/study/NCT04511078",
"title": "Phase II Open-Label Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Head and Neck Cancer During Surgical Procedures",
"has_exemption": false,
"start_date": "2021-04-02",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04614103",
"publication_url": "https://clinicaltrials.gov/study/NCT04614103",
"title": "A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (TIL or LN-145) in Patients With Metastatic Non-Small-Cell Lung Cancer",
"has_exemption": false,
"start_date": "2021-05-07",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Iovance Biotherapeutics, Inc.",
"sponsor_slug": "iovance-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04844606",
"publication_url": "https://clinicaltrials.gov/study/NCT04844606",
"title": "A Master Protocol for a Phase 3, Multicenter, Open-label, Long-term Extension Study to Evaluate the Long-term Efficacy and Safety of Mirikizumab in Children and Adolescents With Moderate-to-severe Ulcerative Colitis or Crohn's Disease",
"has_exemption": false,
"start_date": "2021-05-26",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07056348",
"publication_url": "https://clinicaltrials.gov/study/NCT07056348",
"title": "Chronic Stimulation of the Motor Ventral Thalamus (VOP/VIM) for Motor Control in Humans",
"has_exemption": false,
"start_date": "2022-05-10",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jorge Gonzalez-Martinez",
"sponsor_slug": "jorge-gonzalez-martinez",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06654180",
"publication_url": "https://clinicaltrials.gov/study/NCT06654180",
"title": "A Comparison of Myopia Control Efficacy in Children With Orthokeratology, Defocus Incorporated Multiple Segment (DIMS) Spectacles, Defocus Incorporated Soft Contact (DISK) Lenses, and Single-vision Spectacles for 12 Months",
"has_exemption": false,
"start_date": "2022-10-21",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kaikai QIU",
"sponsor_slug": "kaikai-qiu",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05344833",
"publication_url": "https://clinicaltrials.gov/study/NCT05344833",
"title": "Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma",
"has_exemption": false,
"start_date": "2023-01-05",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05910528",
"publication_url": "https://clinicaltrials.gov/study/NCT05910528",
"title": "A Phase 2, Multicenter, Double-blind, Two-arm Study of Subcutaneous RO7790121 for the Treatment of Subjects With Moderate to Severe Active Crohn's Disease",
"has_exemption": false,
"start_date": "2023-07-24",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06134167",
"publication_url": "https://clinicaltrials.gov/study/NCT06134167",
"title": "A Prospective, Multicenter, Single-Arm, Open-Label Study to Evaluate the Safety and Effectiveness of the Transdermal Compress Device in Participants With Transfemoral Amputations",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Balmoral Medical company",
"sponsor_slug": "balmoral-medical-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06877312",
"publication_url": "https://clinicaltrials.gov/study/NCT06877312",
"title": "Longitudinal Study to Investigate Different Treatment Protocols of Transcranial Electrical Stimulation for Individuals With Dementia",
"has_exemption": false,
"start_date": "2024-10-09",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Manitoba",
"sponsor_slug": "university-of-manitoba",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06713616",
"publication_url": "https://clinicaltrials.gov/study/NCT06713616",
"title": "Comparative Effectiveness of Racemic Ketamine Versus Esketamine (Spravato®) for Depression",
"has_exemption": false,
"start_date": "2025-01-27",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06657794",
"publication_url": "https://clinicaltrials.gov/study/NCT06657794",
"title": "Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms",
"has_exemption": false,
"start_date": "2025-02-17",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06960707",
"publication_url": "https://clinicaltrials.gov/study/NCT06960707",
"title": "Prospective Randomized Trial of Two Versus One Week Accelerated Radiotherapy (PRATO)",
"has_exemption": false,
"start_date": "2025-04-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06655051",
"publication_url": "https://clinicaltrials.gov/study/NCT06655051",
"title": "Efficacy and Safety of Single Plastic Stent Compared With Fully Covered Self-Expanding Metal Stent on Benign Biliary Stricture Secondary to Chronic Pancreatitis: A Single Center,Prospective,Non-inferiority, Open Label, Randomized, Controlled Trial",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Changhai Hospital",
"sponsor_slug": "changhai-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07050043",
"publication_url": "https://clinicaltrials.gov/study/NCT07050043",
"title": "A Phase III RCT Comparing Low Dose Immunotherapy (Nivolumab) Combined With Standard Chemotherapy vs Standard Chemotherapy as First-line Treatment in Patients With Locally Advanced or Metastatic NSCLC",
"has_exemption": false,
"start_date": "2025-05-19",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dr Arvindran A/L Alaga",
"sponsor_slug": "dr-arvindran-al-alaga",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07148739",
"publication_url": "https://clinicaltrials.gov/study/NCT07148739",
"title": "Ensuring Access to Optimal Therapy in Cystic Fibrosis: The ENACT Study",
"has_exemption": false,
"start_date": "2025-06-10",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arkansas Children's Hospital Research Institute",
"sponsor_slug": "arkansas-childrens-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06568549",
"publication_url": "https://clinicaltrials.gov/study/NCT06568549",
"title": "Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf® Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.",
"has_exemption": false,
"start_date": "2025-06-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07079631",
"publication_url": "https://clinicaltrials.gov/study/NCT07079631",
"title": "A Phase I/II, Randomized, Multi-site Trial to Investigate the Efficacy and Safety of BNT314 in Combination With BNT327 and Chemotherapy in Participants With Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-07-18",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953960",
"publication_url": "https://clinicaltrials.gov/study/NCT06953960",
"title": "A Phase 1/2, Open-Label, Platform Study to Evaluate Safety and Efficacy of the BCL-2 Inhibitor Surzetoclax (ABBV-453) Given as Monotherapy or in Combination With Antimyeloma Regimens in Subjects With Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-07-23",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06381180",
"publication_url": "https://clinicaltrials.gov/study/NCT06381180",
"title": "Wayne Warrior CAnnabis Research and Education: Cannabis and Behavioral Health",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wayne State University",
"sponsor_slug": "wayne-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158606",
"publication_url": "https://clinicaltrials.gov/study/NCT07158606",
"title": "Understanding Treatment Outcomes and Immunologic Mechanisms in ALtuviiio Immune Tolerance Induction",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Versiti Blood Health",
"sponsor_slug": "versiti-blood-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07213934",
"publication_url": "https://clinicaltrials.gov/study/NCT07213934",
"title": "WOPPPR: Window of Opportunity Phase I and Phase II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-10-08",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Cincinnati",
"sponsor_slug": "university-of-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06934356",
"publication_url": "https://clinicaltrials.gov/study/NCT06934356",
"title": "Shared Subcortical Arousal Systems Across Perceptual Modalities",
"has_exemption": false,
"start_date": "2025-10-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227532",
"publication_url": "https://clinicaltrials.gov/study/NCT07227532",
"title": "Assessment of Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the VARIPULSE™ Catheter System",
"has_exemption": false,
"start_date": "2025-10-21",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biosense Webster, Inc.",
"sponsor_slug": "biosense-webster-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07061977",
"publication_url": "https://clinicaltrials.gov/study/NCT07061977",
"title": "NRG-GY037: A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab Versus Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer",
"has_exemption": false,
"start_date": "2025-11-05",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07196644",
"publication_url": "https://clinicaltrials.gov/study/NCT07196644",
"title": "A Phase 2 Study to Evaluate the Safety and Efficacy of Telisotuzumab Adizutecan for the Treatment of Subjects With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06991101",
"publication_url": "https://clinicaltrials.gov/study/NCT06991101",
"title": "Randomized Phase 2 Trial of Ruxolitinib in Combination With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma.",
"has_exemption": false,
"start_date": "2025-12-03",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Baptist Health South Florida",
"sponsor_slug": "baptist-health-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06963905",
"publication_url": "https://clinicaltrials.gov/study/NCT06963905",
"title": "Phase Ib Randomized Open-label Trial of Sacituzumab Govitecan Plus Nivolumab or Sacituzumab Govitecan Plus Nivolumab and Relatlimab as Second-line Therapy for Patients With Metastatic Triple Negative Breast Cancer",
"has_exemption": false,
"start_date": "2025-12-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219199",
"publication_url": "https://clinicaltrials.gov/study/NCT07219199",
"title": "Intraoperative Quantification of Residual IDH1-mutant Tumor Cells Via Ultra-Rapid Droplet Digital PCR",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07276386",
"publication_url": "https://clinicaltrials.gov/study/NCT07276386",
"title": "Phase 2 Sequential Treatment With Melphalan/HDS Via Percutaneous Hepatic Perfusion Followed by Tebentafusp in the Treatment of Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318493",
"publication_url": "https://clinicaltrials.gov/study/NCT07318493",
"title": "Does Antiseptic Coated Suture Reduce Pancreatic Fistula Rate After Pancreatoduodenectomy: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-01-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06417190",
"publication_url": "https://clinicaltrials.gov/study/NCT06417190",
"title": "IIT2023-13-BALLAS-VHTMT: Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Leslie Ballas",
"sponsor_slug": "leslie-ballas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07091396",
"publication_url": "https://clinicaltrials.gov/study/NCT07091396",
"title": "Enhancing Functional Recovery With Home-based Transcranial Direct Current Stimulation (tDCS) in Patients With Stroke, Neurodegeneration and Brain Tumors",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222046",
"publication_url": "https://clinicaltrials.gov/study/NCT07222046",
"title": "Identifying Residual Connectivity in Veterans With Spinal Cord Injury for Precision Neurorehabilitation",
"has_exemption": false,
"start_date": "2026-01-23",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07478172",
"publication_url": "https://clinicaltrials.gov/study/NCT07478172",
"title": "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults withNeuromuscular Disease",
"has_exemption": false,
"start_date": "2026-03-10",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Missouri-Columbia",
"sponsor_slug": "university-of-missouri-columbia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07118618",
"publication_url": "https://clinicaltrials.gov/study/NCT07118618",
"title": "Probenecid, Pannexin 1 Channels for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-03-14",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brown University",
"sponsor_slug": "brown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07361549",
"publication_url": "https://clinicaltrials.gov/study/NCT07361549",
"title": "Localized Injection of Lidocaine Via the Middle Meningeal Artery for Intractable Headache Treatment: A Randomized, Double-Blinded, Parallel Phase 2 Clinical Trial",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daniel A Tonetti, MD",
"sponsor_slug": "daniel-a-tonetti-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07434726",
"publication_url": "https://clinicaltrials.gov/study/NCT07434726",
"title": "CPReboa: In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta",
"has_exemption": false,
"start_date": "2026-04-14",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Insel Gruppe AG, University Hospital Bern",
"sponsor_slug": "insel-gruppe-ag-university-hospital-bern",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07230990",
"publication_url": "https://clinicaltrials.gov/study/NCT07230990",
"title": "Mechanisms Of Orbitofrontal Stimulation in Depression (MOOD)",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Subha Subramanian",
"sponsor_slug": "subha-subramanian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07495995",
"publication_url": "https://clinicaltrials.gov/study/NCT07495995",
"title": "A Single-center, Phase II Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Effect of S-adenosyl-L-methionine (SAMe) in Prevention of Hepatocellular Carcinoma Among Patients With Metabolic Dysfunction-associated Steatotic Liver Diseases (MASLD)-Related Cirrhosis",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07531745",
"publication_url": "https://clinicaltrials.gov/study/NCT07531745",
"title": "Phase 1-2, Open-Label, Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION337 in Patients With Dravet Syndrome",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07043738",
"publication_url": "https://clinicaltrials.gov/study/NCT07043738",
"title": "Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07483255",
"publication_url": "https://clinicaltrials.gov/study/NCT07483255",
"title": "A Phase II Trial of Fetal Embolization for Vein of Galen Malformation",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Darren Orbach",
"sponsor_slug": "darren-orbach",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594652",
"publication_url": "https://clinicaltrials.gov/study/NCT07594652",
"title": "USE of JORNAY PM® to TREAT ADHD in PEDIATRIC EPILEPSY",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hugo W. Moser Research Institute at Kennedy Krieger, Inc.",
"sponsor_slug": "hugo-w-moser-research-institute-at-kennedy-krieger-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07283497",
"publication_url": "https://clinicaltrials.gov/study/NCT07283497",
"title": "Itraconazole Therapy In Bronchiectasis With Airway Mold: A Single-Arm Pilot Trial Of Feasibility, Safety, And Impact On Respiratory Symptoms And Airway Microbiome Diversity",
"has_exemption": false,
"start_date": "2026-06-20",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07416188",
"publication_url": "https://clinicaltrials.gov/study/NCT07416188",
"title": "Phase 1/Phase 2 Open Label Trial of a Novel Indenoisoquinolone C-MYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2026-06-22",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Neurological Disorders and Stroke (NINDS)",
"sponsor_slug": "national-institute-of-neurological-disorders-and-stroke-ninds",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07504601",
"publication_url": "https://clinicaltrials.gov/study/NCT07504601",
"title": "Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers",
"has_exemption": false,
"start_date": "2026-06-22",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Center for Complementary and Integrative Health (NCCIH)",
"sponsor_slug": "national-center-for-complementary-and-integrative-health-nccih",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07101666",
"publication_url": "https://clinicaltrials.gov/study/NCT07101666",
"title": "Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281924",
"publication_url": "https://clinicaltrials.gov/study/NCT07281924",
"title": "A Phase 1b/2 Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of Melphalan Percutaneous Hepatic Perfusion Therapy (HEPZATO KIT™) With Nivolumab and Relatlimab (Opdualag) in Patients With Metastatic Melanoma and Liver Metastasis",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07608432",
"publication_url": "https://clinicaltrials.gov/study/NCT07608432",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of DYNE-251 Administered Intravenously in Ambulatory Male Participants 4 to 18 Years of Age With Duchenne Muscular Dystrophy Amenable to Exon-51 Skipping",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dyne Therapeutics",
"sponsor_slug": "dyne-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07398404",
"publication_url": "https://clinicaltrials.gov/study/NCT07398404",
"title": "A Multiple Health Behavior Change Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07628062",
"publication_url": "https://clinicaltrials.gov/study/NCT07628062",
"title": "Open-Label, Single-Arm Phase 2 Study Of Nogapendekin Alfa Inbakicept, PD-L1 T-HaNK, And Bevacizumab And Randomized Phase 2B Study Of Nogapendekin Alfa Inbakicept, Bevacizumab, And Tumor Treatment Fields With Or Without PD-L1 T-HaNK In Participants With Recurrent Or Progressive Glioblastoma",
"has_exemption": false,
"start_date": "2026-07-22",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ImmunityBio, Inc.",
"sponsor_slug": "immunitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06683534",
"publication_url": "https://clinicaltrials.gov/study/NCT06683534",
"title": "Use of Quercetin to Increase Resiliency to Palmitic Acid in the Human Microvasculature",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04172779",
"publication_url": "https://clinicaltrials.gov/study/NCT04172779",
"title": "Phase II Clinical Trial of Low-dose Erlotinib for Hepatocellular Carcinoma Chemoprevention",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07261150",
"publication_url": "https://clinicaltrials.gov/study/NCT07261150",
"title": "Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)",
"has_exemption": false,
"start_date": "2026-09-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07607860",
"publication_url": "https://clinicaltrials.gov/study/NCT07607860",
"title": "Feasibility Clinical Evaluation of the Adaptilens Accommodating IOL",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Adaptilens, Inc.",
"sponsor_slug": "adaptilens-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07551583",
"publication_url": "https://clinicaltrials.gov/study/NCT07551583",
"title": "A Phase 2 Single Arm Study To Evaluate Safety And Preliminary Efficacy Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With Newly Diagnosed Early-Stage Non-Bulky Classical Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07654426",
"publication_url": "https://clinicaltrials.gov/study/NCT07654426",
"title": "A Randomized Study of Dexrazoxane or Liposomal Doxorubicin in Newly Diagnosed Diffuse Large B-cell Lymphoma at High Risk for Heart Failure Events: the CARDIOPROTECT Trial",
"has_exemption": false,
"start_date": "2026-10-02",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07649070",
"publication_url": "https://clinicaltrials.gov/study/NCT07649070",
"title": "Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07477418",
"publication_url": "https://clinicaltrials.gov/study/NCT07477418",
"title": "PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP): A Phase Ib/II Open-Label Trial",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Vermont",
"sponsor_slug": "university-of-vermont",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07359872",
"publication_url": "https://clinicaltrials.gov/study/NCT07359872",
"title": "Relaxin Therapy for Atrial Fibrillation",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Deeptankar DeMazumder",
"sponsor_slug": "deeptankar-demazumder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06454110",
"publication_url": "https://clinicaltrials.gov/study/NCT06454110",
"title": "A Phase II, Open-Label Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)",
"has_exemption": false,
"start_date": "2028-02-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06318403",
"publication_url": "https://clinicaltrials.gov/study/NCT06318403",
"title": "Estradiol Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial",
"has_exemption": false,
"start_date": "2028-03-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05968326",
"publication_url": "https://clinicaltrials.gov/study/NCT05968326",
"title": "A Phase II, Open-Label, Multicenter, Randomized Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Patients With Resected Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2023-10-18",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06179472",
"publication_url": "https://clinicaltrials.gov/study/NCT06179472",
"title": "Infant Survival and Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial",
"has_exemption": false,
"start_date": "2024-04-14",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Inna Lobeck",
"sponsor_slug": "inna-lobeck",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07304011",
"publication_url": "https://clinicaltrials.gov/study/NCT07304011",
"title": "A Phase 2 Study of Olutasidenib in Combination With Azacitidine Followed by Olutasidenib Maintenance After Venetoclax Plus a Hypomethylating Agent Regimen (HMA-VEN) for IDH1-Mutated Acute Myeloid Leukemia (AML)",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228104",
"publication_url": "https://clinicaltrials.gov/study/NCT07228104",
"title": "Adjuvant STeRoid Outcomes in Idiopathic Subglottic Stenosis",
"has_exemption": false,
"start_date": "2026-05-20",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07499583",
"publication_url": "https://clinicaltrials.gov/study/NCT07499583",
"title": "Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06919939",
"publication_url": "https://clinicaltrials.gov/study/NCT06919939",
"title": "Phase 2 Study of Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2026-01-07",
"completion_date": "2031-01-07",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07082842",
"publication_url": "https://clinicaltrials.gov/study/NCT07082842",
"title": "A Multicenter, Parallel, Randomized, Placebo (Double-blind) and Pirfenidone (Open-label) Controlled Phase III Clinical Trial Evaluating the Efficacy and Safety of HEC585 Tablets in Patients With Idiopathic Pulmonary Fibrosis (IPF)",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2031-01-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Sunshine Lake Pharma Co., Ltd.",
"sponsor_slug": "sunshine-lake-pharma-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07116967",
"publication_url": "https://clinicaltrials.gov/study/NCT07116967",
"title": "A Phase 3b/4 Multi-center, Randomized, Open-label, Long-term Safety Study of Deucravacitinib in Comparison to Ustekinumab in Participants With Moderate-to-Severe Plaque Psoriasis",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2031-01-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06615050",
"publication_url": "https://clinicaltrials.gov/study/NCT06615050",
"title": "A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2025-04-02",
"completion_date": "2031-01-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Incyte Corporation",
"sponsor_slug": "incyte-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609239",
"publication_url": "https://clinicaltrials.gov/study/NCT06609239",
"title": "An Open Label Extension Study to Evaluate the Long-term Safety and Efficacy of Subcutaneous Lunsekimig in Adult Participants With Asthma Who Participated in Study DRI16762 or ACT18301",
"has_exemption": false,
"start_date": "2024-09-30",
"completion_date": "2031-01-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07234032",
"publication_url": "https://clinicaltrials.gov/study/NCT07234032",
"title": "A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2031-01-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Insmed Incorporated",
"sponsor_slug": "insmed-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07465289",
"publication_url": "https://clinicaltrials.gov/study/NCT07465289",
"title": "A Phase 3, Open-Label, Extension Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis",
"has_exemption": false,
"start_date": "2026-07-27",
"completion_date": "2031-01-23",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03725059",
"publication_url": "https://clinicaltrials.gov/study/NCT03725059",
"title": "A Randomized, Double-Blind, Phase III Study of Pembrolizumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy for the Treatment of High-Risk Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (KEYNOTE-756)",
"has_exemption": false,
"start_date": "2018-12-27",
"completion_date": "2031-01-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06667700",
"publication_url": "https://clinicaltrials.gov/study/NCT06667700",
"title": "A Phase 3, Randomized, Placebo-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adults With COVID-19 at High Risk for Disease Progression",
"has_exemption": false,
"start_date": "2024-12-02",
"completion_date": "2031-01-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06914908",
"publication_url": "https://clinicaltrials.gov/study/NCT06914908",
"title": "A Single-arm Extension Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2031-01-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03076658",
"publication_url": "https://clinicaltrials.gov/study/NCT03076658",
"title": "Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers",
"has_exemption": false,
"start_date": "2016-09-30",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06185205",
"publication_url": "https://clinicaltrials.gov/study/NCT06185205",
"title": "Accelerated Super-Hypofractionated Breast Brachytherapy - ASHBY Trial",
"has_exemption": false,
"start_date": "2023-12-12",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06313203",
"publication_url": "https://clinicaltrials.gov/study/NCT06313203",
"title": "Trans-arterial Treatment of Patients With Intra-hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)",
"has_exemption": false,
"start_date": "2024-02-13",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oslo University Hospital",
"sponsor_slug": "oslo-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06543576",
"publication_url": "https://clinicaltrials.gov/study/NCT06543576",
"title": "A Prospective Cohort Study of Integrating Radiotherapy Into Chemotherapy With Pembrolizumab and Bevacizumab in Newly Diagnosed Stage IVB Cervical Cancer",
"has_exemption": false,
"start_date": "2025-07-29",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07059091",
"publication_url": "https://clinicaltrials.gov/study/NCT07059091",
"title": "Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD (COPD-OMA)",
"has_exemption": false,
"start_date": "2026-02-12",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318883",
"publication_url": "https://clinicaltrials.gov/study/NCT07318883",
"title": "A Randomized, Double-Blind, Multicenter, Phase II/III Clinical Study to Evaluate HLX07 (Recombinant Anti-EGFR Humanized Monoclonal Antibody Injection) in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Patients With Advanced Squamous Non-Small Cell Lung Cancer (sqNSCLC)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Henlius Biotech",
"sponsor_slug": "shanghai-henlius-biotech",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288112",
"publication_url": "https://clinicaltrials.gov/study/NCT07288112",
"title": "Clinical Study of DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Diakonos Oncology Corporation",
"sponsor_slug": "diakonos-oncology-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226739",
"publication_url": "https://clinicaltrials.gov/study/NCT07226739",
"title": "Comprehensive Toileting Programming: Enuresis Treatment to a Randomized Clinical Trial of a Caregiver-Mediated Multidisciplinary Intervention for Encopresis",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03181867",
"publication_url": "https://clinicaltrials.gov/study/NCT03181867",
"title": "18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer",
"has_exemption": false,
"start_date": "2017-08-03",
"completion_date": "2031-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07527338",
"publication_url": "https://clinicaltrials.gov/study/NCT07527338",
"title": "Mechanisms of Cannabidiol and Sleep in the Context of Alcohol Use",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2031-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Boulder",
"sponsor_slug": "university-of-colorado-boulder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07493317",
"publication_url": "https://clinicaltrials.gov/study/NCT07493317",
"title": "Neutralizing Interleukin (IL)-6 Signaling to Reverse Immune Related Anhedonia in Patients With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2026-03-26",
"completion_date": "2031-02-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06312722",
"publication_url": "https://clinicaltrials.gov/study/NCT06312722",
"title": "Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study",
"has_exemption": false,
"start_date": "2024-02-07",
"completion_date": "2031-02-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Urotronic Inc.",
"sponsor_slug": "urotronic-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06401330",
"publication_url": "https://clinicaltrials.gov/study/NCT06401330",
"title": "Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2031-02-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03418038",
"publication_url": "https://clinicaltrials.gov/study/NCT03418038",
"title": "Phase2 Trial of High Dose Intravenous Ascorbic Acid as an Adjunct to Salvage Chemotherapy in Relapsed/ Refractory Lymphoma, Patients With Clonal Cytopenia of Undetermined Significance, and Chronic Myelomonocytic Leukemia",
"has_exemption": false,
"start_date": "2018-03-23",
"completion_date": "2031-02-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07178808",
"publication_url": "https://clinicaltrials.gov/study/NCT07178808",
"title": "PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER",
"has_exemption": false,
"start_date": "2021-04-16",
"completion_date": "2031-02-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Banner Health",
"sponsor_slug": "banner-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06618287",
"publication_url": "https://clinicaltrials.gov/study/NCT06618287",
"title": "A Phase 1/2a, Open-label, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BMS-986507 (BL-B01D1) Combinations in Adult Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-02-04",
"completion_date": "2031-02-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04251026",
"publication_url": "https://clinicaltrials.gov/study/NCT04251026",
"title": "A Phase 1/2, Multicenter, Open-Label Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL310 in Pediatric Participants With Hunter Syndrome",
"has_exemption": false,
"start_date": "2020-07-16",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06066580",
"publication_url": "https://clinicaltrials.gov/study/NCT06066580",
"title": "An Open-Label Extension Study to Assess the Long-term Effect of EDG-5506 on Safety, Biomarkers, and Functional Measures in Adults and Adolescents With Becker Muscular Dystrophy",
"has_exemption": false,
"start_date": "2023-11-02",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Edgewise Therapeutics, Inc.",
"sponsor_slug": "edgewise-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06302348",
"publication_url": "https://clinicaltrials.gov/study/NCT06302348",
"title": "A Phase 3b Open-Label Study of Long-Term Neurocognitive Outcomes in Children With Phenylketonuria Treated With Sepiapterin",
"has_exemption": false,
"start_date": "2024-03-04",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "PTC Therapeutics",
"sponsor_slug": "ptc-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06378866",
"publication_url": "https://clinicaltrials.gov/study/NCT06378866",
"title": "MC230502 Dynamic Investigator Initiated Enterprise (DIVINE) in Prostate Cancer",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06575192",
"publication_url": "https://clinicaltrials.gov/study/NCT06575192",
"title": "A Prospective, Multicenter, Open-Label, Non-Randomized, Controlled Pivotal Study to Evaluate the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix in Implant-Based Two Stage Prepectoral Breast Reconstruction Post-Mastectomy",
"has_exemption": false,
"start_date": "2024-11-05",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07277231",
"publication_url": "https://clinicaltrials.gov/study/NCT07277231",
"title": "A Phase 3, Open-Label, Randomized Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Patients With Previously Untreated Chronic Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2026-01-22",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07136415",
"publication_url": "https://clinicaltrials.gov/study/NCT07136415",
"title": "CELESTE: Comparative Effectiveness Study of behavioraL and Drug-rElated inSomnia Therapies for pEri- and Post-menopausal People",
"has_exemption": false,
"start_date": "2026-02-13",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222631",
"publication_url": "https://clinicaltrials.gov/study/NCT07222631",
"title": "An Open-Label, First-in-Human Phase 1/2, Dose-Escalation and Dose-Expansion/ Combination Therapy Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SB-4826 as a Single Agent in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas and in Combination With Rituximab in Adult Participants With Non-Hodgkin Lymphomas",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}