{"recordsFiltered":50028,"recordsTotal":50028,"next":"http://staging-fdaaa.ebmdatalab.net/api/trials/?format=json&length=300&ordering=completion_date&start=35700","previous":"http://staging-fdaaa.ebmdatalab.net/api/trials/?format=json&length=300&ordering=completion_date&start=35100","results":[{"registry_id":"NCT05357690","publication_url":"https://clinicaltrials.gov/study/NCT05357690","title":"Stellate Ganglion Blockade for the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Placebo-Controlled Trial","has_exemption":false,"start_date":"2023-04-19","completion_date":"2026-06-08","has_results":false,"results_due":false,"sponsor_name":"Mayo Clinic","sponsor_slug":"mayo-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06687980","publication_url":"https://clinicaltrials.gov/study/NCT06687980","title":"A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of Dupilumab for the Treatment of Pruritus of Lichen Simplex Chronicus (LSC) in Adults","has_exemption":false,"start_date":"2024-11-25","completion_date":"2026-06-08","has_results":false,"results_due":false,"sponsor_name":"Sanofi","sponsor_slug":"sanofi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06687967","publication_url":"https://clinicaltrials.gov/study/NCT06687967","title":"A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of Dupilumab for the Treatment of Pruritus of Lichen Simplex Chronicus (LSC) in Adults","has_exemption":false,"start_date":"2024-11-28","completion_date":"2026-06-08","has_results":false,"results_due":false,"sponsor_name":"Sanofi","sponsor_slug":"sanofi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06441266","publication_url":"https://clinicaltrials.gov/study/NCT06441266","title":"Pilot Study of Multi-platform Assessment of Radiation Toxicity (M-PART) in Head and Neck Cancer Patients Treated With KeraStat® Cream for Acute Radiation Dermatitis","has_exemption":false,"start_date":"2025-05-08","completion_date":"2026-06-08","has_results":false,"results_due":false,"sponsor_name":"Wake Forest University Health Sciences","sponsor_slug":"wake-forest-university-health-sciences","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07257120","publication_url":"https://clinicaltrials.gov/study/NCT07257120","title":"A Phase IV, Open-label, Single-group Study Evaluating KarXT Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants","has_exemption":false,"start_date":"2026-01-09","completion_date":"2026-06-08","has_results":false,"results_due":false,"sponsor_name":"Karuna Therapeutics, Inc., a Bristol Myers Squibb company","sponsor_slug":"karuna-therapeutics-inc-a-bristol-myers-squibb-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04484818","publication_url":"https://clinicaltrials.gov/study/NCT04484818","title":"A Phase III Double Blinded Study of Early Intervention After RADICAl ProstaTEctomy With Androgen Deprivation Therapy With or Without Darolutamide vs. Placebo in Men at Highest Risk of Prostate Cancer Metastasis by Genomic Stratification (ERADICATE)","has_exemption":false,"start_date":"2021-03-01","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"ECOG-ACRIN Cancer Research Group","sponsor_slug":"ecog-acrin-cancer-research-group","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05021835","publication_url":"https://clinicaltrials.gov/study/NCT05021835","title":"ZEUS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Participants With Established Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease and Systemic Inflammation","has_exemption":false,"start_date":"2021-08-30","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"Novo Nordisk A/S","sponsor_slug":"novo-nordisk-as","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05048797","publication_url":"https://clinicaltrials.gov/study/NCT05048797","title":"An Open-label, Randomized, Multicenter, Phase 3 Study to Assess the Efficacy and Safety of Trastuzumab Deruxtecan as First-line Treatment of Unresectable, Locally Advanced, or Metastatic NSCLC Harboring HER2 Exon 19 or 20 Mutations (DESTINY-Lung04)","has_exemption":false,"start_date":"2021-10-28","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"AstraZeneca","sponsor_slug":"astrazeneca","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05219929","publication_url":"https://clinicaltrials.gov/study/NCT05219929","title":"T4 - Tetracycline Treatment Tolerability Trial A Pilot Study Examining the Feasibility and Tolerability of Tetracycline Therapy in Post-Treatment Lyme Disease (PTLD)","has_exemption":false,"start_date":"2022-11-02","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"Johns Hopkins University","sponsor_slug":"johns-hopkins-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05898074","publication_url":"https://clinicaltrials.gov/study/NCT05898074","title":"Novel Application of RADA16 Hydrogel in Reducing Sinonasal Morbidity After Endoscopic Skull Base Surgery","has_exemption":false,"start_date":"2023-10-09","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"Indiana University","sponsor_slug":"indiana-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06151197","publication_url":"https://clinicaltrials.gov/study/NCT06151197","title":"A Phase 3, Double-blind, Randomized, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis (PFI) (Also Known as Ledderhose Disease)","has_exemption":false,"start_date":"2023-11-28","completion_date":"2026-06-09","has_results":false,"results_due":false,"sponsor_name":"Endo USA Inc., a Keenova Therapeutics Company","sponsor_slug":"endo-usa-inc-a-keenova-therapeutics-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02999009","publication_url":"https://clinicaltrials.gov/study/NCT02999009","title":"A Prospective, Post-market, Multi-center Study of the Trident II Tritanium Acetabular Shell","has_exemption":false,"start_date":"2017-01-20","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Stryker Orthopaedics","sponsor_slug":"stryker-orthopaedics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03263650","publication_url":"https://clinicaltrials.gov/study/NCT03263650","title":"Randomized Phase II Study of Olaparib Maintenance Following Cabazitaxel-Carboplatin Induction Chemotherapy in Men With Aggressive Variant Prostate Cancer (AVPC)","has_exemption":false,"start_date":"2017-10-03","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"M.D. Anderson Cancer Center","sponsor_slug":"md-anderson-cancer-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03945318","publication_url":"https://clinicaltrials.gov/study/NCT03945318","title":"A Phase 1/2, Multicenter Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy","has_exemption":false,"start_date":"2019-04-08","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Novartis Pharmaceuticals","sponsor_slug":"novartis-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03961568","publication_url":"https://clinicaltrials.gov/study/NCT03961568","title":"A Multicenter Open-Label Extension Study to Evaluate the Long-Term Safety of Cenobamate Adjunctive Therapy in Subjects With Primary Generalized Tonic-Clonic Seizures","has_exemption":false,"start_date":"2019-08-13","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"SK Life Science, Inc.","sponsor_slug":"sk-life-science-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05025098","publication_url":"https://clinicaltrials.gov/study/NCT05025098","title":"Precision Therapy Versus Standard Therapy in Acute Myeloid Leukaemia and Myelodysplastic Syndrome in Elderly","has_exemption":false,"start_date":"2021-06-22","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"University Hospital, Akershus","sponsor_slug":"university-hospital-akershus","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05583864","publication_url":"https://clinicaltrials.gov/study/NCT05583864","title":"Lumbar Fusion With Porous Titanium Versus Non-Porous Titanium-Coated PEEK Interbody Cages - A Randomized Controlled Trial","has_exemption":false,"start_date":"2022-11-01","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Francis Farhadi","sponsor_slug":"francis-farhadi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05600777","publication_url":"https://clinicaltrials.gov/study/NCT05600777","title":"A Phase 3, 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Efficacy and Safety Study With Open-label Extension of BLU-5937 in Adult Participants With Refractory Chronic Cough Including Unexplained Chronic Cough (CALM-2)","has_exemption":false,"start_date":"2022-12-05","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Bellus Health Inc. - a GSK company","sponsor_slug":"bellus-health-inc-a-gsk-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05660967","publication_url":"https://clinicaltrials.gov/study/NCT05660967","title":"Efficacy and Safety of Epcoritamab Monotherapy and in Combination With Lenalidomide as First-line Therapy for Anthracycline-ineligible Diffuse Large B-Cell Lymphoma Patients, an Open-label, Randomized, Multicenter, Global Phase 2 Trial","has_exemption":false,"start_date":"2023-03-06","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Genmab","sponsor_slug":"genmab","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06073132","publication_url":"https://clinicaltrials.gov/study/NCT06073132","title":"An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS) [EBShield Study]","has_exemption":false,"start_date":"2024-04-04","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"TWi Biotechnology, Inc.","sponsor_slug":"twi-biotechnology-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07585396","publication_url":"https://clinicaltrials.gov/study/NCT07585396","title":"Efficacy of Inositol in Managing Subfertility in Letrozole-resistant Polycystic Ovary Syndrome Women","has_exemption":false,"start_date":"2024-04-10","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Kafrelsheikh University","sponsor_slug":"kafrelsheikh-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06407934","publication_url":"https://clinicaltrials.gov/study/NCT06407934","title":"A Phase 3, Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group 52-week Extension Study to Evaluate the Treatment Response and Safety of Two Amlitelimab Dose Regimens Administered by Subcutaneous Injection in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis","has_exemption":false,"start_date":"2024-05-08","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Sanofi","sponsor_slug":"sanofi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06290128","publication_url":"https://clinicaltrials.gov/study/NCT06290128","title":"A Phase 3, Double-blind, Placebo-controlled Study Evaluating Efficacy and Safety of Riliprubart in Participants With Refractory Chronic Inflammatory Demyelinating Polyneuropathy","has_exemption":false,"start_date":"2024-07-12","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"Sanofi","sponsor_slug":"sanofi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06799455","publication_url":"https://clinicaltrials.gov/study/NCT06799455","title":"Comparison of Uncuffed Endotracheal Tube to no Endotracheal Tube in EBUS-TBNA Procedure Under Moderate Sedation","has_exemption":false,"start_date":"2025-06-02","completion_date":"2026-06-10","has_results":false,"results_due":false,"sponsor_name":"University of Minnesota","sponsor_slug":"university-of-minnesota","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04350359","publication_url":"https://clinicaltrials.gov/study/NCT04350359","title":"Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder","has_exemption":false,"start_date":"2020-06-08","completion_date":"2026-06-11","has_results":false,"results_due":false,"sponsor_name":"The University of Texas Health Science Center, Houston","sponsor_slug":"the-university-of-texas-health-science-center-houston","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06333015","publication_url":"https://clinicaltrials.gov/study/NCT06333015","title":"A Prospective, Multicenter, Randomized, Controlled Clinical Study to Evaluate the Safety and Effectiveness of the enVista® Beyond (EY) EDF Intraocular Lens in Subjects Undergoing Cataract Extraction","has_exemption":false,"start_date":"2024-08-07","completion_date":"2026-06-11","has_results":false,"results_due":false,"sponsor_name":"Bausch & Lomb Incorporated","sponsor_slug":"bausch-lomb-incorporated","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06584942","publication_url":"https://clinicaltrials.gov/study/NCT06584942","title":"Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder","has_exemption":false,"start_date":"2025-03-10","completion_date":"2026-06-11","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06441604","publication_url":"https://clinicaltrials.gov/study/NCT06441604","title":"Extended-release Buprenorphine as a Novel Low-dose Induction Strategy","has_exemption":false,"start_date":"2025-10-27","completion_date":"2026-06-11","has_results":false,"results_due":false,"sponsor_name":"Brigham and Women's Hospital","sponsor_slug":"brigham-and-womens-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07301385","publication_url":"https://clinicaltrials.gov/study/NCT07301385","title":"Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Feasibility and Safety Study","has_exemption":false,"start_date":"2026-03-11","completion_date":"2026-06-11","has_results":false,"results_due":false,"sponsor_name":"Sharp HealthCare","sponsor_slug":"sharp-healthcare","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05611632","publication_url":"https://clinicaltrials.gov/study/NCT05611632","title":"A Randomized, Controlled Trial to Assess the Clinical Utility of a Multi-cancer Early Detection (MCED) Test for Population Screening in the United Kingdom (UK) When Added to Standard of Care","has_exemption":false,"start_date":"2021-08-31","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"GRAIL, Inc.","sponsor_slug":"grail-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04895696","publication_url":"https://clinicaltrials.gov/study/NCT04895696","title":"A Phase 2, Multicenter, Randomized, Double-blind, Placebo-Controlled, Study to Evaluate the Efficacy and Safety of Afimetoran in Participants With Active Systemic Lupus Erythematosus","has_exemption":false,"start_date":"2021-10-11","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"Beeline Medicines Corporation","sponsor_slug":"beeline-medicines-corporation","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04862650","publication_url":"https://clinicaltrials.gov/study/NCT04862650","title":"A Phase II Trial of the Efficacy and Safety of the Combination of Cemiplimab and Low-Dose Paclitaxel and Carboplatin in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck","has_exemption":false,"start_date":"2021-11-30","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"Marcelo Bonomi","sponsor_slug":"marcelo-bonomi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06347003","publication_url":"https://clinicaltrials.gov/study/NCT06347003","title":"Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults With Severe Hypertriglyceridemia","has_exemption":false,"start_date":"2024-07-22","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"Arrowhead Pharmaceuticals","sponsor_slug":"arrowhead-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06973785","publication_url":"https://clinicaltrials.gov/study/NCT06973785","title":"Non-Narcotic Pain Control After ACL Reconstruction","has_exemption":false,"start_date":"2025-07-15","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"The Cleveland Clinic","sponsor_slug":"the-cleveland-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07052721","publication_url":"https://clinicaltrials.gov/study/NCT07052721","title":"A Randomized, Single-Blinded, Sham-Controlled Study Evaluating the Efficacy and Safety of RELAY, a Device Enabling Both Local Anesthetic Delivery and Neuromodulation Following Shoulder or Foot Surgery","has_exemption":false,"start_date":"2025-09-05","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"University of California, San Diego","sponsor_slug":"university-of-california-san-diego","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07222748","publication_url":"https://clinicaltrials.gov/study/NCT07222748","title":"A Phase 3, Randomized, Double-blind, Comparator- and Placebo-controlled Study to Evaluate the Safety and Efficacy of TLC590 for Postsurgical Pain Management Following Bunionectomy","has_exemption":false,"start_date":"2025-11-17","completion_date":"2026-06-12","has_results":false,"results_due":false,"sponsor_name":"TLC Biopharmaceuticals, Inc.","sponsor_slug":"tlc-biopharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06433219","publication_url":"https://clinicaltrials.gov/study/NCT06433219","title":"An Open-label, Multicenter, Randomized Phase 2 Study of the ATR Inhibitor Tuvusertib in Combination With the PARP Inhibitor Niraparib or the ATM Inhibitor Lartesertib in Participants With BRCA Mutant and/or Homologous Recombination deﬁciency (HRD)-Positive Epithelial Ovarian Cancer That Progressed on Prior PARP Inhibitor Therapy (DDRiver EOC 302)","has_exemption":false,"start_date":"2024-10-30","completion_date":"2026-06-14","has_results":false,"results_due":false,"sponsor_name":"EMD Serono Research & Development Institute, Inc.","sponsor_slug":"emd-serono-research-development-institute-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07051031","publication_url":"https://clinicaltrials.gov/study/NCT07051031","title":"Reactogenicity, Patient Reported Outcomes and Vaccine Preference in Adults Immunized With Recombinant Protein or mRNA COVID-19 Vaccines","has_exemption":false,"start_date":"2025-10-01","completion_date":"2026-06-14","has_results":false,"results_due":false,"sponsor_name":"Marcel Curlin","sponsor_slug":"marcel-curlin","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02214836","publication_url":"https://clinicaltrials.gov/study/NCT02214836","title":"Ultrasound Imaging of Kidney Stones and Lithotripsy","has_exemption":false,"start_date":"2015-01-01","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"University of Washington","sponsor_slug":"university-of-washington","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT03179917","publication_url":"https://clinicaltrials.gov/study/NCT03179917","title":"Pembrolizumab and Involved Site Radiation Therapy for Early Stage Relapsed or Primary Refractory Hodgkin Lymphoma","has_exemption":false,"start_date":"2017-06-08","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Memorial Sloan Kettering Cancer Center","sponsor_slug":"memorial-sloan-kettering-cancer-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03978767","publication_url":"https://clinicaltrials.gov/study/NCT03978767","title":"Preeclampsia And Nonsteroidal Drugs for Analgesia (PANDA): a Randomized Non Inferiority Trial","has_exemption":false,"start_date":"2019-06-10","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Washington University School of Medicine","sponsor_slug":"washington-university-school-of-medicine","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03527537","publication_url":"https://clinicaltrials.gov/study/NCT03527537","title":"Gestational Diabetes and Pharmacotherapy (GAP) - A Randomized Controlled Trial Investigating Timing of Pharmacotherapy Initiation for Patients With Gestational Diabetes","has_exemption":false,"start_date":"2021-05-04","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Medical College of Wisconsin","sponsor_slug":"medical-college-of-wisconsin","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05298423","publication_url":"https://clinicaltrials.gov/study/NCT05298423","title":"Open-label Phase 3 Study of MK-7684A (Coformulation of Vibostolimab With Pembrolizumab) in Combination With Concurrent Chemoradiotherapy Followed by MK-7684A Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Unresectable, Locally Advanced, Stage III NSCLC","has_exemption":false,"start_date":"2022-05-03","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Merck Sharp & Dohme LLC","sponsor_slug":"merck-sharp-dohme-llc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05375994","publication_url":"https://clinicaltrials.gov/study/NCT05375994","title":"A Phase 1/2 Study of Avutometinib (VS-6766) in Combination With Adagrasib in Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC) (RAMP 204)","has_exemption":false,"start_date":"2022-08-01","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Verastem, Inc.","sponsor_slug":"verastem-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05435014","publication_url":"https://clinicaltrials.gov/study/NCT05435014","title":"Phase I/II Randomized, Double-Blind, First-in-Human Study of T-ACE Oil by Trans-Catheter Arterial Embolization or ChemoEmbolization (TAE/TACE) in Patients With Hepatocellular Carcinoma","has_exemption":false,"start_date":"2022-09-13","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"T-ACE Medical Co., Ltd","sponsor_slug":"t-ace-medical-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05953480","publication_url":"https://clinicaltrials.gov/study/NCT05953480","title":"A Phase 2b, Multinational, Randomized, Double-blind Study to Investigate the Efficacy and Safety of Redasemtide (S-005151) Compared With Placebo in Adult Participants With Acute Ischemic Stroke","has_exemption":false,"start_date":"2023-07-14","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Shionogi","sponsor_slug":"shionogi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06504446","publication_url":"https://clinicaltrials.gov/study/NCT06504446","title":"A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Taplucainium Inhalation Powder (NOC-110) in Adults With Refractory or Unexplained Chronic Cough","has_exemption":false,"start_date":"2024-09-24","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Nocion Therapeutics","sponsor_slug":"nocion-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06742281","publication_url":"https://clinicaltrials.gov/study/NCT06742281","title":"A Phase 2b, Randomized, Double-blind, Active-controlled Study of Single Dose CVXGA (CVXGA50) Intranasal COVID-19 Vaccine in Adults","has_exemption":false,"start_date":"2024-12-05","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"CyanVac LLC","sponsor_slug":"cyanvac-llc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06926933","publication_url":"https://clinicaltrials.gov/study/NCT06926933","title":"An Open Label, Single-group, Multicenter Study on the Efficacy and Safety of Leuprolide Acetate 45 mg for Injectable Suspension-controlled Release in Subjects With Central (Gonadotropin-dependent) Precocious Puberty","has_exemption":false,"start_date":"2024-12-12","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"HanAll BioPharma Co., Ltd.","sponsor_slug":"hanall-biopharma-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06780852","publication_url":"https://clinicaltrials.gov/study/NCT06780852","title":"A Pilot Clinical Study to Evidence Improved Cranial Flap Fixation With a Bioresorbable Bone Adhesive Based on Imaging and Patient Reported Outcomes","has_exemption":false,"start_date":"2025-01-15","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"RevBio","sponsor_slug":"revbio","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06849544","publication_url":"https://clinicaltrials.gov/study/NCT06849544","title":"Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection (Zopocianine), a Prostate-Specific Membrane Antigen (PSMA)-Targeted Fluorescent Agent, for the Intraoperative Imaging of Prostate Cancer","has_exemption":false,"start_date":"2025-04-02","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Clinton Bahler","sponsor_slug":"clinton-bahler","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07290400","publication_url":"https://clinicaltrials.gov/study/NCT07290400","title":"Phase 2 Crossover Study Assessing the Effect of Moderate Alcohol Intake on the Absorption and Onset of Action of Hezkue® Sildenafil Oral Suspension","has_exemption":false,"start_date":"2026-04-15","completion_date":"2026-06-15","has_results":false,"results_due":false,"sponsor_name":"Aspargo Labs, Inc","sponsor_slug":"aspargo-labs-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04879940","publication_url":"https://clinicaltrials.gov/study/NCT04879940","title":"Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization in Patients With Localized Prostate Carcinoma and Obstructive Lower Urinary Tract Symptoms","has_exemption":false,"start_date":"2022-02-23","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"H. Lee Moffitt Cancer Center and Research Institute","sponsor_slug":"h-lee-moffitt-cancer-center-and-research-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05425940","publication_url":"https://clinicaltrials.gov/study/NCT05425940","title":"A Randomized Open-Label Phase 3 Study of XL092 + Atezolizumab vs Regorafenib in Subjects With Metastatic Colorectal Cancer","has_exemption":false,"start_date":"2022-09-07","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"Exelixis","sponsor_slug":"exelixis","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05929079","publication_url":"https://clinicaltrials.gov/study/NCT05929079","title":"A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight: A Randomized Double-Blind, Placebo-Controlled Trial","has_exemption":false,"start_date":"2023-07-11","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"Eli Lilly and Company","sponsor_slug":"eli-lilly-and-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06383403","publication_url":"https://clinicaltrials.gov/study/NCT06383403","title":"A Phase IIIb Randomised, Parallel-Group, Double-Blind, Placebo-Controlled, Two-Arm Study to Evaluate the Effect of Elafibranor 80 mg on Normalisation of Alkaline Phosphatase in Adult Participants With Primary Biliary Cholangitis (PBC) and Inadequate Response or Intolerance to Ursodeoxycholic Acid.","has_exemption":false,"start_date":"2024-07-09","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"Ipsen","sponsor_slug":"ipsen","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06560684","publication_url":"https://clinicaltrials.gov/study/NCT06560684","title":"A PHASE 2 CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR-BASED PREP EVALUATING EXTENDED SAFETY, ACCEPTABILITY, AND PHARMACOKINETICS/PHARMACODYNAMICS","has_exemption":false,"start_date":"2024-10-29","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","sponsor_slug":"national-institute-of-allergy-and-infectious-diseases-niaid","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07089706","publication_url":"https://clinicaltrials.gov/study/NCT07089706","title":"A Phase 3b/4, Open-label Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Vaccine Formulations","has_exemption":false,"start_date":"2025-07-21","completion_date":"2026-06-16","has_results":false,"results_due":false,"sponsor_name":"ModernaTX, Inc.","sponsor_slug":"modernatx-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03476681","publication_url":"https://clinicaltrials.gov/study/NCT03476681","title":"Phase 1/2 With Expansion Cohorts in a Study of NEO-201 in Adults With Chemo-Resistant Solid Tumors","has_exemption":false,"start_date":"2019-01-18","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Precision Biologics, Inc","sponsor_slug":"precision-biologics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03888105","publication_url":"https://clinicaltrials.gov/study/NCT03888105","title":"An Open-Label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 x Anti-CD3 Bispecific Antibody, in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma","has_exemption":false,"start_date":"2019-11-13","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Regeneron Pharmaceuticals","sponsor_slug":"regeneron-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04457284","publication_url":"https://clinicaltrials.gov/study/NCT04457284","title":"A Phase II Study of Temozolomide, Cisplatin and Nivolumab in MMR-Proficient Colorectal Cancer","has_exemption":false,"start_date":"2020-11-18","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Memorial Sloan Kettering Cancer Center","sponsor_slug":"memorial-sloan-kettering-cancer-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04768972","publication_url":"https://clinicaltrials.gov/study/NCT04768972","title":"A Phase 1-3 Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION363 in Amyotrophic Lateral Sclerosis Patients With Fused in Sarcoma Mutations (FUS-ALS)","has_exemption":false,"start_date":"2021-06-14","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Ionis Pharmaceuticals, Inc.","sponsor_slug":"ionis-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04925544","publication_url":"https://clinicaltrials.gov/study/NCT04925544","title":"Phase 2, Open-label, Clinical Trial of a Novel Small Molecule EBNA1 Inhibitor, VK 2019, in Patients With Epstein Barr Virus Positive Nasopharyngeal Cancer (NPC) and Other EBV-associated Cancers, With Pharmacokinetic and Pharmacodynamic Correlative Studies","has_exemption":false,"start_date":"2022-01-25","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Stanford University","sponsor_slug":"stanford-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06347016","publication_url":"https://clinicaltrials.gov/study/NCT06347016","title":"Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozsiran in Adults With Severe Hypertriglyceridemia","has_exemption":false,"start_date":"2024-07-23","completion_date":"2026-06-17","has_results":false,"results_due":false,"sponsor_name":"Arrowhead Pharmaceuticals","sponsor_slug":"arrowhead-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04567550","publication_url":"https://clinicaltrials.gov/study/NCT04567550","title":"A Phase 2, Randomized, Controlled, Dose-escalation Study to Evaluate the Efficacy, Safety, and Tolerability of RGX-314 Gene Therapy Delivered Via a Single Suprachoroidal Space (SCS) Injections in Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME)(ALTITUDE)","has_exemption":false,"start_date":"2020-11-20","completion_date":"2026-06-18","has_results":false,"results_due":false,"sponsor_name":"AbbVie","sponsor_slug":"abbvie","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03311451","publication_url":"https://clinicaltrials.gov/study/NCT03311451","title":"Clinical Trial To Evaluate Safety and Efficacy of the C2 CyroBalloon™ 180 Ablation System for the Treatment of Dysplastic Barrett's Esophagus: CBAS180 De-escalation Study","has_exemption":false,"start_date":"2023-01-16","completion_date":"2026-06-18","has_results":false,"results_due":false,"sponsor_name":"Merit Medical Systems, Inc.","sponsor_slug":"merit-medical-systems-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05747534","publication_url":"https://clinicaltrials.gov/study/NCT05747534","title":"Phase 2a Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Larazotide (AT1001) for the Treatment of Long COVID in Children and Adults","has_exemption":false,"start_date":"2023-05-31","completion_date":"2026-06-18","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05432895","publication_url":"https://clinicaltrials.gov/study/NCT05432895","title":"Dynamic Versus Static Night Splinting of Plantar Fasciitis","has_exemption":false,"start_date":"2023-10-31","completion_date":"2026-06-18","has_results":false,"results_due":false,"sponsor_name":"Stanford University","sponsor_slug":"stanford-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07706491","publication_url":"https://clinicaltrials.gov/study/NCT07706491","title":"A Uresta Bladder Support Handle Comparison Study","has_exemption":false,"start_date":"2026-04-20","completion_date":"2026-06-18","has_results":false,"results_due":false,"sponsor_name":"Resilia Inc.","sponsor_slug":"resilia-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03891446","publication_url":"https://clinicaltrials.gov/study/NCT03891446","title":"An Extension Trial to Evaluate the Long-term Safety and Efficacy of Bimatoprost SR in Patients With Open Angle Glaucoma or Ocular Hypertension","has_exemption":false,"start_date":"2019-03-27","completion_date":"2026-06-19","has_results":false,"results_due":false,"sponsor_name":"AbbVie","sponsor_slug":"abbvie","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05217446","publication_url":"https://clinicaltrials.gov/study/NCT05217446","title":"A PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF ENCORAFENIB AND CETUXIMAB PLUS PEMBROLIZUMAB VERSUS PEMBROLIZUMAB ALONE IN PARTICIPANTS WITH PREVIOUSLY UNTREATED BRAF V600E-MUTANT, MSI H/DMMR METASTATIC COLORECTAL CANCER","has_exemption":false,"start_date":"2022-07-11","completion_date":"2026-06-19","has_results":false,"results_due":false,"sponsor_name":"Pfizer","sponsor_slug":"pfizer","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06425302","publication_url":"https://clinicaltrials.gov/study/NCT06425302","title":"A Phase 2 Randomized, Open Label Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma","has_exemption":false,"start_date":"2024-08-30","completion_date":"2026-06-19","has_results":false,"results_due":false,"sponsor_name":"Celgene","sponsor_slug":"celgene","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06632418","publication_url":"https://clinicaltrials.gov/study/NCT06632418","title":"A Randomized Controlled Trial Evaluating the Safety and Feasibility of the Recombinant Human Platelet-derived Growth Factor B (rhPDGF-BB)-Enhanced Collagen Plug for Complex Perianal Fistula Healing","has_exemption":false,"start_date":"2024-11-25","completion_date":"2026-06-19","has_results":false,"results_due":false,"sponsor_name":"Alexander Hawkins","sponsor_slug":"alexander-hawkins","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07491640","publication_url":"https://clinicaltrials.gov/study/NCT07491640","title":"Dynamic Effect of Occlusal Vertical Dimension on Lower Facial Form and Lip Positions","has_exemption":false,"start_date":"2026-03-30","completion_date":"2026-06-19","has_results":false,"results_due":false,"sponsor_name":"The University of Texas Health Science Center, Houston","sponsor_slug":"the-university-of-texas-health-science-center-houston","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03508752","publication_url":"https://clinicaltrials.gov/study/NCT03508752","title":"Phase I/II Trial to Determine the Neurocognitive Decline in Patients With Multiple (>6) Brain Metastases Treated With Distributed Stereotactic Radiosurgery","has_exemption":false,"start_date":"2017-12-05","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"University of Texas Southwestern Medical Center","sponsor_slug":"university-of-texas-southwestern-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04426214","publication_url":"https://clinicaltrials.gov/study/NCT04426214","title":"Neuromodulation and Cognitive Training for Substance Use Disorders","has_exemption":false,"start_date":"2021-07-16","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"University of Minnesota","sponsor_slug":"university-of-minnesota","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05335434","publication_url":"https://clinicaltrials.gov/study/NCT05335434","title":"A Single Center Pilot Study of Intraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis in Patients Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation","has_exemption":false,"start_date":"2022-06-10","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"Dana-Farber Cancer Institute","sponsor_slug":"dana-farber-cancer-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05757219","publication_url":"https://clinicaltrials.gov/study/NCT05757219","title":"A Phase 2, Single-Arm, Open-Label Study Using Itacitinib as Pre-Modulation in Patients With Diffuse Large B-Cell Lymphoma (DLBCL) Receiving CAR-T-Cell Therapy","has_exemption":false,"start_date":"2023-05-19","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"H. Lee Moffitt Cancer Center and Research Institute","sponsor_slug":"h-lee-moffitt-cancer-center-and-research-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05843578","publication_url":"https://clinicaltrials.gov/study/NCT05843578","title":"A Phase 2a, Randomized, Placebo-controlled, Double-blind Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AGMB-129 in Patients With Fibrostenotic Crohn's Disease","has_exemption":false,"start_date":"2023-08-01","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"Agomab Spain S.L.U.","sponsor_slug":"agomab-spain-slu","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06933472","publication_url":"https://clinicaltrials.gov/study/NCT06933472","title":"A Randomized, Double-Blind, Multi-Regional, Phase 3 Study to Evaluate the Efficacy and Safety of AP301 on Serum Phosphorus Control in Chronic Kidney Disease Patients Receiving Maintenance Dialysis With Hyperphosphatemia","has_exemption":false,"start_date":"2025-06-13","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"Alebund Pharmaceuticals","sponsor_slug":"alebund-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07006311","publication_url":"https://clinicaltrials.gov/study/NCT07006311","title":"Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol: A Single-center Pilot Study.","has_exemption":false,"start_date":"2025-08-14","completion_date":"2026-06-20","has_results":false,"results_due":false,"sponsor_name":"University of Zurich","sponsor_slug":"university-of-zurich","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02952508","publication_url":"https://clinicaltrials.gov/study/NCT02952508","title":"An Open-Label, Multicenter, Phase 2 Study of Iopofosine I 131 (CLR 131) in Patients With Relapsed or Refractory (R/R) Select B-Cell Malignancies (CLOVER-1) and Expansion Cohort in Patients With Waldenstrom Macroglobulinemia (CLOVER-WaM)","has_exemption":false,"start_date":"2017-07-26","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Cellectar Biosciences, Inc.","sponsor_slug":"cellectar-biosciences-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03584165","publication_url":"https://clinicaltrials.gov/study/NCT03584165","title":"A Long-term Follow-up Study to Evaluate the Safety and Efficacy of Retinal Gene Therapy in Subjects With Choroideremia Previously Treated With Adeno-Associated Viral Vector Encoding Rab Escort Protein-1 (AAV2-REP1) and in Subjects With X-Linked Retinitis Pigmentosa Previously Treated With Adeno-Associated Viral Vector Encoding RPGR (AAV8-RPGR) in an Antecedent Study","has_exemption":false,"start_date":"2018-06-04","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"NightstaRx Ltd, a Biogen Company","sponsor_slug":"nightstarx-ltd-a-biogen-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04336722","publication_url":"https://clinicaltrials.gov/study/NCT04336722","title":"A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children With Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy","has_exemption":false,"start_date":"2020-07-08","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Albireo, an Ipsen Company","sponsor_slug":"albireo-an-ipsen-company","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05346354","publication_url":"https://clinicaltrials.gov/study/NCT05346354","title":"A Phase 2/3, Open-label, Historical-controlled, Single-arm, Multicenter Study to Evaluate the Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety of Ravulizumab in Children and Adolescents With Aquaporin-4 Antibody Positive (AQP4-Ab [+]) Neuromyelitis Optica Spectrum Disorder (NMOSD)","has_exemption":false,"start_date":"2022-06-23","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Alexion Pharmaceuticals, Inc.","sponsor_slug":"alexion-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04886531","publication_url":"https://clinicaltrials.gov/study/NCT04886531","title":"An Open Label, Phase II Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Cancers Hoosier Cancer Research Network BRE17-141","has_exemption":false,"start_date":"2022-07-21","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Ruth O'Regan","sponsor_slug":"ruth-oregan","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06470763","publication_url":"https://clinicaltrials.gov/study/NCT06470763","title":"A First-in-human, Open-label, Multicenter Phase I/II Study to Evaluate the Safety and Anti-tumor Activity of ANV600 as Single Agent and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (EXPAND-1)","has_exemption":false,"start_date":"2024-07-01","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Anaveon AG","sponsor_slug":"anaveon-ag","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06710847","publication_url":"https://clinicaltrials.gov/study/NCT06710847","title":"A Phase 1/2 First-Time-in-Human, Open-label, Multicenter, Dose Escalation and Expansion Study of the Oral DNA Helicase Werner Inhibitor (WRNi) GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Adult Participants With Mismatch Repair-deficient (dMMR) or Microsatellite Instability-High (MSI-H) Solid Tumors (SYLVER)","has_exemption":false,"start_date":"2024-12-13","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"GlaxoSmithKline","sponsor_slug":"glaxosmithkline","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07282860","publication_url":"https://clinicaltrials.gov/study/NCT07282860","title":"A Randomized, Controlled Crossover Study on the Safety, Efficacy, and Patient Reported Outcome Measures Comparing the PureWick™ System With an Established Comparator Overnight in the Home Setting for Incontinence in Adult Males","has_exemption":false,"start_date":"2025-11-21","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"C. R. Bard","sponsor_slug":"c-r-bard","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07560150","publication_url":"https://clinicaltrials.gov/study/NCT07560150","title":"Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers: A Single-Center Randomized, Double-Blinded, Two-Treatment, Two-Period, Two-Sequence, Crossover, Hyperinsulinemia-Euglycemic Clamp Study","has_exemption":false,"start_date":"2026-04-06","completion_date":"2026-06-22","has_results":false,"results_due":false,"sponsor_name":"Amphastar Pharmaceuticals, Inc.","sponsor_slug":"amphastar-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03785249","publication_url":"https://clinicaltrials.gov/study/NCT03785249","title":"A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation KRYSTAL-1","has_exemption":false,"start_date":"2019-01-15","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Mirati Therapeutics Inc.","sponsor_slug":"mirati-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03332238","publication_url":"https://clinicaltrials.gov/study/NCT03332238","title":"A Phase II Study to Evaluate Autologous Stromal Vascular Fraction Cell Therapy to Improve the Repair of Chronically Rotator Cuff Tears","has_exemption":false,"start_date":"2019-07-01","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Hospital for Special Surgery, New York","sponsor_slug":"hospital-for-special-surgery-new-york","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04262843","publication_url":"https://clinicaltrials.gov/study/NCT04262843","title":"Phase II Study of Evaluating the Efficacy of Total Marrow and Lymphoid Irradiation (TMLI) as the Conditioning Regimen for HLA-Haploidentical Hematopoietic Cell Transplantation in Patients With Myelodysplasia or Acute Leukemia","has_exemption":false,"start_date":"2020-02-07","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"City of Hope Medical Center","sponsor_slug":"city-of-hope-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05627635","publication_url":"https://clinicaltrials.gov/study/NCT05627635","title":"A Phase I/II Clinical Trial of FOLFOX Bevacizumab Plus Botensilimab and Balstilimab (3B-FOLFOX) in Patients With MSS Metastatic Colorectal Cancer","has_exemption":false,"start_date":"2023-05-03","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"City of Hope Medical Center","sponsor_slug":"city-of-hope-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05994846","publication_url":"https://clinicaltrials.gov/study/NCT05994846","title":"The Reynolds Innovative Spinal Electrical Stimulation Program: Transcutaneous Stimulation (RISES-T 2.0)","has_exemption":false,"start_date":"2023-06-23","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Thomas Jefferson University","sponsor_slug":"thomas-jefferson-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05966480","publication_url":"https://clinicaltrials.gov/study/NCT05966480","title":"A Phase 2, Multicenter, Multinational, Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety, Efficacy, and Pharmacokinetics of Multiple Dose Levels of ESK-001 in Adult Patients With Systemic Lupus Erythematosus","has_exemption":false,"start_date":"2023-06-26","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Alumis Inc","sponsor_slug":"alumis-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06266130","publication_url":"https://clinicaltrials.gov/study/NCT06266130","title":"A Randomized, Controlled, Two-arm Clinical Study to Evaluate Clinical Efficiency of 3MTM Digital Bonding Versus Direct Bonding","has_exemption":false,"start_date":"2024-03-25","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Solventum Orthodontics Corporation","sponsor_slug":"solventum-orthodontics-corporation","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06643481","publication_url":"https://clinicaltrials.gov/study/NCT06643481","title":"A Phase 2, Randomized, Double-blind, Placebo-controlled Parallel Group Study of VHB937 in Amyotrophic Lateral Sclerosis (ALS) Over 40 Weeks Followed by an Open Label Extension (ASTRALS)","has_exemption":false,"start_date":"2024-10-17","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Novartis Pharmaceuticals","sponsor_slug":"novartis-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07179627","publication_url":"https://clinicaltrials.gov/study/NCT07179627","title":"Powered Ankle Exoskeleton for Stroke Survivors With Gait Impairment","has_exemption":false,"start_date":"2026-02-09","completion_date":"2026-06-23","has_results":false,"results_due":false,"sponsor_name":"Georgia Institute of Technology","sponsor_slug":"georgia-institute-of-technology","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02710253","publication_url":"https://clinicaltrials.gov/study/NCT02710253","title":"Phase II Trial of Salvage Radiation Therapy to Induce Systemic Disease Regression After Progression on Systemic Immunotherapy","has_exemption":false,"start_date":"2016-05-25","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"M.D. Anderson Cancer Center","sponsor_slug":"md-anderson-cancer-center","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT04018872","publication_url":"https://clinicaltrials.gov/study/NCT04018872","title":"A Phase II Trial Evaluating the Effectiveness of Itraconazole in Improving Pathologic Complete Response Rates in Patients With Esophageal Cancer Through Inhibition of the Hedgehog and AKT Signaling Pathways","has_exemption":false,"start_date":"2019-06-24","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"Dallas VA Medical Center","sponsor_slug":"dallas-va-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04240626","publication_url":"https://clinicaltrials.gov/study/NCT04240626","title":"Multimodal Analgesia Effect on Post Surgical Patient","has_exemption":false,"start_date":"2021-01-20","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"University of California, Davis","sponsor_slug":"university-of-california-davis","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05132361","publication_url":"https://clinicaltrials.gov/study/NCT05132361","title":"A Prospective Randomized Multicenter Single Blinded Study to Assess the Safety and Efficacy of the SELUTION SLR™ 018 Drug Eluting Balloon in the Treatment of Subjects With Femoropopliteal Artery Lesions","has_exemption":false,"start_date":"2022-12-01","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"M.A. Med Alliance S.A.","sponsor_slug":"ma-med-alliance-sa","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05671757","publication_url":"https://clinicaltrials.gov/study/NCT05671757","title":"Targeting CD38 With Daratumumab in Primary Antiphospholipid Syndrome: A Phase 1b Dose Escalation Safety Trial (ITN093AI)","has_exemption":false,"start_date":"2023-05-26","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","sponsor_slug":"national-institute-of-allergy-and-infectious-diseases-niaid","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06395753","publication_url":"https://clinicaltrials.gov/study/NCT06395753","title":"A Phase 2, Randomized, Open-Label, Dose-Finding Study of Debio 4228, an Extended-Release Formulation of Gonadotropin-Releasing Hormone Antagonist in Participants With Advanced Prostate Cancer","has_exemption":false,"start_date":"2024-05-23","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"Debiopharm International SA","sponsor_slug":"debiopharm-international-sa","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06596135","publication_url":"https://clinicaltrials.gov/study/NCT06596135","title":"Open-Label Extension Study of Setmelanotide in Patients With a Rare Genetic, Syndromic or Acquired Disease of the MC4R Pathway","has_exemption":false,"start_date":"2024-10-21","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"Rhythm Pharmaceuticals, Inc.","sponsor_slug":"rhythm-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07037420","publication_url":"https://clinicaltrials.gov/study/NCT07037420","title":"A Phase 2, Randomized, Double-blinded, Placebo-controlled, Dose Range-finding, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ALXN2420, a Growth Hormone Receptor Antagonist, Administered Subcutaneously in Combination With Somatostatin Analogs in Adult Participants With Acromegaly","has_exemption":false,"start_date":"2025-10-28","completion_date":"2026-06-24","has_results":false,"results_due":false,"sponsor_name":"Alexion Pharmaceuticals, Inc.","sponsor_slug":"alexion-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04945707","publication_url":"https://clinicaltrials.gov/study/NCT04945707","title":"A Double-blind,Randomized, Placebo-controlled Study to Assess Exercise Tolerance After Iron Repletion With Ferric Derisomaltose (Monoferric®) IV Compared to Placebo in Heart Failure With Preserved Ejection Fraction and With Iron Deficiency.","has_exemption":false,"start_date":"2021-11-26","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04316546","publication_url":"https://clinicaltrials.gov/study/NCT04316546","title":"A Multi-Cohort Phase 2 Dose-Escalation Study of MK-7075 (Miransertib) in Proteus Syndrome","has_exemption":false,"start_date":"2022-05-20","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"National Human Genome Research Institute (NHGRI)","sponsor_slug":"national-human-genome-research-institute-nhgri","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05387551","publication_url":"https://clinicaltrials.gov/study/NCT05387551","title":"Effect of Adding Continuous Glucose Monitoring (CGM) to Lifestyle Changes on Insulin Sensitivity in Patients With Impaired Glucose Tolerance","has_exemption":false,"start_date":"2022-12-01","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Nemours Children's Clinic","sponsor_slug":"nemours-childrens-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06285695","publication_url":"https://clinicaltrials.gov/study/NCT06285695","title":"Clareon Toric Single Arm Study (T2-T9)","has_exemption":false,"start_date":"2024-04-10","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Alcon Research","sponsor_slug":"alcon-research","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06696170","publication_url":"https://clinicaltrials.gov/study/NCT06696170","title":"Initial Safety and Performance of the CellFX® Nano-PFA 360 Catheter Endocardial Ablation System for the Treatment of Atrial Fibrillation","has_exemption":false,"start_date":"2024-07-25","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Pulse Biosciences, Inc.","sponsor_slug":"pulse-biosciences-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06588491","publication_url":"https://clinicaltrials.gov/study/NCT06588491","title":"KYSA-8: A Phase 2 Open-Label, Single-Arm, Multicenter Study of KYV-101, an Autologous Fully Human Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome","has_exemption":false,"start_date":"2024-09-25","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Kyverna Therapeutics","sponsor_slug":"kyverna-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06785012","publication_url":"https://clinicaltrials.gov/study/NCT06785012","title":"A Randomized, Double-blind, Multicenter, Placebo-controlled, Proof-of-Concept Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-89495120 as Monotherapy in Adult Participants With Major Depressive Disorder (MDD)","has_exemption":false,"start_date":"2024-12-26","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Janssen Research & Development, LLC","sponsor_slug":"janssen-research-development-llc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06944639","publication_url":"https://clinicaltrials.gov/study/NCT06944639","title":"Comparative Analysis of Three Types of Collagen Membranes Exposed to the Oral Environment: a Randomized Clinical Trial","has_exemption":false,"start_date":"2025-04-28","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Andrea Ravida","sponsor_slug":"andrea-ravida","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07220356","publication_url":"https://clinicaltrials.gov/study/NCT07220356","title":"C-Raven: Pilot RCT of an Avatar-delivered Computerized Intervention for Tobacco Cessation With Community Health Worker Linkage to Lung Cancer Screening in Baltimore City (FY26)","has_exemption":false,"start_date":"2025-12-10","completion_date":"2026-06-25","has_results":false,"results_due":false,"sponsor_name":"Johns Hopkins University","sponsor_slug":"johns-hopkins-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04505436","publication_url":"https://clinicaltrials.gov/study/NCT04505436","title":"A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate Efficacy, Safety and Tolerability of HM15211(Efocipegtrutide) Treatment for 12 Months in Subjects With Biopsy Confirmed NASH","has_exemption":false,"start_date":"2020-07-31","completion_date":"2026-06-26","has_results":false,"results_due":false,"sponsor_name":"Hanmi Pharmaceutical Company Limited","sponsor_slug":"hanmi-pharmaceutical-company-limited","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03306615","publication_url":"https://clinicaltrials.gov/study/NCT03306615","title":"Peripheral Modulation of Muscle Stiffness and Spasticity","has_exemption":false,"start_date":"2021-10-11","completion_date":"2026-06-26","has_results":false,"results_due":false,"sponsor_name":"Johns Hopkins University","sponsor_slug":"johns-hopkins-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06257537","publication_url":"https://clinicaltrials.gov/study/NCT06257537","title":"Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis","has_exemption":false,"start_date":"2024-10-01","completion_date":"2026-06-26","has_results":false,"results_due":false,"sponsor_name":"ZetrOZ, Inc.","sponsor_slug":"zetroz-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06683638","publication_url":"https://clinicaltrials.gov/study/NCT06683638","title":"Daily Doxycycline for Early Syphillis","has_exemption":false,"start_date":"2025-03-03","completion_date":"2026-06-26","has_results":false,"results_due":false,"sponsor_name":"University of Washington","sponsor_slug":"university-of-washington","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06825871","publication_url":"https://clinicaltrials.gov/study/NCT06825871","title":"Automated Inhaler Monitoring for Asthma Medication Usage","has_exemption":false,"start_date":"2025-12-01","completion_date":"2026-06-26","has_results":false,"results_due":false,"sponsor_name":"Boston Children’s Hospital","sponsor_slug":"boston-childrens-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04906460","publication_url":"https://clinicaltrials.gov/study/NCT04906460","title":"An Open-label Phase 1b/2 Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy","has_exemption":false,"start_date":"2021-09-28","completion_date":"2026-06-27","has_results":false,"results_due":false,"sponsor_name":"Wave Life Sciences USA, Inc.","sponsor_slug":"wave-life-sciences-usa-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04873245","publication_url":"https://clinicaltrials.gov/study/NCT04873245","title":"Lifestyle Counseling and Medication for Adolescent Weight Management","has_exemption":false,"start_date":"2022-03-15","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"University of Minnesota","sponsor_slug":"university-of-minnesota","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06283797","publication_url":"https://clinicaltrials.gov/study/NCT06283797","title":"Assessment of the Efficacy of Automated Insulin Therapy (Artificial Pancreas) Early Initiated After Diagnosis on Blood Glucose Control in Children and Adolescents With Type 1 Diabetes: Randomized Comparison With Conventional Insulin Therapy on 1 Year, Followed by an Optional Extension on 1 Year","has_exemption":false,"start_date":"2024-05-29","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"University Hospital, Montpellier","sponsor_slug":"university-hospital-montpellier","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06402123","publication_url":"https://clinicaltrials.gov/study/NCT06402123","title":"Phase 2b Randomized, Double-blind, Placebo-controlled Crossover Study Evaluating the Efficacy and Safety of Zagociguat in Participants With MELAS (PRIZM)","has_exemption":false,"start_date":"2024-09-10","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"Tisento Therapeutics","sponsor_slug":"tisento-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06806293","publication_url":"https://clinicaltrials.gov/study/NCT06806293","title":"A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Extension to Evaluate the Efficacy, Safety, and Tolerability of Atogepant for the Preventive Treatment of Menstrual Migraine","has_exemption":false,"start_date":"2025-02-10","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"AbbVie","sponsor_slug":"abbvie","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06806657","publication_url":"https://clinicaltrials.gov/study/NCT06806657","title":"A Phase 4 Open-label Study to Evaluate the Safety After Switching to CSL312 (Garadacimab) From Current Prophylactic HAE Treatment in Subjects With HAE ≥ 12 Years of Age","has_exemption":false,"start_date":"2025-04-28","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"CSL Behring","sponsor_slug":"csl-behring","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06979154","publication_url":"https://clinicaltrials.gov/study/NCT06979154","title":"Pilot Study Using Endogenous Aperiodic Brain Activity to Personalize Transcranial Alternating Current Stimulation as a Treatment for Antenatal Depression: PandA-tACS","has_exemption":false,"start_date":"2025-08-12","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"University of North Carolina, Chapel Hill","sponsor_slug":"university-of-north-carolina-chapel-hill","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT07554417","publication_url":"https://clinicaltrials.gov/study/NCT07554417","title":"Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment","has_exemption":false,"start_date":"2026-04-06","completion_date":"2026-06-29","has_results":false,"results_due":false,"sponsor_name":"William Marsh Rice University","sponsor_slug":"william-marsh-rice-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04278521","publication_url":"https://clinicaltrials.gov/study/NCT04278521","title":"Mechanism of Action of Transcranial Magnetic Stimulation","has_exemption":false,"start_date":"2011-11-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT01606488","publication_url":"https://clinicaltrials.gov/study/NCT01606488","title":"Effects of Brain Beta Amyloid on Postoperative Cognition and 18F-AV-45-A14: Clinical Evaluation of Florbetapir F 18 (18F-AV-45)","has_exemption":false,"start_date":"2012-05-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of California, San Francisco","sponsor_slug":"university-of-california-san-francisco","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02313194","publication_url":"https://clinicaltrials.gov/study/NCT02313194","title":"Enabling Forelimb Function With Agonist Drug and Epidural Stimulation in SCI","has_exemption":false,"start_date":"2013-07-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of California, Los Angeles","sponsor_slug":"university-of-california-los-angeles","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02020070","publication_url":"https://clinicaltrials.gov/study/NCT02020070","title":"A Phase 2 Study Combining Ipilimumab, Degarelix, and Radical Prostatectomy in Men With Newly Diagnosed Metastatic Castration Sensitive Prostate Cancer or Ipilimumab and Degarelix in Men With Biochemically Recurrent Castration Sensitive Prostate Cancer After Radical Prostatectomy","has_exemption":false,"start_date":"2013-12-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Memorial Sloan Kettering Cancer Center","sponsor_slug":"memorial-sloan-kettering-cancer-center","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02446444","publication_url":"https://clinicaltrials.gov/study/NCT02446444","title":"Randomised Phase 3 Trial of Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer: ENZARAD","has_exemption":false,"start_date":"2014-03-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Sydney","sponsor_slug":"university-of-sydney","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT01954992","publication_url":"https://clinicaltrials.gov/study/NCT01954992","title":"A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared With Fluorouracil (5-FU) in Patients With Metastatic Pancreatic Adenocarcinoma Previously Treated With Gemcitabine","has_exemption":false,"start_date":"2014-04-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Eleison Pharmaceuticals LLC.","sponsor_slug":"eleison-pharmaceuticals-llc","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02112617","publication_url":"https://clinicaltrials.gov/study/NCT02112617","title":"Phase II Study of Proton Radiation Therapy for Neuroblastoma","has_exemption":false,"start_date":"2014-06-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02574728","publication_url":"https://clinicaltrials.gov/study/NCT02574728","title":"AflacST1502: A Phase II Study of Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors","has_exemption":false,"start_date":"2015-06-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Emory University","sponsor_slug":"emory-university","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02402660","publication_url":"https://clinicaltrials.gov/study/NCT02402660","title":"A Phase 2 Multicenter, Double-Masked, Randomized, Placebo-Controlled Study to Investigate the Long Term Safety, Tolerability, Pharmacokinetics and Effects of ALK-001 on the Progression of Stargardt Disease","has_exemption":false,"start_date":"2015-08-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Alkeus Pharmaceuticals, Inc.","sponsor_slug":"alkeus-pharmaceuticals-inc","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02842424","publication_url":"https://clinicaltrials.gov/study/NCT02842424","title":"Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis","has_exemption":false,"start_date":"2016-02-25","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Nebraska","sponsor_slug":"university-of-nebraska","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02650401","publication_url":"https://clinicaltrials.gov/study/NCT02650401","title":"A Phase 1/2, Open-Label, Dose-Escalation And Expansion Study Of Entrectinib (Rxdx-101) In Pediatrics With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options","has_exemption":false,"start_date":"2016-05-03","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Hoffmann-La Roche","sponsor_slug":"hoffmann-la-roche","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT03244163","publication_url":"https://clinicaltrials.gov/study/NCT03244163","title":"Randomized Controlled Trial of Spyglass DS Peroral Cholangioscope Guided Laser Lithotripsy or Electrohydraulic Lithotripsy Versus Conventional Basket Mechanical Lithotripsy for Endoscopic Removal of Complicated Bile Duct Stones","has_exemption":false,"start_date":"2016-06-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Chinese University of Hong Kong","sponsor_slug":"chinese-university-of-hong-kong","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT04691960","publication_url":"https://clinicaltrials.gov/study/NCT04691960","title":"A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging","has_exemption":false,"start_date":"2016-08-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Weill Medical College of Cornell University","sponsor_slug":"weill-medical-college-of-cornell-university","status":"ongoing","is_pact":true,"days_late":null},{"registry_id":"NCT02875353","publication_url":"https://clinicaltrials.gov/study/NCT02875353","title":"Blood Flow Monitoring to Prevent Post-Polypectomy Induced Ulcer Bleeding","has_exemption":false,"start_date":"2017-02-15","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"VA Office of Research and Development","sponsor_slug":"va-office-of-research-and-development","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03184545","publication_url":"https://clinicaltrials.gov/study/NCT03184545","title":"A Prospective Randomized Study Comparing the Outcome of Electrical Stimulation of Vastus Medialis Obliquus Muscle and Physical Therapy Vs Only Physical Therapy but No Electrical Stimulation in Patients with Patellofemoral Pain Syndrome","has_exemption":false,"start_date":"2017-07-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Northwell Health","sponsor_slug":"northwell-health","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03007147","publication_url":"https://clinicaltrials.gov/study/NCT03007147","title":"International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Testing Imatinib in Combination With Two Different Cytotoxic Chemotherapy Backbones","has_exemption":false,"start_date":"2017-08-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Children's Oncology Group","sponsor_slug":"childrens-oncology-group","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03434392","publication_url":"https://clinicaltrials.gov/study/NCT03434392","title":"QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing","has_exemption":false,"start_date":"2017-10-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Anna Evans Phillips","sponsor_slug":"anna-evans-phillips","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02922036","publication_url":"https://clinicaltrials.gov/study/NCT02922036","title":"Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in Non-Responders, Previously Untreatable and High Risk Upgrade Patients (SOLVE CRT)","has_exemption":false,"start_date":"2018-01-17","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"EBR Systems, Inc.","sponsor_slug":"ebr-systems-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03257033","publication_url":"https://clinicaltrials.gov/study/NCT03257033","title":"Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine Plus Nab-Paclitaxel Following Induction With Sequential IV Gemcitabine Plus Nab-Paclitaxel and Radiotherapy for Locally Advanced Pancreatic Cancer","has_exemption":false,"start_date":"2018-03-12","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"RenovoRx","sponsor_slug":"renovorx","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03363373","publication_url":"https://clinicaltrials.gov/study/NCT03363373","title":"A Pivotal Phase 2 Trial of Antibody Naxitamab (hu3F8) and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow","has_exemption":false,"start_date":"2018-04-03","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Y-mAbs Therapeutics","sponsor_slug":"y-mabs-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03389100","publication_url":"https://clinicaltrials.gov/study/NCT03389100","title":"Tau Positron Emission Tomography (PET) Imaging in the Northern Manhattan Study of Metabolism and Mind (NOMEM) With 18F-MK6240.","has_exemption":false,"start_date":"2018-07-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Columbia University","sponsor_slug":"columbia-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03802799","publication_url":"https://clinicaltrials.gov/study/NCT03802799","title":"An Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of ZYN002 Administered as a Transdermal Gel to Children, Adolescents, and Young Adults With Fragile X Syndrome","has_exemption":false,"start_date":"2018-11-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Zynerba Pharmaceuticals, Inc.","sponsor_slug":"zynerba-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03706833","publication_url":"https://clinicaltrials.gov/study/NCT03706833","title":"Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Mitral Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System Compared to Abbott MitraClip in Patients With Mitral Regurgitation","has_exemption":false,"start_date":"2018-11-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Edwards Lifesciences","sponsor_slug":"edwards-lifesciences","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03678883","publication_url":"https://clinicaltrials.gov/study/NCT03678883","title":"Phase 1/2 Study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK-3β) Inhibitor, as a Single Agent and Combined With Chemotherapy, in Patients With Refractory Hematologic Malignancies or Solid Tumors","has_exemption":false,"start_date":"2019-01-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Actuate Therapeutics Inc.","sponsor_slug":"actuate-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03500445","publication_url":"https://clinicaltrials.gov/study/NCT03500445","title":"Open-label, Single-arm, Phase 2 Study of Initial Treatment With Daratumumab (Darzalex), Carfilzomib (Kyprolis), Lenalidomide (Revlimid) and Low Dose Dexamethasone (DKRd) in Newly Diagnosed, Multiple Myeloma Requiring Systemic Chemotherapy","has_exemption":false,"start_date":"2019-02-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Chicago","sponsor_slug":"university-of-chicago","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03870672","publication_url":"https://clinicaltrials.gov/study/NCT03870672","title":"Contralaterally Controlled FES Combined With Brain Stimulation for Severe Upper Limb Hemiplegia","has_exemption":false,"start_date":"2019-05-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"The Cleveland Clinic","sponsor_slug":"the-cleveland-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03667326","publication_url":"https://clinicaltrials.gov/study/NCT03667326","title":"Low-Dose Aspirin in the Postpartum Period and Endothelial Function in Patients With Preeclampsia","has_exemption":false,"start_date":"2019-07-22","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Columbia University","sponsor_slug":"columbia-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03844061","publication_url":"https://clinicaltrials.gov/study/NCT03844061","title":"A Randomized, Double-Blind, Placebo-Controlled Study of Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis","has_exemption":false,"start_date":"2019-07-29","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Hospital for Special Surgery, New York","sponsor_slug":"hospital-for-special-surgery-new-york","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04131829","publication_url":"https://clinicaltrials.gov/study/NCT04131829","title":"Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD","has_exemption":false,"start_date":"2019-10-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Yale University","sponsor_slug":"yale-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04150497","publication_url":"https://clinicaltrials.gov/study/NCT04150497","title":"Open Label Dose-escalation and Dose-expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCART22 (Allogeneic Engineered T-cells Expressing Anti-CD22 Chimeric Antigen Receptor) in Patients With Relapsed or refractoryCD22+ B-cell Acute Lymphoblastic Leukemia (B-ALL)","has_exemption":false,"start_date":"2019-10-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cellectis S.A.","sponsor_slug":"cellectis-sa","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04130516","publication_url":"https://clinicaltrials.gov/study/NCT04130516","title":"A Multicenter Phase 1-2A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of LNS8801 in Patients With Advanced Cancer With and Without Pembrolizumab","has_exemption":false,"start_date":"2019-10-21","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Linnaeus Therapeutics, Inc.","sponsor_slug":"linnaeus-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04014205","publication_url":"https://clinicaltrials.gov/study/NCT04014205","title":"A Phase I/II，Multicenter, Open-Label, Study of a Novel Bruton's Tyrosine Kinase Inhibitor, Orelabrutinib, in Patients With B-Cell Malignancies","has_exemption":false,"start_date":"2019-11-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Beijing InnoCare Pharma Tech Co., Ltd.","sponsor_slug":"beijing-innocare-pharma-tech-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04023552","publication_url":"https://clinicaltrials.gov/study/NCT04023552","title":"A Randomized Double-blind, Placebo-controlled, Multicenter Trial Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With Established Cardiovascular Disease","has_exemption":false,"start_date":"2019-12-12","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Novartis Pharmaceuticals","sponsor_slug":"novartis-pharmaceuticals","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04218968","publication_url":"https://clinicaltrials.gov/study/NCT04218968","title":"The Effect of Adrenergic Blocker Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease: A Follow up Study","has_exemption":false,"start_date":"2019-12-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cedars-Sinai Medical Center","sponsor_slug":"cedars-sinai-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04261712","publication_url":"https://clinicaltrials.gov/study/NCT04261712","title":"An Open Label, Long-term Extension Study to Evaluate the Safety and Efficacy of CRN00808 in Subjects With Acromegaly (ACROBAT Advance)","has_exemption":false,"start_date":"2020-01-29","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Crinetics Pharmaceuticals Inc.","sponsor_slug":"crinetics-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03911505","publication_url":"https://clinicaltrials.gov/study/NCT03911505","title":"An Open-label Study of the Safety, Pharmacokinetics, Efficacy, Pharmacodynamics, and Immunogenicity of Cipaglucosidase Alfa/Miglustat in Pediatric Subjects Aged 0 to < 18 Years With Late-onset Pompe Disease","has_exemption":false,"start_date":"2020-02-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Amicus Therapeutics","sponsor_slug":"amicus-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03838445","publication_url":"https://clinicaltrials.gov/study/NCT03838445","title":"RELIEVE-PAH TRIAL: REducing Right ventricuLar faIlure With thE V-waVe Shunt in Pulmonary Arterial Hypertension","has_exemption":false,"start_date":"2020-02-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"V-Wave Ltd","sponsor_slug":"v-wave-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03838042","publication_url":"https://clinicaltrials.gov/study/NCT03838042","title":"INFORM2 Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies (INFORM2-NivEnt)","has_exemption":false,"start_date":"2020-05-26","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University Hospital Heidelberg","sponsor_slug":"university-hospital-heidelberg","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04517149","publication_url":"https://clinicaltrials.gov/study/NCT04517149","title":"An Open-label, Phase 1/2 Trial of Gene Therapy 4D-125 in Males With X-linked Retinitis Pigmentosa (XLRP) Caused by Mutations in the RPGR Gene","has_exemption":false,"start_date":"2020-06-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"4D Molecular Therapeutics","sponsor_slug":"4d-molecular-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04438824","publication_url":"https://clinicaltrials.gov/study/NCT04438824","title":"A Phase II Study of CDK4/6 Inhibition (Palbociclib) Combined With PD-1 Blockade (INCMGA00012) in Patients With Advanced Well-differentiated Dedifferentiated Liposarcoma","has_exemption":false,"start_date":"2020-06-17","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Memorial Sloan Kettering Cancer Center","sponsor_slug":"memorial-sloan-kettering-cancer-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04000659","publication_url":"https://clinicaltrials.gov/study/NCT04000659","title":"A Prospective, Randomized, Controlled, Multi-Center Study to Evaluate the Safety and Effectiveness of the Episealer® Knee System Compared to Microfracture for the Treatment of Focal Femoral Knee Chondral or Osteochondral Lesions","has_exemption":false,"start_date":"2020-06-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Episurf Medical Inc.","sponsor_slug":"episurf-medical-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04442724","publication_url":"https://clinicaltrials.gov/study/NCT04442724","title":"Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy","has_exemption":false,"start_date":"2020-07-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cedars-Sinai Medical Center","sponsor_slug":"cedars-sinai-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04520178","publication_url":"https://clinicaltrials.gov/study/NCT04520178","title":"Effects of the Serotonin Precursor, 5-hydroxytryptophan, in the Injured Human Spinal Cord","has_exemption":false,"start_date":"2020-07-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Alberta","sponsor_slug":"university-of-alberta","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04357821","publication_url":"https://clinicaltrials.gov/study/NCT04357821","title":"Combinatorial Therapy With a Therapeutic Conserved Element DNA Vaccine, MVA Vaccine Boost, TLR9 Agonist and Broadly Neutralizing Antibodies: a Proof-of-concept Study Aimed at Inducing an HIV Remission","has_exemption":false,"start_date":"2020-08-01","completion_date":"2026-06-30","has_results":true,"results_due":false,"sponsor_name":"University of California, San Francisco","sponsor_slug":"university-of-california-san-francisco","status":"reported","is_pact":false,"days_late":null},{"registry_id":"NCT04554212","publication_url":"https://clinicaltrials.gov/study/NCT04554212","title":"Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)","has_exemption":false,"start_date":"2020-09-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Caitlin Conley","sponsor_slug":"caitlin-conley","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04140526","publication_url":"https://clinicaltrials.gov/study/NCT04140526","title":"Safety, Pharmacokinetics (PK), and Efficacy of ONC-392 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumors and NSCLC: An Open Label Phase IA/IB Study. Preserve CTLA4 Checkpoint Function (PRESERVE-001)","has_exemption":false,"start_date":"2020-09-16","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"OncoC4, Inc.","sponsor_slug":"oncoc4-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT03754725","publication_url":"https://clinicaltrials.gov/study/NCT03754725","title":"A Phase 1/2a Exploratory Clinical Trial to Evaluate the Safety of Oral Deferiprone (14 Days) Including Its Effect on Decreasing the Content of Iron in Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) sIRB","has_exemption":false,"start_date":"2020-10-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Duke University","sponsor_slug":"duke-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04389749","publication_url":"https://clinicaltrials.gov/study/NCT04389749","title":"The Role of Continuous Passive Motion in Pain Control of Patients Undergoing Operative Management of Isolated Acetabular Fractures, Supracondylar Femur Fractures, or Tibial Plateau Fracture: A Comparative Study","has_exemption":false,"start_date":"2020-10-06","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Cincinnati","sponsor_slug":"university-of-cincinnati","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04620551","publication_url":"https://clinicaltrials.gov/study/NCT04620551","title":"Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease: An Investigation of STN LFP Biomarkers in Sleep Dysregulation and Repair","has_exemption":false,"start_date":"2020-10-21","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Nebraska","sponsor_slug":"university-of-nebraska","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04500899","publication_url":"https://clinicaltrials.gov/study/NCT04500899","title":"Evaluating the Severity of Mitral Regurgitation Using Phenylephrine During Transesophageal Echocardiography","has_exemption":false,"start_date":"2020-12-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Montefiore Medical Center","sponsor_slug":"montefiore-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04722263","publication_url":"https://clinicaltrials.gov/study/NCT04722263","title":"Primary Radiotherapy for the Treatment of Keloids: A Pilot Study","has_exemption":false,"start_date":"2020-12-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Montefiore Medical Center","sponsor_slug":"montefiore-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04663308","publication_url":"https://clinicaltrials.gov/study/NCT04663308","title":"A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients With Primary Sclerosing Cholangitis","has_exemption":false,"start_date":"2020-12-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mirum Pharmaceuticals, Inc.","sponsor_slug":"mirum-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04305795","publication_url":"https://clinicaltrials.gov/study/NCT04305795","title":"An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors","has_exemption":false,"start_date":"2020-12-21","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Rakuten Medical, Inc.","sponsor_slug":"rakuten-medical-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT02347111","publication_url":"https://clinicaltrials.gov/study/NCT02347111","title":"A Prospective, Multi-Center, Randomized, Open Label Trial to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs","has_exemption":false,"start_date":"2020-12-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Illinois at Chicago","sponsor_slug":"university-of-illinois-at-chicago","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04842890","publication_url":"https://clinicaltrials.gov/study/NCT04842890","title":"Phase II Study of Pencil Beam Scanning Proton Stereotactic Body Radiation Therapy for Prostate Cancer","has_exemption":false,"start_date":"2021-01-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"The New York Proton Center","sponsor_slug":"the-new-york-proton-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04655092","publication_url":"https://clinicaltrials.gov/study/NCT04655092","title":"Extension Study of P1101 in Japanese Patients Who Have Completed Phase 2 Single Arm Study in Polycythemia Vera (PV) Patients (Study A19-201) or Phase 3 Study in Essential Thrombocythemia (ET) Patients (Study P1101 ET)","has_exemption":false,"start_date":"2021-01-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"PharmaEssentia Japan K.K.","sponsor_slug":"pharmaessentia-japan-kk","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04160910","publication_url":"https://clinicaltrials.gov/study/NCT04160910","title":"5HTP Regulation Of Asthma In Children","has_exemption":false,"start_date":"2021-02-11","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Indiana University","sponsor_slug":"indiana-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04901975","publication_url":"https://clinicaltrials.gov/study/NCT04901975","title":"Acute Imposition of Fontan Physiology in The Single Ventricle Patient: Effects on Fibrosis, Function and Drug Intervention","has_exemption":false,"start_date":"2021-02-11","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Children's Hospital of Philadelphia","sponsor_slug":"childrens-hospital-of-philadelphia","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04506008","publication_url":"https://clinicaltrials.gov/study/NCT04506008","title":"Prospective Observational Trial of Two Neoadjuvant Hypofractionated Radiotherapy Regimens Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas","has_exemption":false,"start_date":"2021-03-02","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Vanderbilt-Ingram Cancer Center","sponsor_slug":"vanderbilt-ingram-cancer-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04623099","publication_url":"https://clinicaltrials.gov/study/NCT04623099","title":"Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)","has_exemption":false,"start_date":"2021-03-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Cincinnati","sponsor_slug":"university-of-cincinnati","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04544592","publication_url":"https://clinicaltrials.gov/study/NCT04544592","title":"Phase I/II Dose Escalation and Preliminary Efficacy of CD19 Directed CAR-T Cells Generated Using the Miltenyi CliniMACs Prodigy System (UCD19 CAR-T) in Pediatric Patients With Relapsed and/or Refractory B-Cell Acute Lymphoblastic Leukemia (B-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL)","has_exemption":false,"start_date":"2021-03-10","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Colorado, Denver","sponsor_slug":"university-of-colorado-denver","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04858269","publication_url":"https://clinicaltrials.gov/study/NCT04858269","title":"Phase II Study of First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients","has_exemption":false,"start_date":"2021-05-27","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Wake Forest University Health Sciences","sponsor_slug":"wake-forest-university-health-sciences","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04922736","publication_url":"https://clinicaltrials.gov/study/NCT04922736","title":"Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases","has_exemption":false,"start_date":"2021-06-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Utah","sponsor_slug":"university-of-utah","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04451044","publication_url":"https://clinicaltrials.gov/study/NCT04451044","title":"Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting","has_exemption":false,"start_date":"2021-06-17","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Philips Clinical & Medical Affairs Global","sponsor_slug":"philips-clinical-medical-affairs-global","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04925024","publication_url":"https://clinicaltrials.gov/study/NCT04925024","title":"Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS) : A Phase IIb Clinical Trial.","has_exemption":false,"start_date":"2021-06-25","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Longeveron Inc.","sponsor_slug":"longeveron-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04793685","publication_url":"https://clinicaltrials.gov/study/NCT04793685","title":"Prazosin Treatment for Alcohol Use Disorder With Alcohol Withdrawal Symptoms","has_exemption":false,"start_date":"2021-07-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Yale University","sponsor_slug":"yale-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04926467","publication_url":"https://clinicaltrials.gov/study/NCT04926467","title":"An Open Label, Phase II Study of Chemotherapy + Anakinra in Patients With Resectable, Locally Advanced or Potentially Resectable Pancreatic Adenocarcinoma (PDAC)","has_exemption":false,"start_date":"2021-07-23","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Baylor Research Institute","sponsor_slug":"baylor-research-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04986683","publication_url":"https://clinicaltrials.gov/study/NCT04986683","title":"Novel DWI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery","has_exemption":false,"start_date":"2021-08-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Wayne State University","sponsor_slug":"wayne-state-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04386005","publication_url":"https://clinicaltrials.gov/study/NCT04386005","title":"Continuous Glucose Monitoring in At-Risk Newborns: A Feasibility Study","has_exemption":false,"start_date":"2021-08-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Milton S. Hershey Medical Center","sponsor_slug":"milton-s-hershey-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05086692","publication_url":"https://clinicaltrials.gov/study/NCT05086692","title":"A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors","has_exemption":false,"start_date":"2021-08-27","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Medicenna Therapeutics, Inc.","sponsor_slug":"medicenna-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04994132","publication_url":"https://clinicaltrials.gov/study/NCT04994132","title":"A Randomized Phase 3 Trial of Vinorelbine, Dactinomycin, and Cyclophosphamide (VINO-AC) Plus Maintenance Chemotherapy With Vinorelbine and Oral Cyclophosphamide (VINO-CPO) vs Vincristine, Dactinomycin and Cyclophosphamide (VAC) Plus VINO-CPO Maintenance in Patients With High Risk Rhabdomyosarcoma (HR-RMS)","has_exemption":false,"start_date":"2021-09-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Children's Oncology Group","sponsor_slug":"childrens-oncology-group","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04955366","publication_url":"https://clinicaltrials.gov/study/NCT04955366","title":"Late Abatacept Conversion in Kidney Transplant Recipients Receiving Belatacept: a Prospective, Randomized Controlled Non-inferiority Trial. IM101-884","has_exemption":false,"start_date":"2021-09-22","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Emory University","sponsor_slug":"emory-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05968885","publication_url":"https://clinicaltrials.gov/study/NCT05968885","title":"Evaluation of the Efficacy and Urodynamic Outcomes Between Intradetrusor onabotulinumtoxinA Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity","has_exemption":false,"start_date":"2021-10-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mackay Memorial Hospital","sponsor_slug":"mackay-memorial-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05104983","publication_url":"https://clinicaltrials.gov/study/NCT05104983","title":"Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study","has_exemption":false,"start_date":"2021-10-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Darcy Krueger","sponsor_slug":"darcy-krueger","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05299658","publication_url":"https://clinicaltrials.gov/study/NCT05299658","title":"An Open-Label Extension for the Phase 2, Randomised, Double-Blind, Placebo-Controlled Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS","has_exemption":false,"start_date":"2021-11-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Clene Nanomedicine","sponsor_slug":"clene-nanomedicine","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05070013","publication_url":"https://clinicaltrials.gov/study/NCT05070013","title":"Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease: An Investigation of STN LFP Biomarkers in Sleep Dysregulation and Repair","has_exemption":false,"start_date":"2021-11-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Nebraska","sponsor_slug":"university-of-nebraska","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05204862","publication_url":"https://clinicaltrials.gov/study/NCT05204862","title":"A Phase 1/2 Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TU2218, an Oral TGFβR Inhibitor, Administered Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors","has_exemption":false,"start_date":"2021-12-02","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"TiumBio Co., Ltd.","sponsor_slug":"tiumbio-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05023486","publication_url":"https://clinicaltrials.gov/study/NCT05023486","title":"NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies","has_exemption":false,"start_date":"2021-12-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Novita Pharmaceuticals, Inc.","sponsor_slug":"novita-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04996628","publication_url":"https://clinicaltrials.gov/study/NCT04996628","title":"Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis","has_exemption":false,"start_date":"2022-01-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Pittsburgh","sponsor_slug":"university-of-pittsburgh","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05085210","publication_url":"https://clinicaltrials.gov/study/NCT05085210","title":"Visual Restoration of Losses Caused by Cortical Damage: a New Protocol to Promote Fast Recovery","has_exemption":false,"start_date":"2022-01-25","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Beth Israel Deaconess Medical Center","sponsor_slug":"beth-israel-deaconess-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05304351","publication_url":"https://clinicaltrials.gov/study/NCT05304351","title":"A Randomized, Observer-Blind, Phase 2 Study To Assess the Safety and Immunogenicity of CRV-101 Vaccine Head-To-Head With SHINGRIX® for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older","has_exemption":false,"start_date":"2022-02-02","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Curevo Inc","sponsor_slug":"curevo-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05034536","publication_url":"https://clinicaltrials.gov/study/NCT05034536","title":"A Phase II Study of PD-1 Blockade With or Without LAG-3 Inhibition in Combination With Infliximab for the Treatment of Metastatic Melanoma and Prevention of Adverse Events","has_exemption":false,"start_date":"2022-02-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Massachusetts General Hospital","sponsor_slug":"massachusetts-general-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05280366","publication_url":"https://clinicaltrials.gov/study/NCT05280366","title":"A Prospective, Randomized, Multi-center Evaluation of the Safety and Effectiveness of the STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma","has_exemption":false,"start_date":"2022-02-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"New World Medical, Inc.","sponsor_slug":"new-world-medical-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05166161","publication_url":"https://clinicaltrials.gov/study/NCT05166161","title":"A Phase 3 Open-Label Study of PTC923 (Sepiapterin) in Phenylketonuria","has_exemption":false,"start_date":"2022-02-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"PTC Therapeutics","sponsor_slug":"ptc-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05183204","publication_url":"https://clinicaltrials.gov/study/NCT05183204","title":"A Phase 2 Trial of Paxalisib Combined With a Ketogenic Diet and Metformin for Newly Diagnosed and Recurrent Glioblastoma","has_exemption":false,"start_date":"2022-02-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Weill Medical College of Cornell University","sponsor_slug":"weill-medical-college-of-cornell-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05383274","publication_url":"https://clinicaltrials.gov/study/NCT05383274","title":"Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters","has_exemption":false,"start_date":"2022-02-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Urotronic Inc.","sponsor_slug":"urotronic-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05231460","publication_url":"https://clinicaltrials.gov/study/NCT05231460","title":"Do Experience of Pain and 30-Day Surgery Outcomes Differ in Robotic Bariatric Surgery Patients Treated With Narcotic vs. Non-narcotic Pain Management Protocols?","has_exemption":false,"start_date":"2022-02-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Arizona","sponsor_slug":"university-of-arizona","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04502758","publication_url":"https://clinicaltrials.gov/study/NCT04502758","title":"A Randomized Controlled Trial of Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation Associated With Major Depressive Disorder","has_exemption":false,"start_date":"2022-04-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mayo Clinic","sponsor_slug":"mayo-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05316181","publication_url":"https://clinicaltrials.gov/study/NCT05316181","title":"Randomized Phase III Trial of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Platinum-Resistant Recurrent Ovarian Cancer: KOV-02R - Resistant Cancer of Ovary (RECOVER)","has_exemption":false,"start_date":"2022-04-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"National Cancer Center, Korea","sponsor_slug":"national-cancer-center-korea","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05074810","publication_url":"https://clinicaltrials.gov/study/NCT05074810","title":"A Phase 1/2 Study of Avutometinib (VS-6766) in Combination With Sotorasib With or Without Defactinib in Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC)","has_exemption":false,"start_date":"2022-04-12","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Verastem, Inc.","sponsor_slug":"verastem-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05418244","publication_url":"https://clinicaltrials.gov/study/NCT05418244","title":"Inhaled Isopropyl Alcohol for the Treatment of Nausea in a Pediatric Emergency Department: A Open Label, Randomized Controlled Clinical Trial","has_exemption":false,"start_date":"2022-04-20","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"State University of New York at Buffalo","sponsor_slug":"state-university-of-new-york-at-buffalo","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04380038","publication_url":"https://clinicaltrials.gov/study/NCT04380038","title":"Viral Infection in Asthma (VIA) Study","has_exemption":false,"start_date":"2022-05-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Virginia","sponsor_slug":"university-of-virginia","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05369052","publication_url":"https://clinicaltrials.gov/study/NCT05369052","title":"A Phase 3, Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)","has_exemption":false,"start_date":"2022-05-03","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"MicuRx","sponsor_slug":"micurx","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04939597","publication_url":"https://clinicaltrials.gov/study/NCT04939597","title":"A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors","has_exemption":false,"start_date":"2022-05-10","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Children's Oncology Group","sponsor_slug":"childrens-oncology-group","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05353257","publication_url":"https://clinicaltrials.gov/study/NCT05353257","title":"A Randomized, Double-Blind, International Multicenter, Phase III Study to Evaluate the Anti-Tumor Efficacy and Safety of Serplulimab or Placebo in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer","has_exemption":false,"start_date":"2022-05-17","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Shanghai Henlius Biotech","sponsor_slug":"shanghai-henlius-biotech","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05424354","publication_url":"https://clinicaltrials.gov/study/NCT05424354","title":"Prospective Randomized Open Label Multicenter Phase IV Clinical Trial to Compare Transforming Powder Dressing (TPD) to Current Standard of Care (SOC) Dressing Therapies in Acute Partial Thickness Burn Wounds","has_exemption":false,"start_date":"2022-05-26","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"ULURU Inc.","sponsor_slug":"uluru-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05168163","publication_url":"https://clinicaltrials.gov/study/NCT05168163","title":"A Phase II Randomized Study of Atezolizumab Plus Multi-Kinase Inhibitor Versus Multi-Kinase Inhibitor Alone in Subjects With Unresectable, Advanced Hepatocellular Carcinoma Who Previously Received Atezolizumab Plus Bevacizumab","has_exemption":false,"start_date":"2022-05-27","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Academic and Community Cancer Research United","sponsor_slug":"academic-and-community-cancer-research-united","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06197295","publication_url":"https://clinicaltrials.gov/study/NCT06197295","title":"Efficacy and Safety of Solifenacin Combined With Mirabegron Versus Solifenacin With Vaginal Estrogen Cream for the Treatment of Detrusor Overactivity","has_exemption":false,"start_date":"2022-06-16","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mackay Memorial Hospital","sponsor_slug":"mackay-memorial-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06479720","publication_url":"https://clinicaltrials.gov/study/NCT06479720","title":"Efficacy and Safety of Solifenacin or Mirabegron With Local Estrogen Versus Combination Treatment With Mirabegron and Solifenacin for Refractory Overactive Bladder","has_exemption":false,"start_date":"2022-06-16","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mackay Memorial Hospital","sponsor_slug":"mackay-memorial-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05171335","publication_url":"https://clinicaltrials.gov/study/NCT05171335","title":"Neoadjuvant Combination Therapy of Lenvima Plus Transcatheter Arterial Chemoembolization (TACE) for Transplant-Eligible Patients With Large Hepatocellular Carcinoma","has_exemption":false,"start_date":"2022-06-20","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"The Methodist Hospital Research Institute","sponsor_slug":"the-methodist-hospital-research-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05350332","publication_url":"https://clinicaltrials.gov/study/NCT05350332","title":"Characterizing the Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea","has_exemption":false,"start_date":"2022-06-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Emory University","sponsor_slug":"emory-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04565795","publication_url":"https://clinicaltrials.gov/study/NCT04565795","title":"URIPRENE: Clinical Study to Evaluate the Safety and Device Performance of the ADVA-Tec Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy","has_exemption":false,"start_date":"2022-07-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Adva-Tec","sponsor_slug":"adva-tec","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05488340","publication_url":"https://clinicaltrials.gov/study/NCT05488340","title":"A Phase 2, Double-blind, Randomized, Active-controlled Evaluation of the Safety, Tolerability, Pharmacokinetics and Efficacy of LBP-EC01 in the Treatment of Acute Uncomplicated Urinary Tract Infection Caused by Drug Resistant E. Coli","has_exemption":false,"start_date":"2022-07-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Locus Biosciences","sponsor_slug":"locus-biosciences","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05391971","publication_url":"https://clinicaltrials.gov/study/NCT05391971","title":"A Randomized, Double Blind, Placebo-controlled Study of the Effects of Stellate Ganglion Block on Neural Activity and Symptoms in Participants With Post-traumatic Stress Disorder","has_exemption":false,"start_date":"2022-08-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"NYU Langone Health","sponsor_slug":"nyu-langone-health","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05249101","publication_url":"https://clinicaltrials.gov/study/NCT05249101","title":"A Phase 1b/2, Dose-escalation, Randomized, Multicenter Study of Maintenance Ivaltinostat Plus Capecitabine or Capecitabine in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on FOLFIRINOX","has_exemption":false,"start_date":"2022-08-15","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"CG Pharmaceuticals, Inc","sponsor_slug":"cg-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05094570","publication_url":"https://clinicaltrials.gov/study/NCT05094570","title":"Interleukin-4Ralpha Blockade by Dupilumab Decreases Staphylococcus Aureus Colonization and Increases Microbial Diversity in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)","has_exemption":false,"start_date":"2022-09-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Virginia","sponsor_slug":"university-of-virginia","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05292404","publication_url":"https://clinicaltrials.gov/study/NCT05292404","title":"Impact of Early PCSK9 Inhibitor Treatment on Heart After Acute Myocardium Infarction： a Muti-center, Open-label, Randomized Controlled Trial","has_exemption":false,"start_date":"2022-10-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Shanghai Tong Ren Hospital","sponsor_slug":"shanghai-tong-ren-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05530343","publication_url":"https://clinicaltrials.gov/study/NCT05530343","title":"A Multicenter Randomized Trial of Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance (The SWAT-BE Study)","has_exemption":false,"start_date":"2022-10-03","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Colorado, Denver","sponsor_slug":"university-of-colorado-denver","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04909138","publication_url":"https://clinicaltrials.gov/study/NCT04909138","title":"Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy","has_exemption":false,"start_date":"2022-10-15","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Rush University Medical Center","sponsor_slug":"rush-university-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05629559","publication_url":"https://clinicaltrials.gov/study/NCT05629559","title":"An Open-Label, Phase 1/2a Trial of Gene Therapy 4D-310 in Adults With Fabry Disease and Cardiac Involvement","has_exemption":false,"start_date":"2022-10-16","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"4D Molecular Therapeutics","sponsor_slug":"4d-molecular-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04650932","publication_url":"https://clinicaltrials.gov/study/NCT04650932","title":"Dual Frequency, Dual Region Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease","has_exemption":false,"start_date":"2022-10-22","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of California, Davis","sponsor_slug":"university-of-california-davis","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05585320","publication_url":"https://clinicaltrials.gov/study/NCT05585320","title":"A Phase 1/2a, Open-Label, Multicenter, Nonrandomized, Safety and Anti-tumor Activity Study of IMM-1-104, a Novel Oral Dual MEK1/2 Inhibitor in Participants With Advanced or Metastatic Solid Tumors","has_exemption":false,"start_date":"2022-10-31","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Immuneering Corporation","sponsor_slug":"immuneering-corporation","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05404581","publication_url":"https://clinicaltrials.gov/study/NCT05404581","title":"A Staged, Comprehensive Investigation of Insular Neuromodulation for Treatment-refractory, Chronic Neuropathic Pain","has_exemption":false,"start_date":"2022-11-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Virginia","sponsor_slug":"university-of-virginia","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05556720","publication_url":"https://clinicaltrials.gov/study/NCT05556720","title":"Bringing Optimised COVID-19 Vaccine Schedules To ImmunoCompromised Populations (BOOST-IC): an Adaptive Randomised Controlled Clinical Trial","has_exemption":false,"start_date":"2022-12-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Monash University","sponsor_slug":"monash-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05501886","publication_url":"https://clinicaltrials.gov/study/NCT05501886","title":"Phase 3, Open-Label, Randomized, Study Comparing Gedatolisib Combined With Fulvestrant & With or Without Palbociclib to Standard-of-Care Therapies in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer Previously Treated With a CDK4/6 Inhibitor in Combination w/Non-Steroidal Aromatase Inhibitor Therapy","has_exemption":false,"start_date":"2022-12-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Celcuity, Inc.","sponsor_slug":"celcuity-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05637801","publication_url":"https://clinicaltrials.gov/study/NCT05637801","title":"A Randomized, Double-blind, Sham-controlled Pivotal Study of Sensory Stimulation in Subjects With Alzheimer's Disease (HOPE Study)","has_exemption":false,"start_date":"2022-12-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cognito Therapeutics, Inc.","sponsor_slug":"cognito-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05731271","publication_url":"https://clinicaltrials.gov/study/NCT05731271","title":"A First-in-Human, Open-Label, Multi-Center Phase 1 Study of TST003 in Subjects With Locally Advanced or Metastatic Solid Tumors","has_exemption":false,"start_date":"2023-02-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Suzhou Transcenta Therapeutics Co., Ltd.","sponsor_slug":"suzhou-transcenta-therapeutics-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05558605","publication_url":"https://clinicaltrials.gov/study/NCT05558605","title":"Use of Artificial Intelligence-Guided Echocardiography to assIst cardiovascuLar Patient managEment","has_exemption":false,"start_date":"2023-02-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Baker Heart and Diabetes Institute","sponsor_slug":"baker-heart-and-diabetes-institute","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05824832","publication_url":"https://clinicaltrials.gov/study/NCT05824832","title":"Effects of a Triple Adjuvant Combination of Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery, a Prospective, Randomized Clinical Trial","has_exemption":false,"start_date":"2023-02-28","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Loyola University","sponsor_slug":"loyola-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05604222","publication_url":"https://clinicaltrials.gov/study/NCT05604222","title":"Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Women","has_exemption":false,"start_date":"2023-03-05","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Shachi Tyagi","sponsor_slug":"shachi-tyagi","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05733221","publication_url":"https://clinicaltrials.gov/study/NCT05733221","title":"Determining the Ease of Utilizing 3D Printed Models to Aide in Isolated Mandibular Fracture Repair","has_exemption":false,"start_date":"2023-03-11","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Cincinnati","sponsor_slug":"university-of-cincinnati","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05457556","publication_url":"https://clinicaltrials.gov/study/NCT05457556","title":"A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) Versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) With Acute Leukemia or Myelodysplastic Syndrome (MDS)","has_exemption":false,"start_date":"2023-03-15","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Children's Oncology Group","sponsor_slug":"childrens-oncology-group","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05835999","publication_url":"https://clinicaltrials.gov/study/NCT05835999","title":"Clinical Evaluation of mTORC1 Inhibition for Geroprotection","has_exemption":false,"start_date":"2023-03-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Wisconsin, Madison","sponsor_slug":"university-of-wisconsin-madison","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05816252","publication_url":"https://clinicaltrials.gov/study/NCT05816252","title":"A Phase II Study of SKB264 as Monotherapy or as Combination Therapy in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer","has_exemption":false,"start_date":"2023-04-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Klus Pharma Inc.","sponsor_slug":"klus-pharma-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05424198","publication_url":"https://clinicaltrials.gov/study/NCT05424198","title":"The Effectiveness and Procedural Characteristics of the Trident Multi-tined Cannula for Cervical Medial Branch Radiofrequency Ablation Compared to the Conventional Cannula; A Multi-site, Single Blinded, Randomized Controlled Trial","has_exemption":false,"start_date":"2023-04-26","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Utah","sponsor_slug":"university-of-utah","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05378555","publication_url":"https://clinicaltrials.gov/study/NCT05378555","title":"A Pilot Study of the Use of Oral Ketamine for Treatment of Vaso-Occlusive Pain in Adolescents and Young Adults","has_exemption":false,"start_date":"2023-05-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Boston Children’s Hospital","sponsor_slug":"boston-childrens-hospital","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05737121","publication_url":"https://clinicaltrials.gov/study/NCT05737121","title":"A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multi-Center Single Dose Study to Evaluate the Safety and Effectiveness of VNX001 Compared to Placebo, and the Individual Components of Lidocaine, and Heparin in Subjects With Interstitial Cystitis/Bladder Pain Syndrome Who Have an Episode of Acute Bladder Pain of Moderate to Severe Intensity; The Engage 2024 Study","has_exemption":false,"start_date":"2023-05-22","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Vaneltix Pharma, Inc.","sponsor_slug":"vaneltix-pharma-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05870917","publication_url":"https://clinicaltrials.gov/study/NCT05870917","title":"A Prospective, Single-center, Phase II Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Newly Diagosed Primary Plasma Cell Leukemia","has_exemption":false,"start_date":"2023-05-23","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Institute of Hematology & Blood Diseases Hospital, China","sponsor_slug":"institute-of-hematology-blood-diseases-hospital-china","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05608837","publication_url":"https://clinicaltrials.gov/study/NCT05608837","title":"Efficacy and Safety of Dexamethasone ophthaLmic Suspension Eye drOps in Uveitic and Post Surgical mAculaR eDema (The LEOPARD Study)","has_exemption":false,"start_date":"2023-05-26","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Quan Dong Nguyen","sponsor_slug":"quan-dong-nguyen","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05876715","publication_url":"https://clinicaltrials.gov/study/NCT05876715","title":"LINNOVATE: A Phase 1/2 Study of Safety/Efficacy Using LURBINECTEDIN, Combined With IPILIMUMAB, and NIVOLUMAB for Advanced Soft Tissue Sarcomas","has_exemption":false,"start_date":"2023-06-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"ERLINDA M GORDON","sponsor_slug":"erlinda-m-gordon","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05763407","publication_url":"https://clinicaltrials.gov/study/NCT05763407","title":"Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII)","has_exemption":false,"start_date":"2023-06-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Foundry Innovation & Research 1, Limited (FIRE1)","sponsor_slug":"foundry-innovation-research-1-limited-fire1","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05691283","publication_url":"https://clinicaltrials.gov/study/NCT05691283","title":"Right Lateralized Posterior Cerebellar tDCS in Children With Autism Spectrum Disorder","has_exemption":false,"start_date":"2023-06-20","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Texas Southwestern Medical Center","sponsor_slug":"university-of-texas-southwestern-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05624528","publication_url":"https://clinicaltrials.gov/study/NCT05624528","title":"A Double-Blind, Randomized, Placebo-Controlled Study of Tolcapone for OCD","has_exemption":false,"start_date":"2023-06-22","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Chicago","sponsor_slug":"university-of-chicago","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05806996","publication_url":"https://clinicaltrials.gov/study/NCT05806996","title":"Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures","has_exemption":false,"start_date":"2023-06-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Mayo Clinic","sponsor_slug":"mayo-clinic","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05608668","publication_url":"https://clinicaltrials.gov/study/NCT05608668","title":"Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma","has_exemption":false,"start_date":"2023-07-27","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Duke University","sponsor_slug":"duke-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05116384","publication_url":"https://clinicaltrials.gov/study/NCT05116384","title":"A Trial to Evaluate Renal Artery Denervation in Addition to Catheter Ablation to Eliminate Atrial Fibrillation","has_exemption":false,"start_date":"2023-07-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Rochester","sponsor_slug":"university-of-rochester","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05698147","publication_url":"https://clinicaltrials.gov/study/NCT05698147","title":"Selinexor in Combination With Methotrexate and Rituximab for Relapsed /Refractory Central Nervous System (CNS) Lymphoma","has_exemption":false,"start_date":"2023-08-03","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Tong Chen, MD","sponsor_slug":"tong-chen-md","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05964829","publication_url":"https://clinicaltrials.gov/study/NCT05964829","title":"A Crossover Study Evaluating the Impact of the Cionic Neural Sleeve on Mobility, Disability, Fall Risk, and Physical Activity in Multiple Sclerosis","has_exemption":false,"start_date":"2023-09-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cionic, Inc.","sponsor_slug":"cionic-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06018428","publication_url":"https://clinicaltrials.gov/study/NCT06018428","title":"A Phase 2a, Randomized, Double-blind, Placebo-Controlled, Proof-of-Concept Trial With Part B and Open-label Extension of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)","has_exemption":false,"start_date":"2023-09-12","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Q32 Bio Inc.","sponsor_slug":"q32-bio-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05786573","publication_url":"https://clinicaltrials.gov/study/NCT05786573","title":"A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With An Open Label Safety and Dose Confirmation Run-In Period, To Evaluate the Efficacy and Safety of Obexelimab in Patients With Warm Autoimmune Hemolytic Anemia (SApHiAre)","has_exemption":false,"start_date":"2023-09-25","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Zenas BioPharma (USA), LLC","sponsor_slug":"zenas-biopharma-usa-llc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05895747","publication_url":"https://clinicaltrials.gov/study/NCT05895747","title":"31P-MRS and Resting State Functional Connectivity Analysis of the Effects of 5-hydroxytryptophan and Creatine for Antidepressant Augmentation in Patients With SSRI/SNRI-resistant Major Depressive Disorder","has_exemption":false,"start_date":"2023-09-28","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Utah","sponsor_slug":"university-of-utah","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05933603","publication_url":"https://clinicaltrials.gov/study/NCT05933603","title":"Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome","has_exemption":false,"start_date":"2023-09-29","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Arizona","sponsor_slug":"university-of-arizona","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06048315","publication_url":"https://clinicaltrials.gov/study/NCT06048315","title":"A Single Center, Single Arm Clinical Study on the Treatment of Advanced Non-small Cell","has_exemption":false,"start_date":"2023-09-30","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Degan Lu","sponsor_slug":"degan-lu","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06038578","publication_url":"https://clinicaltrials.gov/study/NCT06038578","title":"A Randomized, Multicenter, Open-Label, Phase 2 Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer","has_exemption":false,"start_date":"2023-10-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Toray Industries, Inc","sponsor_slug":"toray-industries-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06112340","publication_url":"https://clinicaltrials.gov/study/NCT06112340","title":"A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)","has_exemption":false,"start_date":"2023-10-11","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Sling Therapeutics, Inc.","sponsor_slug":"sling-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05902988","publication_url":"https://clinicaltrials.gov/study/NCT05902988","title":"A Phase I/II Study of VLS-1488 (an Oral KIF18A Inhibitor) in Subjects With Advanced Cancer","has_exemption":false,"start_date":"2023-10-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Volastra Therapeutics, Inc.","sponsor_slug":"volastra-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05743244","publication_url":"https://clinicaltrials.gov/study/NCT05743244","title":"A Phase 2 Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subtype-Selective JAK Inhibitors for Preservation of Pancreatic β Cell Function in Newly Diagnosed Type 1 Diabetes Mellitus","has_exemption":false,"start_date":"2023-10-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","sponsor_slug":"national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06077877","publication_url":"https://clinicaltrials.gov/study/NCT06077877","title":"A Phase 1/2 First-Time-in-Human, Open-label, Multicenter, Dose Escalation and Expansion Study of the Oral DNA Polymerase Theta Inhibitor (POLQi) GSK4524101 and the PARP Inhibitor (PARPi) Niraparib in Adult Participants With Solid Tumors","has_exemption":false,"start_date":"2023-10-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"GlaxoSmithKline","sponsor_slug":"glaxosmithkline","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06106594","publication_url":"https://clinicaltrials.gov/study/NCT06106594","title":"VOLT CE Mark Study","has_exemption":false,"start_date":"2023-10-24","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Abbott Medical Devices","sponsor_slug":"abbott-medical-devices","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06107361","publication_url":"https://clinicaltrials.gov/study/NCT06107361","title":"Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival","has_exemption":false,"start_date":"2023-11-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Corewell Health East","sponsor_slug":"corewell-health-east","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05924438","publication_url":"https://clinicaltrials.gov/study/NCT05924438","title":"Opti-DOR: A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy","has_exemption":false,"start_date":"2023-11-08","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Professor Francois Venter","sponsor_slug":"professor-francois-venter","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05998135","publication_url":"https://clinicaltrials.gov/study/NCT05998135","title":"Phase II Clinical Trial Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer","has_exemption":false,"start_date":"2023-11-09","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Emory University","sponsor_slug":"emory-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05761223","publication_url":"https://clinicaltrials.gov/study/NCT05761223","title":"A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of FB849 Administered in Subjects With Advanced Solid Tumors Alone and in Combination With Pembrolizumab","has_exemption":false,"start_date":"2023-12-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"1ST Biotherapeutics, Inc.","sponsor_slug":"1st-biotherapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06085183","publication_url":"https://clinicaltrials.gov/study/NCT06085183","title":"An Open-Label, Randomized, Parallel Group Study to Investigate the Influence of Renal Impairment on the Efficacy and Safety of Two Doses of Bludigo™ When Used as an Aid in the Determination of Ureteral Patency","has_exemption":false,"start_date":"2023-12-20","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Prove pharm","sponsor_slug":"prove-pharm","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06187402","publication_url":"https://clinicaltrials.gov/study/NCT06187402","title":"A Phase I/II, First-in-Human (FIH), Open-Label, Multiple Centre Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of LM-24C5 in Patients With Advanced Solid Tumors","has_exemption":false,"start_date":"2023-12-20","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"LaNova Medicines Limited","sponsor_slug":"lanova-medicines-limited","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06511544","publication_url":"https://clinicaltrials.gov/study/NCT06511544","title":"Repetitive Transcranial Magnetic Stimulation of the Ventromedial Prefrontal Cortex to Target Neural Connectivity and Rumination in Treatment-Resistant Major Depressive Disorder: A Pilot Study","has_exemption":false,"start_date":"2024-01-02","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Indiana University","sponsor_slug":"indiana-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05983250","publication_url":"https://clinicaltrials.gov/study/NCT05983250","title":"A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)","has_exemption":false,"start_date":"2024-01-10","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Tenax Therapeutics, Inc.","sponsor_slug":"tenax-therapeutics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06018337","publication_url":"https://clinicaltrials.gov/study/NCT06018337","title":"A Phase 3, Randomized, Multi-center, Open-Label Study of DB-1303 Versus Investigator's Choice Chemotherapy in Human Epidermal Growth Factor Receptor 2 (HER2)-Low, Hormone Receptor Positive (HR+) Metastatic Breast Cancer Patients Whose Disease Has Progressed on Endocrine Therapy (ET) (DYNASTY-Breast02)","has_exemption":false,"start_date":"2024-01-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"DualityBio Inc.","sponsor_slug":"dualitybio-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05631236","publication_url":"https://clinicaltrials.gov/study/NCT05631236","title":"Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy","has_exemption":false,"start_date":"2024-01-29","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"VA Office of Research and Development","sponsor_slug":"va-office-of-research-and-development","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT05968157","publication_url":"https://clinicaltrials.gov/study/NCT05968157","title":"MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick","has_exemption":false,"start_date":"2024-02-04","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of Massachusetts, Worcester","sponsor_slug":"university-of-massachusetts-worcester","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06732570","publication_url":"https://clinicaltrials.gov/study/NCT06732570","title":"Effect of High Intensity Laser on Shoulder Impingement Syndrome in Adolescents","has_exemption":false,"start_date":"2024-02-18","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Cairo University","sponsor_slug":"cairo-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04453033","publication_url":"https://clinicaltrials.gov/study/NCT04453033","title":"Double-blind, Randomized Controlled Trial to Demonstrate Efficacy of Celeste® Specialized Phototherapy in Treating Parkinson's Disease.","has_exemption":false,"start_date":"2024-02-26","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"PhotoPharmics, Inc.","sponsor_slug":"photopharmics-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06497127","publication_url":"https://clinicaltrials.gov/study/NCT06497127","title":"A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Study to Evaluate the Efficacy and Safety of Subcutaneously Administered BW-00112 in Patients With Mixed Dyslipidemia","has_exemption":false,"start_date":"2024-02-28","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Shanghai Argo Biopharmaceutical Co., Ltd.","sponsor_slug":"shanghai-argo-biopharmaceutical-co-ltd","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06206148","publication_url":"https://clinicaltrials.gov/study/NCT06206148","title":"Comparison of Methods for Recording Post Operative Pain: A Prospective Randomized Trial","has_exemption":false,"start_date":"2024-03-01","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of California, San Francisco","sponsor_slug":"university-of-california-san-francisco","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06507449","publication_url":"https://clinicaltrials.gov/study/NCT06507449","title":"The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation","has_exemption":false,"start_date":"2024-03-07","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Medical University of Silesia","sponsor_slug":"medical-university-of-silesia","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06495684","publication_url":"https://clinicaltrials.gov/study/NCT06495684","title":"Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)","has_exemption":false,"start_date":"2024-03-12","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"University of New Mexico","sponsor_slug":"university-of-new-mexico","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06318286","publication_url":"https://clinicaltrials.gov/study/NCT06318286","title":"First-line Pembrolizumab Plus Platinum Doublet Chemotherapy With Lenvatinib in Unresectable Malignant Pleural Mesothelioma：Multi-Institutional, Single-Arm Phase 2 Trial","has_exemption":false,"start_date":"2024-03-13","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Hyogo Medical University","sponsor_slug":"hyogo-medical-university","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04850118","publication_url":"https://clinicaltrials.gov/study/NCT04850118","title":"A Randomized, Controlled, Masked, Multi-center Study Evaluating the Efficacy, Safety, and Tolerability of Two Doses of AGTC-501 Compared to an Untreated Control Group in Male Participants With X-linked Retinitis Pigmentosa","has_exemption":false,"start_date":"2024-03-14","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Beacon Therapeutics","sponsor_slug":"beacon-therapeutics","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT04781140","publication_url":"https://clinicaltrials.gov/study/NCT04781140","title":"A Phase 4, Randomized, Double-Blind, Multicenter, Placebo-Controlled, Parallel-Group Study of the Efficacy and Safety of SPN-812 in Preschool-Age Children (4 to 5 Years Old) With Attention-Deficit/Hyperactivity Disorder (ADHD)","has_exemption":false,"start_date":"2024-03-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Supernus Pharmaceuticals, Inc.","sponsor_slug":"supernus-pharmaceuticals-inc","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06057675","publication_url":"https://clinicaltrials.gov/study/NCT06057675","title":"Subcutaneous Tranexamic Acid in Nasal Mohs Local Flap Reconstruction: Perioperative Bleeding, Edema, and Ecchymosis","has_exemption":false,"start_date":"2024-03-19","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"Vanderbilt University Medical Center","sponsor_slug":"vanderbilt-university-medical-center","status":"ongoing","is_pact":false,"days_late":null},{"registry_id":"NCT06447844","publication_url":"https://clinicaltrials.gov/study/NCT06447844","title":"OsteoGen® Plug vs Freeze-dried Bone Allograft With Collagen Barrier for Alveolar Ridge Preservation (ARP): A Randomized Controlled Trial","has_exemption":false,"start_date":"2024-03-28","completion_date":"2026-06-30","has_results":false,"results_due":false,"sponsor_name":"McGuire Institute","sponsor_slug":"mcguire-institute","status":"ongoing","is_pact":false,"days_late":null}]}