HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 49668,
"recordsTotal": 49668,
"next": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=registry_id&start=49200",
"previous": "http://staging-fdaaa.ebmdatalab.net/api/trials/?format=api&length=300&ordering=registry_id&start=48600",
"results": [
{
"registry_id": "NCT07276386",
"publication_url": "https://clinicaltrials.gov/study/NCT07276386",
"title": "Phase 2 Sequential Treatment With Melphalan/HDS Via Percutaneous Hepatic Perfusion Followed by Tebentafusp in the Treatment of Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318493",
"publication_url": "https://clinicaltrials.gov/study/NCT07318493",
"title": "Does Antiseptic Coated Suture Reduce Pancreatic Fistula Rate After Pancreatoduodenectomy: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-01-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06417190",
"publication_url": "https://clinicaltrials.gov/study/NCT06417190",
"title": "IIT2023-13-BALLAS-VHTMT: Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Leslie Ballas",
"sponsor_slug": "leslie-ballas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07091396",
"publication_url": "https://clinicaltrials.gov/study/NCT07091396",
"title": "Enhancing Functional Recovery With Home-based Transcranial Direct Current Stimulation (tDCS) in Patients With Stroke, Neurodegeneration and Brain Tumors",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07478172",
"publication_url": "https://clinicaltrials.gov/study/NCT07478172",
"title": "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults withNeuromuscular Disease",
"has_exemption": false,
"start_date": "2026-03-10",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Missouri-Columbia",
"sponsor_slug": "university-of-missouri-columbia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07118618",
"publication_url": "https://clinicaltrials.gov/study/NCT07118618",
"title": "Probenecid, Pannexin 1 Channels for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-03-14",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brown University",
"sponsor_slug": "brown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07361549",
"publication_url": "https://clinicaltrials.gov/study/NCT07361549",
"title": "Localized Injection of Lidocaine Via the Middle Meningeal Artery for Intractable Headache Treatment: A Randomized, Double-Blinded, Parallel Phase 2 Clinical Trial",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daniel A Tonetti, MD",
"sponsor_slug": "daniel-a-tonetti-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07434726",
"publication_url": "https://clinicaltrials.gov/study/NCT07434726",
"title": "CPReboa: In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta",
"has_exemption": false,
"start_date": "2026-04-14",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Insel Gruppe AG, University Hospital Bern",
"sponsor_slug": "insel-gruppe-ag-university-hospital-bern",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07230990",
"publication_url": "https://clinicaltrials.gov/study/NCT07230990",
"title": "Mechanisms Of Orbitofrontal Stimulation in Depression (MOOD)",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Subha Subramanian",
"sponsor_slug": "subha-subramanian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07495995",
"publication_url": "https://clinicaltrials.gov/study/NCT07495995",
"title": "A Single-center, Phase II Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Effect of S-adenosyl-L-methionine (SAMe) in Prevention of Hepatocellular Carcinoma Among Patients With Metabolic Dysfunction-associated Steatotic Liver Diseases (MASLD)-Related Cirrhosis",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07531745",
"publication_url": "https://clinicaltrials.gov/study/NCT07531745",
"title": "Phase 1-2, Open-Label, Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION337 in Patients With Dravet Syndrome",
"has_exemption": false,
"start_date": "2026-05-21",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594652",
"publication_url": "https://clinicaltrials.gov/study/NCT07594652",
"title": "USE of JORNAY PM® to TREAT ADHD in PEDIATRIC EPILEPSY",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hugo W. Moser Research Institute at Kennedy Krieger, Inc.",
"sponsor_slug": "hugo-w-moser-research-institute-at-kennedy-krieger-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07283497",
"publication_url": "https://clinicaltrials.gov/study/NCT07283497",
"title": "Itraconazole Therapy In Bronchiectasis With Airway Mold: A Single-Arm Pilot Trial Of Feasibility, Safety, And Impact On Respiratory Symptoms And Airway Microbiome Diversity",
"has_exemption": false,
"start_date": "2026-06-20",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07101666",
"publication_url": "https://clinicaltrials.gov/study/NCT07101666",
"title": "Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07608432",
"publication_url": "https://clinicaltrials.gov/study/NCT07608432",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of DYNE-251 Administered Intravenously in Ambulatory Male Participants 4 to 18 Years of Age With Duchenne Muscular Dystrophy Amenable to Exon-51 Skipping",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dyne Therapeutics",
"sponsor_slug": "dyne-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06548113",
"publication_url": "https://clinicaltrials.gov/study/NCT06548113",
"title": "Investigation of Sensory Synchronized Human Brain Imaging and Neuromodulation",
"has_exemption": false,
"start_date": "2026-07-13",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07416188",
"publication_url": "https://clinicaltrials.gov/study/NCT07416188",
"title": "Phase 1/Phase 2 Open Label Trial of a Novel Indenoisoquinolone C-MYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Neurological Disorders and Stroke (NINDS)",
"sponsor_slug": "national-institute-of-neurological-disorders-and-stroke-ninds",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07483255",
"publication_url": "https://clinicaltrials.gov/study/NCT07483255",
"title": "A Phase II Trial of Fetal Embolization for Vein of Galen Malformation",
"has_exemption": false,
"start_date": "2026-07-20",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Darren Orbach",
"sponsor_slug": "darren-orbach",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07628062",
"publication_url": "https://clinicaltrials.gov/study/NCT07628062",
"title": "Open-Label, Single-Arm Phase 2 Study Of Nogapendekin Alfa Inbakicept, PD-L1 T-HaNK, And Bevacizumab And Randomized Phase 2B Study Of Nogapendekin Alfa Inbakicept, Bevacizumab, And Tumor Treatment Fields With Or Without PD-L1 T-HaNK In Participants With Recurrent Or Progressive Glioblastoma",
"has_exemption": false,
"start_date": "2026-07-22",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ImmunityBio, Inc.",
"sponsor_slug": "immunitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07504601",
"publication_url": "https://clinicaltrials.gov/study/NCT07504601",
"title": "Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers",
"has_exemption": false,
"start_date": "2026-07-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Center for Complementary and Integrative Health (NCCIH)",
"sponsor_slug": "national-center-for-complementary-and-integrative-health-nccih",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06683534",
"publication_url": "https://clinicaltrials.gov/study/NCT06683534",
"title": "Use of Quercetin to Increase Resiliency to Palmitic Acid in the Human Microvasculature",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281924",
"publication_url": "https://clinicaltrials.gov/study/NCT07281924",
"title": "A Phase 1b/2 Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of Melphalan Percutaneous Hepatic Perfusion Therapy (HEPZATO KIT™) With Nivolumab and Relatlimab (Opdualag) in Patients With Metastatic Melanoma and Liver Metastasis",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07654426",
"publication_url": "https://clinicaltrials.gov/study/NCT07654426",
"title": "A Randomized Study of Dexrazoxane or Liposomal Doxorubicin in Newly Diagnosed Diffuse Large B-cell Lymphoma at High Risk for Heart Failure Events: the CARDIOPROTECT Trial",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07398404",
"publication_url": "https://clinicaltrials.gov/study/NCT07398404",
"title": "A Multiple Health Behavior Change Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07701928",
"publication_url": "https://clinicaltrials.gov/study/NCT07701928",
"title": "Daridorexant for the Treatment of Sleep Amongst Those With Alcohol Use Disorder Using the Addiction Neuroclinical Assessment Framework",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sterling McPherson",
"sponsor_slug": "sterling-mcpherson",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07261150",
"publication_url": "https://clinicaltrials.gov/study/NCT07261150",
"title": "Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)",
"has_exemption": false,
"start_date": "2026-09-15",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07607860",
"publication_url": "https://clinicaltrials.gov/study/NCT07607860",
"title": "Feasibility Clinical Evaluation of the Adaptilens Accommodating IOL",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Adaptilens, Inc.",
"sponsor_slug": "adaptilens-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07551583",
"publication_url": "https://clinicaltrials.gov/study/NCT07551583",
"title": "A Phase 2 Single Arm Study To Evaluate Safety And Preliminary Efficacy Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With Newly Diagnosed Early-Stage Non-Bulky Classical Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07721467",
"publication_url": "https://clinicaltrials.gov/study/NCT07721467",
"title": "Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin (NECTAR) in Aging and Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute on Aging (NIA)",
"sponsor_slug": "national-institute-on-aging-nia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07649070",
"publication_url": "https://clinicaltrials.gov/study/NCT07649070",
"title": "Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07032701",
"publication_url": "https://clinicaltrials.gov/study/NCT07032701",
"title": "Assessing the Impact of a Disposable Negative Pressure Wound Therapy Device on Surgical Wounds of the Lower Extremities Following Mohs Micrographic Surgery",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07477418",
"publication_url": "https://clinicaltrials.gov/study/NCT07477418",
"title": "PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP): A Phase Ib/II Open-Label Trial",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Vermont",
"sponsor_slug": "university-of-vermont",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07359872",
"publication_url": "https://clinicaltrials.gov/study/NCT07359872",
"title": "Relaxin Therapy for Atrial Fibrillation",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Deeptankar DeMazumder",
"sponsor_slug": "deeptankar-demazumder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07718984",
"publication_url": "https://clinicaltrials.gov/study/NCT07718984",
"title": "SWIFT-RELIEVE : Simultaneous Treatment of Widespread Pain In Fibromyalgia and PTSD: Randomized Evaluation of Live vs. Inactive Electrical VNS With PE-PC",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07719829",
"publication_url": "https://clinicaltrials.gov/study/NCT07719829",
"title": "Paired VNS For TBI Rehabilitation",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stony Brook University",
"sponsor_slug": "stony-brook-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06454110",
"publication_url": "https://clinicaltrials.gov/study/NCT06454110",
"title": "A Phase II, Open-Label Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)",
"has_exemption": false,
"start_date": "2028-02-29",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06318403",
"publication_url": "https://clinicaltrials.gov/study/NCT06318403",
"title": "Estradiol Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial",
"has_exemption": false,
"start_date": "2028-03-31",
"completion_date": "2030-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05968326",
"publication_url": "https://clinicaltrials.gov/study/NCT05968326",
"title": "A Phase II, Open-Label, Multicenter, Randomized Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Patients With Resected Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2023-10-18",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06179472",
"publication_url": "https://clinicaltrials.gov/study/NCT06179472",
"title": "Infant Survival and Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial",
"has_exemption": false,
"start_date": "2024-04-14",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Inna Lobeck",
"sponsor_slug": "inna-lobeck",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228104",
"publication_url": "https://clinicaltrials.gov/study/NCT07228104",
"title": "Adjuvant STeRoid Outcomes in Idiopathic Subglottic Stenosis",
"has_exemption": false,
"start_date": "2026-05-20",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07499583",
"publication_url": "https://clinicaltrials.gov/study/NCT07499583",
"title": "Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07701941",
"publication_url": "https://clinicaltrials.gov/study/NCT07701941",
"title": "A Phase 1b/2, Multicenter, Open-label, Dose Regimen Determination and Dose Expansion Trial to Evaluate the Safety, Tolerability, Anti-tumor Activity, and an Optimal Dose Regimen of Patritumab Deruxtecan (HER3-DXd) With Trastuzumab Deruxtecan (T-DXd) in Participants With Hormone Receptor Positive, HER2-low or HER2-ultralow, Unresectable or Metastatic Breast Cancer (HERTHENA-Breast02)",
"has_exemption": false,
"start_date": "2026-08-03",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07714551",
"publication_url": "https://clinicaltrials.gov/study/NCT07714551",
"title": "A Phase 2 Clinical Trial of Zanzalintinib in Patients With Unresectable and Progressive Metastatic Pheochromocytoma or Paraganglioma (MPPGs)",
"has_exemption": false,
"start_date": "2027-01-09",
"completion_date": "2031-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06919939",
"publication_url": "https://clinicaltrials.gov/study/NCT06919939",
"title": "Phase 2 Study of Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2026-01-07",
"completion_date": "2031-01-07",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07082842",
"publication_url": "https://clinicaltrials.gov/study/NCT07082842",
"title": "A Multicenter, Parallel, Randomized, Placebo (Double-blind) and Pirfenidone (Open-label) Controlled Phase III Clinical Trial Evaluating the Efficacy and Safety of HEC585 Tablets in Patients With Idiopathic Pulmonary Fibrosis (IPF)",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2031-01-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Sunshine Lake Pharma Co., Ltd.",
"sponsor_slug": "sunshine-lake-pharma-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07116967",
"publication_url": "https://clinicaltrials.gov/study/NCT07116967",
"title": "A Phase 3b/4 Multi-center, Randomized, Open-label, Long-term Safety Study of Deucravacitinib in Comparison to Ustekinumab in Participants With Moderate-to-Severe Plaque Psoriasis",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2031-01-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06615050",
"publication_url": "https://clinicaltrials.gov/study/NCT06615050",
"title": "A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2025-04-02",
"completion_date": "2031-01-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Incyte Corporation",
"sponsor_slug": "incyte-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609239",
"publication_url": "https://clinicaltrials.gov/study/NCT06609239",
"title": "An Open Label Extension Study to Evaluate the Long-term Safety and Efficacy of Subcutaneous Lunsekimig in Adult Participants With Asthma Who Participated in Study DRI16762 or ACT18301",
"has_exemption": false,
"start_date": "2024-09-30",
"completion_date": "2031-01-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07234032",
"publication_url": "https://clinicaltrials.gov/study/NCT07234032",
"title": "A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2031-01-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Insmed Incorporated",
"sponsor_slug": "insmed-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07465289",
"publication_url": "https://clinicaltrials.gov/study/NCT07465289",
"title": "A Phase 3, Open-Label, Extension Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis",
"has_exemption": false,
"start_date": "2026-07-27",
"completion_date": "2031-01-23",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03725059",
"publication_url": "https://clinicaltrials.gov/study/NCT03725059",
"title": "A Randomized, Double-Blind, Phase III Study of Pembrolizumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy for the Treatment of High-Risk Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (KEYNOTE-756)",
"has_exemption": false,
"start_date": "2018-12-27",
"completion_date": "2031-01-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06667700",
"publication_url": "https://clinicaltrials.gov/study/NCT06667700",
"title": "A Phase 3, Randomized, Placebo-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adults With COVID-19 at High Risk for Disease Progression",
"has_exemption": false,
"start_date": "2024-12-02",
"completion_date": "2031-01-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06914908",
"publication_url": "https://clinicaltrials.gov/study/NCT06914908",
"title": "A Single-arm Extension Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2031-01-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03076658",
"publication_url": "https://clinicaltrials.gov/study/NCT03076658",
"title": "Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers",
"has_exemption": false,
"start_date": "2016-09-30",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06185205",
"publication_url": "https://clinicaltrials.gov/study/NCT06185205",
"title": "Accelerated Super-Hypofractionated Breast Brachytherapy - ASHBY Trial",
"has_exemption": false,
"start_date": "2023-12-12",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06313203",
"publication_url": "https://clinicaltrials.gov/study/NCT06313203",
"title": "Trans-arterial Treatment of Patients With Intra-hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)",
"has_exemption": false,
"start_date": "2024-02-13",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oslo University Hospital",
"sponsor_slug": "oslo-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06543576",
"publication_url": "https://clinicaltrials.gov/study/NCT06543576",
"title": "A Prospective Cohort Study of Integrating Radiotherapy Into Chemotherapy With Pembrolizumab and Bevacizumab in Newly Diagnosed Stage IVB Cervical Cancer",
"has_exemption": false,
"start_date": "2025-07-29",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07059091",
"publication_url": "https://clinicaltrials.gov/study/NCT07059091",
"title": "Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD (COPD-OMA)",
"has_exemption": false,
"start_date": "2026-02-12",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318883",
"publication_url": "https://clinicaltrials.gov/study/NCT07318883",
"title": "A Randomized, Double-Blind, Multicenter, Phase II/III Clinical Study to Evaluate HLX07 (Recombinant Anti-EGFR Humanized Monoclonal Antibody Injection) in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Patients With Advanced Squamous Non-Small Cell Lung Cancer (sqNSCLC)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Henlius Biotech",
"sponsor_slug": "shanghai-henlius-biotech",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288112",
"publication_url": "https://clinicaltrials.gov/study/NCT07288112",
"title": "Clinical Study of DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma",
"has_exemption": false,
"start_date": "2026-04-06",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Diakonos Oncology Corporation",
"sponsor_slug": "diakonos-oncology-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226739",
"publication_url": "https://clinicaltrials.gov/study/NCT07226739",
"title": "Comprehensive Toileting Programming: Enuresis Treatment to a Randomized Clinical Trial of a Caregiver-Mediated Multidisciplinary Intervention for Encopresis",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07461584",
"publication_url": "https://clinicaltrials.gov/study/NCT07461584",
"title": "Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston University Charles River Campus",
"sponsor_slug": "boston-university-charles-river-campus",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07722598",
"publication_url": "https://clinicaltrials.gov/study/NCT07722598",
"title": "Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation",
"has_exemption": false,
"start_date": "2028-05-01",
"completion_date": "2031-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston University Charles River Campus",
"sponsor_slug": "boston-university-charles-river-campus",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03181867",
"publication_url": "https://clinicaltrials.gov/study/NCT03181867",
"title": "18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer",
"has_exemption": false,
"start_date": "2017-08-03",
"completion_date": "2031-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07527338",
"publication_url": "https://clinicaltrials.gov/study/NCT07527338",
"title": "Mechanisms of Cannabidiol and Sleep in the Context of Alcohol Use",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2031-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Boulder",
"sponsor_slug": "university-of-colorado-boulder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07493317",
"publication_url": "https://clinicaltrials.gov/study/NCT07493317",
"title": "Neutralizing Interleukin (IL)-6 Signaling to Reverse Immune Related Anhedonia in Patients With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2026-03-26",
"completion_date": "2031-02-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06312722",
"publication_url": "https://clinicaltrials.gov/study/NCT06312722",
"title": "Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study",
"has_exemption": false,
"start_date": "2024-02-07",
"completion_date": "2031-02-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Urotronic Inc.",
"sponsor_slug": "urotronic-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06401330",
"publication_url": "https://clinicaltrials.gov/study/NCT06401330",
"title": "Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2031-02-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03418038",
"publication_url": "https://clinicaltrials.gov/study/NCT03418038",
"title": "Phase2 Trial of High Dose Intravenous Ascorbic Acid as an Adjunct to Salvage Chemotherapy in Relapsed/ Refractory Lymphoma, Patients With Clonal Cytopenia of Undetermined Significance, and Chronic Myelomonocytic Leukemia",
"has_exemption": false,
"start_date": "2018-03-23",
"completion_date": "2031-02-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07178808",
"publication_url": "https://clinicaltrials.gov/study/NCT07178808",
"title": "PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER",
"has_exemption": false,
"start_date": "2021-04-16",
"completion_date": "2031-02-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Banner Health",
"sponsor_slug": "banner-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06618287",
"publication_url": "https://clinicaltrials.gov/study/NCT06618287",
"title": "A Phase 1/2a, Open-label, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BMS-986507 (BL-B01D1) Combinations in Adult Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-02-04",
"completion_date": "2031-02-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04251026",
"publication_url": "https://clinicaltrials.gov/study/NCT04251026",
"title": "A Phase 1/2, Multicenter, Open-Label Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL310 in Pediatric Participants With Hunter Syndrome",
"has_exemption": false,
"start_date": "2020-07-16",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06066580",
"publication_url": "https://clinicaltrials.gov/study/NCT06066580",
"title": "An Open-Label Extension Study to Assess the Long-term Effect of EDG-5506 on Safety, Biomarkers, and Functional Measures in Adults and Adolescents With Becker Muscular Dystrophy",
"has_exemption": false,
"start_date": "2023-11-02",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Edgewise Therapeutics, Inc.",
"sponsor_slug": "edgewise-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06302348",
"publication_url": "https://clinicaltrials.gov/study/NCT06302348",
"title": "A Phase 3b Open-Label Study of Long-Term Neurocognitive Outcomes in Children With Phenylketonuria Treated With Sepiapterin",
"has_exemption": false,
"start_date": "2024-03-04",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "PTC Therapeutics",
"sponsor_slug": "ptc-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06378866",
"publication_url": "https://clinicaltrials.gov/study/NCT06378866",
"title": "MC230502 Dynamic Investigator Initiated Enterprise (DIVINE) in Prostate Cancer",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06575192",
"publication_url": "https://clinicaltrials.gov/study/NCT06575192",
"title": "A Prospective, Multicenter, Open-Label, Non-Randomized, Controlled Pivotal Study to Evaluate the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix in Implant-Based Two Stage Prepectoral Breast Reconstruction Post-Mastectomy",
"has_exemption": false,
"start_date": "2024-11-05",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07277231",
"publication_url": "https://clinicaltrials.gov/study/NCT07277231",
"title": "A Phase 3, Open-Label, Randomized Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Patients With Previously Untreated Chronic Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2026-01-22",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07136415",
"publication_url": "https://clinicaltrials.gov/study/NCT07136415",
"title": "CELESTE: Comparative Effectiveness Study of behavioraL and Drug-rElated inSomnia Therapies for pEri- and Post-menopausal People",
"has_exemption": false,
"start_date": "2026-02-13",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222631",
"publication_url": "https://clinicaltrials.gov/study/NCT07222631",
"title": "An Open-Label, First-in-Human Phase 1/2, Dose-Escalation and Dose-Expansion/ Combination Therapy Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SB-4826 as a Single Agent in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas and in Combination With Rituximab in Adult Participants With Non-Hodgkin Lymphomas",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07441174",
"publication_url": "https://clinicaltrials.gov/study/NCT07441174",
"title": "A Multicenter, Open-Label, Phase Ib/II Clinical Trial of IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "InxMed (Shanghai) Co., Ltd.",
"sponsor_slug": "inxmed-shanghai-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07365995",
"publication_url": "https://clinicaltrials.gov/study/NCT07365995",
"title": "A Phase III, Randomized, Open-label Trial of BNT324 Versus Docetaxel With Prednisone/Prednisolone in Metastatic Castration-resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2026-04-22",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07172256",
"publication_url": "https://clinicaltrials.gov/study/NCT07172256",
"title": "A Pilot Study of CUE-101 in Combination With Pembrolizumab in Subjects With Newly Diagnosed, Locally Advanced HPV-16 Associated Head and Neck Cancer",
"has_exemption": false,
"start_date": "2026-05-07",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227350",
"publication_url": "https://clinicaltrials.gov/study/NCT07227350",
"title": "A Phase 2 Controlled Randomized Study of the Efficacy of L19IL2 or L19TNF or L19IL2/L19TNF Intralesional Injections for the Treatment of Locally Advanced Basal Cell Carcinoma (LaBCC)",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Philogen S.p.A.",
"sponsor_slug": "philogen-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07673887",
"publication_url": "https://clinicaltrials.gov/study/NCT07673887",
"title": "A Phase 3, Global, Multi-center, Double-blind, Randomized Study of ASP2138 Plus Chemotherapy (CAPOX or mFOLFOX6) With Pembrolizumab vs Placebo Plus Chemotherapy With or Without Pembrolizumab in First-line Treatment of Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma in Participants Whose Tumors Are HER2-negative and Claudin (CLDN) 18.2-positive",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07271355",
"publication_url": "https://clinicaltrials.gov/study/NCT07271355",
"title": "Investigation of Mitomycin C PIPAC - FOLFIRI Combination for Unresectable Appendiceal or Colorectal Peritoneal Metastases Treatment (IMPACT): A Multicenter, Randomized, Open-Label, Phase 3 Trial",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07620548",
"publication_url": "https://clinicaltrials.gov/study/NCT07620548",
"title": "A Randomized Phase II Study of the Efficacy of Laser Interstitial Thermal Therapy (LiTT) Combined With Cemiplimab Versus Physician's Choice Chemotherapy in Recurrent Glioblastomas",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227870",
"publication_url": "https://clinicaltrials.gov/study/NCT07227870",
"title": "A Phase 2 Study of Intratumoral Administration of L19IL2/L19TNF in Locally Advanced Basal Cell Carcinoma Patients Progressing or Intolerant to Systemic Treatment.",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Philogen S.p.A.",
"sponsor_slug": "philogen-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228442",
"publication_url": "https://clinicaltrials.gov/study/NCT07228442",
"title": "A Phase 2 Study of Intratumoral Administration of L19IL2/L19TNF in Locally Advanced Cutaneous Squamous Cell Carcinoma Patients Progressing on or Intolerant to Systemic Treatment",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Philogen S.p.A.",
"sponsor_slug": "philogen-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07704957",
"publication_url": "https://clinicaltrials.gov/study/NCT07704957",
"title": "A Randomized Controlled Trial of Doxycycline Post Exposure Prophylaxis to Prevent Incident Bacterial STIs Among Women in the United States",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2031-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Tulane University",
"sponsor_slug": "tulane-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05626114",
"publication_url": "https://clinicaltrials.gov/study/NCT05626114",
"title": "A Phase IIa, Multicenter, Open-label, Single-Arm Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2023-03-23",
"completion_date": "2031-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07511023",
"publication_url": "https://clinicaltrials.gov/study/NCT07511023",
"title": "Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum",
"has_exemption": false,
"start_date": "2026-09-25",
"completion_date": "2031-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07564401",
"publication_url": "https://clinicaltrials.gov/study/NCT07564401",
"title": "A Phase I/II Open-label Study of DJI136, a DLL3-targeted CAR-T Therapy, in Adult Patients With ES-SCLC",
"has_exemption": false,
"start_date": "2026-06-16",
"completion_date": "2031-03-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07518927",
"publication_url": "https://clinicaltrials.gov/study/NCT07518927",
"title": "Mapping Low-Intensity Focused Ultrasound (LIFU)-Evoked Brain Network Responses Using Intracranial Electrophysiological Recordings",
"has_exemption": false,
"start_date": "2026-03-04",
"completion_date": "2031-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06042140",
"publication_url": "https://clinicaltrials.gov/study/NCT06042140",
"title": "Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair: Single Arm Phase III Trial.",
"has_exemption": false,
"start_date": "2023-09-08",
"completion_date": "2031-03-08",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06592924",
"publication_url": "https://clinicaltrials.gov/study/NCT06592924",
"title": "A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response",
"has_exemption": false,
"start_date": "2025-05-28",
"completion_date": "2031-03-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06910813",
"publication_url": "https://clinicaltrials.gov/study/NCT06910813",
"title": "An Open-label, Multi-center, Phase I/II Study to Assess Safety, Tolerability and Efficacy of DFT383 in Pediatric Participants With Nephropathic Cystinosis, Followed by a Long-term Extension Phase",
"has_exemption": false,
"start_date": "2025-06-02",
"completion_date": "2031-03-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06616597",
"publication_url": "https://clinicaltrials.gov/study/NCT06616597",
"title": "Phase II Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer",
"has_exemption": false,
"start_date": "2025-02-13",
"completion_date": "2031-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04127578",
"publication_url": "https://clinicaltrials.gov/study/NCT04127578",
"title": "A Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)",
"has_exemption": false,
"start_date": "2020-01-03",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prevail Therapeutics",
"sponsor_slug": "prevail-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04746677",
"publication_url": "https://clinicaltrials.gov/study/NCT04746677",
"title": "Single-Center Investigational Device Exemption Trial: Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Grafts (PMEGs)",
"has_exemption": false,
"start_date": "2021-03-15",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05064540",
"publication_url": "https://clinicaltrials.gov/study/NCT05064540",
"title": "JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization",
"has_exemption": false,
"start_date": "2021-09-20",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Endologix",
"sponsor_slug": "endologix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05180591",
"publication_url": "https://clinicaltrials.gov/study/NCT05180591",
"title": "Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes",
"has_exemption": false,
"start_date": "2022-03-22",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05235165",
"publication_url": "https://clinicaltrials.gov/study/NCT05235165",
"title": "A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma",
"has_exemption": false,
"start_date": "2022-04-01",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05605899",
"publication_url": "https://clinicaltrials.gov/study/NCT05605899",
"title": "An Adaptive Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Axicabtagene Ciloleucel Versus Standard of Care Therapy as First-Line Therapy in Subjects With High-Risk Large B-Cell Lymphoma (ZUMA-23)",
"has_exemption": false,
"start_date": "2023-02-10",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06007677",
"publication_url": "https://clinicaltrials.gov/study/NCT06007677",
"title": "A Phase 2 Long-Term Open-Label Trial to Assess the Safety and Efficacy of Repeat Dosing of STAR-0215 in Adult Patients With Hereditary Angioedema (The ALPHA-SOLAR Trial)",
"has_exemption": false,
"start_date": "2023-09-26",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astria Therapeutics, Inc.",
"sponsor_slug": "astria-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06839456",
"publication_url": "https://clinicaltrials.gov/study/NCT06839456",
"title": "Phase 1/2 Study: CD45RA Depleted Peripheral Stem Cell Addback to Prevent Viral and Fungal Infections Following Alternative Donor TCRab/CD19 Depleted Hematopoietic Stem Cell Transplant",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07157774",
"publication_url": "https://clinicaltrials.gov/study/NCT07157774",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Muvalaplin on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Had a Prior Atherosclerotic Cardiovascular Event or Are at Risk for a First Atherosclerotic Cardiovascular Event",
"has_exemption": false,
"start_date": "2025-09-02",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07202598",
"publication_url": "https://clinicaltrials.gov/study/NCT07202598",
"title": "A Phase 2 Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis",
"has_exemption": false,
"start_date": "2025-11-12",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07549321",
"publication_url": "https://clinicaltrials.gov/study/NCT07549321",
"title": "A Phase 2/3 Study to Characterize and Evaluate the Efficacy, Safety, and Tolerability of hu14.18K322A Treatment Given in Combination With Chemotherapy in Participants With High-Risk Neuroblastoma",
"has_exemption": false,
"start_date": "2026-03-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Renaissance Pharma Ltd.",
"sponsor_slug": "renaissance-pharma-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07179003",
"publication_url": "https://clinicaltrials.gov/study/NCT07179003",
"title": "A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07303816",
"publication_url": "https://clinicaltrials.gov/study/NCT07303816",
"title": "STAT-CAT: Statin Therapy to Prevent Cancer Associated Venous Thromboembolism",
"has_exemption": false,
"start_date": "2026-06-11",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07466316",
"publication_url": "https://clinicaltrials.gov/study/NCT07466316",
"title": "A Randomized Phase 3 Study to Compare VAC (Higher Cyclophosphamide Dose and Intensity) Versus VAC/VI (Lower Cyclophosphamide Dose and Intensity) Plus Maintenance Therapy in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma",
"has_exemption": false,
"start_date": "2026-06-22",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07346209",
"publication_url": "https://clinicaltrials.gov/study/NCT07346209",
"title": "STudy of Real-world Individualized Precision-oncology",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07129473",
"publication_url": "https://clinicaltrials.gov/study/NCT07129473",
"title": "Hyperemesis Gravidarum Risk Reduction With Metformin",
"has_exemption": false,
"start_date": "2026-07-13",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07346157",
"publication_url": "https://clinicaltrials.gov/study/NCT07346157",
"title": "PNOC044: Liothyronine (L-T3) in Combination With Bevacizumab, Irinotecan and Temozolomide (BIT) for Progressive or Relapsed Medulloblastoma (Cohort 1) or as Monotherapy for Medulloblastoma With Minimal Residual Disease (Cohort 2)",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sabine Mueller, MD, PhD",
"sponsor_slug": "sabine-mueller-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07503782",
"publication_url": "https://clinicaltrials.gov/study/NCT07503782",
"title": "Investigating Oleoylethanolamide (OEA) as a Novel Multi-System Based Therapeutic for Young Adults With Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04756063",
"publication_url": "https://clinicaltrials.gov/study/NCT04756063",
"title": "Parenteral Ascorbic Acid Repletion in TransplantatIon (PARTI): A Randomized, Double-Blinded, Placebo-Controlled Trial",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07715734",
"publication_url": "https://clinicaltrials.gov/study/NCT07715734",
"title": "A Phase 2 Study of Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma (CONTRAC-2)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04387305",
"publication_url": "https://clinicaltrials.gov/study/NCT04387305",
"title": "Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC): An Efficacy Study",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2031-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daniel Nishijima, MD, MAS",
"sponsor_slug": "daniel-nishijima-md-mas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06785415",
"publication_url": "https://clinicaltrials.gov/study/NCT06785415",
"title": "Phase 1/2 Trial of Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for Relapsed Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2031-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06863272",
"publication_url": "https://clinicaltrials.gov/study/NCT06863272",
"title": "MK-2400-01A Substudy: A Phase 1/2, Open-label Umbrella Substudy of MK-2400-U01 Master Protocol to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan-based Treatment Combinations or Ifinatamab Deruxtecan Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (IDeate-Prostate02)",
"has_exemption": false,
"start_date": "2025-07-03",
"completion_date": "2031-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227454",
"publication_url": "https://clinicaltrials.gov/study/NCT07227454",
"title": "A Double-blind, Randomized, Psychoactive Placebo-controlled Study to Evaluate the Efficacy and Safety of Intranasal Esketamine 84 mg in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder in Adolescent Participants With Acute Suicidal Ideation or Behavior",
"has_exemption": false,
"start_date": "2026-01-08",
"completion_date": "2031-04-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05367440",
"publication_url": "https://clinicaltrials.gov/study/NCT05367440",
"title": "A Multi-arm, Open-label Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of AZD5305 in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer (PETRANHA)",
"has_exemption": false,
"start_date": "2022-06-02",
"completion_date": "2031-04-11",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06408259",
"publication_url": "https://clinicaltrials.gov/study/NCT06408259",
"title": "A Phase 3, Multicenter, Double-blind, Active-controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Ozanimod Compared to Oral Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-04-08",
"completion_date": "2031-04-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07667478",
"publication_url": "https://clinicaltrials.gov/study/NCT07667478",
"title": "NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2031-04-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Chi-Ying (Roy) Lin",
"sponsor_slug": "chi-ying-roy-lin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07636564",
"publication_url": "https://clinicaltrials.gov/study/NCT07636564",
"title": "A Phase II Randomized Study of Blinatumomab With or Without Revumenib for Patients With KMT2A-Translocation B-Cell Acute Lymphoblastic Leukemia (ALL)/ Acute Leukemia With Ambiguous Lineage (ALAL) With Persistent Measurable Residual Disease (MRD)",
"has_exemption": false,
"start_date": "2026-10-14",
"completion_date": "2031-04-16",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06912698",
"publication_url": "https://clinicaltrials.gov/study/NCT06912698",
"title": "A Phase III Randomized Controlled Non-Inferiority Clinical Trial Comparing Reduced-Dose Versus Standard-Dose Radiotherapy Based on Treatment Response in Early-Stage Nasopharyngeal Carcinoma",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2031-04-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Hai-Qiang Mai,MD,PhD",
"sponsor_slug": "hai-qiang-maimdphd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05675410",
"publication_url": "https://clinicaltrials.gov/study/NCT05675410",
"title": "A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy With Immuno-oncology Therapy for Children and Adults With Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2023-05-11",
"completion_date": "2031-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06679101",
"publication_url": "https://clinicaltrials.gov/study/NCT06679101",
"title": "A Phase 3, Randomized, Open-label Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)",
"has_exemption": false,
"start_date": "2024-12-16",
"completion_date": "2031-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05335876",
"publication_url": "https://clinicaltrials.gov/study/NCT05335876",
"title": "Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 IT or OAV101 IV in Clinical Trials",
"has_exemption": false,
"start_date": "2022-12-19",
"completion_date": "2031-04-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01958086",
"publication_url": "https://clinicaltrials.gov/study/NCT01958086",
"title": "Visuomotor Prosthetic for Paralysis",
"has_exemption": false,
"start_date": "2013-10-01",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Richard A. Andersen, PhD",
"sponsor_slug": "richard-a-andersen-phd",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05552222",
"publication_url": "https://clinicaltrials.gov/study/NCT05552222",
"title": "A Phase 3 Randomized Study Comparing Teclistamab in Combination With Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab SC and Lenalidomide (Tal-DR) Versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma Who Are Either Ineligible or Not Intended for Autologous Stem Cell Transplant as Initial Therapy",
"has_exemption": false,
"start_date": "2022-10-25",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06799195",
"publication_url": "https://clinicaltrials.gov/study/NCT06799195",
"title": "A Phase II Randomized Trial to Optimize GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation in Older Adults With Hematological Malignancies: the PROMISE Trial",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07558759",
"publication_url": "https://clinicaltrials.gov/study/NCT07558759",
"title": "Temporal Interference in Psychiatry (TIP): Neuromodulation Using Temporal Interference",
"has_exemption": false,
"start_date": "2026-04-07",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227285",
"publication_url": "https://clinicaltrials.gov/study/NCT07227285",
"title": "Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy Expressing a Transgene Encoding the Light Chain of Botulinum Toxin F",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Cyllene Therapeutics",
"sponsor_slug": "cyllene-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07387549",
"publication_url": "https://clinicaltrials.gov/study/NCT07387549",
"title": "A Phase III, Multicentre, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis",
"has_exemption": false,
"start_date": "2026-05-14",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07332182",
"publication_url": "https://clinicaltrials.gov/study/NCT07332182",
"title": "Multicenter Prospective Randomized Study of MaioRegenTM Prime vs. Debridement (Surgical Standard of Care (SSOC)) for the Treatment of Osteochondral Lesion of the Knee Joint - OSTEOCONFIRM Study",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fin-Ceramica Faenza Spa",
"sponsor_slug": "fin-ceramica-faenza-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07021937",
"publication_url": "https://clinicaltrials.gov/study/NCT07021937",
"title": "Investigating Brain PLASTICity and GLP-1 Receptor Agonists in the Treatment of Obesity: The PLASTIC Trial",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06964230",
"publication_url": "https://clinicaltrials.gov/study/NCT06964230",
"title": "A Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled Multi-Center Study to Evaluate the Safety and Efficacy of T3D-959 in Subjects With Mild-to-Moderate Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-10-26",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "T3D Therapeutics, Inc.",
"sponsor_slug": "t3d-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07485010",
"publication_url": "https://clinicaltrials.gov/study/NCT07485010",
"title": "A Multi-centre, Randomised Trial Comparing a Novel Combination Treatment (Arm D - Intravenous Sulbactam-durlobactam in Combination With Intravenous Ceftriaxone, Oral Amoxicillin, Oral Azithromycin and Oral Clofazimine) Versus Standard of Care Treatments for the Intensive Phase of Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial",
"has_exemption": false,
"start_date": "2027-04-30",
"completion_date": "2031-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Queensland",
"sponsor_slug": "the-university-of-queensland",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05991388",
"publication_url": "https://clinicaltrials.gov/study/NCT05991388",
"title": "A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2024-05-02",
"completion_date": "2031-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Birmingham",
"sponsor_slug": "university-of-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07457385",
"publication_url": "https://clinicaltrials.gov/study/NCT07457385",
"title": "Congenital Syphilis Treatment Trial (CONSISTENT): Phase IV, Open-label, Randomized Controlled Trial of Amoxicillin vs. Benzathine in Neonates With Possible Congenital Syphilis",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2031-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288359",
"publication_url": "https://clinicaltrials.gov/study/NCT07288359",
"title": "An Open-label, Multi-center, Phase I/II Study of GVV858 as a Single Agent and in Combination With Endocrine Therapy in Patients With Advanced Hormone Receptor Positive, HER2- Negative Breast Cancer and Other Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-12-29",
"completion_date": "2031-05-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07468903",
"publication_url": "https://clinicaltrials.gov/study/NCT07468903",
"title": "Phase II Trial of Focal Radiation Therapy in Patients With Prostate Cancer",
"has_exemption": false,
"start_date": "2026-05-11",
"completion_date": "2031-05-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07497607",
"publication_url": "https://clinicaltrials.gov/study/NCT07497607",
"title": "Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma (REDUCE-30)",
"has_exemption": false,
"start_date": "2026-05-13",
"completion_date": "2031-05-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Sara Medek",
"sponsor_slug": "sara-medek",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06674577",
"publication_url": "https://clinicaltrials.gov/study/NCT06674577",
"title": "A Multicenter, Rollover Study to Evaluate the Long-Term Safety and Efficacy of Atacicept",
"has_exemption": false,
"start_date": "2024-12-01",
"completion_date": "2031-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Vera Therapeutics, Inc.",
"sponsor_slug": "vera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06710626",
"publication_url": "https://clinicaltrials.gov/study/NCT06710626",
"title": "CONVOY: An Early Feasibility Study of Neural Control of Assistive Devices Via Brain-Computer Interface Technology",
"has_exemption": false,
"start_date": "2024-11-25",
"completion_date": "2031-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Neuralink Corp",
"sponsor_slug": "neuralink-corp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07613099",
"publication_url": "https://clinicaltrials.gov/study/NCT07613099",
"title": "Evaluation of Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74 PET/CT Imaging)",
"has_exemption": false,
"start_date": "2026-07-29",
"completion_date": "2031-05-26",
"has_results": false,
"results_due": false,
"sponsor_name": "National Heart, Lung, and Blood Institute (NHLBI)",
"sponsor_slug": "national-heart-lung-and-blood-institute-nhlbi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07444489",
"publication_url": "https://clinicaltrials.gov/study/NCT07444489",
"title": "An Open-Label Long-Term Extension Study of Felzartamab in Participants With Antibody-Mediated Rejection or Microvascular Inflammation Previously Enrolled in TRANSCEND or TRANSPIRE",
"has_exemption": false,
"start_date": "2026-04-16",
"completion_date": "2031-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05561387",
"publication_url": "https://clinicaltrials.gov/study/NCT05561387",
"title": "A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of \"Intermediate Fit\" Comparing Upfront Three-Drug Induction Regimens Followed by Double or Single-Agent Maintenance",
"has_exemption": false,
"start_date": "2023-10-12",
"completion_date": "2031-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06919003",
"publication_url": "https://clinicaltrials.gov/study/NCT06919003",
"title": "Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (RTB-021)",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2031-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07650188",
"publication_url": "https://clinicaltrials.gov/study/NCT07650188",
"title": "Stimulating the Aging Brain: Noninvasive Brain and Sensory Stimulation Strategies in Aging",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07650643",
"publication_url": "https://clinicaltrials.gov/study/NCT07650643",
"title": "EEG Biomarkers for Pediatric ADHD Treatment Stratification",
"has_exemption": false,
"start_date": "2026-09-15",
"completion_date": "2031-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07662928",
"publication_url": "https://clinicaltrials.gov/study/NCT07662928",
"title": "Epcoritamab in Combination With Dose Adjusted R-EPOCH for High Risk Burkitt Lymphoma (BL) (BEDROCK Study)",
"has_exemption": false,
"start_date": "2026-09-17",
"completion_date": "2031-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AIDS Malignancy Consortium",
"sponsor_slug": "aids-malignancy-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03314181",
"publication_url": "https://clinicaltrials.gov/study/NCT03314181",
"title": "A Phase 1/2, Multicenter, Dose-Escalation and Expansion Study of Combination Therapy With Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Subjects With Relapsed or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2018-04-02",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04923958",
"publication_url": "https://clinicaltrials.gov/study/NCT04923958",
"title": "Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) Study",
"has_exemption": false,
"start_date": "2021-04-14",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05856370",
"publication_url": "https://clinicaltrials.gov/study/NCT05856370",
"title": "The Ailliance Post-Market Clinical Study: All enablIng technoLogies, bioLogics, IDS, And Core spiNe produCt collEction",
"has_exemption": false,
"start_date": "2023-05-01",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Spinal and Biologics",
"sponsor_slug": "medtronic-spinal-and-biologics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05866536",
"publication_url": "https://clinicaltrials.gov/study/NCT05866536",
"title": "Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years",
"has_exemption": false,
"start_date": "2023-05-04",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07543120",
"publication_url": "https://clinicaltrials.gov/study/NCT07543120",
"title": "A Multicenter Open-label Extension Study to Evaluate Long-term Safety and Efficacy of QCZ484 in Hypertensive Patients.",
"has_exemption": false,
"start_date": "2026-05-07",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07479797",
"publication_url": "https://clinicaltrials.gov/study/NCT07479797",
"title": "A Phase 3, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy",
"has_exemption": false,
"start_date": "2026-05-22",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07428148",
"publication_url": "https://clinicaltrials.gov/study/NCT07428148",
"title": "Phase I/II Trial of Induction Lattice-Based Radiotherapy and Chemoimmunotherapy Preceding Response-Adapted Definitive Chemoradiation for Non-Low Risk Oropharyngeal Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07607665",
"publication_url": "https://clinicaltrials.gov/study/NCT07607665",
"title": "Paired Stimulation of Hand Motor Cortex and Median Nerve to Induce Spinal Cord Plasticity in Hemiplegic Cerebral Palsy",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07636785",
"publication_url": "https://clinicaltrials.gov/study/NCT07636785",
"title": "A Phase 1 and 2 First-in-human, Open-label, Multicenter Study to Assess the Safety, Tolerability and Preliminary Efficacy of VMD-102 in Participants With Hepatocellular Carcinoma and Other Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VM Discovery, Inc.",
"sponsor_slug": "vm-discovery-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07278362",
"publication_url": "https://clinicaltrials.gov/study/NCT07278362",
"title": "Safety of Intramuscular Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07472322",
"publication_url": "https://clinicaltrials.gov/study/NCT07472322",
"title": "UW26001 Phase I/II Study on the Safety, Tolerability, and Preliminary Efficacy of ASTX727 (Decitabine/Cedazuridine) and Retifanlimab-dlwr in Patients With Advanced Merkel Cell Carcinoma Who Have Progressed on Anti-PD-(L)1 Inhibitor",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07704385",
"publication_url": "https://clinicaltrials.gov/study/NCT07704385",
"title": "Enhancing Rehabilitation in Aging Study (ERAS)",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07623187",
"publication_url": "https://clinicaltrials.gov/study/NCT07623187",
"title": "A Two-part, Phase 2b/Phase 3 Double-blinded, Randomized Study of IPN60340 in Combination With Azacitidine and Venetoclax Versus Placebo in Combination With Azacitidine and Venetoclax in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy.",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07167953",
"publication_url": "https://clinicaltrials.gov/study/NCT07167953",
"title": "MRI Technology for Greater Efficiency and Improved Value",
"has_exemption": false,
"start_date": "2028-08-31",
"completion_date": "2031-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02375204",
"publication_url": "https://clinicaltrials.gov/study/NCT02375204",
"title": "A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) With High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide Followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors",
"has_exemption": false,
"start_date": "2015-08-06",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance for Clinical Trials in Oncology",
"sponsor_slug": "alliance-for-clinical-trials-in-oncology",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06967610",
"publication_url": "https://clinicaltrials.gov/study/NCT06967610",
"title": "Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07547917",
"publication_url": "https://clinicaltrials.gov/study/NCT07547917",
"title": "Improving the Measurement of Neonatal High Blood Pressure Using the Boppli Device",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07565155",
"publication_url": "https://clinicaltrials.gov/study/NCT07565155",
"title": "A Phase 2 Trial of Lorigerlimab (MGD019) in Patients With Pancreatic Adenocarcinoma and Homologous Recombination Deficiency",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Peter Hosein, MD",
"sponsor_slug": "peter-hosein-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07321912",
"publication_url": "https://clinicaltrials.gov/study/NCT07321912",
"title": "A Phase II Open Label Basket Trial Study Using Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Milton S. Hershey Medical Center",
"sponsor_slug": "milton-s-hershey-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07415772",
"publication_url": "https://clinicaltrials.gov/study/NCT07415772",
"title": "The Effect of Right dlPFC cTBS on Acute Measures of Anxiety, Functional Connectivity, and TMS-evoked BOLD Responses.",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158567",
"publication_url": "https://clinicaltrials.gov/study/NCT07158567",
"title": "Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low Back PaiN Treatment: VIBRANT",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04007276",
"publication_url": "https://clinicaltrials.gov/study/NCT04007276",
"title": "The Effect of Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients Using Brimonidine 0.2%, 0.15%, or 0.1%",
"has_exemption": false,
"start_date": "2026-11-10",
"completion_date": "2031-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Tulane University",
"sponsor_slug": "tulane-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07340541",
"publication_url": "https://clinicaltrials.gov/study/NCT07340541",
"title": "TBCRC Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies (EVOLVE-BDT)",
"has_exemption": false,
"start_date": "2026-02-16",
"completion_date": "2031-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07604233",
"publication_url": "https://clinicaltrials.gov/study/NCT07604233",
"title": "Phase Ib/II of the Combination of Fludarabine, Cytarabine, Idarubicin, G-CSF (FLAG-Ida) With Venetoclax and Asciminib in Patients With Advanced Phase Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2031-06-03",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04657822",
"publication_url": "https://clinicaltrials.gov/study/NCT04657822",
"title": "An Open-label, Multi-center, Phase IV, Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study",
"has_exemption": false,
"start_date": "2021-06-10",
"completion_date": "2031-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222553",
"publication_url": "https://clinicaltrials.gov/study/NCT07222553",
"title": "Open-label, Uncontrolled, Multicenter Trial to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Children From 2 Years to Less Than 18 Years of Age With Immunoglobulin G4-related Disease (IgG4-RD)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05769777",
"publication_url": "https://clinicaltrials.gov/study/NCT05769777",
"title": "An Open-Label Multinational, Multicenter Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis",
"has_exemption": false,
"start_date": "2023-04-03",
"completion_date": "2031-06-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02065011",
"publication_url": "https://clinicaltrials.gov/study/NCT02065011",
"title": "An Open-label Study to Determine the Long-term Safety, Tolerability and Biological Activity of SAR421869 in Patients With Usher Syndrome Type 1B",
"has_exemption": false,
"start_date": "2013-09-12",
"completion_date": "2031-06-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06482684",
"publication_url": "https://clinicaltrials.gov/study/NCT06482684",
"title": "Early Treatment Intensification in Patients With High Risk Mantle Cell Lymphoma Using CAR-T-cell Treatment After an Abbreviated Induction Therapy With Rituximab and Ibrutinib and 6 Months Ibrutinib Maintenance (Arm A) as Compared to Standard of Care Induction and Maintenance (Arm B)",
"has_exemption": false,
"start_date": "2024-02-15",
"completion_date": "2031-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Christian Schmidt, MD",
"sponsor_slug": "christian-schmidt-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07646678",
"publication_url": "https://clinicaltrials.gov/study/NCT07646678",
"title": "A Long-term Extension Trial to Evaluate the Safety and Tolerability of TAK-360 in Participants With Selected Central Hypersomnia Conditions",
"has_exemption": false,
"start_date": "2026-06-11",
"completion_date": "2031-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07711002",
"publication_url": "https://clinicaltrials.gov/study/NCT07711002",
"title": "A Randomized, Double-Blind, Placebo-Controlled, 2-Cohort, Phase III Study of Saruparib Combined With Physician's Choice of Androgen Receptor Pathway Inhibitor in Patients With Metastatic Hormone-Sensitive Prostate Cancer, Previously Treated With Docetaxel or PSMA-directed 177Lutetium-Containing Therapy Without Disease Progression, and With Prostate-Specific Antigen ≥ 0.2 ng/mL: EvoPAR-Prostate05",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2031-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05805826",
"publication_url": "https://clinicaltrials.gov/study/NCT05805826",
"title": "A PHASE 1/2 RANDOMIZED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND IMMUNOPERSISTENCE OF A CLOSTRIDIOIDES DIFFICILE VACCINE ADMINISTERED WITH NOVEL ADJUVANTS IN HEALTHY ADULTS",
"has_exemption": false,
"start_date": "2023-03-23",
"completion_date": "2031-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06363994",
"publication_url": "https://clinicaltrials.gov/study/NCT06363994",
"title": "A Randomized, Double-Blind, Multicenter, Placebo-Controlled Phase 3 Study of Orelabrutinib in Combination with Rituximab and Bendamustine (BR) Vs. BR in Subjects with Treatment-Naїve Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2024-05-29",
"completion_date": "2031-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "InnoCare Pharma Inc.",
"sponsor_slug": "innocare-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06858319",
"publication_url": "https://clinicaltrials.gov/study/NCT06858319",
"title": "A Multicenter Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Zigakibart in Adults With Primary IgA Nephropathy.",
"has_exemption": false,
"start_date": "2025-07-28",
"completion_date": "2031-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06134375",
"publication_url": "https://clinicaltrials.gov/study/NCT06134375",
"title": "Novel Targeting of the Microenvironment to Decrease Metastatic Recurrence of High-Risk TNBC: A Randomized Phase II Study of Tetrathiomolybdate (TM) Plus Capecitabine in Patients With Breast Cancer at High Risk of Recurrence",
"has_exemption": false,
"start_date": "2024-11-26",
"completion_date": "2031-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Dartmouth-Hitchcock Medical Center",
"sponsor_slug": "dartmouth-hitchcock-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03424018",
"publication_url": "https://clinicaltrials.gov/study/NCT03424018",
"title": "A Phase 3, Open-Label Long-Term Extension Study to Evaluate the Safety and Efficacy of BMN 111 in Children With Achondroplasia",
"has_exemption": false,
"start_date": "2017-12-12",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04923126",
"publication_url": "https://clinicaltrials.gov/study/NCT04923126",
"title": "SJ901: Phase 1/2 Evaluation of Single Agent Mirdametinib (PD-0325901), a Brain-Penetrant MEK1/2 Inhibitor, for the Treatment of Children, Adolescents, and Young Adults With Low-Grade Glioma",
"has_exemption": false,
"start_date": "2021-06-21",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Jude Children's Research Hospital",
"sponsor_slug": "st-jude-childrens-research-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05606614",
"publication_url": "https://clinicaltrials.gov/study/NCT05606614",
"title": "An Open-label Phase 1/2/3 Study Consisting of a Phase 1/2 Safety and Dose-escalation and Phase 3 Dose-expansion Study to Evaluate Safety and Efficacy of a Single Intrathecal Administration of TSHA-102, an AAV9-Delivered Gene Therapy in Females With Rett Syndrome",
"has_exemption": false,
"start_date": "2023-03-06",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Taysha Gene Therapies, Inc.",
"sponsor_slug": "taysha-gene-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06278870",
"publication_url": "https://clinicaltrials.gov/study/NCT06278870",
"title": "Disitamab Vedotin in Combination With Pyrotinib Versus THP in the First-line Treatment for HER2-positive Advanced Breast Cancer, a Multicentre, Randomized, Double-blind Controlled, Phase III Trial",
"has_exemption": false,
"start_date": "2023-09-06",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University",
"sponsor_slug": "sun-yat-sen-memorial-hospital-of-sun-yat-sen-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07204938",
"publication_url": "https://clinicaltrials.gov/study/NCT07204938",
"title": "A Phase 3 Trial to Evaluate the Long-Term Safety and Efficacy of Navenibart in Participants With Hereditary Angioedema - ORBIT-EXPANSE",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Astria Therapeutics, Inc.",
"sponsor_slug": "astria-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07462507",
"publication_url": "https://clinicaltrials.gov/study/NCT07462507",
"title": "Investigation of Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1",
"has_exemption": false,
"start_date": "2026-04-16",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07660614",
"publication_url": "https://clinicaltrials.gov/study/NCT07660614",
"title": "A First-in-Human, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study of Intrathecally Administered LTX-002 in Adult Participants With Amyotrophic Lateral Sclerosis",
"has_exemption": false,
"start_date": "2026-04-29",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Leal Therapeutics, Inc",
"sponsor_slug": "leal-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07490301",
"publication_url": "https://clinicaltrials.gov/study/NCT07490301",
"title": "Phase 2/3 Open Label Randomized Study of Telisotuzumab Adizutecan in Combination With FOLFOX Compared to Standard of Care in Subjects With First-Line Metastatic Pancreatic Ductal Adenocarcinoma - AndroMETa-PDAC-288",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07480564",
"publication_url": "https://clinicaltrials.gov/study/NCT07480564",
"title": "ASPIRE Study: A Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of a Single Intrathecal Administration of TSHA-102, an AAV9-Delivered Gene Therapy, for the Treatment of Pediatric Females Aged >2 to <4 Years With Rett Syndrome",
"has_exemption": false,
"start_date": "2026-05-08",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Taysha Gene Therapies, Inc.",
"sponsor_slug": "taysha-gene-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07526948",
"publication_url": "https://clinicaltrials.gov/study/NCT07526948",
"title": "Vaginal Estradiol Versus Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms, Dysbiosis and Markers of Latency Reversal in Menopausal Women Living With HIV",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Albert Einstein College of Medicine",
"sponsor_slug": "albert-einstein-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325487",
"publication_url": "https://clinicaltrials.gov/study/NCT07325487",
"title": "Adaptive Deep Brain Stimulation Targeting the Interposed Nucleus to Treat Spinocerebellar Ataxia",
"has_exemption": false,
"start_date": "2026-06-02",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07630649",
"publication_url": "https://clinicaltrials.gov/study/NCT07630649",
"title": "Evaluation of the Safety and Tolerability of Ixoberogene Soroparvovec (Ixo-vec) Intravitreal Gene Therapy in the Second (Contralateral) Eye of Participants With Bilateral Neovascular Age-related Macular Degeneration.",
"has_exemption": false,
"start_date": "2026-06-02",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Adverum Biotechnologies, Inc.",
"sponsor_slug": "adverum-biotechnologies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07582120",
"publication_url": "https://clinicaltrials.gov/study/NCT07582120",
"title": "A Pilot Mechanistic Study of Psilocybin-Assisted Therapy as a Treatment for Depression",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325149",
"publication_url": "https://clinicaltrials.gov/study/NCT07325149",
"title": "Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bronx VA Medical Center",
"sponsor_slug": "bronx-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06052956",
"publication_url": "https://clinicaltrials.gov/study/NCT06052956",
"title": "A Phase 2 Study to Assess Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07329153",
"publication_url": "https://clinicaltrials.gov/study/NCT07329153",
"title": "Neuronavigated and Non-Neuronavigated Accelerated Intermittent Theta-Burst Stimulation for Treatment-Resistant Depression A Sham-Controlled Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07635056",
"publication_url": "https://clinicaltrials.gov/study/NCT07635056",
"title": "Haploidentical Donor Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Neuroblastoma",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07138274",
"publication_url": "https://clinicaltrials.gov/study/NCT07138274",
"title": "A Phase II, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Metyrapone in Subjects Diagnosed With Mild Autonomous Cortisol Secretion (MACS)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222046",
"publication_url": "https://clinicaltrials.gov/study/NCT07222046",
"title": "Identifying Residual Connectivity in Veterans With Spinal Cord Injury for Precision Neurorehabilitation",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07685886",
"publication_url": "https://clinicaltrials.gov/study/NCT07685886",
"title": "MIRACLE-T2D Montelukast Intervention for Renal, Cardiovascular and Eye Health in Type 2 Diabetes",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07699237",
"publication_url": "https://clinicaltrials.gov/study/NCT07699237",
"title": "REPLAT- A Multicenter Phase II Trial to Evaluate Rechallenge With Platinum-based Chemotherapy (Carboplatin, Etoposide) for Progression During Tarlatamab Therapy in Relapsed Extensive Disease Small-cell Lung Cancer (SCLC)",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Cologne",
"sponsor_slug": "university-of-cologne",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07449299",
"publication_url": "https://clinicaltrials.gov/study/NCT07449299",
"title": "Rct Assessing Pregnancy - Piroxicam for Ec With Levonorgestrel",
"has_exemption": false,
"start_date": "2027-03-31",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06699966",
"publication_url": "https://clinicaltrials.gov/study/NCT06699966",
"title": "Stony Brook Medicine Anti-Inflammatory Trial",
"has_exemption": false,
"start_date": "2027-06-30",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stony Brook University",
"sponsor_slug": "stony-brook-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06545695",
"publication_url": "https://clinicaltrials.gov/study/NCT06545695",
"title": "Epidermal Growth Factor Receptor Inhibition for Keratinopathies",
"has_exemption": false,
"start_date": "2027-07-01",
"completion_date": "2031-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04990921",
"publication_url": "https://clinicaltrials.gov/study/NCT04990921",
"title": "A Phase 2 Study of Palliative Radiation in Combination with Pembrolizumab in Subjects with Unresectable Metastatic Stage IV Breast Cancer: Twisted Pink",
"has_exemption": false,
"start_date": "2021-09-02",
"completion_date": "2031-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Louisville",
"sponsor_slug": "university-of-louisville",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05027945",
"publication_url": "https://clinicaltrials.gov/study/NCT05027945",
"title": "A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome",
"has_exemption": false,
"start_date": "2023-02-23",
"completion_date": "2031-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07508995",
"publication_url": "https://clinicaltrials.gov/study/NCT07508995",
"title": "A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2031-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05929664",
"publication_url": "https://clinicaltrials.gov/study/NCT05929664",
"title": "Neoadjuvant REGN2810 (Cemiplimab) or REGN2810 (Cemiplimab) Plus REGN3767 (Fianlimab) in Cutaneous Basal Cell Carcinoma of the Head and Neck",
"has_exemption": false,
"start_date": "2023-07-05",
"completion_date": "2031-07-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Jefferson University",
"sponsor_slug": "thomas-jefferson-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07232602",
"publication_url": "https://clinicaltrials.gov/study/NCT07232602",
"title": "A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Study of Investigational Agents in Combination With Enfortumab Vedotin Plus Pembrolizumab as First-Line Treatment in Participants With Locally Advanced or Metastatic Urothelial Carcinoma: KEYMAKER-U04-Substudy 04D",
"has_exemption": false,
"start_date": "2026-02-09",
"completion_date": "2031-07-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07493304",
"publication_url": "https://clinicaltrials.gov/study/NCT07493304",
"title": "A 2-Part, Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against Factor XI, for the Treatment and Secondary Prevention of Venous Thromboembolism in Participants With Solid and Hematologic Cancers (ROXI-CAT-II)",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-07-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07392892",
"publication_url": "https://clinicaltrials.gov/study/NCT07392892",
"title": "A PHASE 2/3 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC GASTRIC, GASTROESOPHAGEAL JUNCTION, OR ESOPHAGEAL ADENOCARCINOMA",
"has_exemption": false,
"start_date": "2026-05-14",
"completion_date": "2031-07-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06538337",
"publication_url": "https://clinicaltrials.gov/study/NCT06538337",
"title": "Hypofractionated External Beam Radiotherapy With Adaptive Planning for Endometrial and Cervical Cancers (HERA Trial)",
"has_exemption": false,
"start_date": "2024-07-24",
"completion_date": "2031-07-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07598825",
"publication_url": "https://clinicaltrials.gov/study/NCT07598825",
"title": "A Phase 2/3, Randomized, Double-blind, Multicenter, Placebo-controlled Study of Inebilizumab in Participants With Autoimmune Hepatitis",
"has_exemption": false,
"start_date": "2026-09-07",
"completion_date": "2031-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03773965",
"publication_url": "https://clinicaltrials.gov/study/NCT03773965",
"title": "A Phase 3 Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients From 1 Year to <18 Years of Age With Juvenile Idiopathic Arthritis (JIA)",
"has_exemption": false,
"start_date": "2019-04-05",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05905926",
"publication_url": "https://clinicaltrials.gov/study/NCT05905926",
"title": "An Open-Label Long-Term Safety Study of Tenapanor for the Treatment of Irritable Bowel Syndrome With Constipation (IBS-C) in Pediatric Patients 6 to Less Than 18 Years Old",
"has_exemption": false,
"start_date": "2023-02-17",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ardelyx",
"sponsor_slug": "ardelyx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05864534",
"publication_url": "https://clinicaltrials.gov/study/NCT05864534",
"title": "A Phase 2a Trial of Immune Modulation in Combination With Ultrasound-mediated Blood Brain Barrier Opening in Patients With Newly Diagnosed Glioblastoma",
"has_exemption": false,
"start_date": "2024-01-19",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05952934",
"publication_url": "https://clinicaltrials.gov/study/NCT05952934",
"title": "A Phase II Clinical Trial of Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence",
"has_exemption": false,
"start_date": "2024-02-12",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arkansas",
"sponsor_slug": "university-of-arkansas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06641271",
"publication_url": "https://clinicaltrials.gov/study/NCT06641271",
"title": "Vagus Nerve Stimulation to Promote Remyelination in Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-01-21",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06789913",
"publication_url": "https://clinicaltrials.gov/study/NCT06789913",
"title": "A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation",
"has_exemption": false,
"start_date": "2025-06-13",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Relay Therapeutics, Inc.",
"sponsor_slug": "relay-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899152",
"publication_url": "https://clinicaltrials.gov/study/NCT06899152",
"title": "HepQuant: Pilot Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06948786",
"publication_url": "https://clinicaltrials.gov/study/NCT06948786",
"title": "PROMOTE-FL: Pirtobrutinib and Mosunetuzumab to Enhance Treatment Efficacy for Patients With Relapsed/Refractory Follicular Lymphoma",
"has_exemption": false,
"start_date": "2025-11-17",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07128381",
"publication_url": "https://clinicaltrials.gov/study/NCT07128381",
"title": "Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)",
"has_exemption": false,
"start_date": "2026-01-02",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222137",
"publication_url": "https://clinicaltrials.gov/study/NCT07222137",
"title": "A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Delay Stage 3 Type 1 Diabetes in At-risk Participants Aged ≥1 to <36 Years",
"has_exemption": false,
"start_date": "2026-01-12",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226206",
"publication_url": "https://clinicaltrials.gov/study/NCT07226206",
"title": "A Phase 2b, Single-Arm, Open-Label, Multicenter Study of the Safety of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A",
"has_exemption": false,
"start_date": "2026-07-14",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07232069",
"publication_url": "https://clinicaltrials.gov/study/NCT07232069",
"title": "Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07506512",
"publication_url": "https://clinicaltrials.gov/study/NCT07506512",
"title": "Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy Loss",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07602166",
"publication_url": "https://clinicaltrials.gov/study/NCT07602166",
"title": "Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07655440",
"publication_url": "https://clinicaltrials.gov/study/NCT07655440",
"title": "Comparative Outcomes of Migraine Preventives and Anti-CGRP Therapies for Tinnitus in Patients With Migraine: A Randomized Active-Comparator Controlled Trial (COMPACT-PM)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07661498",
"publication_url": "https://clinicaltrials.gov/study/NCT07661498",
"title": "Indomethacin vs. no Indomethacin for Patients Undergoing Biliary ERCP With Prior Biliary Sphincterotomy",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07673367",
"publication_url": "https://clinicaltrials.gov/study/NCT07673367",
"title": "A Phase 2 Trial of Nemtabrutinib in Combination With Brexu-cel for Patients With Relapsed/Refractory Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174414",
"publication_url": "https://clinicaltrials.gov/study/NCT07174414",
"title": "Cilostazol for Prevention of Recurrent Stroke Trial",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07408583",
"publication_url": "https://clinicaltrials.gov/study/NCT07408583",
"title": "A Phase I/II, Non-Randomized Study of the Safety and Efficacy of In Utero Hematopoietic Stem Cell Transplantation for the Treatment of Fanconi Anemia in Affected Fetuses",
"has_exemption": false,
"start_date": "2028-01-31",
"completion_date": "2031-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Agnieszka Czechowicz",
"sponsor_slug": "agnieszka-czechowicz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06990737",
"publication_url": "https://clinicaltrials.gov/study/NCT06990737",
"title": "Phase 2 Pragmatic Trial Investigating Sentinel Lymph Node Biopsy (SLNB) Efficacy and Safety in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck",
"has_exemption": false,
"start_date": "2025-06-25",
"completion_date": "2031-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06866262",
"publication_url": "https://clinicaltrials.gov/study/NCT06866262",
"title": "Phase I/II Trial of Inulin Gel in Combination With Ipilimumab and Nivolumab in Advanced Renal Cell Carcinoma [ICON Trial]",
"has_exemption": false,
"start_date": "2025-08-15",
"completion_date": "2031-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07043738",
"publication_url": "https://clinicaltrials.gov/study/NCT07043738",
"title": "Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial",
"has_exemption": false,
"start_date": "2026-08-03",
"completion_date": "2031-08-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07063745",
"publication_url": "https://clinicaltrials.gov/study/NCT07063745",
"title": "A Randomized Phase 2/3 Study of Navlimetostat (BMS-986504) in Combination With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion",
"has_exemption": false,
"start_date": "2026-01-02",
"completion_date": "2031-08-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06568172",
"publication_url": "https://clinicaltrials.gov/study/NCT06568172",
"title": "Randomized Phase III Trial of Neoadjuvant Immunotherapy With Response-Adapted Treatment Versus Standard-of-Care Treatment for Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma (C-PRE)",
"has_exemption": false,
"start_date": "2025-02-18",
"completion_date": "2031-08-14",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06940297",
"publication_url": "https://clinicaltrials.gov/study/NCT06940297",
"title": "DART: Phase II Study of Dasatinib and Quercetin in Patients With Relapsed, Refractory Multiple Myeloma Receiving CAR-T Therapy",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2031-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07630974",
"publication_url": "https://clinicaltrials.gov/study/NCT07630974",
"title": "LIGHTBEAM-U01 Substudy 01D: A Phase 1b/2 Substudy to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors",
"has_exemption": false,
"start_date": "2026-07-02",
"completion_date": "2031-08-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07346196",
"publication_url": "https://clinicaltrials.gov/study/NCT07346196",
"title": "A Randomized Phase II Trial of Induction Cemiplimab Plus Chemotherapy With or Without Fianlimab in Locoregionally Advanced Squamous Cell Carcinoma of The Head and Neck",
"has_exemption": false,
"start_date": "2027-02-07",
"completion_date": "2031-08-22",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07509151",
"publication_url": "https://clinicaltrials.gov/study/NCT07509151",
"title": "A Phase III, Randomised, Open-label, Multicentre, Study of Surovatamig as Consolidation Therapy Versus Observation After First-line Induction Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV (SOUNDTRACK-C1)",
"has_exemption": false,
"start_date": "2026-05-05",
"completion_date": "2031-08-29",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05538091",
"publication_url": "https://clinicaltrials.gov/study/NCT05538091",
"title": "Phase II Clinical Trial Combining the Hedgehog Inhibitor Vismodegib With the PD-L1 Inhibitor Atezolizumab in Patients With Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer",
"has_exemption": false,
"start_date": "2023-05-15",
"completion_date": "2031-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ronald Buckanovich",
"sponsor_slug": "ronald-buckanovich",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06922318",
"publication_url": "https://clinicaltrials.gov/study/NCT06922318",
"title": "A Phase II Study of Sequential Bipolar Androgen Therapy and ZEN-3694 in Sequence With Enzalutamide + ZEN-3694 in Asymptomatic Patients With Metastatic CRPC: The COSMYC Trial (COmbined Suppression of MYC)",
"has_exemption": false,
"start_date": "2025-08-19",
"completion_date": "2031-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228221",
"publication_url": "https://clinicaltrials.gov/study/NCT07228221",
"title": "iStent Infinite and iDose TR for Management of Moderate to Severe Primary Open Angle Glaucoma Are a Safe and Effective Alternative to Filtering Surgery for IOP Reduction in Patients With Medically Uncontrolled Glaucoma. (POAG)",
"has_exemption": false,
"start_date": "2026-01-05",
"completion_date": "2031-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonathon Myers",
"sponsor_slug": "jonathon-myers",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00969111",
"publication_url": "https://clinicaltrials.gov/study/NCT00969111",
"title": "Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy",
"has_exemption": false,
"start_date": "2009-08-31",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Proton Collaborative Group",
"sponsor_slug": "proton-collaborative-group",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT04895709",
"publication_url": "https://clinicaltrials.gov/study/NCT04895709",
"title": "A Phase 1/2 Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2021-05-27",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04933721",
"publication_url": "https://clinicaltrials.gov/study/NCT04933721",
"title": "An Open-label Study to Provide Berotralstat Access to Subjects With Type 1 and 2 Hereditary Angioedema Who Were Previously Enrolled in Berotralstat Studies",
"has_exemption": false,
"start_date": "2021-07-23",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioCryst Pharmaceuticals",
"sponsor_slug": "biocryst-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06790784",
"publication_url": "https://clinicaltrials.gov/study/NCT06790784",
"title": "A Randomized Clinical Trial Evaluating Combination Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of Proliferative Diabetic Retinopathy",
"has_exemption": false,
"start_date": "2025-08-04",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jaeb Center for Health Research",
"sponsor_slug": "jaeb-center-for-health-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06441006",
"publication_url": "https://clinicaltrials.gov/study/NCT06441006",
"title": "Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis (PRISM-TB)",
"has_exemption": false,
"start_date": "2025-10-03",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07322146",
"publication_url": "https://clinicaltrials.gov/study/NCT07322146",
"title": "Comparing Two Durations of Antibiotic Treatment for Children Hospitalized With Common Infections",
"has_exemption": false,
"start_date": "2026-02-13",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07725380",
"publication_url": "https://clinicaltrials.gov/study/NCT07725380",
"title": "Open-Label, Cohort-Sequential Dose-Escalation and Dose-Confirmation Phase 1/2 Clinical Trial to Evaluate the Safety and Efficacy of Domatinostat in Combination With Sirolimus in Adolescents and Adults With Relapsed, Refractory Sarcoma and Osteosarcoma",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07558265",
"publication_url": "https://clinicaltrials.gov/study/NCT07558265",
"title": "WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University",
"sponsor_slug": "ohio-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02448173",
"publication_url": "https://clinicaltrials.gov/study/NCT02448173",
"title": "A Randomized Multicenter Study of Active Specific Immunotherapy With OncoVax® in Patients With Stage II Colon Cancer",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vaccinogen Inc",
"sponsor_slug": "vaccinogen-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06639607",
"publication_url": "https://clinicaltrials.gov/study/NCT06639607",
"title": "Phase 1/2 Trial of PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma (PRiME II)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07634562",
"publication_url": "https://clinicaltrials.gov/study/NCT07634562",
"title": "A Phase 1-2 Prospective Study to Evaluate the Safety and Feasibility of Total Lymphoid Irradiation (TLI) and Anti-Thymocyte Globulin (ATG) in Liver Transplantation Recipients to Induce Immune Tolerance",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07605923",
"publication_url": "https://clinicaltrials.gov/study/NCT07605923",
"title": "Methylprednisolone Addition to Multimodal Pain Regimens After Anterior Cruciate Ligament Reconstruction",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05155033",
"publication_url": "https://clinicaltrials.gov/study/NCT05155033",
"title": "Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma",
"has_exemption": false,
"start_date": "2022-08-18",
"completion_date": "2031-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06188741",
"publication_url": "https://clinicaltrials.gov/study/NCT06188741",
"title": "Phase 2 Trial of Selumetinib for the Prevention of Plexiform Neurofibroma Growth and Morbidity in Neurofibromatosis Type 1",
"has_exemption": false,
"start_date": "2025-08-27",
"completion_date": "2031-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07392580",
"publication_url": "https://clinicaltrials.gov/study/NCT07392580",
"title": "A Single-Arm, Open-Label Study of Intralesional Treatment of Laryngeal Squamous Cell Carcinoma With Cisplatin",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2031-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594015",
"publication_url": "https://clinicaltrials.gov/study/NCT07594015",
"title": "Phase 2 Open-Label Trial Investigating the Efficacy and Safety of Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Failure of First-Line Therapy With Platinum-based Doublet and Immunotherapy",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2031-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07649291",
"publication_url": "https://clinicaltrials.gov/study/NCT07649291",
"title": "Duloxetine Plus Exercise to Improve Physical Function in Veterans With Knee Osteoarthritis, Pain, and Psychological Comorbidity",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2031-09-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06833073",
"publication_url": "https://clinicaltrials.gov/study/NCT06833073",
"title": "A Phase 2 Open-label Randomized Study of V940 in Combination With BCG Versus BCG Monotherapy in Participants With High-risk Non-muscle Invasive Bladder Cancer (INTerpath-011)",
"has_exemption": false,
"start_date": "2025-03-11",
"completion_date": "2031-09-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06247995",
"publication_url": "https://clinicaltrials.gov/study/NCT06247995",
"title": "A Phase I/II, Open-label, Multi-center Trial of [177Lu]Lu-NeoB in Combination With Capecitabine in Adult Patients With Gastrin Releasing Peptide Receptor Positive, Estrogen Receptor-positive, Human Epidermal Growth Factor Receptor-2 Negative Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.",
"has_exemption": false,
"start_date": "2024-08-14",
"completion_date": "2031-09-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04929028",
"publication_url": "https://clinicaltrials.gov/study/NCT04929028",
"title": "Risk-Adapted Therapy for HIV-Associated Anal Cancer",
"has_exemption": false,
"start_date": "2022-08-09",
"completion_date": "2031-09-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07498335",
"publication_url": "https://clinicaltrials.gov/study/NCT07498335",
"title": "A Single-arm, Multicenter, Phase III Study to Assess Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients of 2 to <18 Years of Age With Primary Immunoglobulin A Nephropathy (IgAN)",
"has_exemption": false,
"start_date": "2026-08-26",
"completion_date": "2031-09-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02919592",
"publication_url": "https://clinicaltrials.gov/study/NCT02919592",
"title": "MemoryShape® and MemoryGel® Breast Implants Post Approval New Enrollment Study (\"Glow Study\")",
"has_exemption": false,
"start_date": "2016-09-01",
"completion_date": "2031-09-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Mentor Worldwide, LLC",
"sponsor_slug": "mentor-worldwide-llc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05627362",
"publication_url": "https://clinicaltrials.gov/study/NCT05627362",
"title": "A Phase II, Multicenter, Double-Blind, Randomised, Placebo-Controlled Study and Open Label Long Term Extension to Evaluate the Safety and Efficacy of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis (PSC).",
"has_exemption": false,
"start_date": "2022-12-29",
"completion_date": "2031-09-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04245839",
"publication_url": "https://clinicaltrials.gov/study/NCT04245839",
"title": "A Phase 2, Open-label, Single Arm, Multicohort, Multicenter Trial to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)",
"has_exemption": false,
"start_date": "2020-07-14",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Celgene",
"sponsor_slug": "celgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07153796",
"publication_url": "https://clinicaltrials.gov/study/NCT07153796",
"title": "A Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07283679",
"publication_url": "https://clinicaltrials.gov/study/NCT07283679",
"title": "Phase I/II Trial of ONC-PluReceptor NK Cells With Epcoritamab and Tafasitamab for Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-02-24",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07321899",
"publication_url": "https://clinicaltrials.gov/study/NCT07321899",
"title": "Transcatheter Tricuspid Valve Replacement Using the Medtronic Intrepid™ TTVR System in Patients With Severe Symptomatic Tricuspid Regurgitation - PATHFINDER",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiovascular",
"sponsor_slug": "medtronic-cardiovascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07680153",
"publication_url": "https://clinicaltrials.gov/study/NCT07680153",
"title": "Neuromodulation of Mood Switch Circuitry in Bipolar Disorder",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07178912",
"publication_url": "https://clinicaltrials.gov/study/NCT07178912",
"title": "Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)",
"has_exemption": false,
"start_date": "2026-08-27",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07468916",
"publication_url": "https://clinicaltrials.gov/study/NCT07468916",
"title": "Ropeginterferon Alfa-2b for MDS/MPN Overlap Syndromes, Including CMML and MDS/MPN-RS-T",
"has_exemption": false,
"start_date": "2026-09-29",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07660783",
"publication_url": "https://clinicaltrials.gov/study/NCT07660783",
"title": "A Phase II Prospective Study Evaluating Selective Depletion of CD45RA+ (Naïve) T Cells (TND) From Peripheral Blood Stem Cell (PBSC) Grafts for Prevention of Graft Versus Host Disease (GVHD) in Non-Malignant Diseases (NMDs)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07710534",
"publication_url": "https://clinicaltrials.gov/study/NCT07710534",
"title": "Metronomic Decitabine-Cedazuridine and Venetoclax in Relapsed/Refractory Acute Myeloid Leukemia R/R AML), High Risk Myelodysplastic Syndrome (HR-MDS), and High-Risk Myeloproliferative Neoplasms (HR/AP MPN)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07528326",
"publication_url": "https://clinicaltrials.gov/study/NCT07528326",
"title": "TRiCares Topaz Transcatheter Tricuspid Heart Valve Replacement System IDE Pivotal Study",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "TRiCares",
"sponsor_slug": "tricares",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07164469",
"publication_url": "https://clinicaltrials.gov/study/NCT07164469",
"title": "Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-12-28",
"completion_date": "2031-09-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214896",
"publication_url": "https://clinicaltrials.gov/study/NCT07214896",
"title": "HEALTH: Humanoid Evaluation and Learning Trial in Coalition-Aligned Healthcare Settings",
"has_exemption": false,
"start_date": "2025-10-06",
"completion_date": "2031-10-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Truway Health, Inc.",
"sponsor_slug": "truway-health-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07361510",
"publication_url": "https://clinicaltrials.gov/study/NCT07361510",
"title": "ROSETTA Lung-202: A Randomized, Double-Blind, Phase 3 Study of Pumitamig Monotherapy Compared to Pembrolizumab as First-line Treatment in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With PD-L1 ≥ 50%.",
"has_exemption": false,
"start_date": "2026-03-12",
"completion_date": "2031-10-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05624996",
"publication_url": "https://clinicaltrials.gov/study/NCT05624996",
"title": "Phase III Prospective Randomized Trial of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed by Concurrent Mediastinal Chemoradiation for Locally-Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2023-07-12",
"completion_date": "2031-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "NRG Oncology",
"sponsor_slug": "nrg-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07136012",
"publication_url": "https://clinicaltrials.gov/study/NCT07136012",
"title": "A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing Olpasiran Use to Prevent First Major Cardiovascular Events in Participants With Elevated Lipoprotein(a)",
"has_exemption": false,
"start_date": "2025-08-22",
"completion_date": "2031-10-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07660094",
"publication_url": "https://clinicaltrials.gov/study/NCT07660094",
"title": "A Phase 3, Multicenter, Randomized, Controlled, Open-Label Clinical Trial of Aglatimagene Besadenovec (CAN-2409) Plus Prodrug and Pembrolizumab Versus Docetaxel for Stage IV Non-Squamous Non-Small Cell Lung Cancer Progressing on Pembrolizumab-based Treatment",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2031-10-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Candel Therapeutics, Inc.",
"sponsor_slug": "candel-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07013487",
"publication_url": "https://clinicaltrials.gov/study/NCT07013487",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Immunogenicity, and Efficacy of V181 Dengue Vaccine in Healthy Participants 2 to 17 Years of Age",
"has_exemption": false,
"start_date": "2025-06-11",
"completion_date": "2031-10-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07049926",
"publication_url": "https://clinicaltrials.gov/study/NCT07049926",
"title": "A Phase 1b/2 Study of Immune and Targeted Combination Therapies in Participants With RCC (KEYMAKER-U03): Substudy 03C in Participants With Recurrent Disease During or After Anti-PD-(L)1 Adjuvant Therapy",
"has_exemption": false,
"start_date": "2025-07-20",
"completion_date": "2031-10-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07665437",
"publication_url": "https://clinicaltrials.gov/study/NCT07665437",
"title": "A Double-blind, Double-dummy, Parallel Group, Multicenter Phase 3 Extension Study Evaluating the Long-term Safety and Efficacy of 2 Doses of Remibrutinib in Adult Participants With Moderate to Severe Hidradenitis Suppurativa",
"has_exemption": false,
"start_date": "2026-07-10",
"completion_date": "2031-10-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07216703",
"publication_url": "https://clinicaltrials.gov/study/NCT07216703",
"title": "A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab With or Without Bevacizumab Compared With Standard of Care as Firstline Maintenance Treatment for Participants With Persistent, Recurrent, or Newly Diagnosed Metastatic Cervical Cancer With PD-L1 CPS Greater Than or Equal to 1 (TroFuse-036/GOG-3123/ENGOT-cx22)",
"has_exemption": false,
"start_date": "2026-01-19",
"completion_date": "2031-10-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05951179",
"publication_url": "https://clinicaltrials.gov/study/NCT05951179",
"title": "A Phase 2, Open-Label Study to Evaluate the Safety and Efficacy of Intravesical Instillation of TARA-002 in Adults With High-Grade Non-Muscle Invasive Bladder Cancer",
"has_exemption": false,
"start_date": "2023-09-15",
"completion_date": "2031-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Protara Therapeutics",
"sponsor_slug": "protara-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06236438",
"publication_url": "https://clinicaltrials.gov/study/NCT06236438",
"title": "A Randomized, Phase 2/3 Study to Evaluate the Optimal Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2024-04-10",
"completion_date": "2031-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06372964",
"publication_url": "https://clinicaltrials.gov/study/NCT06372964",
"title": "A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Lumateperone for the Treatment of Major Depressive Episodes (MDEs) Associated With Bipolar I or Bipolar II Disorder (Bipolar Depression) in Pediatric Patients Aged 10 to 17 Years",
"has_exemption": false,
"start_date": "2024-05-14",
"completion_date": "2031-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06013423",
"publication_url": "https://clinicaltrials.gov/study/NCT06013423",
"title": "Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults and Pediatrics",
"has_exemption": false,
"start_date": "2024-07-23",
"completion_date": "2031-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06898450",
"publication_url": "https://clinicaltrials.gov/study/NCT06898450",
"title": "A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair",
"has_exemption": false,
"start_date": "2025-03-31",
"completion_date": "2031-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nimbus Wadjet, Inc.",
"sponsor_slug": "nimbus-wadjet-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}