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"title": "Phase II Study of Everolimus (RAD001, Afinitor®) for Children With Recurrent or Progressive Ependymoma",
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"title": "Tandem Autologous Hematopoietic Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma",
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"title": "A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Patients With Moderate-to-Severe Asthma",
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"title": "MyoVista wavECG Clinical Evaluation: >=60 y/o Enrichment Population",
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"title": "A Randomized, Controlled Clinical Investigation of an Improved Two-piece Stoma Product for People Living With a Stoma",
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"title": "Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses",
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"title": "A Phase 2 Open-label, Multicenter, Randomized, Multidrug Platform Study of Durvalumab (MEDI4736) Alone or in Combination With Novel Agents in Subjects With Locally Advanced, Unresectable (Stage III) Non-small Cell Lung Cancer (COAST)",
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"title": "PET MYOCARDIAL Blood Flow Comparison to Coronary CTA and CT-FFR",
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"title": "A Phase 3, Randomized, Active-Controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of Oral Islatravir Once-Monthly as Preexposure Prophylaxis in Cisgender Women at High Risk for HIV-1 Infection",
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"title": "Comparison of Vaginal Dehydroepiandrosterone (DHEA) to Control for Treatment of Vaginal Symptoms in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors: A Phase II Randomized Trial",
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"title": "A Phase 3, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)",
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"title": "A Phase 2 Non-randomized, Open-label, Multi-cohort, Multi-center Study Assessing the Clinical Benefit of SAR444245 (THOR-707) Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Pleural Mesothelioma",
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"registry_id": "NCT05749952",
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"title": "Digital Weight Bearing Shape Capture Socket Technology to Preserve Limb Health and Improve Rehabilitation Outcomes",
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"registry_id": "NCT02939976",
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"title": "Study of Access Site for Enhancing PCI in STEMI for Seniors (SAFE STEMI for Seniors)",
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"title": "A Phase 3, Multicenter, Randomized, Placebo- and Active Comparator-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Subjects (>=6 To <18 Years of Age)",
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"registry_id": "NCT03714828",
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"title": "A Single Arm Phase 2 Study of Talimogene Laherparepvec in Patients With Cutaneous Squamous Cell Cancer",
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"title": "A Phase 3, Multicenter, Randomized, Double-blind Trial of Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder",
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"sponsor_name": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
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"title": "A Randomized, Double-Masked, 48-Week, Parallel-Group, Placebo-Controlled, Proof-of-Concept Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy",
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"title": "A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects With Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment",
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"title": "Limb Health and Socket Pressure in Response to Powered Ankle Prostheses",
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"title": "A Randomized, Multi-Center, Double Blinded, Self-Initiated, Single Treatment Study Comparing Sitavig® (Acyclovir) 50 mg Muco-adhesive Buccal Tablet to Placebo in the Treatment of Herpes Labialis in Immunocompetent Adults",
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"title": "A Randomized, Double-blind, Placebo-controlled, Multi-center, Dose-ranging Phase 2 Study of Rilzabrutinib Followed by an Open-label Extension Phase in Patients With Moderate-to-severe Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite the Use of H1 Antihistamine Treatment",
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"title": "Robotic Exosuit Augmented Locomotion (REAL) in the Clinic and Community - a Mechanistic Clinical Trial",
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"title": "Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening",
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"title": "A Phase Ib/II Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma",
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"title": "Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY3857210 for the Treatment of Diabetic Peripheral Neuropathic Pain",
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"title": "Evaluation of Thermal Outcome and Safety of Nuera Tight RF System",
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"title": "An Open-label, Prospective Trial Assessing Positive Detection Accuracy and Detection Latency Measures of the Miniature Ingestible Event Marker Tablet Using the D-Tect Patch in Healthy Subjects and Assessing Detection Latency Measures Using the D-Tect Patch in Subjects With Serious Mental Illness Taking Abilify MyCite Tablet",
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"title": "A Prospective, Multicenter, Randomized, Controlled Clinical Investigation of MONTAGE in Adults With Spinal Deformity Undergoing Pedicle Subtraction Osteotomy",
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"title": "A Phase III Multi-center, Randomized, Open-label Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET",
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"sponsor_name": "Advanced Accelerator Applications",
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"registry_id": "NCT06438614",
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"title": "A Phase II Single Center Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor (GM CSF and Ifosfamide Carboplatin Etoposide) For Patients With Relapsed Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma",
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"registry_id": "NCT05117060",
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"title": "A Phase 2 Trial to Evaluate the Efficacy and Safety of Orally Administered LEO 152020 Tablets Compared With Placebo Tablets for up to 16 Weeks of Treatment in Adults With Moderate to Severe Atopic Dermatitis",
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"title": "A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABBV-154 in Subjects With Moderately to Severely Active Crohn's Disease (CD): AIM-CD",
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"title": "A Phase 2b Dose Ranging Study to Evaluate the Efficacy and Safety of Rozibafusp Alfa (AMG 570) in Subjects With Active Systemic Lupus Erythematosus (SLE) With Inadequate Response to Standard of Care (SOC) Therapy",
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"title": "Program on Genetic and Dietary Predictors of Drug Response in Rural and AI/AN Populations, Project-3, SA-3, Anti-platelet Response",
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"title": "Bendamustine + Obinutuzumab Induction Chemoimmunotherapy With Risk-adapted Obinutuzumab Maintenance Therapy in Previously Untreated Mantle Cell Lymphoma",
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"title": "Phase II Study Evaluating HSV-tk + Valacyclovir Gene Therapy in Combination With Androgen Deprivation Therapy, Brachytherapy, External Beam Radiotherapy, and Prostatectomy for High-Risk Prostate Cancer",
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"title": "A Phase 1/2a Randomized, Double-Blind, Two-Part, Dose-Ascending, Multicenter Study of the Safety and PK of AR-501 (Gallium Citrate), Administered Via Inhalation, in Healthy Adult and P. Aeruginosa Infected Cystic Fibrosis Subjects",
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"title": "A Phase II Study of TAS-102 in Metastatic Platinum and Checkpoint Inhibitor-resistant Bladder Cancer",
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"title": "A Phase 2 Randomized Double-Blinded Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in Subjects With Indolent Systemic Mastocytosis",
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"title": "LIO-1: A Phase 1b/2, Open-Label Study to Evaluate the Safety and Efficacy of Lucitanib in Combination With Nivolumab in Patients With An Advanced, Metastatic Solid Tumor",
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"title": "A Phase 2/3 Open-Label, Single-Arm Trial to Evaluate the Safety and Activity of Eculizumab in Pediatric Patients With Relapsing Neuromyelitis Optica Spectrum Disorder",
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"title": "An Open Label Randomized Active Controlled Phase II Clinical Study to Assess the Efficacy and Safety of Afuresertib Plus Paclitaxel Versus Paclitaxel in Patients with Platinum-Resistant Ovarian Cancer",
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"title": "Comparison of Meal-Time Dosing of Rapid Acting Insulin Using Carbohydrate Counting vs. Fixed Doses Utilizing Continuous Glucose Monitoring In Patients With Cystic Fibrosis Related Diabetes",
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"title": "Hyperbaric Oxygen Therapy to Prevent Complications After Lower Limb Amputation",
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"title": "Impact of Acute Cannabis Administration on Pain Symptomology and Inflammatory Markers Among Patients With Rheumatoid or Psoriatic Arthritis",
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"title": "The Fat Analysis Trial (FAT): The Impact of Lip-aspirate Processing on Fat Resorption in Autologous Fat Grafting to the Breast: A Randomized Controlled Trial",
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"title": "The Performance of da Vinci SP System on Extraperitoneal Approach Radical Prostatectomy-a Single Arm Pivotal Trial Initiated by Chang Gung Memorial Hospital, Taiwan",
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"registry_id": "NCT05419297",
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"title": "True Functional Restoration and Analgesia in Non-Radicular Low Back Pain: a Prospective, Double Blind, Placebo-controlled Study of Buccal Buprenorphine",
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"title": "A Two-Part Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy of the Anti-Bet v 1 Monoclonal Antibodies to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen",
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"title": "Endocuff Enhanced Colonoscopy: Does it Improve Polyp Detection and Make Rectal Retroflexion Unnecessary",
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"title": "A PHASE 2B, RANDOMIZED, DOUBLE BLIND, VEHICLE CONTROLLED, PARALLEL GROUP STUDY TO ASSESS THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF MULTIPLE DOSE LEVELS OF PF-07038124 OINTMENT FOR 12 WEEKS IN PARTICIPANTS 12 YEARS AND OLDER AND WITH MILD-TO-MODERATE ATOPIC DERMATITIS OR MILD-TO-SEVERE PLAQUE PSORIASIS",
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"title": "Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia: A Randomized Controlled Quadruple Blinded Non-Inferiority Trial (CLASSIER Trial)",
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"title": "Phase II Study to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis",
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"title": "Causal Role of Frontostriatal Circuitry in Goal-directed Behavior",
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"title": "ACTIV-6: COVID-19 Outpatient Randomized Trial to Evaluate Efficacy of Repurposed Medications",
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"start_date": "2023-01-27",
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"title": "A Phase III, Randomized, Multicenter, Parallel-group Clinical Trial for Examining the Therapeutic Equivalence Between Fluticasone Propionate 100 mcg and Salmeterol 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 mcg Inhalation Powder/GSK in Patients With Asthma",
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"title": "Wingate-type Exercise Test to Evaluate the Effect of High Velocity Therapy on Recovery Sensation and Blood Lactate Decline",
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"title": "Characterizing and Comparing the Duration of Local Anesthetic in Dermatologic Surgery",
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"sponsor_name": "Weill Medical College of Cornell University",
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"title": "Safety and Immunogenicity of Concomitant Administration of the Novavax Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: a Four-arm, Double-blind, Non-inferiority Trial",
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"start_date": "2023-03-31",
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"sponsor_name": "Medical University of Vienna",
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"registry_id": "NCT01851369",
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"title": "A Phase I/II Trial of TRC102 (Methoxyamine HCl) in Combination With Temozolomide in Patients With Relapsed Solid Tumors and Lymphomas",
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"start_date": "2013-07-12",
"completion_date": "2023-08-01",
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"sponsor_name": "National Cancer Institute (NCI)",
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"registry_id": "NCT02914600",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02914600",
"title": "A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects With Crohn's Disease",
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"start_date": "2017-03-17",
"completion_date": "2023-08-01",
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"sponsor_name": "Galapagos NV",
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"registry_id": "NCT03381261",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03381261",
"title": "Novel Concepts for OnabotulinumtoxinA (Botox) Mechanisms of Action: Role in Altering the Molecular Environment in Which Pain Fibers Exist",
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"start_date": "2017-12-01",
"completion_date": "2023-08-01",
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"sponsor_name": "Massachusetts General Hospital",
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"registry_id": "NCT03092674",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03092674",
"title": "A Randomized Phase II/III Trial of \"Novel Therapeutics\" Versus Azacitidine in Newly Diagnosed Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS), Age 60 or Older LEAP: Less-Intense AML Platform Trial",
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"start_date": "2018-02-02",
"completion_date": "2023-08-01",
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"sponsor_name": "National Cancer Institute (NCI)",
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"registry_id": "NCT03372460",
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"title": "Combined Transcranial Direct Current Stimulation and Virtual Reality for PTSD",
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"start_date": "2018-04-02",
"completion_date": "2023-08-01",
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"sponsor_name": "VA Office of Research and Development",
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"publication_url": "https://clinicaltrials.gov/ct2/show/NCT02953431",
"title": "Increased Lung Volume as Controller Therapy for Asthma",
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"start_date": "2018-05-07",
"completion_date": "2023-08-01",
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"sponsor_name": "University of Vermont",
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"days_late": 383
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{
"registry_id": "NCT03710603",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03710603",
"title": "A Phase 3 Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) vs VELCADE, Lenalidomide, and Dexamethasone (VRd) in Subjects With Previously Untreated Multiple Myeloma Who Are Eligible for High-dose Therapy",
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"start_date": "2018-12-14",
"completion_date": "2023-08-01",
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"sponsor_name": "Stichting European Myeloma Network",
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"days_late": 31
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{
"registry_id": "NCT03622749",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT03622749",
"title": "Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders",
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"start_date": "2019-03-01",
"completion_date": "2023-08-01",
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"sponsor_name": "Massachusetts General Hospital",
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"registry_id": "NCT04360421",
"publication_url": "https://clinicaltrials.gov/ct2/show/NCT04360421",
"title": "Use of Liposomal Bupivacaine (Exparel) In Expedited Recovery Following Lower Extremity Amputation",
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"start_date": "2020-04-21",
"completion_date": "2023-08-01",
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"sponsor_name": "Loma Linda University",
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"days_late": 383
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"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants With Sickle Cell Disease (HOPE Kids 2)",
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"start_date": "2020-11-11",
"completion_date": "2023-08-01",
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"sponsor_name": "Pfizer",
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